sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4ce9 | O3N | Integrase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4ce9 | O3N | Integrase | / | 1.000 | |
| 4cif | JDX | Integrase | / | 0.688 | |
| 4cjk | H39 | Integrase | / | 0.688 | |
| 4ceq | QCH | Integrase | / | 0.684 | |
| 4cfa | WOP | Integrase | / | 0.682 | |
| 4ced | 9NS | Integrase | / | 0.663 | |
| 4cig | X0P | Integrase | / | 0.658 | |
| 3zsr | O3N | Integrase | / | 0.649 | |
| 4cez | O3N | Integrase | / | 0.649 | |
| 4cf2 | 3GM | Integrase | / | 0.648 | |
| 4cf0 | O5U | Integrase | / | 0.643 | |
| 4cfc | 7NV | Integrase | / | 0.636 | |
| 3zsw | ZSW | Integrase | / | 0.634 | |
| 3zsv | ZSV | Integrase | / | 0.627 | |
| 4ceb | ZSV | Integrase | / | 0.627 | |
| 4cfb | OM3 | Integrase | / | 0.627 | |
| 4cgj | NZL | Integrase | / | 0.627 | |
| 3zt0 | ZT0 | Integrase | / | 0.626 | |
| 4cea | ZSW | Integrase | / | 0.624 | |
| 4cgd | 8P3 | Integrase | / | 0.620 | |
| 4cef | D0T | Integrase | / | 0.613 | |
| 4cj3 | E4F | Integrase | / | 0.606 | |
| 4cgg | K5Q | Integrase | / | 0.603 | |
| 3zsz | OM2 | Integrase | / | 0.601 | |
| 4cer | VL4 | Integrase | / | 0.601 | |
| 3zsq | O4N | Integrase | / | 0.600 | |
| 4ck1 | OM1 | Integrase | / | 0.596 | |
| 4ck2 | NVU | Integrase | / | 0.596 | |
| 4ces | NFW | Integrase | / | 0.595 | |
| 4cjp | 4D2 | Integrase | / | 0.591 | |
| 4cjf | RVN | Integrase | / | 0.590 | |
| 4cjr | FYM | Integrase | / | 0.586 | |
| 3zsx | N44 | Integrase | / | 0.583 | |
| 3zcm | PX3 | Integrase | / | 0.582 | |
| 4cie | Y7N | Integrase | / | 0.582 | |
| 4ceo | G0T | Integrase | / | 0.579 | |
| 4cju | JNS | Integrase | / | 0.577 | |
| 4cf8 | V7H | Integrase | / | 0.575 | |
| 4chy | C5Q | Integrase | / | 0.575 | |
| 3zt2 | ZT2 | Integrase | / | 0.573 | |
| 4cjs | L0Y | Integrase | / | 0.572 | |
| 3zsy | OM3 | Integrase | / | 0.569 | |
| 4cgi | NZL | Integrase | / | 0.569 | |
| 4cje | Q31 | Integrase | / | 0.566 | |
| 4cjq | VXO | Integrase | / | 0.566 | |
| 4ck3 | K1T | Integrase | / | 0.561 | |
| 4cf1 | IY7 | Integrase | / | 0.556 | |
| 4cj4 | S3G | Integrase | / | 0.556 | |
| 4cee | B0T | Integrase | / | 0.553 | |
| 4cgh | LOZ | Integrase | / | 0.551 | |
| 3zt3 | ZT4 | Integrase | / | 0.549 | |
| 4cfd | S8Y | Integrase | / | 0.546 | |
| 4cec | 2SS | Integrase | / | 0.540 | |
| 4cj5 | 4VW | Integrase | / | 0.537 | |
| 4chq | CWU | Integrase | / | 0.516 | |
| 3zt1 | OM1 | Integrase | / | 0.515 | |
| 4mdh | NAD | Malate dehydrogenase, cytoplasmic | 1.1.1.37 | 0.504 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.502 | |
| 2bgj | FAD | NADPH:ferredoxin reductase | / | 0.495 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.494 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.492 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.491 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.491 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.490 | |
| 4p8r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.490 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.485 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.484 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.484 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.484 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.484 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.483 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.483 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.482 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.482 | |
| 1nqo | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.481 | |
| 2vnj | FAD | NADPH:ferredoxin reductase | / | 0.481 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.481 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.480 | |
| 4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.480 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.479 | |
| 2wxv | WXV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.479 | |
| 3cos | NAD | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.479 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.479 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.478 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.478 | |
| 2vnh | FAD | NADPH:ferredoxin reductase | / | 0.478 | |
| 3e5r | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic | 1.2.1.12 | 0.478 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.478 | |
| 3ids | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.478 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.478 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.478 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.477 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.476 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.476 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.476 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.475 | |
| 2vnk | FAD | NADPH:ferredoxin reductase | / | 0.475 | |
| 4aqc | 88A | Tyrosine-protein kinase JAK2 | / | 0.475 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.475 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.474 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.474 | |
| 4ng2 | OHN | Transcriptional activator protein LasR | / | 0.474 | |
| 5dp2 | NAP | CurF | / | 0.474 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.473 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.473 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.473 | |
| 4rrr | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.473 | |
| 2trt | TAC | Tetracycline repressor protein class D | / | 0.472 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.472 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.471 | |
| 3cif | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.471 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.471 | |
| 3owa | FAD | Acyl-CoA dehydrogenase | / | 0.471 | |
| 4btj | ADP | Tau-tubulin kinase 1 | 2.7.11.1 | 0.471 | |
| 5ao1 | DG3 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.471 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.470 | |
| 4geb | 0LD | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.470 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.470 | |
| 1u8f | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.469 | |
| 1z1f | STL | Resveratrol synthase | / | 0.469 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.469 | |
| 3e8x | NAP | BH1520 protein | / | 0.469 | |
| 3gu8 | 3GU | Death-associated protein kinase 1 | 2.7.11.1 | 0.469 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.469 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.469 | |
| 4hxy | NDP | Plm1 | / | 0.469 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.469 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.468 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.468 | |
| 3otf | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.468 | |
| 3r6s | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.468 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.468 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.467 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.467 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.467 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1nq5 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.466 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.466 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.466 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.466 | |
| 3mg3 | ECH | Orange carotenoid-binding protein | / | 0.466 | |
| 1gd1 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.465 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.465 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.465 | |
| 2fn7 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.465 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.465 | |
| 2xrw | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.465 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.465 | |
| 3u4c | NDP | NADPH-dependent reductase BacG | / | 0.465 | |
| 3w32 | W32 | Epidermal growth factor receptor | 2.7.10.1 | 0.465 | |
| 4k9d | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.465 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.464 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.464 | |
| 2pvn | P63 | Casein kinase II subunit alpha | 2.7.11.1 | 0.464 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.464 | |
| 4cgf | UJ6 | Integrase | / | 0.464 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.464 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.463 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.463 | |
| 2ix5 | FAD | Acyl-coenzyme A oxidase 4, peroxisomal | 1.3.3.6 | 0.463 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.463 | |
| 2y8l | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.463 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.463 | |
| 4dja | FAD | (6-4) photolyase | / | 0.463 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.463 | |
| 5hsa | FAS | Alcohol oxidase 1 | 1.1.3.13 | 0.463 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.462 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.462 | |
| 3ak4 | NAD | NADH-dependent quinuclidinone reductase | / | 0.462 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.462 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.462 | |
| 4c58 | 824 | Cyclin-G-associated kinase | 2.7.11.1 | 0.462 | |
| 4nd4 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.462 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.461 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.461 | |
| 2gnh | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.461 | |
| 3eku | CY9 | Actin-5C | / | 0.461 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.461 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.461 | |
| 3vwd | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.461 | |
| 3zuy | TCH | Transporter | / | 0.461 | |
| 4b4d | FAD | Ferredoxin-NADP reductase | / | 0.461 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.461 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.461 | |
| 3cps | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.460 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.460 | |
| 3elj | GS7 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.460 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.460 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.460 | |
| 4mok | FAD | Pyranose 2-oxidase | / | 0.460 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.460 | |
| 1gqt | ACP | Ribokinase | / | 0.459 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.459 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 2ii5 | CO6 | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial | 2.3.1.168 | 0.459 | |
| 2v9j | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.459 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.459 | |
| 3r5y | F42 | Uncharacterized protein | / | 0.459 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.459 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.459 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.459 | |
| 1sny | NAP | LD36273p | / | 0.458 | |
| 1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.458 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.458 | |
| 2rm2 | W43 | Genome polyprotein | / | 0.458 | |
| 2z54 | AB1 | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.458 | |
| 3up5 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.458 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.458 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.458 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.458 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.458 | |
| 4xcv | NDP | Probable hydroxyacid dehydrogenase protein | / | 0.458 | |
| 4z4p | SAH | Histone-lysine N-methyltransferase 2D | 2.1.1.43 | 0.458 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 1p0y | SAH | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.457 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.457 | |
| 2ohv | NHL | Glutamate racemase | / | 0.457 | |
| 2pvj | P44 | Casein kinase II subunit alpha | 2.7.11.1 | 0.457 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.457 | |
| 2xaa | NAD | Secondary alcohol dehydrogenase | / | 0.457 | |
| 3dbv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.457 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.457 | |
| 3k2b | NAD | Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic | 1.2.1.13 | 0.457 | |
| 3nu9 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.457 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.457 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.457 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.457 | |
| 4nfs | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.457 | |
| 4o0w | ADN | Aurora kinase A | 2.7.11.1 | 0.457 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.457 | |
| 1a8p | FAD | Ferredoxin--NADP reductase | / | 0.456 | |
| 1ha3 | MAU | Elongation factor Tu-A | / | 0.456 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.456 | |
| 2hwr | DRD | Peroxisome proliferator-activated receptor gamma | / | 0.456 | |
| 2v13 | C40 | Renin | 3.4.23.15 | 0.456 | |
| 2vz6 | FEF | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.7.11.17 | 0.456 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.456 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.456 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.456 | |
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.456 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.456 | |
| 4fg8 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.456 | |
| 4l7f | 1V5 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.456 | |
| 4yt5 | H4M | H(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338 | / | 0.456 | |
| 4zgs | NAD | Putative D-lactate dehydrogenase | / | 0.456 | |
| 1a7k | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.455 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.455 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.455 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.455 | |
| 1nlm | UD1 | UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase | / | 0.455 | |
| 1u4o | NDD | L-lactate dehydrogenase | 1.1.1.27 | 0.455 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.455 | |
| 2gsd | NAD | Formate dehydrogenase | / | 0.455 | |
| 3bgb | LJG | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 3ecg | 065 | Gag-Pol polyprotein | 3.4.23.47 | 0.455 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.455 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.455 | |
| 3lzs | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 3s56 | ROC | Protease | / | 0.455 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.455 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.455 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.454 | |
| 1bdl | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 1o8c | NDP | Probable acrylyl-CoA reductase AcuI | 1.3.1.84 | 0.454 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.454 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.454 | |
| 2cda | NAP | Glucose 1-dehydrogenase | / | 0.454 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.454 | |
| 2hma | SAM | tRNA-specific 2-thiouridylase MnmA | / | 0.454 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.454 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.454 | |
| 3be9 | P04 | Casein kinase II subunit alpha | 2.7.11.1 | 0.454 | |
| 3fnl | SHA | Lactoperoxidase | / | 0.454 | |
| 3jqp | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.454 | |
| 3ksd | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1 | / | 0.454 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.454 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.454 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.454 | |
| 4e4q | RRH | Peroxisome proliferator-activated receptor gamma | / | 0.454 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.454 | |
| 4jin | 1L7 | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.454 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.454 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.454 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.454 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.454 | |
| 1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.453 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.453 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.453 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.453 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.453 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.453 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.453 | |
| 3d8b | ADP | Fidgetin-like protein 1 | 3.6.4 | 0.453 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.453 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 4f9m | FCM | Peroxisome proliferator-activated receptor gamma | / | 0.453 | |
| 4fr4 | STU | Serine/threonine-protein kinase 32A | 2.7.11.1 | 0.453 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.453 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.453 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.452 | |
| 1j1c | ADP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.452 | |
| 1p0h | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.452 | |
| 1pow | FAD | Pyruvate oxidase | 1.2.3.3 | 0.452 | |
| 1pzh | NAD | Lactate dehydrogenase | / | 0.452 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.452 | |
| 1sow | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.452 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.452 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.452 | |
| 2j83 | BAT | Ulilysin | 3.4.24 | 0.452 | |
| 2o12 | FMN | Chorismate synthase | / | 0.452 | |
| 3lpb | NVB | Tyrosine-protein kinase JAK2 | / | 0.452 | |
| 3mvm | 39P | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 4anm | WUL | Casein kinase II subunit alpha | 2.7.11.1 | 0.452 | |
| 4bib | IEO | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.452 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.452 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.452 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.452 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.452 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.451 | |
| 1o2g | 696 | Prothrombin | 3.4.21.5 | 0.451 | |
| 1ppj | ANY | Cytochrome b | / | 0.451 | |
| 2am2 | 2LG | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.451 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.451 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.451 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.451 | |
| 2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.451 | |
| 3a3y | OBN | Sodium/potassium-transporting ATPase subunit alpha | / | 0.451 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.451 | |
| 3i60 | E86 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.451 | |
| 3ijo | B4D | Glutamate receptor 2 | / | 0.451 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.451 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.451 | |
| 4dfn | 0K1 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.451 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.451 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.451 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.451 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.451 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 5a3b | APR | SIR2 family protein | / | 0.451 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.450 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.450 | |
| 1ml3 | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.450 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.450 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.450 | |
| 2e08 | SAH | Diphthine synthase | / | 0.450 | |
| 2ekl | NAD | D-3-phosphoglycerate dehydrogenase | / | 0.450 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.450 | |
| 2uzl | C94 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.450 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.450 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.450 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.450 | |
| 4eki | 0QK | Histone-lysine N-methyltransferase, H3 lysine-79 specific | 2.1.1.43 | 0.450 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.450 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 4gj3 | 0XP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.450 | |
| 4hge | 15V | Tyrosine-protein kinase JAK2 | / | 0.450 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.450 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.450 | |
| 4qna | X11 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.450 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.450 | |
| 4yer | ADP | Antibiotic ABC transporter, ATP-binding protein, putative | / | 0.450 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.450 | |
| 5cdt | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.450 | |
| 1b16 | NAQ | Alcohol dehydrogenase | 1.1.1.1 | 0.449 | |
| 1j1b | ANP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.449 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.449 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.449 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.449 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.449 | |
| 1rbz | KT5 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.449 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.449 | |
| 2bjh | FER | Feruloyl esterase A | 3.1.1.73 | 0.449 | |
| 2e8h | SAH | Diphthine synthase | / | 0.449 | |
| 2hsd | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.449 | |
| 2ien | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.449 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.449 | |
| 3hbb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.449 | |
| 3jv7 | NAD | Secondary alcohol dehydrogenase | / | 0.449 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.449 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3vye | VYE | Renin | 3.4.23.15 | 0.449 | |
| 4cpd | NAD | Alcohol dehydrogenase | / | 0.449 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.449 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.449 | |
| 4x28 | FDA | Acyl-CoA dehydrogenase FadE26 | / | 0.449 | |
| 4x28 | FDA | Acyl-CoA dehydrogenase FadE27 | / | 0.449 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.448 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.448 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.448 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.448 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.448 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.448 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.448 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.448 | |
| 1tdu | CB3 | Thymidylate synthase | / | 0.448 | |
| 1znq | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.448 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.448 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.448 | |
| 2ijm | ADP | Focal adhesion kinase 1 | 2.7.10.2 | 0.448 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.448 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.448 | |
| 2oax | SNL | Mineralocorticoid receptor | / | 0.448 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.448 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.448 | |
| 2ydj | YDJ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.448 | |
| 3buv | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.448 | |
| 3eyh | IZA | Tyrosine-protein kinase JAK1 | / | 0.448 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.448 | |
| 3mjh | GTP | Ras-related protein Rab-5A | / | 0.448 | |
| 3o9h | K2E | Gag-Pol polyprotein | / | 0.448 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 3so9 | 017 | Pol protein | / | 0.448 | |
| 3uax | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.448 | |
| 4awi | AQ2 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.448 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.448 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.448 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.448 | |
| 4qof | FMN | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.448 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.448 | |
| 1p0h | COA | Mycothiol acetyltransferase | 2.3.1.189 | 0.447 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.447 | |
| 1x27 | ASP_TYR_VAL_HIS_PTR | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.447 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.447 | |
| 2emu | SAH | Diphthine synthase | / | 0.447 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.447 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.447 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.447 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.447 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.447 | |
| 3oxv | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 3wle | NAD | (R)-specific carbonyl reductase | / | 0.447 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
| 4bqj | XKL | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.447 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.447 | |
| 4jji | NAD | Alcohol dehydrogenase class-3 | / | 0.447 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.447 | |
| 1fdt | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
| 1guf | NDP | Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial | 1.3.1.10 | 0.446 | |
| 1u1d | 181 | Uridine phosphorylase | 2.4.2.3 | 0.446 | |
| 1uxj | NAD | Malate dehydrogenase | / | 0.446 | |
| 2ejj | SAH | Diphthine synthase | / | 0.446 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.446 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.446 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 2owu | SAH | Diphthine synthase | / | 0.446 | |
| 2tps | TPS | Thiamine-phosphate synthase | / | 0.446 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.446 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.446 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.446 | |
| 3hy7 | 097 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.446 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.446 | |
| 3up0 | D7S | aceDAF-12 | / | 0.446 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.446 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.446 | |
| 4c4o | NAD | SADH | / | 0.446 | |
| 4fcr | 0TM | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 4fv6 | E57 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.446 | |
| 4kuh | CAA | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.446 | |
| 5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.446 | |
| 1b8u | NAD | Malate dehydrogenase | / | 0.445 | |
| 1cer | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.445 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.445 | |
| 1ege | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.445 | |
| 1h74 | AGS | Homoserine kinase | 2.7.1.39 | 0.445 | |
| 1i24 | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.445 | |
| 1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.445 | |
| 1qx4 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.445 | |
| 2cbr | A80 | Cellular retinoic acid-binding protein 1 | / | 0.445 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.445 | |
| 2oz5 | 7XY | Uncharacterized protein | / | 0.445 | |
| 2pvh | P19 | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 2qnq | QN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 2xs0 | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.445 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.445 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.445 | |
| 3l9m | L9M | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 3lvf | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1 | / | 0.445 | |
| 3qd0 | 3Q4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.445 | |
| 3qn8 | NI7 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 3qof | GDP | Atlastin-1 | 3.6.5 | 0.445 | |
| 3vfq | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.445 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4ejv | LCL | Transcriptional regulator TcaR | / | 0.445 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.445 | |
| 4jb1 | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.445 | |
| 4xwt | U5P | Ribonuclease J | / | 0.445 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.445 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.445 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.445 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.444 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.444 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.444 | |
| 2aib | ERG | Beta-elicitin cinnamomin | / | 0.444 | |
| 2bx8 | AZQ | Serum albumin | / | 0.444 | |
| 2bxo | OPB | Serum albumin | / | 0.444 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.444 | |
| 2y8q | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.444 | |
| 3m6i | NAD | L-arabinitol 4-dehydrogenase | 1.1.1.12 | 0.444 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.444 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.444 | |
| 3qwk | X62 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 3rni | 21Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.444 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.444 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 4e9a | QAP | Peptide deformylase | / | 0.444 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.444 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.444 | |
| 4obw | SAM | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial | / | 0.444 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.444 | |
| 6cts | CIC | Citrate synthase, mitochondrial | 2.3.3.1 | 0.444 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.443 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.443 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.443 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.443 | |
| 1pag | FMP | Antiviral protein I | 3.2.2.22 | 0.443 | |
| 1sbg | IM1 | Gag-Pol polyprotein | / | 0.443 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.443 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.443 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.443 | |
| 1ysz | NEC | Endoplasmin | / | 0.443 | |
| 2c6t | DT5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.443 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.443 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.443 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.443 | |
| 2qhm | 7CS | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.443 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.443 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.443 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.443 | |
| 3qd4 | 3Q6 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.443 | |
| 3t8o | ATP | Rhodopsin kinase | / | 0.443 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.443 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.443 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 4ach | KDI | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.443 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.443 | |
| 4bgg | 844 | Activin receptor type-1 | 2.7.11.30 | 0.443 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.443 | |
| 4gdd | NAI | UDP-galactopyranose mutase | / | 0.443 | |
| 4hzp | COA | Conserved hypthetical protein | / | 0.443 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.443 | |
| 5hes | 032 | Mitogen-activated protein kinase kinase kinase 20 | 2.7.11.25 | 0.443 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.443 | |
| 1dna | CB3 | Thymidylate synthase | / | 0.442 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.442 | |
| 1jtu | LYB | Thymidylate synthase | / | 0.442 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1pmn | 984 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.442 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.442 | |
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.442 | |
| 1x8v | ESL | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.442 | |
| 2fgk | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.442 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.442 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.442 | |
| 2ojg | 19A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.442 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.442 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.442 | |
| 2ydi | YDI | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.442 | |
| 2zfn | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.442 | |
| 3a28 | NAD | L-2,3-butanediol dehydrogenase | 1.1.1.76 | 0.442 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.442 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.442 | |
| 3cbl | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.442 | |
| 3hrc | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 3i7e | DJR | Gag-Pol polyprotein | / | 0.442 | |
| 3lsm | SFD | Pyranose 2-oxidase | / | 0.442 | |
| 3o15 | 3NM | Thiamine-phosphate synthase | / | 0.442 | |
| 3rq6 | APR | ADP-dependent (S)-NAD(P)H-hydrate dehydratase | / | 0.442 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.442 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.442 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.442 | |
| 4aot | GW8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.442 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.442 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.442 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.441 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.441 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.441 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.441 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.441 | |
| 1ve3 | SAM | Uncharacterized protein | / | 0.441 | |
| 2aa3 | AP0 | L-lactate dehydrogenase | / | 0.441 | |
| 2bd0 | NAP | Sepiapterin reductase | / | 0.441 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.441 | |
| 2c69 | CT8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 2dsh | SAH | Diphthine synthase | / | 0.441 | |
| 2ft0 | ACO | dTDP-fucosamine acetyltransferase | / | 0.441 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.441 | |
| 2xik | J60 | Serine/threonine-protein kinase 25 | 2.7.11.1 | 0.441 | |
| 2xj2 | 985 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 2xy9 | 3ES | Angiotensin-converting enzyme | 3.2.1 | 0.441 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.441 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.441 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.441 | |
| 3c16 | FOK | Adenylate cyclase type 2 | / | 0.441 | |
| 3c16 | FOK | Adenylate cyclase type 5 | / | 0.441 | |
| 3dxm | N24 | Actin-related protein 3 | / | 0.441 | |
| 3hmm | 855 | TGF-beta receptor type-1 | 2.7.11.30 | 0.441 | |
| 3ijr | NAD | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.441 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.441 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.441 | |
| 3lct | ADP | ALK tyrosine kinase receptor | 2.7.10.1 | 0.441 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.441 | |
| 3te4 | ACO | Dopamine N-acetyltransferase | / | 0.441 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.441 | |
| 3v2u | ATP | Protein GAL3 | / | 0.441 | |
| 3zdf | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.441 | |
| 3zdu | 38R | Cyclin-dependent kinase-like 3 | 2.7.11.22 | 0.441 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.441 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.441 | |
| 4bie | IE6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.441 | |
| 4em9 | TCE | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 4fv0 | EK3 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.441 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.441 | |
| 4jia | 1K3 | Tyrosine-protein kinase JAK2 | / | 0.441 | |
| 4qec | NAP | ElxO | / | 0.441 | |
| 4xd2 | NAI | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.441 | |
| 5c41 | ACP | Ribokinase | / | 0.441 | |
| 5iqi | GNP | Bifunctional AAC/APH | 2.3.1 | 0.441 | |
| 1b14 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.440 | |
| 1bv7 | XV6 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1e3l | NAD | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.440 | |
| 1gyp | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.440 | |
| 1h61 | PDN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 1hf3 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 | |
| 1k6v | XN2 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1npt | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.440 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 1phh | FAD | p-hydroxybenzoate hydroxylase | / | 0.440 | |
| 1qf5 | RPL | Adenylosuccinate synthetase | / | 0.440 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.440 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.440 | |
| 1z1r | HBH | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 2b4r | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.440 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.440 | |
| 2ek7 | SAH | Diphthine synthase | / | 0.440 | |
| 2el0 | SAH | Diphthine synthase | / | 0.440 | |
| 2fzm | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.440 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.440 | |
| 2g9u | G27 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.440 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.440 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.440 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.440 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.440 | |
| 3ggo | NAI | Prephenate dehydrogenase | / | 0.440 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.440 | |
| 3nie | ANP | Mitogen-activated protein kinase | / | 0.440 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.440 | |
| 3qxp | X64 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.440 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.440 | |
| 3zep | 1NX | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.440 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.440 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.440 | |
| 4kio | G5K | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.440 | |
| 4lrj | ANP | Uncharacterized protein | / | 0.440 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.440 | |
| 6adh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 |