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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4c3f7KWTyrosine-protein kinase Lck2.7.10.2

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4c3f7KWTyrosine-protein kinase Lck2.7.10.21.000
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.517
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.515
5e8wSTUTGF-beta receptor type-12.7.11.300.514
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.511
2ghlLIBMitogen-activated protein kinase 14/0.510
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.508
1bwsNDPGDP-L-fucose synthase/0.507
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.507
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.507
4gk2L66Ephrin type-A receptor 32.7.10.10.506
3gu83GUDeath-associated protein kinase 12.7.11.10.504
2vwz7X6Ephrin type-B receptor 42.7.10.10.502
1u4dDBQActivated CDC42 kinase 1/0.501
3hllI45Mitogen-activated protein kinase 14/0.501
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.499
4f650S9Fibroblast growth factor receptor 1/0.499
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.497
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.497
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.497
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.496
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.496
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.496
2vx07X7Ephrin type-B receptor 42.7.10.10.495
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.495
1vjy460TGF-beta receptor type-12.7.11.300.490
2xvdAS6Ephrin type-B receptor 42.7.10.10.490
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.489
1oiyN41Cyclin-dependent kinase 22.7.11.220.489
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.488
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.488
2j0m4STFocal adhesion kinase 12.7.10.20.488
1zz2B11Mitogen-activated protein kinase 14/0.487
2pwlACPFibroblast growth factor receptor 2/0.487
2vx17X8Ephrin type-B receptor 42.7.10.10.487
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.487
2wotZZGTGF-beta receptor type-12.7.11.300.486
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.486
3uyt0CKCasein kinase I isoform delta2.7.11.10.485
4qmpDKISerine/threonine-protein kinase 242.7.11.10.485
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.484
3tucFPWTyrosine-protein kinase SYK2.7.10.20.484
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.484
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.483
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.483
4qmwKS1Serine/threonine-protein kinase 242.7.11.10.483
4dymIYZActivin receptor type-12.7.11.300.482
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.481
4gk3L87Ephrin type-A receptor 32.7.10.10.481
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.480
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.480
3w33W19Epidermal growth factor receptor2.7.10.10.480
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.480
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.479
2q59240Peroxisome proliferator-activated receptor gamma/0.479
3hx4ANPCalmodulin-domain protein kinase 1/0.479
4gmy0X5Tyrosine-protein kinase JAK2/0.479
3c4xATPRhodopsin kinase/0.478
3gubGUBDeath-associated protein kinase 12.7.11.10.478
4y93746Tyrosine-protein kinase/0.478
1rfvADPPyridoxal kinase2.7.1.350.477
1unlRRCCyclin-dependent-like kinase 52.7.11.10.477
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.477
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.477
3dt1P40Mitogen-activated protein kinase 14/0.477
3l8p0CEAngiopoietin-1 receptor2.7.10.10.477
3mtfA3FActivin receptor type-12.7.11.300.477
4bgg844Activin receptor type-12.7.11.300.477
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.477
4g2fC07Ephrin type-A receptor 32.7.10.10.477
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.477
1py5PY1TGF-beta receptor type-12.7.11.300.476
4nk92K5Fibroblast growth factor receptor 1/0.476
1jpaANPEphrin type-B receptor 22.7.10.10.475
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.475
2vn0TDZCytochrome P450 2C8/0.475
2vwx7X4Ephrin type-B receptor 42.7.10.10.475
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.475
2vwy7X5Ephrin type-B receptor 42.7.10.10.474
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.474
4kzoNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.474
1bygSTUTyrosine-protein kinase CSK/0.473
1jioDEB6-deoxyerythronolide B hydroxylase/0.473
3s1dZIRCytokinin dehydrogenase 11.5.99.120.473
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.472
2c0oL2GTyrosine-protein kinase HCK2.7.10.20.472
2itpAEEEpidermal growth factor receptor2.7.10.10.472
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.472
5e8xSTUTGF-beta receptor type-12.7.11.300.472
2x9fX9FEphrin type-B receptor 42.7.10.10.471
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.471
3fln3FNMitogen-activated protein kinase 14/0.471
3nww3NWMitogen-activated protein kinase 14/0.471
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.470
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.469
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.469
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.469
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.469
4i22IREEpidermal growth factor receptor2.7.10.10.469
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.468
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.468
3hmm855TGF-beta receptor type-12.7.11.300.468
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.468
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.468
1kkq471Peroxisome proliferator-activated receptor alpha/0.467
1zeoC01Peroxisome proliferator-activated receptor gamma/0.467
1zmcNADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.467
2x1nX1NCyclin-dependent kinase 22.7.11.220.467
4ia7BIVVitamin D3 receptor A/0.467
1c6yMK1Protease/0.466
2x2lX2LProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.466
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.466
3flwFLWMitogen-activated protein kinase 14/0.466
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.465
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.465
1j39UPGDNA beta-glucosyltransferase/0.465
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.465
2y6o1N1Ephrin type-A receptor 42.7.10.10.465
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.465
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.464
2hb7O1CVitamin D3 receptor/0.464
2v7a627Tyrosine-protein kinase ABL12.7.10.20.464
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.464
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.464
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.464
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.464
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.464
4lopSB4Mitogen-activated protein kinase 14/0.464
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.464
1zys199Serine/threonine-protein kinase Chk12.7.11.10.463
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.463
2oapANPType II secretion system protein (GspE-2)/0.463
2vww7X2Ephrin type-B receptor 42.7.10.10.463
3eljGS7Mitogen-activated protein kinase 82.7.11.240.463
4aacAAVMitogen-activated protein kinase 14/0.463
4hnf16WCasein kinase I isoform delta2.7.11.10.463
4ic7ANPMitogen-activated protein kinase 72.7.11.240.463
4q71FADBifunctional protein PutA/0.463
2etm7PYFocal adhesion kinase 12.7.10.20.462
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.462
2w06FRVCyclin-dependent kinase 22.7.11.220.462
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.462
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.462
4hge15VTyrosine-protein kinase JAK2/0.462
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.461
2xyuQ9GEphrin type-A receptor 42.7.10.10.461
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.461
3gw9VNILanosterol 14-alpha-demethylase/0.461
3i60E86Mitogen-activated protein kinase 12.7.11.240.461
3uzp0CKCasein kinase I isoform delta2.7.11.10.461
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.461
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.461
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
4fod0UVALK tyrosine kinase receptor2.7.10.10.461
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.461
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.461
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.461
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.460
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.460
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
2hog710Serine/threonine-protein kinase Chk12.7.11.10.460
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.460
4bb432WEphrin type-B receptor 42.7.10.10.460
4ruoBIVVitamin D3 receptor A/0.460
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.459
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.459
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.459
2iw84SPCyclin-dependent kinase 22.7.11.220.459
2x2mX2MProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.459
1e3eNAIAlcohol dehydrogenase 41.1.1.10.458
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.458
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.458
1oirHDYCyclin-dependent kinase 22.7.11.220.458
2izrBRKCasein kinase I isoform gamma-32.7.11.10.458
2j0k4STFocal adhesion kinase 12.7.10.20.458
3oev3OEProteasome subunit beta type-53.4.25.10.458
3oev3OEProteasome subunit beta type-63.4.25.10.458
3oom507Activin receptor type-12.7.11.300.458
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.458
3vrtYS2Vitamin D3 receptor/0.458
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.458
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.458
5eaiFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.458
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.457
3h3cP1EProtein-tyrosine kinase 2-beta2.7.10.20.457
3sdi3SDProteasome subunit beta type-53.4.25.10.457
3sdi3SDProteasome subunit beta type-63.4.25.10.457
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.457
4a6nFADTetX family tetracycline inactivation enzyme/0.457
4e93GUITyrosine-protein kinase Fes/Fps2.7.10.20.457
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.457
4ia2BIVVitamin D3 receptor A/0.457
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.457
2b7aIZATyrosine-protein kinase JAK2/0.456
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.456
2ivvPP1Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.456
3lqfNADGalactitol dehydrogenase/0.456
4c02TAKActivin receptor type-12.7.11.300.456
4gk4L90Ephrin type-A receptor 32.7.10.10.456
4hvh19RTyrosine-protein kinase JAK32.7.10.20.456
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.456
4j97ACPFibroblast growth factor receptor 2/0.456
4wuoNAD3-isopropylmalate dehydrogenase1.1.1.850.456
1nvtNAPShikimate dehydrogenase (NADP(+))/0.455
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.455
2ittAEEEpidermal growth factor receptor2.7.10.10.455
2of2547Tyrosine-protein kinase Lck2.7.10.20.455
2oj9BMIInsulin-like growth factor 1 receptor2.7.10.10.455
2ywwATPAspartate carbamoyltransferase regulatory chain/0.455
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.455
3gxlQIGTGF-beta receptor type-12.7.11.300.455
3kb1ADPIron-sulfur cluster carrier protein/0.455
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.455
3qlfPD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.455
4ewqMWLMitogen-activated protein kinase 14/0.455
4ia3BIVVitamin D3 receptor A/0.455
4k33ACPFibroblast growth factor receptor 32.7.10.10.455
4uymVOR14-alpha sterol demethylase Cyp51B/0.455
1hncGDNGlutathione S-transferase Mu 22.5.1.180.454
1pmn984Mitogen-activated protein kinase 102.7.11.240.454
1zgyBRLPeroxisome proliferator-activated receptor gamma/0.454
2bkzSBCCyclin-dependent kinase 22.7.11.220.454
2c27ACOMycothiol acetyltransferase2.3.1.1890.454
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.454
2vesGVRUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.454
2xikJ60Serine/threonine-protein kinase 252.7.11.10.454
2yn8STUEphrin type-B receptor 42.7.10.10.454
3sdkP3NProteasome subunit beta type-53.4.25.10.454
3sdkP3NProteasome subunit beta type-63.4.25.10.454
4c61LMMTyrosine-protein kinase JAK2/0.454
4g3jVNTLanosterol 14-alpha-demethylase/0.454
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.454
4kbk1QGCasein kinase I isoform delta2.7.11.10.454
1h1s4SPCyclin-dependent kinase 22.7.11.220.453
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.453
1i7gAZ2Peroxisome proliferator-activated receptor alpha/0.453
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.453
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.453
2itqITQEpidermal growth factor receptor2.7.10.10.453
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.453
2wxvWXVCyclin-dependent kinase 22.7.11.220.453
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.453
2xa4AZ5Tyrosine-protein kinase JAK2/0.453
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.453
3pj8404Cyclin-dependent kinase 22.7.11.220.453
3w2sW2REpidermal growth factor receptor2.7.10.10.453
4ctaATPCinA-like protein/0.453
4e5yNDPGDP-L-fucose synthase1.1.1.2710.453
4hvg19QTyrosine-protein kinase JAK32.7.10.20.453
1pjkANPCasein kinase II subunit alpha2.7.11.10.452
2hcdBIVVitamin D3 receptor A/0.452
2itnANPEpidermal growth factor receptor2.7.10.10.452
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.452
3d8vUD1Bifunctional protein GlmU/0.452
4a83DXCMajor pollen allergen Bet v 1-A/0.452
4aa5NQBMitogen-activated protein kinase 14/0.452
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.452
4yuqKS1Calmodulin-like domain protein kinase/0.452
1c70L75Protease/0.451
1fvv107Cyclin-dependent kinase 22.7.11.220.451
1xddAAYIntegrin alpha-L/0.451
2b1pAIZMitogen-activated protein kinase 102.7.11.240.451
2ckeIQUDeath-associated protein kinase 2/0.451
2d8aNADL-threonine 3-dehydrogenase/0.451
2i4zDRHPeroxisome proliferator-activated receptor gamma/0.451
2igoFADPyranose 2-oxidase/0.451
2izsBRQCasein kinase I isoform gamma-32.7.11.10.451
2yyiFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.451
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.451
3h86AP5Adenylate kinase/0.451
3keuATPPyridoxal kinase2.7.1.350.451
3t4nADP5'-AMP-activated protein kinase subunit gamma/0.451
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.451
3vs3VSETyrosine-protein kinase HCK2.7.10.20.451
4loqSB4Mitogen-activated protein kinase 14/0.451
4oauADP2-5A-dependent ribonuclease3.1.260.451
4xiwAZMCarbonic anhydrase, alpha type/0.451
1i59ANPChemotaxis protein CheA2.7.13.30.450
2uxoTACHTH-type transcriptional regulator TtgR/0.450
3gep24HHypoxanthine-guanine phosphoribosyltransferase2.4.2.80.450
3hvcGG5Mitogen-activated protein kinase 14/0.450
3mk6ACOPantothenate kinase 32.7.1.330.450
3vryB43Tyrosine-protein kinase HCK2.7.10.20.450
4a99FADTetX family tetracycline inactivation enzyme/0.450
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.450
4g7gVFVLanosterol 14-alpha-demethylase/0.450
4nks2M2Fibroblast growth factor receptor 1/0.450
4qmzB49Serine/threonine-protein kinase 242.7.11.10.450
1qpePP2Tyrosine-protein kinase Lck2.7.10.20.449
1u54ACPActivated CDC42 kinase 1/0.449
2c0iL1GTyrosine-protein kinase HCK2.7.10.20.449
2zdt46CMitogen-activated protein kinase 102.7.11.240.449
3mvl38PMitogen-activated protein kinase 14/0.449
4a6cQG9Gag-Pol polyprotein3.4.23.160.449
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.449
4c58824Cyclin-G-associated kinase2.7.11.10.449
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.449
4ia1BIVVitamin D3 receptor A/0.449
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.448
2npaMMBPeroxisome proliferator-activated receptor alpha/0.448
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.448
2xviFADPutative flavin-containing monooxygenase/0.448
3gfbNADL-threonine 3-dehydrogenase/0.448
3tz3B36Acetyl-CoA carboxylase/0.448
3wmxNADNAD dependent epimerase/dehydratase/0.448
4kioG5KTyrosine-protein kinase ITK/TSK2.7.10.20.448
4nwzFADFAD-dependent pyridine nucleotide-disulfide oxidoreductase/0.448
1k7l544Peroxisome proliferator-activated receptor alpha/0.447
1lluNADAlcohol dehydrogenase/0.447
2c0tL3GTyrosine-protein kinase HCK2.7.10.20.447
2hasC3OVitamin D3 receptor/0.447
2i40BLZCyclin-dependent kinase 22.7.11.220.447
2pmlANPUncharacterized protein/0.447
2qo9ANPEphrin type-A receptor 32.7.10.10.447
2uxpCLMHTH-type transcriptional regulator TtgR/0.447
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.447
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.447
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.447
3inmNDPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.447
3pvwQRXBeta-adrenergic receptor kinase 12.7.11.150.447
3ttjJBIMitogen-activated protein kinase 102.7.11.240.447
3vs1VSATyrosine-protein kinase HCK2.7.10.20.447
4aa4QC0Mitogen-activated protein kinase 14/0.447
4e4m0NHTyrosine-protein kinase JAK2/0.447
4f7iNAD3-isopropylmalate dehydrogenase1.1.1.850.447
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4jqlVJ6Heat shock protein HSP 90-alpha/0.447
4l7f1V5Mitogen-activated protein kinase 82.7.11.240.447
1nooCAHCamphor 5-monooxygenase1.14.15.10.446
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.446
2e9dB76Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.446
2xrwANPMitogen-activated protein kinase 82.7.11.240.446
3ddpRC8Cyclin-dependent kinase 22.7.11.220.446
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.446
3kf7L9GMitogen-activated protein kinase 14/0.446
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.446
3ogqAB1Pol polyprotein/0.446
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.446
4fg8ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.446
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.446
5a27MYAGlycylpeptide N-tetradecanoyltransferase/0.446
1t86CAMCamphor 5-monooxygenase1.14.15.10.445
1y0s331Peroxisome proliferator-activated receptor delta/0.445
2balPQAMitogen-activated protein kinase 14/0.445
2bfyH1NAurora kinase B-A2.7.11.10.445
2yylFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.445
2znq401Peroxisome proliferator-activated receptor delta/0.445
3p3zP3ZPutative cytochrome P450/0.445
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.445
1gqtACPRibokinase/0.444
1m13HYFNuclear receptor subfamily 1 group I member 2/0.444
1w6hTITPlasmepsin-23.4.23.390.444
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.444
2fumMIXSerine/threonine-protein kinase PknB2.7.11.10.444
2j0lANPFocal adhesion kinase 12.7.10.20.444
2j4z626Aurora kinase A2.7.11.10.444
2xneASHAurora kinase A2.7.11.10.444
3c50ADPRhodopsin kinase/0.444
3mdvCL6Cholesterol 24-hydroxylase/0.444
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.444
4c57FEFCyclin-G-associated kinase2.7.11.10.444
4enhFVXCholesterol 24-hydroxylase/0.444
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.444
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.444
4v12POGMaoC like domain protein/0.444
1nhhANPDNA mismatch repair protein MutL/0.443
1ppm0P1Penicillopepsin-13.4.23.200.443
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.443
2jn3JN3Fatty acid-binding protein, liver/0.443
2lbaCHOFatty acid binding protein 6/0.443
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.443
2po7CHDFerrochelatase, mitochondrial4.99.1.10.443
2wihP48Cyclin-dependent kinase 22.7.11.220.443
2xj2985Serine/threonine-protein kinase pim-12.7.11.10.443
2zbaZBATrichothecene 3-O-acetyltransferase/0.443
3bhtMFRCyclin-dependent kinase 22.7.11.220.443
3dogNNNCyclin-dependent kinase 22.7.11.220.443
3oibFDAPutative acyl-CoA dehydrogenase/0.443
4a32MYAGlycylpeptide N-tetradecanoyltransferase/0.443
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.443
4dgnLU2Casein kinase II subunit alpha2.7.11.10.443
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4fob0USALK tyrosine kinase receptor2.7.10.10.443
4kb81QNCasein kinase I isoform delta2.7.11.10.443
4qi4FADCellobiose dehydrogenase/0.443
4ux9ANPMitogen-activated protein kinase 82.7.11.240.443
1fxsNAPGDP-L-fucose synthase/0.442
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.442
2cy0NAPShikimate dehydrogenase (NADP(+))/0.442
2excJNKMitogen-activated protein kinase 102.7.11.240.442
2qo5CHDFatty acid-binding protein 10-A, liver basic/0.442
3a62STURibosomal protein S6 kinase beta-12.7.11.10.442
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.442
3zm422TDual specificity mitogen-activated protein kinase kinase 12.7.12.20.442
3zuxTCHTransporter/0.442
4fz60VGTyrosine-protein kinase SYK2.7.10.20.442
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.442
1eh4IC1Casein kinase I homolog 12.7.11.10.441
1hdrNADDihydropteridine reductase1.5.1.340.441
1xjdSTUProtein kinase C theta type2.7.11.130.441
2qocANPEphrin type-A receptor 32.7.10.10.441
3flzFLZMitogen-activated protein kinase 14/0.441
3oriAGSSerine/threonine protein kinase/0.441
3tqhNDPQuinone oxidoreductase/0.441
3vt65YIVitamin D3 receptor/0.441
3wrmCAMCamphor 5-monooxygenase1.14.15.10.441
4q72FADBifunctional protein PutA/0.441
4q73FADBifunctional protein PutA/0.441
4qmySTUSerine/threonine-protein kinase 242.7.11.10.441
1bsvNDPGDP-L-fucose synthase/0.440
1gteFADDihydropyrimidine dehydrogenase [NADP(+)]1.3.1.20.440
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.440
1ir3ANPInsulin receptor2.7.10.10.440
3bu5ATPInsulin receptor2.7.10.10.440
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.440
3i59N6SCRP-like cAMP-activated global transcriptional regulator/0.440
3lfqA28Cyclin-dependent kinase 22.7.11.220.440
3qyw6PBMitogen-activated protein kinase 12.7.11.240.440
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.440
3sufSUEPolyprotein/0.440
3vrwYS5Vitamin D3 receptor/0.440
4a33MYAGlycylpeptide N-tetradecanoyltransferase/0.440
4a8v2ANMajor pollen allergen Bet v 1-J/0.440
4aqc88ATyrosine-protein kinase JAK2/0.440
4c4jX21Dual specificity protein kinase TTK2.7.12.10.440
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.440
4nr42LKCREB-binding protein/0.440
4r21STRCytochrome P450 family 17 polypeptide 2/0.440