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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4c35NU3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.11

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
4c35NU3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.111.000
4c36ZO9cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.575
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.554
3cqwCQWRAC-alpha serine/threonine-protein kinase2.7.11.10.537
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.537
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.536
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.534
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.533
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.533
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.529
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.528
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.527
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.527
1q8uH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.523
3kkvB99cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.522
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.521
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.519
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.518
1zys199Serine/threonine-protein kinase Chk12.7.11.10.518
3l9nL9NcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.516
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.516
1ydrIQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.515
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.515
4ful0VUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.514
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.512
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.511
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.511
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.510
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.509
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.509
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.509
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.509
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.508
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.508
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.507
2izrBRKCasein kinase I isoform gamma-32.7.11.10.506
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.506
4fad0TBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.504
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.502
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.501
2hog710Serine/threonine-protein kinase Chk12.7.11.10.501
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.501
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.501
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.499
4ft3H1KSerine/threonine-protein kinase Chk12.7.11.10.497
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.495
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.494
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.492
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.492
4ftlH0KSerine/threonine-protein kinase Chk12.7.11.10.491
1zltHYMSerine/threonine-protein kinase Chk12.7.11.10.490
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.490
3oogYTPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.490
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.488
4fhj0TZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.488
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.487
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.487
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.487
1tqpATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.486
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.486
2wpa889Cyclin-dependent kinase 22.7.11.220.486
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.485
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.485
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.485
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.485
4fa60TAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.484
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.484
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.484
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.483
3ncz3NCRho-associated protein kinase 12.7.11.10.483
1q8wM77cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.482
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.481
3pe2E1BCasein kinase II subunit alpha2.7.11.10.481
3zo1SIJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.481
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.480
3gu7ADPDeath-associated protein kinase 12.7.11.10.480
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.480
2f2uM77Rho-associated protein kinase 22.7.11.10.479
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.479
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.479
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.479
4dymIYZActivin receptor type-12.7.11.300.479
2bkzSBCCyclin-dependent kinase 22.7.11.220.478
3imgBZ2Pantothenate synthetase6.3.2.10.478
4bgg844Activin receptor type-12.7.11.300.478
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.478
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.478
2xikJ60Serine/threonine-protein kinase 252.7.11.10.477
4otiMI1Serine/threonine-protein kinase N1/0.477
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.476
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.476
3lq4TDPPyruvate dehydrogenase E1 component1.2.4.10.476
3a62STURibosomal protein S6 kinase beta-12.7.11.10.475
4ekl0RFRAC-alpha serine/threonine-protein kinase2.7.11.10.475
4iarERM5-hydroxytryptamine receptor 1B/0.475
1k7fIAVTryptophan synthase alpha chain/0.474
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.474
3tea4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.474
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.473
1oiyN41Cyclin-dependent kinase 22.7.11.220.473
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.473
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.473
4g160VMCasein kinase I isoform gamma-32.7.11.10.473
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.472
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.472
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.472
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.472
2cchATPCyclin-dependent kinase 22.7.11.220.471
2ckeIQUDeath-associated protein kinase 2/0.471
2e9p77ASerine/threonine-protein kinase Chk12.7.11.10.471
2pmnK51Protein kinase 7/0.471
3imeBZ2Pantothenate synthetase6.3.2.10.471
3q43D66M1 family aminopeptidase3.4.110.471
3rvhHQ2Lysine-specific demethylase 4A1.14.110.471
3umw596Serine/threonine-protein kinase pim-12.7.11.10.471
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.470
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.470
1e9hINRCyclin-dependent kinase 22.7.11.220.470
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.470
1q4l679Glycogen synthase kinase-3 beta2.7.11.260.470
4g3pUD1Bifunctional protein GlmU/0.470
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.469
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.469
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.469
3bqr4RBDeath-associated protein kinase 3/0.469
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.469
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.469
3mtfA3FActivin receptor type-12.7.11.300.469
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.469
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.469
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.469
4h9814QUncharacterized protein/0.469
3c35KAIGlutamate receptor ionotropic, kainate 1/0.468
3m42HGFMAP kinase-activated protein kinase 22.7.11.10.468
3qarQARPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.468
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.468
5auwQUEDeath-associated protein kinase 12.7.11.10.468
2etrY27Rho-associated protein kinase 12.7.11.10.467
3elySAHMethyltransferase/0.467
3mb714ICasein kinase II subunit alpha2.7.11.10.467
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.467
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.467
1e8wQUEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.466
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.466
2ojg19AMitogen-activated protein kinase 12.7.11.240.466
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.466
3iodA6DPantothenate synthetase6.3.2.10.466
4yuqKS1Calmodulin-like domain protein kinase/0.466
3dcv55ESerine/threonine-protein kinase pim-12.7.11.10.465
3qfvNM7Serine/threonine-protein kinase MRCK beta2.7.11.10.465
1fvv107Cyclin-dependent kinase 22.7.11.220.464
1hv9UD1Bifunctional protein GlmU/0.464
1rfuADPPyridoxal kinase2.7.1.350.464
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.464
1tqmANPRIO-type serine/threonine-protein kinase Rio22.7.11.10.464
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.464
2vuw5IDSerine/threonine-protein kinase haspin2.7.11.10.464
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.464
3gubGUBDeath-associated protein kinase 12.7.11.10.464
3nizADPCdc2-like CDK2/CDC28 like protein kinase/0.464
3tnwF18Cyclin-dependent kinase 22.7.11.220.464
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.464
4c02TAKActivin receptor type-12.7.11.300.464
4othDRNSerine/threonine-protein kinase N1/0.464
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.464
4xwtU5PRibonuclease J/0.464
2yn8STUEphrin type-B receptor 42.7.10.10.463
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.463
3pmy41LEndothiapepsin3.4.23.220.463
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.463
1q4u4CA4-hydroxybenzoyl-CoA thioesterase3.1.2.230.462
1v0oINRCell division control protein 2 homolog2.7.11.220.462
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.462
2uw4L15cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.462
2uzeC95Cyclin-dependent kinase 22.7.11.220.462
2wouZZFTGF-beta receptor type-12.7.11.300.462
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.462
3kgaLX9MAP kinase-activated protein kinase 22.7.11.10.462
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.462
4aqkADPInositol-pentakisphosphate 2-kinase2.7.1.1580.462
4eol1ROCyclin-dependent kinase 22.7.11.220.462
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.461
4fx360KCyclin-dependent kinase 22.7.11.220.461
4gmy0X5Tyrosine-protein kinase JAK2/0.461
4l435FIRibosomal protein S6 kinase beta-12.7.11.10.461
4djhJDCKappa-type opioid receptor/0.461
1ir3ANPInsulin receptor2.7.10.10.460
2etkHFSRho-associated protein kinase 12.7.11.10.460
2r3p3SCCyclin-dependent kinase 22.7.11.220.460
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.460
3dpd41APhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
3wbbNAPMeso-diaminopimelate D-dehydrogenase/0.460
4gv10XZRAC-alpha serine/threonine-protein kinase2.7.11.10.460
4mb2ATPUncharacterized protein/0.460
2vagV25Dual specificity protein kinase CLK12.7.12.10.459
2vo6M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.459
2wihP48Cyclin-dependent kinase 22.7.11.220.459
3a60STURibosomal protein S6 kinase beta-12.7.11.10.459
3bhtMFRCyclin-dependent kinase 22.7.11.220.459
3mvl38PMitogen-activated protein kinase 14/0.459
3w33W19Epidermal growth factor receptor2.7.10.10.459
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.459
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.459
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.459
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.459
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.458
2c27ACOMycothiol acetyltransferase2.3.1.1890.458
2izsBRQCasein kinase I isoform gamma-32.7.11.10.458
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
2uzbC75Cyclin-dependent kinase 22.7.11.220.458
2vo0M03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.458
3pvwQRXBeta-adrenergic receptor kinase 12.7.11.150.458
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
3r8zZ63Cyclin-dependent kinase 22.7.11.220.458
4bdbODOSerine/threonine-protein kinase Chk22.7.11.10.458
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.458
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
1zgaHMKIsoflavone 4'-O-methyltransferase/0.457
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.457
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
2g28TDKPyruvate dehydrogenase E1 component1.2.4.10.457
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.457
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.457
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.457
3sf6FDAGlutaryl-CoA dehydrogenase/0.457
4hgs15GCasein kinase I isoform gamma-32.7.11.10.457
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.457
2c5nCK8Cyclin-dependent kinase 22.7.11.220.456
2gnfY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
2j0k4STFocal adhesion kinase 12.7.10.20.456
2wmvZYVSerine/threonine-protein kinase Chk12.7.11.10.456
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.456
3lfsA07Cyclin-dependent kinase 22.7.11.220.456
3sheI85MAP kinase-activated protein kinase 32.7.11.10.456
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.456
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.456
4gvjADPNon-receptor tyrosine-protein kinase TYK22.7.10.20.456
4j1rI5RGlycogen synthase kinase-3 beta2.7.11.260.456
4jrnANPRhoptry kinase family protein/0.456
4n6z2HWSerine/threonine-protein kinase pim-12.7.11.10.456
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.455
2x1nX1NCyclin-dependent kinase 22.7.11.220.455
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
3pd2A3SThreonine--tRNA ligase6.1.1.30.455
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.455
4ewqMWLMitogen-activated protein kinase 14/0.455
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.455
5auxKMPDeath-associated protein kinase 12.7.11.10.455
5av4GENDeath-associated protein kinase 12.7.11.10.455
5c1mCLRMu-type opioid receptor/0.455
1ppm0P1Penicillopepsin-13.4.23.200.454
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.454
2oymMNIEndoglycoceramidase II/0.454
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.454
2zjwREFCasein kinase II subunit alpha2.7.11.10.454
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.454
3l08ZIGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
3r9dX6BCyclin-dependent kinase 22.7.11.220.454
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.454
4cztCPSCBL-interacting serine/threonine-protein kinase 232.7.11.10.454
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
4jik1KOSerine/threonine-protein kinase Chk12.7.11.10.454
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.454
1ykr628Cyclin-dependent kinase 22.7.11.220.453
2dwbANPAurora kinase A2.7.11.10.453
2ieaTDPPyruvate dehydrogenase E1 component1.2.4.10.453
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.453
3tkuM77Serine/threonine-protein kinase MRCK beta2.7.11.10.453
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.453
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.453
4o671SYCyclic GMP-AMP synthase/0.453
4wudANPDNA gyrase subunit B/0.453
5e8xSTUTGF-beta receptor type-12.7.11.300.453
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.10.452
1zp9ATPRIO-type serine/threonine-protein kinase Rio12.7.11.10.452
2a5uQYTPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
2gnlH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
3c36KAIGlutamate receptor ionotropic, kainate 1/0.452
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.452
3mv5XFERAC-alpha serine/threonine-protein kinase2.7.11.10.452
3nbwTR4Ketohexokinase/0.452
4bcmT7ZCyclin-dependent kinase 22.7.11.220.452
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.452
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.452
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.452
4iwd1JCHepatocyte growth factor receptor2.7.10.10.452
4z5wILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.452
5e8wSTUTGF-beta receptor type-12.7.11.300.452
3gu83GUDeath-associated protein kinase 12.7.11.10.451
3qu0X40Cyclin-dependent kinase 22.7.11.220.451
3r02UNMSerine/threonine-protein kinase pim-12.7.11.10.451
3ral04ZCyclin-dependent kinase 22.7.11.220.451
4bfvZVVPantothenate kinase2.7.1.330.451
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
5f0a1FBcGMP-dependent protein kinase, putative/0.451
1bxoPP7Penicillopepsin-13.4.23.200.450
1oi9N20Cyclin-dependent kinase 22.7.11.220.450
2iqgF2IBeta-secretase 13.4.23.460.450
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.450
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.450
3jpv1DRSerine/threonine-protein kinase pim-12.7.11.10.450
3mvhWFERAC-alpha serine/threonine-protein kinase2.7.11.10.450
3nynSGVG protein-coupled receptor kinase 62.7.11.160.450
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.450
4jrvKJVEpidermal growth factor receptor2.7.10.10.450
4olfHFGProline--tRNA ligase6.1.1.150.450
5av2KMPDeath-associated protein kinase 12.7.11.10.450
1aq1STUCyclin-dependent kinase 22.7.11.220.449
1e81M91Endothiapepsin3.4.23.220.449
1h1s4SPCyclin-dependent kinase 22.7.11.220.449
1owoFADDeoxyribodipyrimidine photo-lyase4.1.99.30.449
1q1wFADPutidaredoxin reductase1.18.1.50.449
2c5yMTWCyclin-dependent kinase 22.7.11.220.449
2gciMRRProbable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase )/0.449
2iw84SPCyclin-dependent kinase 22.7.11.220.449
2pmlANPUncharacterized protein/0.449
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.449
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.449
3qizQI2Botulinum neurotoxin type A3.4.24.690.449
3rak03ZCyclin-dependent kinase 22.7.11.220.449
4fks46KCyclin-dependent kinase 22.7.11.220.449
4hnc0UTMandelate racemase/0.449
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.449
4mwhATPCasein kinase II subunit alpha2.7.11.10.449
1mqeAPRMutT/nudix family protein/0.448
1p4fDRGDeath-associated protein kinase 12.7.11.10.448
2itqITQEpidermal growth factor receptor2.7.10.10.448
2xuuADPDeath-associated protein kinase 12.7.11.10.448
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.448
3oom507Activin receptor type-12.7.11.300.448
3qwkX62Cyclin-dependent kinase 22.7.11.220.448
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.447
1qiqACCIsopenicillin N synthase1.21.3.10.447
2btsU32Cyclin-dependent kinase 22.7.11.220.447
2yee2ECHeat shock protein HSP 90-alpha/0.447
3lpfZ77Beta-glucuronidase3.2.1.310.447
3pdqKC6Lysine-specific demethylase 4A1.14.110.447
3uwqU5POrotidine 5'-phosphate decarboxylase/0.447
4eok4SPCyclin-dependent kinase 22.7.11.220.447
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.447
4nj32KDCyclin-dependent kinase 22.7.11.220.447
5dgzL20Serine/threonine-protein kinase pim-12.7.11.10.447
4ej4EJ4Delta-type opioid receptor/0.447
1pnvTYDdTDP-epi-vancosaminyltransferase2.4.1.3110.446
2wotZZGTGF-beta receptor type-12.7.11.300.446
2xj2985Serine/threonine-protein kinase pim-12.7.11.10.446
3jy0LYGSerine/threonine-protein kinase pim-12.7.11.10.446
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.446
3sni546cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.446
3sptUD1Bifunctional protein GlmU/0.446
1foaUD1Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase2.4.1.1010.445
1h1q2A6Cyclin-dependent kinase 22.7.11.220.445
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.445
1zgyBRLPeroxisome proliferator-activated receptor gamma/0.445
2d29FADAcyl-CoA dehydrogenase/0.445
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.445
2vf0F89Thymidylate synthase/0.445
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.445
2wxvWXVCyclin-dependent kinase 22.7.11.220.445
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.445
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.445
3c4zADPRhodopsin kinase/0.445
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3mvjXFEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.445
3roy22ZCyclin-dependent kinase 22.7.11.220.445
4iaq2GM5-hydroxytryptamine receptor 1B/0.445
4qmySTUSerine/threonine-protein kinase 242.7.11.10.445
1pxlCK4Cyclin-dependent kinase 22.7.11.220.444
2c3iIYZSerine/threonine-protein kinase pim-12.7.11.10.444
2ijmADPFocal adhesion kinase 12.7.10.20.444
2j0lANPFocal adhesion kinase 12.7.10.20.444
2w6qOA5Biotin carboxylase6.3.4.140.444
2y882ERPhosphoribosyl isomerase A5.3.1.160.444
3gwfNAPCyclohexanone monooxygenase/0.444
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.444
3tm5SFGUncharacterized protein/0.444
1pyePM1Cyclin-dependent kinase 22.7.11.220.443
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
1yidATPTryptophan--tRNA ligase 26.1.1.20.443
1zrzBI1Protein kinase C iota type2.7.11.130.443
2erzHFScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
2vd5BI8Myotonin-protein kinase2.7.11.10.443
2vx07X7Ephrin type-B receptor 42.7.10.10.443
2w05FRTCyclin-dependent kinase 22.7.11.220.443
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.443
3lfqA28Cyclin-dependent kinase 22.7.11.220.443
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4iazADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.443
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.443
4uakADPSerine/threonine-protein kinase MRCK beta2.7.11.10.443
1vyw292Cyclin-dependent kinase 22.7.11.220.442
1xjdSTUProtein kinase C theta type2.7.11.130.442
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.442
2c6tDT5Cyclin-dependent kinase 22.7.11.220.442
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.442
2vrx447Aurora kinase B-A2.7.11.10.442
2vttLZDCyclin-dependent kinase 22.7.11.220.442
2yk2YJWHeat shock protein HSP 90-alpha/0.442
3ezrEZRCyclin-dependent kinase 22.7.11.220.442
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.442
3gu6ADPDeath-associated protein kinase 12.7.11.10.442
3ibeL64Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.442
3ormAGSSerine/threonine protein kinase/0.442
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
4eomATPCyclin-dependent kinase 22.7.11.220.442
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.442
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.442
4ivb1J5Tyrosine-protein kinase JAK1/0.442
4oh4ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.442
5auzGENDeath-associated protein kinase 12.7.11.10.442
1dj2GDPAdenylosuccinate synthetase, chloroplastic/0.441
1h83FADPolyamine oxidase1.5.3.140.441
1pkdUCNCyclin-dependent kinase 22.7.11.220.441
1umlFR4Adenosine deaminase3.5.4.40.441
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.441
2fvdLIACyclin-dependent kinase 22.7.11.220.441
2nnqT4BFatty acid-binding protein, adipocyte/0.441
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.441
2uzlC94Cyclin-dependent kinase 22.7.11.220.441
2vgoAD5Aurora kinase B-A2.7.11.10.441
3fnlSHALactoperoxidase/0.441
3pre3REPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
3qc9ADPRhodopsin kinase/0.441
4eoi1ROCyclin-dependent kinase 22.7.11.220.441
4fyn0VETyrosine-protein kinase SYK2.7.10.20.441
4gd40WSLysine-specific demethylase 4A1.14.110.441
4kp71UQ1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.441
4krcAGSCyclin-dependent protein kinase PHO852.7.11.220.441
4l23X6KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.441
4l9i8PRRhodopsin kinase/0.441
1dm2HMDCyclin-dependent kinase 22.7.11.220.440
1e82M90Endothiapepsin3.4.23.220.440
1snuSTUTyrosine-protein kinase ITK/TSK2.7.10.20.440
1urwI1PCyclin-dependent kinase 22.7.11.220.440
1vjy460TGF-beta receptor type-12.7.11.300.440
2bhhRYUCyclin-dependent kinase 22.7.11.220.440
2i0y5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.440
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.440
2p83MR0Beta-secretase 13.4.23.460.440
3buzLARActin, alpha skeletal muscle/0.440
3c50ADPRhodopsin kinase/0.440
3kc3MK2MAP kinase-activated protein kinase 22.7.11.10.440
3q44D50M1 family aminopeptidase3.4.110.440
3q9wEMOCasein kinase II subunit alpha2.7.11.10.440
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.440
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.440
4rrxLURProstaglandin G/H synthase 21.14.99.10.440
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.440