scPDB - Distribution of Binding site Similarity values of 4bzc entry / Site 11

Distribution of Binding site similarity measured by Shaper

You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4bzc	T8T	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	3.1.5

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
4bzc	T8T	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	3.1.5	1.000
4tny	DTP	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	3.1.5	0.593
4qfy	DGT	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	3.1.5	0.570
4to6	DTP	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	3.1.5	0.569
4qfx	DTP	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	3.1.5	0.504