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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4buuF38Tankyrase-22.4.2.30

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4buuF38Tankyrase-22.4.2.301.000
4l0s1UZTankyrase-22.4.2.300.864
4bu908CTankyrase-22.4.2.300.853
4but31FTankyrase-22.4.2.300.853
4hlk431Tankyrase-22.4.2.300.762
4buiW2ETankyrase-22.4.2.300.751
5aku29FTankyrase-22.4.2.300.717
4l2f1V3Tankyrase-22.4.2.300.697
4kzl20DTankyrase-22.4.2.300.691
4hlg20BTankyrase-22.4.2.300.647
4avwG18Tankyrase-22.4.2.300.646
4l0i1UWTankyrase-22.4.2.300.636
4l31F08Tankyrase-22.4.2.300.629
4l33F70Tankyrase-22.4.2.300.629
4l0v1V1Tankyrase-22.4.2.300.628
3kr8XAVTankyrase-22.4.2.300.627
4bueJQFTankyrase-22.4.2.300.627
4l10A63Tankyrase-22.4.2.300.625
4l341VGTankyrase-22.4.2.300.624
4hkiFLNTankyrase-22.4.2.300.623
4bufF36Tankyrase-22.4.2.300.622
4kzuA73Tankyrase-22.4.2.300.621
4l2g1V4Tankyrase-22.4.2.300.613
4hlh20DTankyrase-22.4.2.300.610
4l2k1V8Tankyrase-22.4.2.300.610
4hlf15ZTankyrase-22.4.2.300.608
4bud29FTankyrase-22.4.2.300.606
4l0t1V0Tankyrase-22.4.2.300.606
4hkkAGITankyrase-22.4.2.300.599
4l321VFTankyrase-22.4.2.300.599
4buxF35Tankyrase-22.4.2.300.597
4hknLU2Tankyrase-22.4.2.300.597
4bus32FTankyrase-22.4.2.300.596
4hl515WTankyrase-22.4.2.300.590
4j21AJ6Tankyrase-22.4.2.300.586
4j22AJ7Tankyrase-22.4.2.300.580
4iueAJ4Tankyrase-22.4.2.300.573
4hlm16STankyrase-22.4.2.300.570
3p0pNNFTankyrase-22.4.2.300.568
4buwF33Tankyrase-22.4.2.300.559
4hmhF94Tankyrase-22.4.2.300.556
4buv16ITankyrase-22.4.2.300.555
4bs4A64Tankyrase-22.4.2.300.549
4krs1SXTankyrase-12.4.2.300.525
4msk2C8Tankyrase-12.4.2.300.512
4pnrG18Tankyrase-22.4.2.300.499
4bjbP34Tankyrase-22.4.2.300.487
4l091URTankyrase-22.4.2.300.479
3a1l2CCCytochrome P450/0.452
4j3lAJ5Tankyrase-22.4.2.300.450
4j3mAJ8Tankyrase-22.4.2.300.447
1x8lOXRRetinol dehydratase/0.442
4hhz15SPoly [ADP-ribose] polymerase 12.4.2.300.442