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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4bgq38RCyclin-dependent kinase-like 52.7.11.22

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4bgq38RCyclin-dependent kinase-like 52.7.11.221.000
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.468
4bchT7ZCyclin-dependent kinase 92.7.11.220.467
3rak03ZCyclin-dependent kinase 22.7.11.220.459
3r9dX6BCyclin-dependent kinase 22.7.11.220.453
2vu3LZECyclin-dependent kinase 22.7.11.220.449
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.448
3zdu38RCyclin-dependent kinase-like 32.7.11.220.441