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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4bcsBTNAvidin-related protein 4/5

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4bcsBTNAvidin-related protein 4/5/1.000
2fhnBNIAvidin-related protein 4/5/0.591
1y52BTNAvidin-related protein 4/5/0.574
2fhlBNIAvidin-related protein 4/5/0.566
1avdBTNAvidin/0.526
4bx7B4FStreptavidin/0.525
2uywBTNAvd protein/0.519
2izfBTNStreptavidin/0.500
1stpBTNStreptavidin/0.494
2izlIMIStreptavidin/0.493
2aviBTNAvidin/0.492
4dneDTBStreptavidin/0.492
1sreHABStreptavidin/0.489
1srfMTBStreptavidin/0.488
2izhBTNStreptavidin/0.488
3ry2BTNStreptavidin/0.487
1srgMHBStreptavidin/0.484
2rtoIMIStreptavidin/0.483
2rtqIMIStreptavidin/0.480
2uz2BTNAvd protein/0.478
1rxhBNIStreptavidin/0.475
2rtfBTNStreptavidin/0.475
1sriDMBStreptavidin/0.473
2izgBTNStreptavidin/0.472
2rtgBTNStreptavidin/0.471
4gdaBTNStreptavidin/0.470
4z28BTNHoefavidin/0.466
1swtBTNStreptavidin/0.465
2rteBTNStreptavidin/0.465
1i9hBNIStreptavidin/0.463
1mk5BTNStreptavidin/0.463
2c4iBTNAvidin/0.456
1pq944BOxysterols receptor LXR-beta/0.455
1lcwSHMStreptavidin/0.449
2ftoCB3Thymidylate synthase/0.449
2rtiGLLStreptavidin/0.448
1lczBH7Streptavidin/0.447
1x8lOXRRetinol dehydratase/0.447
2rtdBTNStreptavidin/0.447
1df8BTNStreptavidin/0.446
2rtnIMIStreptavidin/0.446
3wyqBTNStreptavidin/0.446
2y3fBTNStreptavidin/0.444
3jpuTY4Transcriptional activator protein LasR/0.444
2zscBTNTamavidin2/0.442
4fqsLYAThymidylate synthase ThyA/0.441
1swnBTNStreptavidin/0.440
2e94364Geranylgeranyl pyrophosphate synthase/0.440
2xveFADPutative flavin-containing monooxygenase/0.440
2zatNAPDehydrogenase/reductase SDR family member 41.1.1.1840.440
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440