scPDB - Distribution of Binding site Similarity values of 4b8m entry / Site 2

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4b8m	VX6	Aurora kinase B-A	2.7.11.1

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
4b8m	VX6	Aurora kinase B-A	2.7.11.1	1.000
3e5a	VX6	Aurora kinase A	2.7.11.1	0.547
4af3	VX6	Aurora kinase B	2.7.11.1	0.448