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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4b63FADL-ornithine N(5)-monooxygenase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
4b63FADL-ornithine N(5)-monooxygenase/1.000
4b64FADL-ornithine N(5)-monooxygenase/0.718
4b65FADL-ornithine N(5)-monooxygenase/0.664
4b68FADL-ornithine N(5)-monooxygenase/0.635
5ckuFADL-ornithine N(5)-monooxygenase/0.634
4nzhFADL-ornithine N(5)-monooxygenase/0.614
4b66FADL-ornithine N(5)-monooxygenase/0.604
3s5wFADL-ornithine N(5)-monooxygenase/0.563
4b67FADL-ornithine N(5)-monooxygenase/0.550
4tm1FDAKtzI/0.550
4tm4FDAKtzI/0.548
4tlzFADKtzI/0.539
4tlxFDAKtzI/0.529
4tm3FADKtzI/0.492