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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4axaRKDcAMP-dependent protein kinase catalytic subunit alpha2.7.11.11

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4axaRKDcAMP-dependent protein kinase catalytic subunit alpha2.7.11.111.000
2vo6M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.605
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.592
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.586
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.577
3zo4QWIcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.576
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.572
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.567
1xh5R68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.558
1svgI04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.555
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.555
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.552
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.552
2vo3M04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.550
1xh6R94cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.545
1sveI01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.543
3ow3SMYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.543
3vqhIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.543
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.541
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.540
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.536
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.535
1xh7R96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.533
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.533
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.532
2uw7GVPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.531
1xhaR68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.524
1rejB1LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.522
2vo0M03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.518
1vebI05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.517
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.514
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.512
2f7z6EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.510
2uw5GVNcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.510
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.509
2gnhH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.509
1xh8R55cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.504
1svhI08cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.503
3e8cG96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.501
1xh9R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.499
1bx6BA1cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.498
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.498
3bwjARXcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.497
4ysjADPCalmodulin-like domain protein kinase/0.484
1jbpADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.483
1xh4R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.483
3aglA03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.480
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.477
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.475
4iacACPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.474
3x2wATPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.469
1q8wM77cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.466
1q8uH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.465
1tj1FADBifunctional protein PutA1.5.5.20.464
4qnyANPMitogen activated protein kinase, putative/0.461
1tj2FADBifunctional protein PutA1.5.5.20.458
3zo1SIJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
4oh4ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.458
2gnfY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
4o8aFADBifunctional protein PutA1.2.1.880.453
2fznFADBifunctional protein PutA1.5.5.20.452
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4xw4ANPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
1ydrIQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
3v5w8PRBeta-adrenergic receptor kinase 12.7.11.150.448
3idbANPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
4fv6E57Mitogen-activated protein kinase 12.7.11.240.446
4gv10XZRAC-alpha serine/threonine-protein kinase2.7.11.10.445
4l7f1V5Mitogen-activated protein kinase 82.7.11.240.443
4y93746Tyrosine-protein kinase/0.443
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.442
1tj0FADBifunctional protein PutA1.5.5.20.441
4mk029XBeta-adrenergic receptor kinase 12.7.11.150.440