Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4awtFMNNADH:flavin oxidoreductase Sye1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4awtFMNNADH:flavin oxidoreductase Sye1/1.000
2gqaFMNNADH:flavin oxidoreductase Sye1/0.787
2gouFMNNADH:flavin oxidoreductase Sye1/0.649
4awsFMNNADH:flavin oxidoreductase Sye1/0.626
4tmbFMNOld yellow enzyme/0.543
1vjiFMN12-oxophytodienoate reductase 11.3.1.420.541
1h50FMNPentaerythritol tetranitrate reductase/0.534
1h63FMNPentaerythritol tetranitrate reductase/0.531
1icsFMN12-oxophytodienoate reductase 11.3.1.420.530
4b5nFMNNAD(P)H:flavin oxidoreductase Sye4/0.518
3hgrFMN12-oxophytodienoate reductase 11.3.1.420.516
3p8iFMNPentaerythritol tetranitrate reductase/0.513
4a3uFMNNADH:flavin oxidoreductase/NADH oxidase/0.513
2q3oFMN12-oxophytodienoate reductase 31.3.1.420.512
4jicFMNGTN Reductase/0.512
3f03FMNPentaerythritol tetranitrate reductase/0.509
1icqFMN12-oxophytodienoate reductase 11.3.1.420.506
4rnvFMNNADPH dehydrogenase 11.6.99.10.505
3p84FMNPentaerythritol tetranitrate reductase/0.504
2hs8FMN12-oxophytodienoate reductase 31.3.1.420.501
3tjlFMNNADPH dehydrogenase/0.498
1icpFMN12-oxophytodienoate reductase 11.3.1.420.495
3p82FMNPentaerythritol tetranitrate reductase/0.492
3hgoFMN12-oxophytodienoate reductase 31.3.1.420.487
3p8jFMNPentaerythritol tetranitrate reductase/0.487
4m5pFMNNADPH dehydrogenase/0.487
1bwlFMNNADPH dehydrogenase 11.6.99.10.486
3hgsFMN12-oxophytodienoate reductase 31.3.1.420.484
2abbFMNPentaerythritol tetranitrate reductase/0.479
3p74FMNPentaerythritol tetranitrate reductase/0.479
4e2dFMNDehydrogenase/0.478
4df2FMNNADPH dehydrogenase/0.475
3gkaFMNN-ethylmaleimide reductase/0.470
4h6kFMNNADPH dehydrogenase 11.6.99.10.470
1vyrFMNPentaerythritol tetranitrate reductase/0.468
3l5lFMNXenobiotic reductase/0.465
3n19FNRXenobiotic reductase/0.465
2q3rFMN12-oxophytodienoate reductase 11.3.1.420.463
4rnuFMNNADPH dehydrogenase 11.6.99.10.463
1q45FMN12-oxophytodienoate reductase 31.3.1.420.462
3p62FMNPentaerythritol tetranitrate reductase/0.456
3atzFMNProstaglandin F2a synthase/0.455
4qaiFMNNADPH dehydrogenase/0.453
4utlFNRXenobiotic reductase/0.451
3p67FMNPentaerythritol tetranitrate reductase/0.450
4rnwFMNNADPH dehydrogenase 11.6.99.10.450
1h51FMNPentaerythritol tetranitrate reductase/0.447
4k7yFMNNADPH dehydrogenase 11.6.99.10.447
4rnxFMNNADPH dehydrogenase 11.6.99.10.447
4tmcFMNOld yellow enzyme/0.446
1oycFMNNADPH dehydrogenase 11.6.99.10.441
1k02FMNNADPH dehydrogenase 11.6.99.10.440