sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4at9 | UTP | Interleukin enhancer-binding factor 2 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4at9 | UTP | Interleukin enhancer-binding factor 2 | / | 1.000 | |
| 4at8 | ATP | Interleukin enhancer-binding factor 2 | / | 0.554 | |
| 2aaz | CB3 | Thymidylate synthase | 2.1.1.45 | 0.463 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.452 | |
| 2qfx | NDP | Isocitrate dehydrogenase [NADP], mitochondrial | 1.1.1.42 | 0.447 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.447 | |
| 5ify | UMP | Glucose-1-phosphate thymidylyltransferase | / | 0.447 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.442 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.442 | |
| 1t0l | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.440 | |
| 3baz | NAP | Hydroxyphenylpyruvate reductase | 1.1.1.237 | 0.440 | |
| 4kzo | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.440 | |
| 5ag6 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 |