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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4ap7F47Hepatocyte growth factor receptor2.7.10.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4ap7F47Hepatocyte growth factor receptor2.7.10.11.000
3zxzKRWHepatocyte growth factor receptor2.7.10.10.617
3zze6XPHepatocyte growth factor receptor2.7.10.10.611
4deg0JJHepatocyte growth factor receptor2.7.10.10.593
4gg70J8Hepatocyte growth factor receptor2.7.10.10.587
2wgjVGHHepatocyte growth factor receptor2.7.10.10.572
4gg50J3Hepatocyte growth factor receptor2.7.10.10.553
4aoi4K0Hepatocyte growth factor receptor2.7.10.10.525
3zc5W9ZHepatocyte growth factor receptor2.7.10.10.523
3a4pDFQHepatocyte growth factor receptor2.7.10.10.518
1u54ACPActivated CDC42 kinase 1/0.459
3zbx6XEHepatocyte growth factor receptor2.7.10.10.458
1u2gAPRNAD(P) transhydrogenase subunit alpha part 11.6.1.20.452
3vetADPnebramycin 5' synthase6.1.2.20.452
2wkmPFYHepatocyte growth factor receptor2.7.10.10.451
2fwzH71Heat shock protein HSP 90-alpha/0.448
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.447
3v0p4GWHisto-blood group ABO system transferase/0.447
3s1dZIRCytokinin dehydrogenase 11.5.99.120.445
1rfvADPPyridoxal kinase2.7.1.350.444