Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4alxIZNAcetylcholine-binding protein

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4alxIZNAcetylcholine-binding protein/1.000
3u8n09SAcetylcholine-binding protein/0.496
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.490
3u8k09PAcetylcholine-binding protein/0.489
3wtkTH4Acetylcholine-binding protein/0.486
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.478
3zdhXRSAcetylcholine-binding protein/0.478
4du82P0Mevalonate diphosphate decarboxylase/0.478
3gobHXXDdmC/0.470
3zdgXRXAcetylcholine-binding protein/0.469
1r2jFADFkbI/0.467
3wthIM4Acetylcholine-binding protein/0.465
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.461
3wtiCT4Acetylcholine-binding protein/0.459
4bbyFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.457
2lbaCHOFatty acid binding protein 6/0.456
2uxpCLMHTH-type transcriptional regulator TtgR/0.455
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.454
2xytTC9Soluble acetylcholine receptor/0.454
3ruhNADUDP-N-acetylglucosamine 4-epimerase/0.454
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.453
5bmvVLBTubulin alpha-1B chain/0.453
5bmvVLBTubulin beta chain/0.453
3u8l09QAcetylcholine-binding protein/0.452
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.451
1w6hTITPlasmepsin-23.4.23.390.450
2d29FADAcyl-CoA dehydrogenase/0.449
4esoNAPPutative oxidoreductase/0.449
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.449
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.447
3u8m09RAcetylcholine-binding protein/0.446
1bwsNDPGDP-L-fucose synthase/0.445
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.445
4oqyNDP(S)-imine reductase/0.444
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.443
3qt62P0Mevalonate diphosphate decarboxylase/0.443
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.442
3oqkS52Renin3.4.23.150.442
3v2uATPProtein GAL3/0.442
4ipw1G7Mycocyclosin synthase1.14.21.90.442
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.441
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.441
2xviFADPutative flavin-containing monooxygenase/0.440
2zjuIM4Acetylcholine-binding protein/0.440
3btjDEQHTH-type transcriptional regulator QacR/0.440