sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4afg | QMR | Achbp |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4afg | QMR | Achbp | / | 1.000 | |
| 4afh | L0B | Achbp | / | 0.564 | |
| 4b5d | SW4 | Achbp | / | 0.560 | |
| 4epq | 0RR | Poly(ADP-ribose) glycohydrolase | / | 0.514 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.503 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.503 | |
| 3zdg | XRX | Acetylcholine-binding protein | / | 0.499 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.497 | |
| 3fzn | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.497 | |
| 3u8n | 09S | Acetylcholine-binding protein | / | 0.494 | |
| 4cf6 | CBD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.494 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.491 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.489 | |
| 2vtb | FAD | Cryptochrome DASH, chloroplastic/mitochondrial | / | 0.489 | |
| 3u8k | 09P | Acetylcholine-binding protein | / | 0.488 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.487 | |
| 3m4p | 4AD | Asparaginyl-tRNA synthetase, putative | / | 0.485 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.484 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.481 | |
| 4ubv | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.481 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.478 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.478 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.476 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.476 | |
| 3wtj | TH4 | Acetylcholine-binding protein | / | 0.476 | |
| 5ifi | PRX | Acetyl-coenzyme A synthetase | / | 0.476 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.475 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.475 | |
| 4l8u | 9AZ | Serum albumin | / | 0.474 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.473 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.473 | |
| 2g26 | 3LG | Renin | 3.4.23.15 | 0.473 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.472 | |
| 3wip | ACH | Acetylcholine-binding protein | / | 0.472 | |
| 4i4z | 2NE | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.472 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.471 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.471 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.471 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.471 | |
| 1fwm | CB3 | Thymidylate synthase | / | 0.470 | |
| 1np7 | FAD | Cryptochrome DASH | / | 0.470 | |
| 3wag | TYD | Glycosyltransferase | / | 0.470 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.469 | |
| 2ok7 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.469 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.469 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.468 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.468 | |
| 4bzr | K26 | Angiotensin-converting enzyme | 3.2.1 | 0.468 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.468 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.467 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.467 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.467 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.467 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.466 | |
| 3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.466 | |
| 3ieu | GDP | GTPase Era | / | 0.466 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
| 4g2r | H1L | Probable propionyl-CoA carboxylase beta chain 6 | 6.4.1.3 | 0.466 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.466 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.465 | |
| 2zju | IM4 | Acetylcholine-binding protein | / | 0.465 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.465 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.465 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.464 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 2j4d | FAD | Cryptochrome DASH, chloroplastic/mitochondrial | / | 0.464 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.464 | |
| 3fsu | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.464 | |
| 3uov | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.464 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.464 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.463 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.463 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.463 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.463 | |
| 5cts | CMC | Citrate synthase, mitochondrial | 2.3.3.1 | 0.463 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.462 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.462 | |
| 2z78 | H86 | Geranylgeranyl pyrophosphate synthase | / | 0.462 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.461 | |
| 1opm | IYG | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.461 | |
| 1q83 | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.461 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.461 | |
| 5e8j | SAH | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.461 | |
| 1p0h | COA | Mycothiol acetyltransferase | 2.3.1.189 | 0.460 | |
| 1pow | FAD | Pyruvate oxidase | 1.2.3.3 | 0.460 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.460 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.460 | |
| 2x8h | FAD | Thioredoxin glutathione reductase | / | 0.460 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 2ylx | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.460 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.460 | |
| 5dg3 | U21 | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase | / | 0.460 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.459 | |
| 1fap | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.459 | |
| 1fap | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.459 | |
| 1h69 | ARH | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.459 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 1q6n | P90 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.459 | |
| 1uxj | NAD | Malate dehydrogenase | / | 0.459 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 2bsx | NOS | Purine nucleoside phosphorylase | / | 0.459 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.459 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.458 | |
| 1umc | TDP | 2-oxoisovalerate dehydrogenase subunit alpha | 1.2.4.4 | 0.458 | |
| 1umc | TDP | 2-oxoisovalerate dehydrogenase subunit beta | 1.2.4.4 | 0.458 | |
| 2d81 | RB3 | Poly(3-hydroxybutyrate) depolymerase | / | 0.458 | |
| 2fs4 | PZ1 | Renin | 3.4.23.15 | 0.458 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.458 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.458 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.458 | |
| 3zhu | TD8 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.458 | |
| 4b1h | AR6 | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.458 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.458 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.457 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.457 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 2z52 | H23 | Geranylgeranyl pyrophosphate synthase | / | 0.457 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.457 | |
| 3ooi | SAM | Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific | 2.1.1.43 | 0.457 | |
| 4b1j | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.457 | |
| 4ema | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.457 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.456 | |
| 1h61 | PDN | Pentaerythritol tetranitrate reductase | / | 0.456 | |
| 2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.456 | |
| 2q8s | L92 | Peroxisome proliferator-activated receptor gamma | / | 0.456 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.456 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 4i0h | 1BL | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.456 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.455 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.455 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.454 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 2yye | APC | Selenide, water dikinase | 2.7.9.3 | 0.454 | |
| 3af2 | ACP | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 4da0 | GNG | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.454 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.454 | |
| 4i42 | 1HA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.454 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.454 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.453 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.453 | |
| 1nmk | SFM | Peptidyl-prolyl cis-trans isomerase A | 5.2.1.8 | 0.453 | |
| 1sq5 | ADP | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 1u1i | NAD | Myo-inositol-1-phosphate synthase (Ino1) | / | 0.453 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.453 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.453 | |
| 2wb2 | FAD | RE11660p | / | 0.453 | |
| 2y66 | N04 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.453 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.453 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 4h80 | 04T | Aldehyde dehydrogenase, dimeric NADP-preferring | / | 0.453 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.453 | |
| 4wri | OKA | Okadaic acid binding protein 2-alpha | / | 0.453 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.453 | |
| 1owp | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.452 | |
| 2hu2 | NAD | C-terminal binding protein 1 | / | 0.452 | |
| 2ie0 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.452 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.452 | |
| 4dja | FAD | (6-4) photolyase | / | 0.452 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.451 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.451 | |
| 2ome | NAD | C-terminal-binding protein 2 | / | 0.451 | |
| 2vf3 | GVS | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.451 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.451 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.451 | |
| 3u8l | 09Q | Acetylcholine-binding protein | / | 0.451 | |
| 3u8m | 09R | Acetylcholine-binding protein | / | 0.451 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 4gsu | DWZ | L,D-transpeptidase 2 | 2.3.2 | 0.451 | |
| 4gyy | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.451 | |
| 4h12 | SAH | Histone-lysine N-methyltransferase SETD2 | 2.1.1.43 | 0.451 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.451 | |
| 1aa6 | MGD | Formate dehydrogenase H | 1.1.99.33 | 0.450 | |
| 1khe | GCP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.450 | |
| 1ylu | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.450 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.450 | |
| 2vjm | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.450 | |
| 3gbk | 2PQ | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.450 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.450 | |
| 4a4w | YFB | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 4eue | NAI | Trans-2-enoyl-CoA reductase [NADH] | / | 0.450 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 1cjv | FOK | Adenylate cyclase type 2 | / | 0.449 | |
| 1cjv | FOK | Adenylate cyclase type 5 | / | 0.449 | |
| 1h2b | NAJ | NAD-dependent alcohol dehydrogenase | / | 0.449 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.449 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.449 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.449 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.449 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.449 | |
| 3koy | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.449 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.449 | |
| 4um1 | 09P | Acetylcholine-binding protein | / | 0.449 | |
| 4usq | FAD | Pyridine nucleotide-disulfide oxidoreductase | / | 0.449 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.449 | |
| 5c3a | URM | Histo-blood group ABO system transferase | / | 0.449 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.449 | |
| 1b5t | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.448 | |
| 1m8k | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.448 | |
| 2fhj | H4Z | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.448 | |
| 2hpv | FMN | FMN-dependent NADH-azoreductase | 1.7 | 0.448 | |
| 2p0r | LEU_LEU_ACE_AR7 | Calpain-9 | / | 0.448 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.448 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.448 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.448 | |
| 3s7d | LEU_SER_LYS_LYS_MLZ | N-lysine methyltransferase SMYD2 | / | 0.448 | |
| 3zhs | TD6 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.448 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.448 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.448 | |
| 4rqu | NAD | Alcohol dehydrogenase class-P | / | 0.448 | |
| 2jkv | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.447 | |
| 3e2s | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.447 | |
| 3kp0 | Z98 | D-ornithine 4,5-aminomutase subunit beta | / | 0.447 | |
| 3pxv | FMN | Nitroreductase | / | 0.447 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.447 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.447 | |
| 4boe | CLR | Japanin | / | 0.447 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.447 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.447 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.446 | |
| 1tl7 | ONM | Adenylate cyclase type 2 | / | 0.446 | |
| 1tl7 | ONM | Adenylate cyclase type 5 | / | 0.446 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.446 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.446 | |
| 2a2c | ADP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.446 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 2c1z | U2F | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.446 | |
| 2fah | GDP | Phosphoenolpyruvate carboxykinase [GTP], mitochondrial | 4.1.1.32 | 0.446 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.446 | |
| 2j83 | BAT | Ulilysin | 3.4.24 | 0.446 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.446 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.446 | |
| 3ahn | 3A1 | Oligopeptidase | / | 0.446 | |
| 3eku | CY9 | Actin-5C | / | 0.446 | |
| 3muo | ZPR | Prolyl endopeptidase | / | 0.446 | |
| 3up5 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.446 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
| 4bb2 | STR | Corticosteroid-binding globulin | / | 0.446 | |
| 4fs4 | H24 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4h30 | 0ZD | Macrophage metalloelastase | 3.4.24.65 | 0.446 | |
| 5c93 | ACP | Two-component system histidine protein kinase | / | 0.446 | |
| 1mi3 | NAD | NAD(P)H-dependent D-xylose reductase | 1.1.1.307 | 0.445 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.445 | |
| 1til | ATP | Anti-sigma F factor | / | 0.445 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.445 | |
| 2cnd | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.445 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.445 | |
| 3k1w | BFX | Renin | 3.4.23.15 | 0.445 | |
| 3t88 | S0N | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.445 | |
| 4cmf | PXG | Uncharacterized protein | / | 0.445 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.445 | |
| 4ips | 1G4 | Mycocyclosin synthase | 1.14.21.9 | 0.445 | |
| 4irn | FAD | AnaB | / | 0.445 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.445 | |
| 4k9d | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.445 | |
| 5czy | SAM | Eukaryotic huntingtin interacting protein B | / | 0.445 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.444 | |
| 1qvu | PRL | HTH-type transcriptional regulator QacR | / | 0.444 | |
| 2c31 | TZD | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.444 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.444 | |
| 2hwr | DRD | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.444 | |
| 2vkm | BSD | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 2wq7 | FAD | RE11660p | / | 0.444 | |
| 2x8g | FAD | Thioredoxin glutathione reductase | / | 0.444 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.444 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3uay | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.444 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.444 | |
| 3zia | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.444 | |
| 4alx | IZN | Acetylcholine-binding protein | / | 0.444 | |
| 4d89 | BXD | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.444 | |
| 4wx2 | F6F | Tryptophan synthase alpha chain | / | 0.444 | |
| 4wx2 | F6F | Tryptophan synthase beta chain | 4.2.1.20 | 0.444 | |
| 4xg1 | LLP | Diaminopimelate decarboxylase | / | 0.444 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.444 | |
| 1xag | NAD | 3-dehydroquinate synthase | / | 0.443 | |
| 2bfq | AR6 | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.443 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.443 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.443 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.443 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 3dv5 | BAV | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.443 | |
| 3gpc | COA | Acyl-coenzyme A synthetase ACSM2A, mitochondrial | 6.2.1.2 | 0.443 | |
| 3tfy | COA | N-alpha-acetyltransferase 50 | 2.3.1 | 0.443 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.443 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.443 | |
| 4f0e | 0RU | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.443 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.443 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.443 | |
| 4ynt | FDA | Glucose oxidase, putative | / | 0.443 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.442 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.442 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.442 | |
| 2d3a | ADP | Glutamine synthetase root isozyme 3 | 6.3.1.2 | 0.442 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.442 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.442 | |
| 2x86 | ADP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.442 | |
| 3kxw | 1ZZ | Saframycin Mx1 synthetase B | / | 0.442 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.442 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 1bp0 | UMP | Thymidylate synthase | / | 0.441 | |
| 1csc | CMC | Citrate synthase, mitochondrial | 2.3.3.1 | 0.441 | |
| 1ey3 | DAK | Enoyl-CoA hydratase, mitochondrial | 4.2.1.17 | 0.441 | |
| 1nyx | DRF | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.441 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.441 | |
| 2fna | ADP | Uncharacterized protein | / | 0.441 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.441 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.441 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2y03 | 5FW | Beta-1 adrenergic receptor | / | 0.441 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.441 | |
| 3he3 | FAD | UDP-galactopyranose mutase | / | 0.441 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.441 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.441 | |
| 3uic | 09T | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.441 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.441 | |
| 4dy4 | FMN | NAD(P)H dehydrogenase (quinone) | / | 0.441 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.440 | |
| 1i7i | AZ2 | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 1piw | NAP | NADP-dependent alcohol dehydrogenase 6 | 1.1.1.2 | 0.440 | |
| 1re0 | AFB | ADP-ribosylation factor 1 | / | 0.440 | |
| 1re0 | AFB | ARF guanine-nucleotide exchange factor 1 | / | 0.440 | |
| 1tys | DHF | Thymidylate synthase | / | 0.440 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.440 | |
| 2igq | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 0.440 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.440 | |
| 2r59 | PH0 | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.440 | |
| 2rm2 | W43 | Genome polyprotein | / | 0.440 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.440 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 3jv7 | NAD | Secondary alcohol dehydrogenase | / | 0.440 | |
| 3lfm | 3DT | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.440 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3ojx | NAP | NADPH--cytochrome P450 reductase | / | 0.440 | |
| 3qfc | FAD | NADPH--cytochrome P450 reductase | / | 0.440 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.440 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.440 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4tvj | 09L | Poly [ADP-ribose] polymerase 2 | 2.4.2.30 | 0.440 | |
| 4x28 | FDA | Acyl-CoA dehydrogenase FadE26 | / | 0.440 | |
| 4x28 | FDA | Acyl-CoA dehydrogenase FadE27 | / | 0.440 | |
| 5cfp | C2E | Stimulator of interferon genes protein | / | 0.440 | |
| 5kwv | ANP | Pantothenate synthetase | / | 0.440 |