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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4a0zMLCTranscription factor FapR

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4a0zMLCTranscription factor FapR/1.000
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.463
3r354CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.462
3mdmFJZCholesterol 24-hydroxylase/0.454
1q4t4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.452
4heu15JcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.447
2cf9348Prothrombin3.4.21.50.443
1q4u4CA4-hydroxybenzoyl-CoA thioesterase3.1.2.230.442
3v94WYQPhosphodiesterase/0.440