sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4a0m | NAD | Betaine aldehyde dehydrogenase, chloroplastic | 1.2.1.8 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4a0m | NAD | Betaine aldehyde dehydrogenase, chloroplastic | 1.2.1.8 | 1.000 | |
| 4v37 | NAD | Betaine aldehyde dehydrogenase, chloroplastic | 1.2.1.8 | 0.551 | |
| 2j5n | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.528 | |
| 2bja | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.511 | |
| 1bxs | NAD | Retinal dehydrogenase 1 | 1.2.1.36 | 0.505 | |
| 3iwj | NAD | Aminoaldehyde dehydrogenase | / | 0.504 | |
| 2eii | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.499 | |
| 4wb9 | NAI | Retinal dehydrogenase 1 | 1.2.1.36 | 0.498 | |
| 1o02 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.494 | |
| 2ehq | NAP | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.493 | |
| 2j40 | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.491 | |
| 1nzx | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.490 | |
| 4pxl | NAD | Aldehyde dehydrogenase3 | / | 0.490 | |
| 3iwk | NAD | Aminoaldehyde dehydrogenase | / | 0.482 | |
| 2ehu | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.481 | |
| 4x4l | NAI | Retinal dehydrogenase 1 | 1.2.1.36 | 0.481 | |
| 4pz2 | NAD | Aldehyde dehydrogenase 2-6 | / | 0.477 | |
| 2onp | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.463 | |
| 4oe2 | NAD | 2-aminomuconate 6-semialdehyde dehydrogenase | / | 0.462 | |
| 4x2q | NAD | Retinal dehydrogenase 2 | 1.2.1.36 | 0.460 | |
| 1o01 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.457 | |
| 4fr8 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.454 | |
| 1cw3 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.452 | |
| 3n82 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.452 | |
| 1nzz | NAI | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.450 | |
| 4fqf | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.447 | |
| 1o00 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.446 | |
| 1o04 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.444 | |
| 2d4e | NAD | 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenaseiheyensis HTE831] | / | 0.443 | |
| 4pt0 | NAD | Aldehyde dehydrogenase | / | 0.441 | |
| 5eyu | NAD | Betaine-aldehyde dehydrogenase | / | 0.440 |