sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3zsr | O3N | Integrase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3zsr | O3N | Integrase | / | 1.000 | |
| 4cez | O3N | Integrase | / | 1.000 | |
| 4ceo | G0T | Integrase | / | 0.682 | |
| 4ced | 9NS | Integrase | / | 0.673 | |
| 4cgg | K5Q | Integrase | / | 0.660 | |
| 4cea | ZSW | Integrase | / | 0.648 | |
| 3zt0 | ZT0 | Integrase | / | 0.646 | |
| 4cf8 | V7H | Integrase | / | 0.641 | |
| 4ceq | QCH | Integrase | / | 0.635 | |
| 3zsv | ZSV | Integrase | / | 0.630 | |
| 4ceb | ZSV | Integrase | / | 0.630 | |
| 4cfb | OM3 | Integrase | / | 0.626 | |
| 3zsw | ZSW | Integrase | / | 0.625 | |
| 4cjr | FYM | Integrase | / | 0.625 | |
| 4cig | X0P | Integrase | / | 0.622 | |
| 4ce9 | O3N | Integrase | / | 0.617 | |
| 4cer | VL4 | Integrase | / | 0.615 | |
| 4cif | JDX | Integrase | / | 0.602 | |
| 4cfa | WOP | Integrase | / | 0.600 | |
| 3zsq | O4N | Integrase | / | 0.598 | |
| 4cfc | 7NV | Integrase | / | 0.598 | |
| 4cj3 | E4F | Integrase | / | 0.597 | |
| 4cgj | NZL | Integrase | / | 0.596 | |
| 4cgd | 8P3 | Integrase | / | 0.593 | |
| 4ck1 | OM1 | Integrase | / | 0.593 | |
| 4cef | D0T | Integrase | / | 0.590 | |
| 3zsy | OM3 | Integrase | / | 0.589 | |
| 4cjf | RVN | Integrase | / | 0.588 | |
| 4cgh | LOZ | Integrase | / | 0.587 | |
| 4cje | Q31 | Integrase | / | 0.584 | |
| 4cju | JNS | Integrase | / | 0.581 | |
| 4cjs | L0Y | Integrase | / | 0.580 | |
| 4cgi | NZL | Integrase | / | 0.578 | |
| 4ck2 | NVU | Integrase | / | 0.577 | |
| 4cf0 | O5U | Integrase | / | 0.576 | |
| 4cf2 | 3GM | Integrase | / | 0.575 | |
| 4cjp | 4D2 | Integrase | / | 0.572 | |
| 4cjq | VXO | Integrase | / | 0.570 | |
| 4cee | B0T | Integrase | / | 0.566 | |
| 3zcm | PX3 | Integrase | / | 0.564 | |
| 4cec | 2SS | Integrase | / | 0.563 | |
| 4cjk | H39 | Integrase | / | 0.563 | |
| 4cfd | S8Y | Integrase | / | 0.561 | |
| 4chy | C5Q | Integrase | / | 0.560 | |
| 3zsz | OM2 | Integrase | / | 0.555 | |
| 4cf1 | IY7 | Integrase | / | 0.554 | |
| 3zt2 | ZT2 | Integrase | / | 0.547 | |
| 4cie | Y7N | Integrase | / | 0.546 | |
| 3zt3 | ZT4 | Integrase | / | 0.545 | |
| 4ck3 | K1T | Integrase | / | 0.544 | |
| 4ces | NFW | Integrase | / | 0.543 | |
| 4cj5 | 4VW | Integrase | / | 0.542 | |
| 3zsx | N44 | Integrase | / | 0.533 | |
| 4chq | CWU | Integrase | / | 0.525 | |
| 4cj4 | S3G | Integrase | / | 0.523 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.499 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.496 | |
| 3zt1 | OM1 | Integrase | / | 0.495 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.493 | |
| 3ids | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.492 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.490 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.485 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.482 | |
| 4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.482 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.478 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.478 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 1nqo | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.477 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.476 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.476 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.472 | |
| 1nq5 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.471 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.469 | |
| 3cps | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.469 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.468 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.468 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.468 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.467 | |
| 4aqc | 88A | Tyrosine-protein kinase JAK2 | / | 0.467 | |
| 2wxv | WXV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.466 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.466 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.466 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.466 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.465 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.465 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.465 | |
| 5f8e | SAH | Possible transcriptional regulatory protein | / | 0.465 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.464 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.464 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.464 | |
| 2vz6 | FEF | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.7.11.17 | 0.464 | |
| 4p8r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.464 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.463 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.463 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.462 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.462 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.462 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.462 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.461 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.461 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.460 | |
| 3fr8 | NDP | Ketol-acid reductoisomerase, chloroplastic | 1.1.1.86 | 0.460 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.459 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.459 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.459 | |
| 1pow | FAD | Pyruvate oxidase | 1.2.3.3 | 0.459 | |
| 1ppj | ANY | Cytochrome b | / | 0.459 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.459 | |
| 3dog | NNN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 4fv6 | E57 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.459 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.459 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.459 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.458 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.458 | |
| 3tw6 | ADP | Pyruvate carboxylase | / | 0.458 | |
| 3vfa | 031 | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 4ez3 | 0S0 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 4h1m | 0YJ | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.458 | |
| 4hxy | NDP | Plm1 | / | 0.458 | |
| 2gnh | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.457 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.457 | |
| 4mdh | NAD | Malate dehydrogenase, cytoplasmic | 1.1.1.37 | 0.457 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.456 | |
| 2ohv | NHL | Glutamate racemase | / | 0.456 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.456 | |
| 3mg3 | ECH | Orange carotenoid-binding protein | / | 0.456 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.456 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.456 | |
| 4o59 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.456 | |
| 1bv9 | XV6 | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.455 | |
| 2z0y | SAM | Ribosomal RNA small subunit methyltransferase E | / | 0.455 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.455 | |
| 4fg8 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.455 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.455 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.455 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.455 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.455 | |
| 1e8x | ATP | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.454 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.454 | |
| 2w2l | NAD | D-mandelate dehydrogenase | / | 0.454 | |
| 3be9 | P04 | Casein kinase II subunit alpha | 2.7.11.1 | 0.454 | |
| 3flw | FLW | Mitogen-activated protein kinase 14 | / | 0.454 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.454 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.454 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.454 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.454 | |
| 4lva | 20M | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.454 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.453 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.453 | |
| 1i24 | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.453 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.453 | |
| 1qvn | FRI | Interleukin-2 | / | 0.453 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.453 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.453 | |
| 3t8o | ATP | Rhodopsin kinase | / | 0.453 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.453 | |
| 4jaz | STL | Peroxisome proliferator-activated receptor gamma | / | 0.453 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 1fml | RTL | Retinol dehydratase | / | 0.452 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.452 | |
| 2q70 | DC8 | Estrogen receptor | / | 0.452 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.452 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.452 | |
| 3pe6 | ZYH | Monoglyceride lipase | / | 0.452 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.452 | |
| 1gd1 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.451 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.451 | |
| 1lp4 | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.451 | |
| 1z1f | STL | Resveratrol synthase | / | 0.451 | |
| 2pvm | P29 | Casein kinase II subunit alpha | 2.7.11.1 | 0.451 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.451 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.451 | |
| 3t3c | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.450 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.450 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.450 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.450 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.450 | |
| 3vwd | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.450 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.450 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.450 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.449 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 2xs0 | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.449 | |
| 3a7j | ADP | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.449 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.449 | |
| 3hdm | MMG | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.449 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.449 | |
| 3rk5 | 07Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 3vid | 4TT | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.449 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.449 | |
| 3zep | 1NX | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.449 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 4kio | G5K | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.449 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.449 | |
| 1met | DMP | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.448 | |
| 2bd0 | NAP | Sepiapterin reductase | / | 0.448 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.448 | |
| 2xvu | 9DN | Serum albumin | / | 0.448 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.448 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.448 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.448 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.448 | |
| 4fkr | 45K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 4xwt | U5P | Ribonuclease J | / | 0.448 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.448 | |
| 1bdr | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.447 | |
| 1gyp | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.447 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.447 | |
| 1m2p | HNA | Casein kinase II subunit alpha | 2.7.11.1 | 0.447 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.447 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.447 | |
| 2pvn | P63 | Casein kinase II subunit alpha | 2.7.11.1 | 0.447 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.447 | |
| 3fnl | SHA | Lactoperoxidase | / | 0.447 | |
| 3ggp | NAD | Prephenate dehydrogenase | / | 0.447 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.447 | |
| 3p8z | SAH | Genome polyprotein | 2.1.1.56 | 0.447 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
| 4qmz | B49 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.447 | |
| 5cvh | ADP | Casein kinase II subunit alpha | 2.7.11.1 | 0.447 | |
| 1cer | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.446 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.446 | |
| 1pox | FAD | Pyruvate oxidase | 1.2.3.3 | 0.446 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 2v9j | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.446 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.446 | |
| 4e6d | 0NU | Tyrosine-protein kinase JAK2 | / | 0.446 | |
| 4jin | 1L7 | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.446 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.446 | |
| 1q6t | 600 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.445 | |
| 1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.445 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.445 | |
| 2x1n | X1N | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3gu8 | 3GU | Death-associated protein kinase 1 | 2.7.11.1 | 0.445 | |
| 3i4b | Z48 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.445 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.445 | |
| 3r7e | X88 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.445 | |
| 4b5p | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.445 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.445 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 4l7f | 1V5 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.445 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.445 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.445 | |
| 5iqi | GNP | Bifunctional AAC/APH | 2.3.1 | 0.445 | |
| 1h2b | NAJ | NAD-dependent alcohol dehydrogenase | / | 0.444 | |
| 1kh2 | ATP | Argininosuccinate synthase | / | 0.444 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.444 | |
| 1msn | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 1u4o | NDD | L-lactate dehydrogenase | 1.1.1.27 | 0.444 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.444 | |
| 2vn9 | GVD | Calcium/calmodulin-dependent protein kinase type II subunit delta | 2.7.11.17 | 0.444 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.444 | |
| 3q5d | GDP | Atlastin-1 | 3.6.5 | 0.444 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 4dja | FAD | (6-4) photolyase | / | 0.444 | |
| 4mcc | 21X | tRNA (guanine-N(1)-)-methyltransferase | 2.1.1.228 | 0.444 | |
| 4rrr | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.444 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.443 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.443 | |
| 2bxm | IMN | Serum albumin | / | 0.443 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.443 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.443 | |
| 2qhm | 7CS | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3a14 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.443 | |
| 3bw4 | FMN | Putative 2-nitropropane dioxygenase | / | 0.443 | |
| 3cd3 | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.443 | |
| 3hrf | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
| 3qu0 | X40 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.443 | |
| 4d9t | 0JG | Ribosomal protein S6 kinase alpha-3 | 2.7.11.1 | 0.443 | |
| 4m6p | 20R | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.443 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.443 | |
| 4q1y | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.443 | |
| 5hg0 | SAM | Pantothenate synthetase | / | 0.443 | |
| 5kf9 | ACO | Predicted acetyltransferase | / | 0.443 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.442 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.442 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.442 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.442 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2bxo | OPB | Serum albumin | / | 0.442 | |
| 2cch | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2uzv | SS5 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 2w71 | L23 | Biotin carboxylase | 6.3.4.14 | 0.442 | |
| 2y3r | TRK | TamL | / | 0.442 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 3fri | SAH | 16S rRNA methylase | / | 0.442 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.442 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.442 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.442 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.442 | |
| 3w32 | W32 | Epidermal growth factor receptor | 2.7.10.1 | 0.442 | |
| 4b65 | FAD | L-ornithine N(5)-monooxygenase | / | 0.442 | |
| 4cgf | UJ6 | Integrase | / | 0.442 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 5e8y | STU | TGF-beta receptor type-2 | 2.7.11.30 | 0.442 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.442 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.441 | |
| 1h74 | AGS | Homoserine kinase | 2.7.1.39 | 0.441 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.441 | |
| 1rv1 | IMZ | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.441 | |
| 1stc | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.441 | |
| 2uzt | SS3 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 2w0b | CMW | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.441 | |
| 2xnb | Y8L | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3bht | MFR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3d8b | ADP | Fidgetin-like protein 1 | 3.6.4 | 0.441 | |
| 3eks | CY9 | Actin-5C | / | 0.441 | |
| 3eyh | IZA | Tyrosine-protein kinase JAK1 | / | 0.441 | |
| 3kb6 | NAD | D-lactate dehydrogenase | / | 0.441 | |
| 3lvf | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1 | / | 0.441 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.441 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.441 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.441 | |
| 4aot | GW8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.441 | |
| 4b4d | FAD | Ferredoxin-NADP reductase | / | 0.441 | |
| 4fv2 | EK5 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.441 | |
| 4fv5 | EK9 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.441 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.441 | |
| 4hgs | 15G | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.441 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.441 | |
| 4rqk | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.441 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.441 | |
| 1b16 | NAQ | Alcohol dehydrogenase | 1.1.1.1 | 0.440 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1k6v | XN2 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1nqa | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.440 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1u54 | ACP | Activated CDC42 kinase 1 | / | 0.440 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.440 | |
| 1y57 | MPZ | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.440 | |
| 1zp9 | ATP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.440 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.440 | |
| 2c5y | MTW | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.440 | |
| 2ix5 | FAD | Acyl-coenzyme A oxidase 4, peroxisomal | 1.3.3.6 | 0.440 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.440 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.440 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
| 3fx5 | KNI | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.440 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3uxy | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.440 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.440 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.440 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.440 | |
| 4fkw | 62K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 4g6g | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.440 | |
| 4g6n | EK0 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.440 | |
| 4lcf | 1WL | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.440 | |
| 4mwh | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 4o4f | ATP | Kinase | / | 0.440 | |
| 4otp | ADP | Serine/threonine-protein kinase RIO1 | 2.7.11.1 | 0.440 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.440 |