sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3znr | NU9 | Histone deacetylase 7 | 3.5.1.98 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3znr | NU9 | Histone deacetylase 7 | 3.5.1.98 | 1.000 | |
| 3zns | NU7 | Histone deacetylase 7 | 3.5.1.98 | 0.611 | |
| 4cby | KEE | Histone deacetylase 4 | 3.5.1.98 | 0.602 | |
| 3c10 | TSN | Histone deacetylase 7 | 3.5.1.98 | 0.570 | |
| 2vqj | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.556 | |
| 4k9y | K9Y | Focal adhesion kinase 1 | 2.7.10.2 | 0.542 | |
| 3uza | T4G | Adenosine receptor A2a | / | 0.530 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.520 | |
| 3c0z | SHH | Histone deacetylase 7 | 3.5.1.98 | 0.520 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.517 | |
| 1ejb | INJ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.516 | |
| 4qx5 | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.516 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.515 | |
| 3h4v | DVP | Pteridine reductase 1 | 1.5.1.33 | 0.515 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.511 | |
| 3srs | M23 | Dihydrofolate reductase | 1.5.1.3 | 0.510 | |
| 4a4x | JUP | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.510 | |
| 2z7g | EH9 | Adenosine deaminase | 3.5.4.4 | 0.508 | |
| 4dm8 | REA | Retinoic acid receptor beta | / | 0.508 | |
| 3uzc | T4E | Adenosine receptor A2a | / | 0.508 | |
| 1ne4 | RP1 | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.506 | |
| 4imf | SI3 | N-acetylneuraminate lyase | / | 0.505 | |
| 3gie | ACP | Sensor histidine kinase DesK | 2.7.13.3 | 0.504 | |
| 3ele | PLP | Aminotransferase | / | 0.503 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.503 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.500 | |
| 1dr4 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.498 | |
| 2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.498 | |
| 5kf9 | ACO | Predicted acetyltransferase | / | 0.498 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.497 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.497 | |
| 4fev | PP1 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.497 | |
| 2pul | ACP | Methylthioribose kinase | 2.7.1.100 | 0.495 | |
| 3up3 | XCA | aceDAF-12 | / | 0.495 | |
| 2qhx | FE1 | Pteridine reductase 1 | 1.5.1.33 | 0.493 | |
| 3hbf | MYC | Flavonoid 3-O-glucosyltransferase | 2.4.1 | 0.493 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.493 | |
| 3lfz | ADP | Uncharacterized protein MJ1225 | / | 0.491 | |
| 3p9t | TCL | Repressor | / | 0.491 | |
| 3blo | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.490 | |
| 5kf8 | ACO | Predicted acetyltransferase | / | 0.490 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.490 | |
| 1uml | FR4 | Adenosine deaminase | 3.5.4.4 | 0.489 | |
| 3nxr | D2D | Dihydrofolate reductase | 1.5.1.3 | 0.489 | |
| 4aos | NAP | Steroid monooxygenase | / | 0.489 | |
| 2xkf | BX1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.488 | |
| 4qii | 2NE | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.488 | |
| 2pl0 | STI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.486 | |
| 3l3r | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.486 | |
| 4equ | G6I | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.486 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.486 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.486 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.486 | |
| 3arv | SAU | Chitinase A | / | 0.485 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.485 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.485 | |
| 2c94 | TSF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.484 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.484 | |
| 4gkh | 0J9 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.484 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.484 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.483 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.483 | |
| 2io6 | 330 | Wee1-like protein kinase | 2.7.10.2 | 0.483 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.483 | |
| 3nxo | D2B | Dihydrofolate reductase | 1.5.1.3 | 0.483 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.482 | |
| 2w3a | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.482 | |
| 2w6z | L21 | Biotin carboxylase | 6.3.4.14 | 0.482 | |
| 3new | 3NE | Mitogen-activated protein kinase 14 | / | 0.482 | |
| 3x06 | 5GP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.482 | |
| 5bvw | 1N1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.482 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.481 | |
| 3vv8 | B02 | Beta-secretase 1 | 3.4.23.46 | 0.481 | |
| 3zsh | 469 | Mitogen-activated protein kinase 14 | / | 0.481 | |
| 4c6z | TLE | 3-oxoacyl-ACP synthase | / | 0.481 | |
| 1e79 | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.480 | |
| 1e79 | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.480 | |
| 1el4 | CTZ | Obelin | / | 0.480 | |
| 2bfp | H4B | Pteridine reductase 1 | 1.5.1.33 | 0.480 | |
| 3be2 | RAJ | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.480 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.480 | |
| 4a4l | 939 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.480 | |
| 4a4o | 664 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.480 | |
| 4i6f | 1C7 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.480 | |
| 1qv0 | CZH | Obelin | / | 0.479 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.479 | |
| 1uwh | BAX | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.479 | |
| 2bfa | CB3 | Pteridine reductase 1 | 1.5.1.33 | 0.479 | |
| 2wqo | VGK | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.479 | |
| 2xk3 | XK3 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.479 | |
| 2xk7 | 30E | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.479 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 4h1j | 0YH | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.479 | |
| 4j52 | 1J3 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.479 | |
| 1qv1 | CZH | Obelin | / | 0.478 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.478 | |
| 3ikt | NAD | Redox-sensing transcriptional repressor Rex | / | 0.478 | |
| 3nxy | D2H | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.478 | |
| 4feu | 537 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.478 | |
| 5kgh | ACO | Predicted acetyltransferase | / | 0.478 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.478 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.477 | |
| 4gki | 0JN | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.477 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.476 | |
| 1kyy | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.476 | |
| 1syn | F89 | Thymidylate synthase | / | 0.476 | |
| 2pui | ADP | Methylthioribose kinase | 2.7.1.100 | 0.476 | |
| 3nxt | D2E | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.476 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.476 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.476 | |
| 3rey | XAC | Adenosine receptor A2a | / | 0.476 | |
| 1e92 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.475 | |
| 2zb8 | IMN | Prostaglandin reductase 2 | 1.3.1.48 | 0.475 | |
| 3bmq | AX5 | Pteridine reductase | / | 0.475 | |
| 4hsh | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.475 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.475 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.474 | |
| 1s9d | AFB | Cytohesin-2 | / | 0.474 | |
| 1s9d | AFB | ADP-ribosylation factor 1 | / | 0.474 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.474 | |
| 3djf | BC3 | Purine nucleoside phosphorylase | / | 0.474 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.474 | |
| 4da6 | GA2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.474 | |
| 4iah | 1DX | Alr2278 protein | / | 0.474 | |
| 1fw0 | KAI | Glutamate receptor 2 | / | 0.473 | |
| 2ejz | SAH | Diphthine synthase | / | 0.473 | |
| 2rdn | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.473 | |
| 2rjp | 886 | A disintegrin and metalloproteinase with thrombospondin motifs 4 | 3.4.24.82 | 0.473 | |
| 2xkd | T3M | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.473 | |
| 2xnp | WCX | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.473 | |
| 3fvq | ATP | Fe(3+) ions import ATP-binding protein FbpC | / | 0.473 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.473 | |
| 3nh8 | DC2 | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) | 3.5.1.114 | 0.473 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.473 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 4agw | NG7 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.473 | |
| 4da7 | AC2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.473 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.473 | |
| 4iae | 1DX | Alr2278 protein | / | 0.473 | |
| 5bn3 | ADP | V-type ATP synthase alpha chain | / | 0.473 | |
| 5bn3 | ADP | NEQ263 | / | 0.473 | |
| 3rfm | CFF | Adenosine receptor A2a | / | 0.473 | |
| 1k4g | AIQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.472 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.472 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.472 | |
| 4f31 | KAI | Glutamate receptor 3 | / | 0.472 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.472 | |
| 3pwh | ZMA | Adenosine receptor A2a | / | 0.472 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.472 | |
| 1jf2 | CZH | Obelin | / | 0.471 | |
| 1lhw | ESM | Sex hormone-binding globulin | / | 0.471 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.471 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.471 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 2w6m | OA1 | Biotin carboxylase | 6.3.4.14 | 0.471 | |
| 2xtb | KRM | Adenosine kinase, putative | / | 0.471 | |
| 2yac | 937 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.471 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.471 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.471 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.471 | |
| 5doz | NDP | JamJ | / | 0.471 | |
| 5kgj | ACO | Predicted acetyltransferase | / | 0.471 | |
| 1hk4 | T44 | Serum albumin | / | 0.470 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.470 | |
| 1r8q | AFB | Cytohesin-2 | / | 0.470 | |
| 1r8q | AFB | ADP-ribosylation factor 1 | / | 0.470 | |
| 1s2c | FLF | Aldo-keto reductase family 1 member C3 | / | 0.470 | |
| 1yqs | BSA | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.470 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.470 | |
| 2vte | IK4 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.470 | |
| 3d4b | DZD | NAD-dependent protein deacetylase | / | 0.470 | |
| 3nxv | D2F | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 3r7m | SUZ | Aldo-keto reductase family 1 member C3 | / | 0.470 | |
| 4jqa | ID8 | Aldo-keto reductase family 1 member C2 | / | 0.470 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.469 | |
| 1yc2 | NAD | NAD-dependent protein deacylase 2 | / | 0.469 | |
| 2jh0 | 701 | Prothrombin | 3.4.21.5 | 0.469 | |
| 2oiq | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.469 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.469 | |
| 2z2w | 770 | Wee1-like protein kinase | 2.7.10.2 | 0.469 | |
| 3c34 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.469 | |
| 3cth | 319 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.469 | |
| 3frf | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 3gcq | 1BU | Mitogen-activated protein kinase 14 | / | 0.469 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.469 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.469 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.469 | |
| 4mrx | CZH | Obelin | / | 0.469 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.469 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.468 | |
| 1swt | BTN | Streptavidin | / | 0.468 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.468 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.468 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.468 | |
| 3jwt | JI5 | Nitric oxide synthase, brain | 1.14.13.39 | 0.468 | |
| 4at4 | T6E | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.468 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.468 | |
| 4h3g | 10Q | Beta-secretase 1 | 3.4.23.46 | 0.468 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.467 | |
| 1vhn | FMN | tRNA-dihydrouridine synthase | / | 0.467 | |
| 2b35 | TCL | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.467 | |
| 2gou | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.467 | |
| 2obx | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | 2.5.1.78 | 0.467 | |
| 2olc | ADP | Methylthioribose kinase | 2.7.1.100 | 0.467 | |
| 2xke | WI2 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.467 | |
| 2yat | EEU | Estrogen receptor | / | 0.467 | |
| 3ba6 | AN2 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.467 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.467 | |
| 3oji | PYV | Abscisic acid receptor PYL3 | / | 0.467 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.467 | |
| 4djw | 0KP | Beta-secretase 1 | 3.4.23.46 | 0.467 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.467 | |
| 4hqv | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.467 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.467 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.467 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.467 | |
| 1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.466 | |
| 1lbb | KAI | Glutamate receptor 2 | / | 0.466 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.466 | |
| 1t13 | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | / | 0.466 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.466 | |
| 2reh | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.466 | |
| 2xkc | 4VQ | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.466 | |
| 2zrz | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.466 | |
| 2zs9 | ADP | Pantothenate kinase | 2.7.1.33 | 0.466 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.466 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.466 | |
| 4olf | HFG | Proline--tRNA ligase | 6.1.1.15 | 0.466 | |
| 5agy | GTB | Tau class glutathione S-transferase | / | 0.466 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.466 | |
| 1c7o | PPG | Hemolysin | / | 0.465 | |
| 1ihi | IU5 | Aldo-keto reductase family 1 member C2 | / | 0.465 | |
| 1x8b | 824 | Wee1-like protein kinase | 2.7.10.2 | 0.465 | |
| 2qqf | A1R | NAD-dependent protein deacetylase HST2 | 3.5.1 | 0.465 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.465 | |
| 3lv1 | NAP | NAD(P)-dependent benzaldehyde dehydrogenase | 1.2.1.28 | 0.465 | |
| 3q2j | CKI | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.465 | |
| 3qpg | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.465 | |
| 3zks | WZV | Beta-secretase 2 | 3.4.23.45 | 0.465 | |
| 3zs5 | SB2 | Mitogen-activated protein kinase 14 | / | 0.465 | |
| 4h6z | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.465 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.465 | |
| 1hfr | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.464 | |
| 1yqj | 6NP | Mitogen-activated protein kinase 14 | / | 0.464 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.464 | |
| 2x9v | TMQ | Pteridine reductase | / | 0.464 | |
| 2zru | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.464 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.464 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.464 | |
| 3vil | SA0 | Beta-glucosidase | / | 0.464 | |
| 3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.464 | |
| 4ax8 | SAM | O-antigen chain terminator bifunctional methyltransferase/kinase WbdD | / | 0.464 | |
| 4da8 | BG2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.464 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.464 | |
| 4l1x | STR | Aldo-keto reductase family 1 member C2 | / | 0.464 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.464 | |
| 5d1b | TSN | Histone deacetylase 8 | 3.5.1.98 | 0.464 | |
| 5kf2 | ACO | Predicted acetyltransferase | / | 0.464 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.463 | |
| 1rgs | CMP | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.463 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.463 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.463 | |
| 2bfm | TOP | Pteridine reductase 1 | 1.5.1.33 | 0.463 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.463 | |
| 2in6 | 839 | Wee1-like protein kinase | 2.7.10.2 | 0.463 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.463 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.463 | |
| 2pup | ADP | Methylthioribose kinase | 2.7.1.100 | 0.463 | |
| 2xk6 | EQH | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.463 | |
| 2y0d | UGA | UDP-glucose dehydrogenase | / | 0.463 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.463 | |
| 3oez | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.463 | |
| 3uwe | VJJ | Aldo-keto reductase family 1 member C3 | / | 0.463 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.463 | |
| 4b05 | 32D | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 4b78 | KGG | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 4du6 | GTP | GTP cyclohydrolase 1 | / | 0.463 | |
| 4fri | DWA | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.463 | |
| 4rra | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.463 | |
| 4s1i | PLP | Pyridoxal kinase, putative | / | 0.463 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.463 | |
| 1g7v | PAI | 2-dehydro-3-deoxyphosphooctonate aldolase | 2.5.1.55 | 0.462 | |
| 1icq | OPD | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.462 | |
| 1jdz | FMB | Purine nucleoside phosphorylase | / | 0.462 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.462 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.462 | |
| 2ojg | 19A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.462 | |
| 3cas | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.462 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.462 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.462 | |
| 4azy | 7F3 | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 4bwa | N0B | Pyrrolysine--tRNA ligase | / | 0.462 | |
| 4kln | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.462 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.462 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.462 | |
| 5epv | ACP | Blue-light-activated histidine kinase | 2.7.13.3 | 0.462 | |
| 1dls | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 2w3m | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.461 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.461 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.461 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.461 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.461 | |
| 4g34 | 924 | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.461 | |
| 4h1e | 10J | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 4m48 | 21B | Sodium-dependent dopamine transporter | / | 0.461 | |
| 4oe4 | NAD | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | 1.2.1.88 | 0.461 | |
| 1dgb | NDP | Catalase | 1.11.1.6 | 0.460 | |
| 1n5v | NOM | ActVA 6 protein | / | 0.460 | |
| 1qs2 | NAD | Vip2Ac | / | 0.460 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.460 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.460 | |
| 1vkg | CRI | Histone deacetylase 8 | 3.5.1.98 | 0.460 | |
| 2a4x | BLM | Mitomycin-binding protein | / | 0.460 | |
| 2o65 | MYF | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.460 | |
| 2w0h | NDP | Trypanothione reductase | / | 0.460 | |
| 2xk4 | OL2 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.460 | |
| 3bld | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.460 | |
| 3co9 | 3MS | Genome polyprotein | 2.7.7.48 | 0.460 | |
| 3ctj | 320 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.460 | |
| 3djl | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.460 | |
| 3huc | G97 | Mitogen-activated protein kinase 14 | / | 0.460 | |
| 3q2m | CKI | Spectinomycin phosphotransferase | / | 0.460 | |
| 3rql | X2D | Nitric oxide synthase, brain | 1.14.13.39 | 0.460 | |
| 3sru | Q26 | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.460 | |
| 4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 4i6h | 1C8 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.460 | |
| 4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.460 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.460 | |
| 1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.459 | |
| 1p33 | MTX | Pteridine reductase 1 | 1.5.1.33 | 0.459 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.459 | |
| 2c9d | PHR | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.459 | |
| 2rab | NAD | Glutathione amide reductase | / | 0.459 | |
| 3aw9 | GDU | NAD-dependent epimerase/dehydratase | / | 0.459 | |
| 3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.459 | |
| 3k47 | D09 | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 3ugr | IMN | Aldo-keto reductase family 1 member C3 | / | 0.459 | |
| 3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.459 | |
| 4azw | SAM | O-antigen chain terminator bifunctional methyltransferase/kinase WbdD | / | 0.459 | |
| 4ybn | FAD | Flavin-nucleotide-binding protein | / | 0.459 | |
| 1afs | TES | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.458 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 1g3m | PCQ | Estrogen sulfotransferase | 2.8.2.4 | 0.458 | |
| 1gt5 | BZQ | Odorant-binding protein | / | 0.458 | |
| 1q63 | AIQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.458 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.458 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.458 | |
| 1ych | FMN | Nitric oxide reductase | 1 | 0.458 | |
| 2fjm | 073 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.458 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.458 | |
| 2poq | ISD | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase | 1.3.1.20 | 0.458 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.458 | |
| 3gb4 | D3M | DdmC | / | 0.458 | |
| 3hv3 | R49 | Mitogen-activated protein kinase 14 | / | 0.458 | |
| 3lql | LDT | Aldose reductase | 1.1.1.21 | 0.458 | |
| 3rgz | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.458 | |
| 3rm8 | RM8 | Acidic mammalian chitinase | 3.2.1.14 | 0.458 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.458 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.458 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.458 | |
| 4cav | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.458 | |
| 4ixd | 1HV | Integrin alpha-L | / | 0.458 | |
| 4jey | PLP | Acetylornithine/succinyldiaminopimelate aminotransferase | 2.6.1.11 | 0.458 | |
| 4qtu | SAM | 18S rRNA (guanine(1575)-N(7))-methyltransferase | / | 0.458 | |
| 5c1g | GDU | Histo-blood group ABO system transferase | / | 0.458 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.457 | |
| 1y6o | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.457 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.457 | |
| 2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.457 | |
| 2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.457 | |
| 2i0z | FAD | NAD(FAD)-utilizing dehydrogenases | / | 0.457 | |
| 2jav | 5Z5 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.457 | |
| 2ovy | PFJ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.457 | |
| 3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.457 | |
| 3n5w | XFJ | Nitric oxide synthase, brain | 1.14.13.39 | 0.457 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 4ckr | DI1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.457 | |
| 4djx | 0KQ | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 4gi2 | NAP | Crotonyl-CoA carboxylase/reductase | / | 0.457 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.457 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.457 | |
| 1iah | ADP | Transient receptor potential cation channel subfamily M member 7 | 2.7.11.1 | 0.456 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.456 | |
| 1xzq | FON | tRNA modification GTPase MnmE | 3.6.5 | 0.456 | |
| 2am2 | 2LG | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.456 | |
| 2e99 | B08 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.456 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.456 | |
| 2oli | IOP | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.456 | |
| 2p15 | EZT | Estrogen receptor | / | 0.456 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.456 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.456 | |
| 3nmv | PYV | Abscisic acid receptor PYL2 | / | 0.456 | |
| 3p0e | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.456 | |
| 3prf | FP3 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.456 | |
| 3s41 | S41 | Glucokinase | 2.7.1.2 | 0.456 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.456 | |
| 4b5n | FMN | NAD(P)H:flavin oxidoreductase Sye4 | / | 0.456 | |
| 4ixf | IXF | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 4nqg | CZH | Mitrocomin | / | 0.456 | |
| 4std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.456 | |
| 4tqq | UQ1 | Reaction center protein L chain | / | 0.456 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.456 | |
| 5dn1 | AMZ | Phosphoribosyl isomerase A | 5.3.1.16 | 0.456 | |
| 1a4i | NDP | C-1-tetrahydrofolate synthase, cytoplasmic | 1.5.1.5 | 0.455 | |
| 1al7 | HST | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.455 | |
| 1jra | FAD | FAD-linked sulfhydryl oxidase ERV2 | 1.8.3.2 | 0.455 | |
| 1kms | LIH | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1kmv | LII | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.455 | |
| 2b36 | 5PP | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 2ewa | SB2 | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 2ipj | FFA | Aldo-keto reductase family 1 member C2 | / | 0.455 | |
| 2jbl | SMA | Reaction center protein L chain | / | 0.455 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.455 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.455 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.455 | |
| 3hu2 | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.455 | |
| 3k45 | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 3n5x | XFK | Nitric oxide synthase, brain | 1.14.13.39 | 0.455 | |
| 3oq1 | 3OQ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.455 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.455 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.455 | |
| 4dju | 0KK | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.455 | |
| 4qij | 1HA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.455 | |
| 4wx2 | F6F | Tryptophan synthase alpha chain | / | 0.455 | |
| 4wx2 | F6F | Tryptophan synthase beta chain | 4.2.1.20 | 0.455 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.455 | |
| 1dgf | NDP | Catalase | 1.11.1.6 | 0.454 | |
| 1ppj | ANY | Cytochrome b | / | 0.454 | |
| 1ve3 | SAM | Uncharacterized protein | / | 0.454 | |
| 2cle | F6F | Tryptophan synthase alpha chain | / | 0.454 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.454 | |
| 2rku | R78 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.454 | |
| 3c36 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.454 | |
| 3c3e | FO1 | 2-phospho-L-lactate transferase | / | 0.454 | |
| 3cr7 | PPS | Adenylyl-sulfate kinase | 2.7.1.25 | 0.454 | |
| 3f82 | 353 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.454 | |
| 3gts | D3M | DdmC | / | 0.454 | |
| 3lzz | GDP | Uncharacterized protein | / | 0.454 | |
| 3t5i | SER_SER_CMT_FAR | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.454 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.454 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.454 | |
| 4ej1 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.454 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.454 | |
| 4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.454 | |
| 4zzj | CNA | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.454 | |
| 5ckw | ANP | Uncharacterized protein | / | 0.454 | |
| 5d7q | 4I5 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.454 | |
| 1aoe | GW3 | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1dig | L37 | C-1-tetrahydrofolate synthase, cytoplasmic | 1.5.1.5 | 0.453 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1g7u | PEP | 2-dehydro-3-deoxyphosphooctonate aldolase | 2.5.1.55 | 0.453 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.453 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.453 | |
| 1u1d | 181 | Uridine phosphorylase | 2.4.2.3 | 0.453 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 2b0q | ADP | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.453 | |
| 2eix | FAD | NADH-cytochrome b5 reductase | / | 0.453 | |
| 2lbd | REA | Retinoic acid receptor gamma | / | 0.453 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.453 | |
| 3cr0 | 809 | Wee1-like protein kinase | 2.7.10.2 | 0.453 | |
| 3eah | 327 | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.453 | |
| 3fnf | JPM | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 3ft8 | MOJ | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3nwl | NDP | Catalase | 1.11.1.6 | 0.453 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.453 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase alpha chain | 1.13.11.3 | 0.453 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.453 | |
| 3sh2 | 5DR | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.453 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.453 | |
| 3zsg | T75 | Mitogen-activated protein kinase 14 | / | 0.453 | |
| 4dk7 | 0KS | Oxysterols receptor LXR-beta | / | 0.453 | |
| 4dm6 | TTB | Retinoic acid receptor beta | / | 0.453 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4jq3 | ZOM | Aldo-keto reductase family 1 member C2 | / | 0.453 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.453 | |
| 4pkw | GM6 | Lethal factor | 3.4.24.83 | 0.453 | |
| 4uth | FMN | Xenobiotic reductase | / | 0.453 | |
| 5jr3 | 4MU | Carminomycin 4-O-methyltransferase DnrK | 2.1.1.292 | 0.453 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.452 | |
| 1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.452 | |
| 1pr0 | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.452 | |
| 1uym | PU3 | Heat shock protein HSP 90-beta | / | 0.452 | |
| 1vrq | FON | Subunit alpha of sarocosine oxidase | / | 0.452 | |
| 2b1z | 17M | Estrogen receptor | / | 0.452 | |
| 2f98 | NGV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.452 | |
| 2fai | 459 | Estrogen receptor | / | 0.452 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.452 | |
| 3dko | IHZ | Ephrin type-A receptor 7 | 2.7.10.1 | 0.452 | |
| 3htj | ET | EbrA repressor | / | 0.452 | |
| 3o4r | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.452 | |
| 3sl2 | ATP | Sensor histidine kinase WalK | / | 0.452 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 4ezl | 0SE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 4gh3 | 0EV | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.452 | |
| 4iil | RBF | Membrane lipoprotein TpN38(b) | / | 0.452 | |
| 4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 4qjc | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 4rri | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.452 | |
| 4ttj | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.452 | |
| 5dp2 | NAP | CurF | / | 0.452 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.452 | |
| 1fcy | 564 | Retinoic acid receptor gamma | / | 0.451 | |
| 1hk5 | T44 | Serum albumin | / | 0.451 | |
| 1mc1 | PCX | Carboxyethyl-arginine beta-lactam-synthase | 6.3.3.4 | 0.451 | |
| 1qiw | DPD | Calmodulin | / | 0.451 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 1u1c | BAU | Uridine phosphorylase | 2.4.2.3 | 0.451 | |
| 1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.451 | |
| 1zdw | FLV | Prenyltransferase | / | 0.451 | |
| 2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.451 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 2pau | D5M | 5'-deoxynucleotidase YfbR | / | 0.451 | |
| 2w5b | AGS | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.451 | |
| 2w6q | OA5 | Biotin carboxylase | 6.3.4.14 | 0.451 | |
| 3c1x | CKK | Hepatocyte growth factor receptor | 2.7.10.1 | 0.451 | |
| 3dl9 | V2H | Vitamin D 25-hydroxylase | / | 0.451 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.451 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.451 | |
| 3o0i | P54 | Heat shock protein HSP 90-alpha | / | 0.451 | |
| 3zhv | TDW | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.451 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.451 | |
| 4b6l | 9ZP | Serine/threonine-protein kinase PLK3 | 2.7.11.21 | 0.451 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.451 | |
| 4fgc | PQ0 | NADPH-dependent 7-cyano-7-deazaguanine reductase | 1.7.1.13 | 0.451 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 4i42 | 1HA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.451 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.451 | |
| 4ocv | ANP | Aminoglycoside phosphotransferase | / | 0.451 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.451 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.451 | |
| 4rxp | DTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.451 | |
| 4trj | 665 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.451 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.451 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.451 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.450 | |
| 1ej3 | CZH | Aequorin-2 | / | 0.450 | |
| 1f5f | DHT | Sex hormone-binding globulin | / | 0.450 | |
| 1fd0 | 254 | Retinoic acid receptor gamma | / | 0.450 | |
| 1nce | CB3 | Thymidylate synthase | / | 0.450 | |
| 1nqv | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.450 | |
| 1rxj | BNI | Streptavidin | / | 0.450 | |
| 1t4c | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.450 | |
| 1v79 | FR7 | Adenosine deaminase | 3.5.4.4 | 0.450 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.450 | |
| 2qg2 | A91 | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 2qjp | ANJ | Cytochrome b | / | 0.450 | |
| 2y0j | AXC | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.450 | |
| 3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.450 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.450 | |
| 3cgy | RDC | Virulence sensor histidine kinase PhoQ | 2.7.13.3 | 0.450 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3g5m | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.450 | |
| 3gkj | HC3 | Niemann-Pick C1 protein | / | 0.450 | |
| 3gue | UPG | UTP-glucose-1-phosphate uridylyltransferase 2, putative | / | 0.450 | |
| 3h1v | TK1 | Glucokinase | 2.7.1.2 | 0.450 | |
| 3imx | B84 | Glucokinase | 2.7.1.2 | 0.450 | |
| 3ix4 | TX1 | Transcriptional activator protein LasR | / | 0.450 | |
| 3qv1 | NAD | Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic | 1.2.1.13 | 0.450 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.450 | |
| 3zc3 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.450 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.450 | |
| 4bew | ACP | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.450 | |
| 4dhy | S41 | Glucokinase | 2.7.1.2 | 0.450 | |
| 4gus | FAD | Lysine-specific histone demethylase 1B | 1 | 0.450 | |
| 4hni | 16W | Casein kinase I isoform epsilon | 2.7.11.1 | 0.450 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.450 | |
| 4rh1 | 0TT | Spore photoproduct lyase | / | 0.450 | |
| 1mcz | RMN | Benzoylformate decarboxylase | 4.1.1.7 | 0.449 | |
| 1toj | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.449 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2b8j | ADN | Class B acid phosphatase | 3.1.3.2 | 0.449 | |
| 2c4c | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.449 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.449 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.449 | |
| 2xje | U5P | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.449 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.449 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.449 | |
| 3hu1 | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.449 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 3pne | 8AX | Nitric oxide synthase, brain | 1.14.13.39 | 0.449 | |
| 3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.449 | |
| 3vgn | FNN | Steroid Delta-isomerase | 5.3.3.1 | 0.449 | |
| 4b00 | I6X | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4ea2 | RWZ | Dehydrosqualene synthase | / | 0.449 | |
| 4fc0 | 0T2 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.449 | |
| 4fk3 | 325 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.449 | |
| 4gvs | F4M | Methenyltetrahydromethanopterin cyclohydrolase | 3.5.4.27 | 0.449 | |
| 4h3i | 10V | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.449 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.449 | |
| 4kc2 | WS2 | Histo-blood group ABO system transferase | / | 0.449 | |
| 4kfj | 1R0 | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 4uof | DAT | Nucleoside diphosphate kinase | / | 0.449 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.449 | |
| 4uhr | NGI | Adenosine receptor A2a | / | 0.449 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.448 | |
| 1db4 | 8IN | Phospholipase A2, membrane associated | / | 0.448 | |
| 1jcq | 739 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.448 | |
| 1jf0 | CZH | Obelin | / | 0.448 | |
| 1odj | GMP | Purine nucleoside phosphorylase | / | 0.448 | |
| 1oe0 | TTP | Deoxynucleoside kinase | / | 0.448 | |
| 1u0w | STL | Chalcone synthase 2 | 2.3.1.74 | 0.448 | |
| 1w19 | T4P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.448 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2d06 | EST | Sulfotransferase 1A1 | 2.8.2.1 | 0.448 | |
| 2fs4 | PZ1 | Renin | 3.4.23.15 | 0.448 | |
| 2j0v | GDP | Rac-like GTP-binding protein ARAC7 | / | 0.448 | |
| 2k1q | GLU_LEU_IBU_OBF_FE3 | Polyprotein | / | 0.448 | |
| 2mjp | ANP | dITP/XTP pyrophosphatase | 3.6.1.19 | 0.448 | |
| 2o8h | 227 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 2od7 | A1R | NAD-dependent protein deacetylase HST2 | 3.5.1 | 0.448 | |
| 2vd0 | D27 | Hematopoietic prostaglandin D synthase | / | 0.448 | |
| 2ykv | IK2 | Beta-transaminase | / | 0.448 | |
| 3aiq | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic | 3.2.1.182 | 0.448 | |
| 3eon | 341 | Glutaryl-CoA dehydrogenase | / | 0.448 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.448 | |
| 3l5l | FMN | Xenobiotic reductase | / | 0.448 | |
| 3l67 | FMN | Xenobiotic reductase | / | 0.448 | |
| 3lfe | Z84 | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 3oom | 507 | Activin receptor type-1 | 2.7.11.30 | 0.448 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 3u4o | 08E | Genome polyprotein | 2.7.7.48 | 0.448 | |
| 4b6u | M7G | Eukaryotic translation initiation factor 4E type 3 | / | 0.448 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.448 | |
| 4cx5 | HW8 | Nitric oxide synthase, brain | 1.14.13.39 | 0.448 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.448 | |
| 4gmg | NAP | Yersiniabactin biosynthetic protein YbtU | / | 0.448 | |
| 4gt8 | ADP | Sensor protein VraS | 2.7.13.3 | 0.448 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 4hmn | 16J | Aldo-keto reductase family 1 member C3 | / | 0.448 | |
| 4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4daj | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.448 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.447 | |
| 1ivr | CBA | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.447 | |
| 1jcm | 137 | Tryptophan biosynthesis protein TrpCF | 4.1.1.48 | 0.447 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 1mlz | PLP | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.447 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 1rpw | DID | HTH-type transcriptional regulator QacR | / | 0.447 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 1zyd | ATP | eIF-2-alpha kinase GCN2 | / | 0.447 | |
| 2gqg | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.447 | |
| 2owb | 626 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.447 | |
| 2pun | ACP | Methylthioribose kinase | 2.7.1.100 | 0.447 | |
| 2qk8 | MTX | Dihydrofolate reductase | / | 0.447 | |
| 3fyw | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3ge7 | AFQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.447 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.447 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.447 | |
| 3rbq | GLY_ALA_GLY_ALA_DAO | Protein unc-119 homolog A | / | 0.447 | |
| 3tyd | XHP | Dihydropteroate synthase | / | 0.447 | |
| 3vkj | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.447 | |
| 4ajg | F07 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.447 | |
| 4eer | FMN | Phototropin-2 | 2.7.11.1 | 0.447 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.447 | |
| 4fex | 0TO | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.447 | |
| 4fwj | FAD | Lysine-specific histone demethylase 1B | 1 | 0.447 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.447 | |
| 4jva | 1OR | cAMP-dependent protein kinase type II-beta regulatory subunit | / | 0.447 | |
| 4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 4oma | LCS | Methionine gamma-lyase | / | 0.447 | |
| 4tzt | 468 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 4v12 | POG | MaoC like domain protein | / | 0.447 | |
| 4wcx | SAM | Biotin and thiamin synthesis associated | / | 0.447 | |
| 4y1b | NAP | AntE | / | 0.447 | |
| 1ek2 | CDU | Bifunctional epoxide hydrolase 2 | / | 0.446 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.446 | |
| 1h35 | R01 | Squalene--hopene cyclase | 4.2.1.129 | 0.446 | |
| 1s3w | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1wsv | THH | Aminomethyltransferase, mitochondrial | / | 0.446 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.446 | |
| 2i1m | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.446 | |
| 2o6h | INI | 6,7-dimethyl-8-ribityllumazine synthase 1 | 2.5.1.78 | 0.446 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.446 | |
| 3fzt | 4JZ | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.446 | |
| 3jwc | EKB | Dihydrofolate reductase | / | 0.446 | |
| 3l2k | PXC | EhpF | / | 0.446 | |
| 3l3l | L3L | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.446 | |
| 3nlz | 3XD | Nitric oxide synthase, brain | 1.14.13.39 | 0.446 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.446 | |
| 3r6i | JMS | Aldo-keto reductase family 1 member C3 | / | 0.446 | |
| 3u8d | U8D | Phospholipase A2, membrane associated | / | 0.446 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.446 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 4g09 | 0VD | Histidinol dehydrogenase | / | 0.446 | |
| 4ku7 | PCG | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.446 | |
| 4n1f | CZH | Obelin | / | 0.446 | |
| 4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.446 | |
| 4rrl | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.446 | |
| 5je2 | SAH | Methyl transferase | / | 0.446 | |
| 5kf1 | ACO | Predicted acetyltransferase | / | 0.446 | |
| 5jqh | CAU | Beta-2 adrenergic receptor | / | 0.446 | |
| 1b9i | PXG | 3-amino-5-hydroxybenzoate synthase | 4.2.1.144 | 0.445 | |
| 1h9z | RWF | Serum albumin | / | 0.445 | |
| 1kij | NOV | DNA gyrase subunit B | / | 0.445 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1ne6 | SP1 | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.445 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.445 | |
| 1sjw | NGV | Nogalonic acid methyl ester cyclase | / | 0.445 | |
| 1swg | BTN | Streptavidin | / | 0.445 | |
| 1tsd | F89 | Thymidylate synthase | / | 0.445 | |
| 1xuo | LA1 | Integrin alpha-L | / | 0.445 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.445 | |
| 2cje | DUN | DUTPase | / | 0.445 | |
| 2gpj | FAD | Siderophore-interacting protein | / | 0.445 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3cqe | P91 | Wee1-like protein kinase | 2.7.10.2 | 0.445 | |
| 3iw8 | HIZ | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 3lbo | LDT | Aldose reductase | 1.1.1.21 | 0.445 | |
| 3nga | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.445 | |
| 3rj0 | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.445 | |
| 3uax | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.445 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.445 | |
| 4af3 | VX6 | Aurora kinase B | 2.7.11.1 | 0.445 | |
| 4b2g | V1N | Uncharacterized protein | / | 0.445 | |
| 4f1m | ACP | Probable serine/threonine-protein kinase roco4 | 2.7.11.1 | 0.445 | |
| 4h0y | NAD | Iota toxin component Ia | / | 0.445 | |
| 4lrr | CF9 | Thymidylate synthase | / | 0.445 | |
| 4rrh | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.445 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.445 | |
| 4zhi | ADP | Kinesin-like protein KIF11 | / | 0.445 | |
| 5j60 | FAD | Thioredoxin reductase | / | 0.445 | |
| 5dsg | 0HK | Muscarinic acetylcholine receptor M4 | / | 0.445 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.444 | |
| 1mq0 | BRD | Cytidine deaminase | 3.5.4.5 | 0.444 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.444 | |
| 2bd0 | BIO | Sepiapterin reductase | / | 0.444 | |
| 2h44 | 7CA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.444 | |
| 2jg7 | NAD | Antiquitin | / | 0.444 | |
| 2pbw | DOQ | Glutamate receptor ionotropic, kainate 1 | / | 0.444 | |
| 2vz0 | D64 | Pteridine reductase | / | 0.444 | |
| 2w5a | ADP | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.444 | |
| 2zrv | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.444 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.444 | |
| 3bi5 | FAD | Polyamine oxidase FMS1 | / | 0.444 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.444 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.444 | |
| 3d5w | ADP | Serine/threonine-protein kinase PLK | / | 0.444 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.444 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.444 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 3srr | Q20 | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3upr | 1KX | HLA class I histocompatibility antigen, B-57 alpha chain | / | 0.444 | |
| 4b5o | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.444 | |
| 4bur | NAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.444 | |
| 4elf | 35I | Dihydrofolate reductase | / | 0.444 | |
| 4h38 | 0YX | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.444 | |
| 4h3f | 10O | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.444 | |
| 4kf1 | HT5 | Aryldialkylphosphatase | 3.1.8.1 | 0.444 | |
| 4p9c | DCM | Deoxycytidylate deaminase | / | 0.444 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.444 | |
| 4xe6 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4y6g | F6F | Tryptophan synthase alpha chain | / | 0.444 | |
| 4yp0 | 5IQ | Histidyl-tRNA synthetase, putative | / | 0.444 | |
| 4zs4 | ATP | Myosin heavy chain kinase A | 2.7.11.7 | 0.444 | |
| 1eno | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.443 | |
| 1exa | 394 | Retinoic acid receptor gamma | / | 0.443 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.443 | |
| 1ikg | REX | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.443 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.443 | |
| 1jxz | BCA | 4-chlorobenzoyl coenzyme A dehalogenase | 3.8.1.7 | 0.443 | |
| 1m8j | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.443 | |
| 1tez | HDF | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.443 | |
| 1v08 | NTZ | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.443 | |
| 2b82 | ADN | Class B acid phosphatase | 3.1.3.2 | 0.443 | |
| 2bxq | IMN | Serum albumin | / | 0.443 | |
| 2c42 | TPP | Pyruvate synthase | / | 0.443 | |
| 2clf | F6F | Tryptophan synthase alpha chain | / | 0.443 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.443 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.443 | |
| 2y03 | 5FW | Beta-1 adrenergic receptor | / | 0.443 | |
| 3b7d | CNI | Glutamate receptor 2 | / | 0.443 | |
| 3bbf | GDP | Nucleoside diphosphate kinase B | 2.7.4.6 | 0.443 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3kro | IPE | Geranyl diphosphate synthase large subunit | / | 0.443 | |
| 3qlx | QLR | Uncharacterized protein | / | 0.443 | |
| 3wi2 | P98 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 3wqu | ATP | Cell division protein FtsA | / | 0.443 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.443 | |
| 3x03 | ANP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.443 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 4do3 | 0LA | Fatty-acid amide hydrolase 1 | 3.5.1.99 | 0.443 | |
| 4eix | NIM | Phospholipase A2 VRV-PL-VIIIa | / | 0.443 | |
| 4fkx | CDP | Nucleoside diphosphate kinase | / | 0.443 | |
| 4gqk | ADP | Actin cross-linking toxin VgrG1 | / | 0.443 | |
| 4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4lv8 | ADP | Rhoptry protein 5 C | / | 0.443 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.443 | |
| 1jqd | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.442 | |
| 1jtq | LY3 | Thymidylate synthase | / | 0.442 | |
| 1p44 | GEQ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 1ra2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1uae | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.442 | |
| 1w2c | ANP | Inositol-trisphosphate 3-kinase A | 2.7.1.127 | 0.442 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.442 | |
| 1xmm | M7G | m7GpppX diphosphatase | 3.6.1.59 | 0.442 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 1z4i | UMP | 5'(3')-deoxyribonucleotidase, mitochondrial | 3.1.3 | 0.442 | |
| 2bak | AQZ | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 2fzb | TOL | Aldose reductase | 1.1.1.21 | 0.442 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.442 | |
| 2oeg | UPG | UDP-glucose pyrophosphorylase | / | 0.442 | |
| 2oz5 | 7XY | Uncharacterized protein | / | 0.442 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2ydv | NEC | Adenosine receptor A2a | / | 0.442 | |
| 2yoj | 8Y6 | Genome polyprotein | 2.7.7.48 | 0.442 | |
| 3mb6 | 01I | Casein kinase II subunit alpha | 2.7.11.1 | 0.442 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.442 | |
| 3o76 | GTB | Glutathione S-transferase P 1 | 2.5.1.18 | 0.442 | |
| 3p2o | NAD | Bifunctional protein FolD | / | 0.442 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3ug8 | IMN | Aldo-keto reductase family 1 member C3 | / | 0.442 | |
| 4a9y | AQZ | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 4fny | I3K | ALK tyrosine kinase receptor | 2.7.10.1 | 0.442 | |
| 4jvl | EST | Estrogen sulfotransferase | 2.8.2.4 | 0.442 | |
| 4plp | NAD | Homospermidine synthase | 2.5.1.44 | 0.442 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.442 | |
| 1efy | BZC | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.441 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 1mra | APG | Mandelate racemase | / | 0.441 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.441 | |
| 1tou | B1V | Fatty acid-binding protein, adipocyte | / | 0.441 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.441 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.441 | |
| 2a19 | ANP | Interferon-induced, double-stranded RNA-activated protein kinase | 2.7.11.1 | 0.441 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.441 | |
| 2f6r | ACO | Bifunctional coenzyme A synthase | / | 0.441 | |
| 2jdd | ACO | Probable acetyltransferase | / | 0.441 | |
| 2nv7 | 555 | Estrogen receptor beta | / | 0.441 | |
| 3akl | ADP | Serine/threonine-protein kinase CtkA | 2.7.11.1 | 0.441 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.441 | |
| 3ewk | FAD | Sensory box histidine kinase/response regulator | / | 0.441 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 3g6z | A7T | Renin | 3.4.23.15 | 0.441 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.441 | |
| 3jq8 | DX3 | Pteridine reductase, putative | / | 0.441 | |
| 3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.441 | |
| 3uyk | 0CX | Probable NDP-rhamnosyltransferase | / | 0.441 | |
| 3v0m | 5GW | Histo-blood group ABO system transferase | / | 0.441 | |
| 4gi4 | 0EX | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.441 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4k36 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.441 | |
| 4kd7 | 9DR | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4l2y | XXK | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | / | 0.441 | |
| 4pkl | 1GH | Uncharacterized protein | / | 0.441 | |
| 4tzk | 641 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 5epe | SAH | Uncharacterized protein | / | 0.441 | |
| 3d4s | TIM | Beta-2 adrenergic receptor | / | 0.441 | |
| 1boz | PRD | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1dgh | NDP | Catalase | 1.11.1.6 | 0.440 | |
| 1djq | FMN | Trimethylamine dehydrogenase | 1.5.8.2 | 0.440 | |
| 1fnc | FDA | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.440 | |
| 1mdl | RMN | Mandelate racemase | / | 0.440 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1pr4 | MTP | Purine nucleoside phosphorylase DeoD-type | / | 0.440 | |
| 1thn | ADP | Anti-sigma F factor | / | 0.440 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.440 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 2b01 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.440 | |
| 2fhj | H4Z | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.440 | |
| 2fq6 | P3F | Cystathionine beta-lyase MetC | 4.4.1.8 | 0.440 | |
| 2jj2 | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.440 | |
| 2pdl | TOL | Aldose reductase | 1.1.1.21 | 0.440 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.440 | |
| 2vfz | UPF | N-acetyllactosaminide alpha-1,3-galactosyltransferase | / | 0.440 | |
| 2xnn | 430 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.440 | |
| 2yhu | WHF | Pteridine reductase | / | 0.440 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.440 | |
| 3hqd | ANP | Kinesin-like protein KIF11 | / | 0.440 | |
| 3ihg | VAK | Aklavinone 12-hydroxylase RdmE | / | 0.440 | |
| 3jq9 | AX1 | Pteridine reductase, putative | / | 0.440 | |
| 3jqb | DX6 | Pteridine reductase, putative | / | 0.440 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.440 | |
| 3w0u | HPW | Lactoylglutathione lyase | 4.4.1.5 | 0.440 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.440 | |
| 3zo7 | K6H | Muconolactone Delta-isomerase | / | 0.440 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.440 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 4bzn | UGX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 4cry | ACO | PanD regulatory factor | / | 0.440 | |
| 4flh | 14K | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4gkt | 0O1 | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.440 | |
| 4klr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.440 | |
| 4l17 | DNQ | Glutamate receptor 2 | / | 0.440 | |
| 4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.440 | |
| 4lsj | LSJ | Glucocorticoid receptor | / | 0.440 | |
| 4m6k | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4pxm | EST | Estrogen receptor | / | 0.440 | |
| 5d4v | YGP | Uncharacterized protein MJ0489 | / | 0.440 | |
| 4u16 | 3C0 | Muscarinic acetylcholine receptor M3 | / | 0.440 |