sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3zhz | FM7 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3zhz | FM7 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 1.000 | |
| 3owa | FAD | Acyl-CoA dehydrogenase | / | 0.466 | |
| 1yqx | NAP | Sinapyl alcohol dehydrogenase | / | 0.463 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.463 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.462 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.452 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.451 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.449 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.447 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.447 | |
| 2eba | FAD | Putative glutaryl-CoA dehydrogenase | / | 0.446 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.446 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.446 | |
| 1ydt | IQB | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 3fpz | AHZ | Thiamine thiazole synthase | / | 0.445 | |
| 3etd | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.444 | |
| 3g86 | T18 | Genome polyprotein | 2.7.7.48 | 0.444 | |
| 3qd4 | 3Q6 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 1qmz | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.443 | |
| 4mdh | NAD | Malate dehydrogenase, cytoplasmic | 1.1.1.37 | 0.443 | |
| 2vkm | BSD | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.442 | |
| 3zuy | TCH | Transporter | / | 0.442 | |
| 2b3d | FAD | Modulator of drug activity B | / | 0.441 | |
| 2vo7 | M05 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.440 |