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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3x2fNAIAdenosylhomocysteinase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3x2fNAIAdenosylhomocysteinase/1.000
2w3bNDPDihydrofolate reductase1.5.1.30.477
1e3eNAIAlcohol dehydrogenase 41.1.1.10.448
1tehNADAlcohol dehydrogenase class-31.1.1.10.447
3pvt3HC1,2-phenylacetyl-CoA epoxidase, subunit A1.14.13.1490.447
3bk2U5PRibonuclease J/0.444
5dozNDPJamJ/0.444
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.443
2xveFADPutative flavin-containing monooxygenase/0.443
1ma0NADAlcohol dehydrogenase class-31.1.1.10.440