sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 1.000 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.898 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.854 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.831 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.795 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.787 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.755 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.719 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.707 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.705 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.702 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.697 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.691 | |
| 2m56 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.690 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.689 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.689 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.685 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.685 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.684 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.684 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.682 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.682 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.678 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.676 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.675 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.673 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.670 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.669 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.664 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.663 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.662 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.660 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.660 | |
| 2zui | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.660 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.659 | |
| 2qbn | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.652 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.647 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.646 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.645 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.643 | |
| 2a1m | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.637 | |
| 2zaw | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.637 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.631 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.630 | |
| 4l4b | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.628 | |
| 2a1o | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.621 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.619 | |
| 1iwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.619 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.616 | |
| 4jx1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.611 | |
| 4l4a | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.608 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.606 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.602 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.597 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.593 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.592 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.559 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.543 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.542 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.540 | |
| 3p6n | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.538 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.533 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.532 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.530 | |
| 1rf9 | DBR | Camphor 5-monooxygenase | 1.14.15.1 | 0.522 | |
| 4c9o | CAM | Cytochrome P450 | / | 0.517 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.517 | |
| 2w0b | CMW | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.515 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.514 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.510 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.509 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.502 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.502 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.500 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.500 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.500 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.500 | |
| 1eup | ASD | 6-deoxyerythronolide B hydroxylase | / | 0.499 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.499 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.498 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.497 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.496 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.490 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.488 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.488 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.485 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.484 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.483 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.482 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.482 | |
| 2y3s | TIR | TamL | / | 0.481 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.480 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.480 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.479 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.477 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.477 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.477 | |
| 4fmx | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.477 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.473 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.472 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.472 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.472 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.472 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.472 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.472 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.471 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.471 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.471 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.470 | |
| 2y3r | TRK | TamL | / | 0.470 | |
| 3zuy | TCH | Transporter | / | 0.470 | |
| 2ca0 | PXI | Cytochrome P450 monooxygenase PikC | / | 0.469 | |
| 1suo | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.468 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.468 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.468 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.468 | |
| 1fml | RTL | Retinol dehydratase | / | 0.467 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.467 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.467 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.467 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.467 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.466 | |
| 2bi4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.465 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.465 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.465 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.464 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.464 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.464 | |
| 4n6h | EJ4 | Delta-type opioid receptor | / | 0.464 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.463 | |
| 3tnl | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.463 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.463 | |
| 2v9j | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.462 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.462 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.462 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.462 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.461 | |
| 1dyj | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.460 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.460 | |
| 3etg | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.460 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.459 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.459 | |
| 1bl6 | SB6 | Mitogen-activated protein kinase 14 | / | 0.458 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.458 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.458 | |
| 1rb2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 3g5h | YTT | Mycocyclosin synthase | 1.14.21.9 | 0.458 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.458 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.458 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.458 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.458 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.457 | |
| 3pe6 | ZYH | Monoglyceride lipase | / | 0.457 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.457 | |
| 2y4g | TIR | TamL | / | 0.456 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.456 | |
| 5a9s | NAP | Putative dehydrogenase | / | 0.456 | |
| 1dyh | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 3eej | 53R | Uncharacterized protein | / | 0.455 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.455 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.455 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.455 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 1hnc | GDN | Glutathione S-transferase Mu 2 | 2.5.1.18 | 0.454 | |
| 1svl | ADP | Large T antigen | 3.6.4 | 0.454 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 4ktl | 1CQ | Cytochrome P450 | / | 0.454 | |
| 4qq3 | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.454 | |
| 1zmc | NAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.453 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.453 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.453 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.452 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.452 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.452 | |
| 4lcg | 1WM | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.452 | |
| 1dds | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3eem | 53V | Uncharacterized protein | / | 0.451 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.451 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.451 | |
| 4a95 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.451 | |
| 4jlk | 1NO | Deoxycytidine kinase | 2.7.1.74 | 0.451 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.450 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.450 | |
| 2nnh | REA | Cytochrome P450 2C8 | / | 0.450 | |
| 3dt1 | P40 | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.450 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.450 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.450 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.450 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.449 | |
| 4dja | FAD | (6-4) photolyase | / | 0.449 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.449 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.448 | |
| 2wpx | ACO | Orf14 | / | 0.448 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.448 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.448 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.448 | |
| 3wec | AUI | Cytochrome P450 | / | 0.448 | |
| 4gav | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.448 | |
| 4jq9 | FAD | Dihydrolipoyl dehydrogenase | / | 0.448 | |
| 4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.448 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1rb3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 2ghl | LIB | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 2wqp | WQP | Polysialic acid capsule biosynthesis protein SiaC | / | 0.447 | |
| 3tjs | D0R | Cytochrome P450 3A4 | / | 0.447 | |
| 3w1t | WRO | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.447 | |
| 4egn | TWO | Cytochrome P450 | / | 0.447 | |
| 4ejh | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.447 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.447 | |
| 4oqy | NDP | (S)-imine reductase | / | 0.447 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 1dnp | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.446 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1zmd | NAI | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.446 | |
| 3a14 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.446 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.446 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.445 | |
| 1u3c | FAD | Cryptochrome-1 | / | 0.445 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.445 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.445 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.445 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 4a30 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.445 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.445 | |
| 4hw2 | 19H | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.445 | |
| 1dyi | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.444 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.444 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 2bl4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.444 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.444 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.444 | |
| 3cv9 | VDX | Vitamin D3 dihydroxylase | / | 0.444 | |
| 3hll | I45 | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3tvu | B37 | Acetyl-CoA carboxylase | / | 0.444 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.444 | |
| 4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.444 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.444 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.443 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.443 | |
| 1ddr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.443 | |
| 1t2b | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.443 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 3hek | BD0 | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 3ol5 | SAW | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.443 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.443 | |
| 5a3c | NAD | SIR2 family protein | / | 0.443 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.442 | |
| 2npx | NAD | NADH peroxidase | 1.11.1.1 | 0.442 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.442 | |
| 2w6z | L21 | Biotin carboxylase | 6.3.4.14 | 0.442 | |
| 3dds | 26B | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.442 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.442 | |
| 3p3e | 3P3 | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.442 | |
| 3rlr | 3RR | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 3uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.442 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.442 | |
| 4fk8 | FAD | Ferredoxin--NADP reductase | / | 0.442 | |
| 4hnc | 0UT | Mandelate racemase | / | 0.442 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.441 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.441 | |
| 2jcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.441 | |
| 2y3r | TIR | TamL | / | 0.441 | |
| 3ids | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.441 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.441 | |
| 3mk6 | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.441 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.441 | |
| 4g6g | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.441 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.441 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.441 | |
| 4z0h | NAD | Glyceraldehyde-3-phosphate dehydrogenase GAPC1, cytosolic | 1.2.1.12 | 0.441 | |
| 1aj8 | COA | Citrate synthase | / | 0.440 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.440 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.440 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.440 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.440 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.440 | |
| 3ekr | PY9 | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.440 | |
| 3p6o | ETG | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.440 | |
| 4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.440 | |
| 4ylf | FAD | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit homolog | / | 0.440 |