sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 1.000 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.907 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.834 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.832 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.770 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.764 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.709 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.698 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.697 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.690 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.686 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.685 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.683 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.679 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.678 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.675 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.675 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.670 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.665 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.664 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.662 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.661 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.661 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.660 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.658 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.658 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.657 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.656 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.655 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.655 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.653 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.650 | |
| 2a1o | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.649 | |
| 2a1m | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.648 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.641 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.639 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.639 | |
| 2m56 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.638 | |
| 2zui | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.635 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.634 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.634 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.630 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.627 | |
| 4jx1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.617 | |
| 4l4a | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.615 | |
| 1iwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.610 | |
| 2qbn | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.609 | |
| 2zaw | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.607 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.607 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.601 | |
| 4l4b | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.601 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.589 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.582 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.571 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.571 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.565 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.555 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.546 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.530 | |
| 3ol5 | SAW | Camphor 5-monooxygenase | 1.14.15.1 | 0.521 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.518 | |
| 1rf9 | DBR | Camphor 5-monooxygenase | 1.14.15.1 | 0.518 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.517 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.514 | |
| 4c9o | CAM | Cytochrome P450 | / | 0.514 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.512 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.505 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.495 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.490 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.486 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.483 | |
| 2w0b | CMW | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.482 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.482 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.481 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.479 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.476 | |
| 1t2b | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.475 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.474 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.473 | |
| 4fmx | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.472 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.471 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.470 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.467 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.461 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.460 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.459 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.458 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.457 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.457 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.457 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.457 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.455 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.455 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.454 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.454 | |
| 1eup | ASD | 6-deoxyerythronolide B hydroxylase | / | 0.452 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.452 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.452 | |
| 4ejh | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.452 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.451 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.450 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.449 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.449 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.448 | |
| 5bmv | VLB | Tubulin alpha-1B chain | / | 0.448 | |
| 5bmv | VLB | Tubulin beta chain | / | 0.448 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 1suo | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.446 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.446 | |
| 2y3r | TRK | TamL | / | 0.445 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.444 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.444 | |
| 2v9j | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.443 | |
| 3eej | 53R | Uncharacterized protein | / | 0.443 | |
| 3w1t | WRO | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.443 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 4qq3 | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.443 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.442 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.442 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 2nn7 | M29 | Carbonic anhydrase 1 | 4.2.1.1 | 0.440 |