sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3w3z | GTP | GTP-binding nuclear protein Ran |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3w3z | GTP | GTP-binding nuclear protein Ran | / | 1.000 | |
| 2x19 | GTP | GTP-binding nuclear protein GSP1/CNR1 | / | 0.558 | |
| 4ol0 | GTP | GTP-binding nuclear protein Ran | / | 0.533 | |
| 3a6p | GTP | GTP-binding nuclear protein Ran | / | 0.518 | |
| 3nbz | GTP | GTP-binding nuclear protein Ran | / | 0.518 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.507 | |
| 2gil | GTP | Ras-related protein Rab-6A | / | 0.504 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.497 | |
| 1yhn | GTP | Ras-related protein Rab-7a | / | 0.494 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.484 | |
| 5dha | GNP | GTP-binding nuclear protein Ran | / | 0.482 | |
| 1t91 | GTP | Ras-related protein Rab-7a | / | 0.480 | |
| 3bbp | GTP | Ras-related protein Rab-6A | / | 0.477 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.476 | |
| 5b2z | GNP | GTPase HRas | / | 0.475 | |
| 3ea5 | GDP | GTP-binding nuclear protein Ran | / | 0.474 | |
| 3law | GNP | Ras-related protein Rab-7a | / | 0.474 | |
| 3rab | GNP | Ras-related protein Rab-3A | / | 0.472 | |
| 1k5d | GNP | GTP-binding nuclear protein Ran | / | 0.469 | |
| 4k81 | GTP | GTPase HRas | / | 0.468 | |
| 4rkf | GNP | Ras-related protein Rab-3 | / | 0.468 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.466 | |
| 2bku | GTP | GTP-binding nuclear protein Ran | / | 0.465 | |
| 3oiv | GNP | GTPase HRas | / | 0.465 | |
| 1e96 | GTP | Ras-related C3 botulinum toxin substrate 1 | / | 0.464 | |
| 1ibr | GNP | GTP-binding nuclear protein Ran | / | 0.461 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.460 | |
| 3lbn | GNP | GTPase HRas | / | 0.460 | |
| 3sbd | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.460 | |
| 2zet | GTP | Ras-related protein Rab-27B | / | 0.458 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.456 | |
| 4o25 | GTP | GTP-binding protein Rheb | / | 0.456 | |
| 3pit | GNP | Ras-related protein M-Ras | / | 0.455 | |
| 3a58 | GNP | GTP-binding protein RHO1 | / | 0.454 | |
| 4dlt | GNP | GTPase HRas | / | 0.451 | |
| 1g17 | GNP | Ras-related protein SEC4 | / | 0.450 | |
| 2fe4 | GDP | Ras-related protein Rab-6B | / | 0.450 | |
| 2rgb | GNP | GTPase HRas | / | 0.450 | |
| 4mit | GTP | Rho-related protein racC | / | 0.450 | |
| 5jlj | GNP | GTP-binding nuclear protein Ran | / | 0.449 | |
| 1zd9 | GDP | ADP-ribosylation factor-like protein 8A | / | 0.447 | |
| 1vg8 | GNP | Ras-related protein Rab-7a | / | 0.446 | |
| 3kuc | GDP | Ras-related protein Rap-1A | / | 0.446 | |
| 3ddc | GNP | GTPase HRas | / | 0.442 | |
| 3l8y | GNP | GTPase HRas | / | 0.441 | |
| 3rs5 | GNP | GTPase HRas | / | 0.440 |