Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3w3dATPActin, gamma-enteric smooth muscle

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3w3dATPActin, gamma-enteric smooth muscle/1.000
1c0fATPMajor actin/0.617
4k42ADPActin, alpha skeletal muscle/0.616
1kxpATPActin, alpha skeletal muscle/0.605
4pkiATPActin, alpha skeletal muscle/0.601
1t44ATPActin, alpha skeletal muscle/0.598
3ffkATPActin, alpha skeletal muscle/0.597
3m6gATPActin, alpha skeletal muscle/0.597
4jhdANPActin-5C/0.594
1h1vATPActin, alpha skeletal muscle/0.592
3u9dATPActin, alpha skeletal muscle/0.592
1mduATPActin, alpha skeletal muscle/0.589
2q36ATPActin, alpha skeletal muscle/0.580
5ce3ATPActin/0.579
3m1fATPActin, alpha skeletal muscle/0.576
1lotATPActin, alpha skeletal muscle/0.575
3mn6ATPActin-5C/0.575
3el2ATPActin-5C/0.570
4cbxATPActin-2/0.570
1dejATPMajor actin/0.566
4pkhADPActin, alpha skeletal muscle/0.566
3tu5ATPActin, alpha skeletal muscle/0.564
1s22ATPActin, alpha skeletal muscle/0.563
4ci6ATPActin/0.559
1rgiATPActin, alpha skeletal muscle/0.557
1qz5ATPActin, alpha skeletal muscle/0.556
4m63ATPActin-5C/0.554
4pl8ATPActin, alpha skeletal muscle/0.546
2v51ATPActin, alpha skeletal muscle/0.545
3a5mATPMajor actin/0.545
1ijjATPActin, alpha skeletal muscle/0.542
1yxqATPActin, alpha skeletal muscle/0.536
2q97ATPActin, alpha skeletal muscle/0.535
4pkgATPActin, alpha skeletal muscle/0.532
3mn7ATPActin-5C/0.531
3mn9ATPActin-5C/0.531
3u4lATPActin, cytoplasmic 1/0.527
2a41ATPActin, alpha skeletal muscle/0.526
4k43ADPActin, alpha skeletal muscle/0.526
4k41ATPActin, alpha skeletal muscle/0.523
1eqyATPActin, alpha skeletal muscle/0.521
1nmdATPMajor actin/0.519
3a5oATPMajor actin/0.510
4rwtANPActin-5C/0.510
2p9kATPActin-related protein 2/0.502
1nm1ATPMajor actin/0.496
3eksATPActin-5C/0.493
3dawATPActin, alpha skeletal muscle/0.477
2oanATPActin, cytoplasmic 1/0.476
1rfqATPActin, alpha skeletal muscle/0.452