sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3vuz | K15 | Histone-lysine N-methyltransferase SETD7 | 2.1.1.43 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3vuz | K15 | Histone-lysine N-methyltransferase SETD7 | 2.1.1.43 | 1.000 | |
| 3vv0 | KH3 | Histone-lysine N-methyltransferase SETD7 | 2.1.1.43 | 0.615 | |
| 3vye | VYE | Renin | 3.4.23.15 | 0.506 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.489 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.489 | |
| 1yry | MSG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.487 | |
| 3d3x | ARG_ILE_MET_GLU_NH2 | Type E botulinum toxin | / | 0.486 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.486 | |
| 4bxk | 1IU | Angiotensin-converting enzyme | 3.2.1 | 0.486 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.485 | |
| 3cid | 318 | Beta-secretase 1 | 3.4.23.46 | 0.484 | |
| 4lxa | 1YS | Beta-secretase 1 | 3.4.23.46 | 0.484 | |
| 4ewo | 996 | Beta-secretase 1 | 3.4.23.46 | 0.483 | |
| 2x92 | X92 | Angiotensin-converting enzyme | 3.4.15.1 | 0.482 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.481 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.481 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.480 | |
| 3veu | 0GO | Beta-secretase 1 | 3.4.23.46 | 0.479 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.478 | |
| 3udn | 09B | Beta-secretase 1 | 3.4.23.46 | 0.478 | |
| 2b3v | ACO | Diamine acetyltransferase 1 | / | 0.477 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.477 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.477 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.477 | |
| 4blr | UTP | NTPase P4 | / | 0.477 | |
| 2viy | VG3 | Beta-secretase 1 | 3.4.23.46 | 0.476 | |
| 4nv1 | 4TG | Formyl transferase | / | 0.476 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.476 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.475 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.475 | |
| 3vg1 | 0GT | Beta-secretase 1 | 3.4.23.46 | 0.475 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.475 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.475 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.475 | |
| 2ntr | L00 | Beta-secretase 1 | 3.4.23.46 | 0.474 | |
| 3k5c | 0BI | Beta-secretase 1 | 3.4.23.46 | 0.474 | |
| 3pi5 | 3P5 | Beta-secretase 1 | 3.4.23.46 | 0.474 | |
| 3r2f | PB0 | Beta-secretase 1 | 3.4.23.46 | 0.474 | |
| 4gid | 0GH | Beta-secretase 1 | 3.4.23.46 | 0.474 | |
| 5dp2 | NAP | CurF | / | 0.474 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.473 | |
| 3dv5 | BAV | Beta-secretase 1 | 3.4.23.46 | 0.473 | |
| 3lzs | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.473 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.473 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.473 | |
| 3vuc | HHE | Renin | 3.4.23.15 | 0.473 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.472 | |
| 2irz | I02 | Beta-secretase 1 | 3.4.23.46 | 0.472 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.472 | |
| 3vsx | R32 | Renin | 3.4.23.15 | 0.472 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.472 | |
| 1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.471 | |
| 2oah | QIN | Beta-secretase 1 | 3.4.23.46 | 0.471 | |
| 3int | FDA | UDP-galactopyranose mutase | 5.4.99.9 | 0.471 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.471 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.471 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.470 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.470 | |
| 4i0h | 1BL | Beta-secretase 1 | 3.4.23.46 | 0.470 | |
| 4nv1 | 0FX | Formyl transferase | / | 0.470 | |
| 5ch7 | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.470 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.469 | |
| 3k5f | AYH | Beta-secretase 1 | 3.4.23.46 | 0.469 | |
| 2fut | H1S | Heparin and heparin-sulfate lyase | / | 0.468 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.468 | |
| 3skg | PB8 | Beta-secretase 1 | 3.4.23.46 | 0.468 | |
| 1amo | FMN | NADPH--cytochrome P450 reductase | / | 0.467 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.467 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.467 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.467 | |
| 3uax | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.467 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.467 | |
| 5jj0 | SAM | Histone-lysine N-methyltransferase EHMT2 | / | 0.467 | |
| 1t57 | FMN | Conserved protein | / | 0.466 | |
| 2vnn | CM7 | Beta-secretase 1 | 3.4.23.46 | 0.466 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.466 | |
| 3up0 | D7S | aceDAF-12 | / | 0.466 | |
| 3vf3 | 0GS | Beta-secretase 1 | 3.4.23.46 | 0.466 | |
| 1tiq | COA | Spermidine/spermine N(1)-acetyltransferase | / | 0.465 | |
| 2b8l | 5HA | Beta-secretase 1 | 3.4.23.46 | 0.465 | |
| 2cmf | F11 | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 2f3e | AXQ | Beta-secretase 1 | 3.4.23.46 | 0.465 | |
| 2hiz | LIJ | Beta-secretase 1 | 3.4.23.46 | 0.465 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.465 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.465 | |
| 3duy | AFJ | Beta-secretase 1 | 3.4.23.46 | 0.465 | |
| 3dv1 | AR9 | Beta-secretase 1 | 3.4.23.46 | 0.465 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.464 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.464 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.464 | |
| 4k9h | 1QU | Beta-secretase 1 | 3.4.23.46 | 0.464 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.463 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.463 | |
| 2a2d | ANP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.463 | |
| 2vij | C44 | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.463 | |
| 3vx4 | ATP | Putative ABC transporter, ATP-binding protein ComA | / | 0.463 | |
| 4eqs | COA | Coenzyme A disulfide reductase | / | 0.463 | |
| 1v5y | 4HC | Major NAD(P)H-flavin oxidoreductase | 1.6.99 | 0.462 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.462 | |
| 2iqg | F2I | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 2x95 | X95 | Angiotensin-converting enzyme | 3.4.15.1 | 0.462 | |
| 3ixk | 929 | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 4d89 | BXD | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 1opm | IYG | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.461 | |
| 4e32 | DWN | Methyltransferase | / | 0.461 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.460 | |
| 1v0j | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.460 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.460 | |
| 2wf4 | ZY4 | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 4lxk | 1YT | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.460 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.460 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.459 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.459 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.459 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.459 | |
| 2hm1 | LIQ | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 2qrq | S13 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.459 | |
| 2wez | ZYE | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 3buv | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.459 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.459 | |
| 3udj | 092 | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 3utg | FDA | UDP-galactopyranose mutase | / | 0.459 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.459 | |
| 4dpi | 0N1 | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.458 | |
| 2wf2 | ZY2 | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.458 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.458 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 3k5d | XLI | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.458 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.458 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.458 | |
| 4exg | 916 | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 5epo | TUD | 7-alpha-hydroxysteroid deydrogenase | / | 0.458 | |
| 4b65 | FAD | L-ornithine N(5)-monooxygenase | / | 0.457 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.457 | |
| 4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.457 | |
| 4tlz | FAD | KtzI | / | 0.457 | |
| 2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.456 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.456 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.456 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.455 | |
| 1w4x | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.455 | |
| 1wwz | ACO | Uncharacterized protein | / | 0.455 | |
| 2bn4 | FMN | NADPH--cytochrome P450 reductase | / | 0.455 | |
| 2wf3 | ZY3 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 3ixj | 586 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.455 | |
| 3ufl | 508 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.455 | |
| 4e2z | JHZ | Methyltransferase | / | 0.455 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.455 | |
| 1fap | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.454 | |
| 1fap | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.454 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.454 | |
| 2fiw | ACO | GCN5-related N-acetyltransferase:Aminotransferase, class-II | / | 0.454 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.454 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.454 | |
| 2ph6 | 712 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.454 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.454 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.454 | |
| 3m4p | 4AD | Asparaginyl-tRNA synthetase, putative | / | 0.454 | |
| 3udk | 095 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4fse | 0VA | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.454 | |
| 4gsu | DWZ | L,D-transpeptidase 2 | 2.3.2 | 0.454 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.454 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.454 | |
| 1bdu | DUR | Thymidylate synthase | / | 0.453 | |
| 1hbv | GAN | Gag-Pol polyprotein | / | 0.453 | |
| 1mv8 | GDX | GDP-mannose 6-dehydrogenase | 1.1.1.132 | 0.453 | |
| 1n6c | SAM | Histone-lysine N-methyltransferase SETD7 | 2.1.1.43 | 0.453 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.453 | |
| 2ien | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 2v13 | C40 | Renin | 3.4.23.15 | 0.453 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.453 | |
| 1k4m | NAD | Nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.452 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.452 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.452 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.452 | |
| 3dm6 | 757 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 3qbh | QBH | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 4dpf | 0LG | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 4kb9 | G79 | Protease | / | 0.452 | |
| 4mo2 | FAD | UDP-galactopyranose mutase | / | 0.452 | |
| 2is0 | I03 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.451 | |
| 2r8o | T5X | Transketolase 1 | / | 0.451 | |
| 3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.451 | |
| 3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.451 | |
| 3rfa | SAM | Dual-specificity RNA methyltransferase RlmN | / | 0.451 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.451 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.450 | |
| 2ph8 | 35A | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.450 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.450 | |
| 3eks | CY9 | Actin-5C | / | 0.450 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.450 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.450 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.450 | |
| 4rvf | TYD | D-mycarose 3-C-methyltransferase | / | 0.450 | |
| 4tm4 | FDA | KtzI | / | 0.450 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.450 | |
| 2vj6 | VG5 | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3nxq | RX4 | Angiotensin-converting enzyme | 3.2.1 | 0.449 | |
| 3ohf | 3HF | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 3tog | 079 | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 4k8s | 1QT | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4tlx | FDA | KtzI | / | 0.449 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.448 | |
| 1k9s | FM1 | Purine nucleoside phosphorylase DeoD-type | / | 0.448 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.448 | |
| 2wf1 | ZY1 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.448 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.448 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.448 | |
| 4iv6 | FDA | Isovaleryl-CoA dehydrogenase | / | 0.448 | |
| 4yvz | 3AT | DNA integrity scanning protein DisA | / | 0.448 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.447 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.447 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.447 | |
| 2wf0 | ZY0 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 2z54 | AB1 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 3cb2 | GDP | Tubulin gamma-1 chain | / | 0.447 | |
| 3g0b | T22 | Dipeptidyl peptidase 4 | / | 0.447 | |
| 3ihk | TPP | Uncharacterized protein | / | 0.447 | |
| 3o2x | 3O2 | Collagenase 3 | 3.4.24 | 0.447 | |
| 3sgl | FAD | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | / | 0.447 | |
| 4cf6 | CBD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.446 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.446 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.446 | |
| 2bi7 | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.446 | |
| 2bqz | SAH | N-lysine methyltransferase KMT5A | / | 0.446 | |
| 2c1z | U2F | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.446 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.446 | |
| 2p4j | 23I | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 2q15 | 3MR | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3em3 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 3ukf | FDA | UDP-galactopyranose mutase | / | 0.446 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.446 | |
| 5a01 | 12V | O-glycosyltransferase | / | 0.446 | |
| 5cku | FAD | L-ornithine N(5)-monooxygenase | / | 0.446 | |
| 1cdo | NAD | Alcohol dehydrogenase 1 | 1.1.1.1 | 0.445 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.445 | |
| 1ve3 | SAM | Uncharacterized protein | / | 0.445 | |
| 2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.445 | |
| 2ohj | FMN | Type A flavoprotein FprA | 1 | 0.445 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.445 | |
| 3l5e | BDW | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4fsl | 0VB | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4gde | FDA | UDP-galactopyranose mutase | / | 0.445 | |
| 4tm1 | FDA | KtzI | / | 0.445 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.445 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 1jcq | 739 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.444 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.444 | |
| 1qx4 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.444 | |
| 2f81 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.444 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.444 | |
| 3gf4 | UPG | UDP-galactopyranose mutase | 5.4.99.9 | 0.444 | |
| 3n71 | SFG | Histone-lysine N-methyltransferase Smyd1 | / | 0.444 | |
| 3w8w | FAD | Putative FAD-dependent oxygenase EncM | / | 0.444 | |
| 4b63 | FAD | L-ornithine N(5)-monooxygenase | / | 0.444 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.444 | |
| 4e2y | JHZ | Methyltransferase | / | 0.444 | |
| 4frs | 0V6 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4g5d | NDP | Prostaglandin F synthase | 1.1.1.188 | 0.444 | |
| 4y0k | NAP | AntE | / | 0.444 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.443 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.443 | |
| 2g94 | ZPQ | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 2qzl | IXS | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.443 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.443 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.443 | |
| 3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3gwd | NAP | Cyclohexanone monooxygenase | / | 0.443 | |
| 3kmx | G00 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3mtw | M3R | Xaa-Pro dipeptidase, putative | / | 0.443 | |
| 4brg | GNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.443 | |
| 4h3i | 10V | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4j4n | D44 | Peptidylprolyl isomerase | / | 0.443 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.443 | |
| 4l7g | 1W0 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4u8m | FDA | UDP-galactopyranose mutase | / | 0.443 | |
| 4yxm | 2BA | DNA integrity scanning protein DisA | / | 0.443 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.443 | |
| 1j36 | LPR | Angiotensin-converting enzyme | 3.4.15.1 | 0.442 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.442 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 2xy3 | DUP | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.442 | |
| 3g0g | RUM | Dipeptidyl peptidase 4 | / | 0.442 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.442 | |
| 3rup | ADP | Biotin carboxylase | 6.3.4.14 | 0.442 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.442 | |
| 4b66 | FAD | L-ornithine N(5)-monooxygenase | / | 0.442 | |
| 4b68 | FAD | L-ornithine N(5)-monooxygenase | / | 0.442 | |
| 4e47 | 0N6 | Histone-lysine N-methyltransferase SETD7 | 2.1.1.43 | 0.442 | |
| 4h3f | 10O | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4wx1 | FDA | UDP-galactopyranose mutase | / | 0.442 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.442 | |
| 1e1c | DCA | Methylmalonyl-CoA mutase large subunit | 5.4.99.2 | 0.441 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 1ja1 | FMN | NADPH--cytochrome P450 reductase | / | 0.441 | |
| 1k4q | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.441 | |
| 1sdw | IYT | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.441 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.441 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.441 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.441 | |
| 2c27 | MA8 | Mycothiol acetyltransferase | 2.3.1.189 | 0.441 | |
| 2p3b | 3TL | V-1 PROTEASE protein | / | 0.441 | |
| 2p3b | 3TL | V-1 protease | / | 0.441 | |
| 3fhy | ATP | Pyridoxal kinase | 2.7.1.35 | 0.441 | |
| 3k5g | BJC | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3kmy | D8Y | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3lzx | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.441 | |
| 3m0o | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.441 | |
| 3ukk | FAD | UDP-galactopyranose mutase | / | 0.441 | |
| 4bqu | CLR | Japanin | / | 0.441 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.441 | |
| 4lrl | TTP | HD domain protein | / | 0.441 | |
| 1cne | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.440 | |
| 1jzs | MRC | Isoleucine--tRNA ligase | 6.1.1.5 | 0.440 | |
| 1vik | BAY | Gag-Pol polyprotein | / | 0.440 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.440 | |
| 1ye6 | NAP | NAD(P)H-dependent D-xylose reductase | 1.1.1.307 | 0.440 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.440 | |
| 2h21 | SAM | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.440 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.440 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.440 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.440 | |
| 3mj4 | FAD | UDP-galactopyranose mutase | / | 0.440 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.440 | |
| 3ukf | GDU | UDP-galactopyranose mutase | / | 0.440 | |
| 4fkz | UD1 | UDP-N-acetylglucosamine 2-epimerase | 5.1.3.14 | 0.440 | |
| 4nes | UD1 | UDP-N-acetylglucosamine 2-epimerase | 5.1.3.14 | 0.440 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.440 |