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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3vryB43Tyrosine-protein kinase HCK2.7.10.2

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3vryB43Tyrosine-protein kinase HCK2.7.10.21.000
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.648
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.645
3vs3VSETyrosine-protein kinase HCK2.7.10.20.640
2c0tL3GTyrosine-protein kinase HCK2.7.10.20.627
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.627
2c0iL1GTyrosine-protein kinase HCK2.7.10.20.611
3vs0VS0Tyrosine-protein kinase HCK2.7.10.20.611
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.604
2c0oL2GTyrosine-protein kinase HCK2.7.10.20.602
3vs1VSATyrosine-protein kinase HCK2.7.10.20.602
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.601
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.598
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.597
3bbtFMMReceptor tyrosine-protein kinase erbB-42.7.10.10.592
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.591
4dggI76Proto-oncogene tyrosine-protein kinase Src2.7.10.20.591
3qlfPD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.589
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.570
4i22IREEpidermal growth factor receptor2.7.10.10.553
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.548
4hjoAQ4Epidermal growth factor receptor2.7.10.10.546
4nka2K7Fibroblast growth factor receptor 1/0.545
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.540
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.540
3w33W19Epidermal growth factor receptor2.7.10.10.535
1xkkFMMEpidermal growth factor receptor2.7.10.10.534
4otwDB8Receptor tyrosine-protein kinase erbB-32.7.10.10.532
3w2sW2REpidermal growth factor receptor2.7.10.10.527
1ad5ANPTyrosine-protein kinase HCK2.7.10.20.526
2of2547Tyrosine-protein kinase Lck2.7.10.20.526
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.525
1bygSTUTyrosine-protein kinase CSK/0.523
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.523
2hk51BMTyrosine-protein kinase HCK2.7.10.20.522
4yuqKS1Calmodulin-like domain protein kinase/0.522
2zva1N1Tyrosine-protein kinase Lyn2.7.10.20.521
5e8wSTUTGF-beta receptor type-12.7.11.300.516
1u4dDBQActivated CDC42 kinase 1/0.515
1yolS03Proto-oncogene tyrosine-protein kinase Src2.7.10.20.515
2wotZZGTGF-beta receptor type-12.7.11.300.515
4lgh0JNProto-oncogene tyrosine-protein kinase Src2.7.10.20.514
2zm1KSFTyrosine-protein kinase Lck2.7.10.20.513
3poz03PEpidermal growth factor receptor2.7.10.10.513
4gk2L66Ephrin type-A receptor 32.7.10.10.507
4riyADPEpidermal growth factor receptor2.7.10.10.507
3r9dX6BCyclin-dependent kinase 22.7.11.220.505
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.504
3mtfA3FActivin receptor type-12.7.11.300.502
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.502
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.501
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.501
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.501
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.500
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.499
4gk4L90Ephrin type-A receptor 32.7.10.10.499
4gmy0X5Tyrosine-protein kinase JAK2/0.499
1rw8580TGF-beta receptor type-12.7.11.300.498
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.498
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.498
2zv9PP2Tyrosine-protein kinase Lyn2.7.10.20.497
3gxlQIGTGF-beta receptor type-12.7.11.300.497
3uvqFS8Mitogen-activated protein kinase 14/0.497
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.496
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.496
3l8p0CEAngiopoietin-1 receptor2.7.10.10.496
5aaaVGHALK tyrosine kinase receptor2.7.10.10.495
1vjy460TGF-beta receptor type-12.7.11.300.494
1u54ACPActivated CDC42 kinase 1/0.493
4mxoDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.493
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.493
4c02TAKActivin receptor type-12.7.11.300.492
4g170VNCasein kinase I isoform gamma-32.7.11.10.492
3b2w9NHTyrosine-protein kinase Lck2.7.10.20.491
4hvi19STyrosine-protein kinase JAK32.7.10.20.491
2x2lX2LProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.490
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.490
4hvh19RTyrosine-protein kinase JAK32.7.10.20.490
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.489
3aoxEMHALK tyrosine kinase receptor2.7.10.10.489
4bb432WEphrin type-B receptor 42.7.10.10.489
4kiq1RAMitogen-activated protein kinase 14/0.489
4fic0ULProto-oncogene tyrosine-protein kinase Src2.7.10.20.488
2itnANPEpidermal growth factor receptor2.7.10.10.487
2itqITQEpidermal growth factor receptor2.7.10.10.487
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.487
3ac5KZMTyrosine-protein kinase Lck2.7.10.20.487
3w18N13Aurora kinase A2.7.11.10.487
4j97ACPFibroblast growth factor receptor 2/0.487
2qo9ANPEphrin type-A receptor 32.7.10.10.486
4lggVGGProto-oncogene tyrosine-protein kinase Src2.7.10.20.486
2vwz7X6Ephrin type-B receptor 42.7.10.10.485
4mcv29KProto-oncogene tyrosine-protein kinase Src2.7.10.20.485
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.485
4mxyDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.485
4mxzDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.485
2c6eHPMAurora kinase A2.7.11.10.484
5e8xSTUTGF-beta receptor type-12.7.11.300.484
2vx17X8Ephrin type-B receptor 42.7.10.10.483
3oom507Activin receptor type-12.7.11.300.483
4id71G0Activated CDC42 kinase 1/0.483
4jq8KJ8Epidermal growth factor receptor2.7.10.10.483
4xey1N1Tyrosine-protein kinase ABL12.7.10.20.483
2vwx7X4Ephrin type-B receptor 42.7.10.10.482
5amnDTQProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.482
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.481
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.481
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.481
4ih8B43Calmodulin-domain protein kinase 1/0.481
1m17AQ4Epidermal growth factor receptor2.7.10.10.480
2ivvPP1Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.480
2vwu7X1Ephrin type-B receptor 42.7.10.10.480
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.480
3qlg1N1Proto-oncogene tyrosine-protein kinase Src2.7.10.20.480
4c62XWWTyrosine-protein kinase JAK2/0.480
4gk3L87Ephrin type-A receptor 32.7.10.10.480
4hvg19QTyrosine-protein kinase JAK32.7.10.20.480
3w32W32Epidermal growth factor receptor2.7.10.10.479
4btkDTQTau-tubulin kinase 12.7.11.10.479
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.479
2henADPEphrin type-B receptor 22.7.10.10.478
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.478
4c4h7RODual specificity protein kinase TTK2.7.12.10.478
3ac2KSETyrosine-protein kinase Lck2.7.10.20.477
3ad6KSCTyrosine-protein kinase Lck2.7.10.20.477
3gubGUBDeath-associated protein kinase 12.7.11.10.477
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.477
1jpaANPEphrin type-B receptor 22.7.10.10.476
2yiqYIQSerine/threonine-protein kinase Chk22.7.11.10.476
4dymIYZActivin receptor type-12.7.11.300.476
1qpePP2Tyrosine-protein kinase Lck2.7.10.20.475
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.475
4nk92K5Fibroblast growth factor receptor 1/0.475
3dtcVINMitogen-activated protein kinase kinase kinase 92.7.11.250.474
3hmm855TGF-beta receptor type-12.7.11.300.474
3v5j0F2Tyrosine-protein kinase ITK/TSK2.7.10.20.474
4nks2M2Fibroblast growth factor receptor 1/0.474
1xddAAYIntegrin alpha-L/0.473
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.473
2gs7ANPEpidermal growth factor receptor2.7.10.10.473
3js2VM1Fibroblast growth factor receptor 1/0.473
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.473
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.473
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.472
4idv13VMitogen-activated protein kinase kinase kinase 142.7.11.250.472
2vwy7X5Ephrin type-B receptor 42.7.10.10.471
3mvl38PMitogen-activated protein kinase 14/0.471
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.471
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.470
2pzpACPFibroblast growth factor receptor 2/0.470
3ac3KSHTyrosine-protein kinase Lck2.7.10.20.470
4c4g7RODual specificity protein kinase TTK2.7.12.10.470
4yt5H4MH(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338/0.470
2p2h994Vascular endothelial growth factor receptor 22.7.10.10.469
2x2kX2KProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.469
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.469
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.469
4aa4QC0Mitogen-activated protein kinase 14/0.468
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.468
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.468
4jr3KJREpidermal growth factor receptor2.7.10.10.468
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.468
1ie4T44Transthyretin/0.467
2zybKSLTyrosine-protein kinase Lck2.7.10.20.467
3el8PD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.467
3w2rW2REpidermal growth factor receptor2.7.10.10.467
3zdiUGJGlycogen synthase kinase-3 beta2.7.11.260.467
4g2fC07Ephrin type-A receptor 32.7.10.10.467
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.466
2pz5ACPFibroblast growth factor receptor 2/0.466
2wecPP5Penicillopepsin-13.4.23.200.466
3a60STURibosomal protein S6 kinase beta-12.7.11.10.466
3gc9B45Mitogen-activated protein kinase 112.7.11.240.466
2py3ACPFibroblast growth factor receptor 2/0.465
2xa4AZ5Tyrosine-protein kinase JAK2/0.465
2xyuQ9GEphrin type-A receptor 42.7.10.10.465
3ds6A17Mitogen-activated protein kinase 14/0.465
3ttjJBIMitogen-activated protein kinase 102.7.11.240.465
1c6yMK1Protease/0.464
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.464
2om9AJAPeroxisome proliferator-activated receptor gamma/0.464
2xvdAS6Ephrin type-B receptor 42.7.10.10.464
2yn8STUEphrin type-B receptor 42.7.10.10.464
4c4iX20Dual specificity protein kinase TTK2.7.12.10.464
4xli1N1Abelson tyrosine-protein kinase 22.7.10.20.464
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.463
4a6bQG8Gag-Pol polyprotein3.4.23.160.463
4dfl0K0Tyrosine-protein kinase SYK2.7.10.20.463
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.463
4jboWPHAurora kinase A2.7.11.10.463
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.463
4kip1R9Mitogen-activated protein kinase 14/0.463
1xjdSTUProtein kinase C theta type2.7.11.130.462
2fgiPD1Fibroblast growth factor receptor 1/0.462
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.462
2itzIREEpidermal growth factor receptor2.7.10.10.461
2v7a627Tyrosine-protein kinase ABL12.7.10.20.461
2vww7X2Ephrin type-B receptor 42.7.10.10.461
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.461
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.461
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
3zewSTUEphrin type-B receptor 42.7.10.10.461
4aotGW8Serine/threonine-protein kinase 102.7.11.10.461
4c61LMMTyrosine-protein kinase JAK2/0.461
4e4m0NHTyrosine-protein kinase JAK2/0.461
1sm2STUTyrosine-protein kinase ITK/TSK2.7.10.20.460
2ittAEEEpidermal growth factor receptor2.7.10.10.460
2of4979Tyrosine-protein kinase Lck2.7.10.20.460
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.460
4bdbODOSerine/threonine-protein kinase Chk22.7.11.10.460
2pwlACPFibroblast growth factor receptor 2/0.459
2qo7ANPEphrin type-A receptor 32.7.10.10.459
2xp2VGHALK tyrosine kinase receptor2.7.10.10.459
3h0aD30Peroxisome proliferator-activated receptor gamma/0.459
3icrCOACoenzyme A disulfide reductase/0.459
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.459
4ic7ANPMitogen-activated protein kinase 72.7.11.240.459
4wkqIREEpidermal growth factor receptor2.7.10.10.459
1pnvTYDdTDP-epi-vancosaminyltransferase2.4.1.3110.458
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.458
3hllI45Mitogen-activated protein kinase 14/0.458
4jayFADUDP-N-acetylenolpyruvoylglucosamine reductase/0.458
4jia1K3Tyrosine-protein kinase JAK2/0.458
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.458
1py5PY1TGF-beta receptor type-12.7.11.300.457
2c3qGTXGlutathione S-transferase theta-12.5.1.180.457
2qocANPEphrin type-A receptor 32.7.10.10.457
2wouZZFTGF-beta receptor type-12.7.11.300.457
2y6o1N1Ephrin type-A receptor 42.7.10.10.457
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.457
3slkNDPPolyketide synthase extender module 2/0.457
4erwSTUCyclin-dependent kinase 22.7.11.220.457
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
4jvb1M0Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.457
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.457
2excJNKMitogen-activated protein kinase 102.7.11.240.456
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.456
3nbvANPKetohexokinase/0.456
3r9hZ67Cyclin-dependent kinase 22.7.11.220.456
5e92ANPTGF-beta receptor type-22.7.11.300.456
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.455
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
3jy0LYGSerine/threonine-protein kinase pim-12.7.11.10.455
3q4zANPSerine/threonine-protein kinase PAK 12.7.11.10.455
3s4qNK0Mitogen-activated protein kinase 14/0.455
3upjU03Gag-Pol polyprotein/0.455
4aa5NQBMitogen-activated protein kinase 14/0.455
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.455
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.455
4hgs15GCasein kinase I isoform gamma-32.7.11.10.455
4jbqVX6Aurora kinase A2.7.11.10.455
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.455
4mcb21WtRNA (guanine-N(1)-)-methyltransferase2.1.1.2280.455
1i8tFADUDP-galactopyranose mutase5.4.99.90.454
2uy0HV1Gag-Pol polyprotein3.4.23.160.454
2uzlC94Cyclin-dependent kinase 22.7.11.220.454
2yaaATPDeath-associated protein kinase 2/0.454
2zm4KSMTyrosine-protein kinase Lck2.7.10.20.454
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.454
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.454
3nbwTR4Ketohexokinase/0.454
3v3vMYUMitogen-activated protein kinase 82.7.11.240.454
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.454
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.454
4nj32KDCyclin-dependent kinase 22.7.11.220.454
4pd6URINucleoside permease/0.454
1pn3TYDdTDP-epi-vancosaminyltransferase2.4.1.3110.453
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.453
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
2p4yC03Peroxisome proliferator-activated receptor gamma/0.453
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.453
3iphG11Mitogen-activated protein kinase 14/0.453
3mg3ECHOrange carotenoid-binding protein/0.453
4bb5HD2Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.453
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.453
4l2iFADElectron transfer flavoprotein alpha/beta-subunit/0.453
4qmpDKISerine/threonine-protein kinase 242.7.11.10.453
5bvw1N1Epithelial discoidin domain-containing receptor 12.7.10.10.453
2izrBRKCasein kinase I isoform gamma-32.7.11.10.452
2xikJ60Serine/threonine-protein kinase 252.7.11.10.452
3b2tM33Fibroblast growth factor receptor 2/0.452
3fskRO6Mitogen-activated protein kinase 14/0.452
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.452
3tmz06XCytochrome P450 2B41.14.14.10.452
4ejn0R4RAC-alpha serine/threonine-protein kinase2.7.11.10.452
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
1jld0PPGag-Pol polyprotein/0.451
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.451
2h96893Mitogen-activated protein kinase 82.7.11.240.451
2jd0NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.451
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.451
2vx07X7Ephrin type-B receptor 42.7.10.10.451
2yfxVGHALK tyrosine kinase receptor2.7.10.10.451
2yyiFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.451
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.451
3mwuBK3Calmodulin-domain protein kinase 1, putative/0.451
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
3ttiKBIMitogen-activated protein kinase 102.7.11.240.451
4ansVGHALK tyrosine kinase receptor2.7.10.10.451
4aw530KEphrin type-B receptor 42.7.10.10.451
4g3e0WCMitogen-activated protein kinase kinase kinase 142.7.11.250.451
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.451
4kzoNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.451
2balPQAMitogen-activated protein kinase 14/0.450
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
2i1m5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.450
2itpAEEEpidermal growth factor receptor2.7.10.10.450
2x2mX2MProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.450
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.450
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.450
3l8xN4DMitogen-activated protein kinase 14/0.450
3sp6IL2Peroxisome proliferator-activated receptor alpha/0.450
3wmxNADNAD dependent epimerase/dehydratase/0.450
4aacAAVMitogen-activated protein kinase 14/0.450
4bc6XZNSerine/threonine-protein kinase 102.7.11.10.450
4g160VMCasein kinase I isoform gamma-32.7.11.10.450
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.450
4h3c0YZDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.450
5dr9SKEAurora kinase A2.7.11.10.450
1ebk0Q4Gag-Pol polyprotein3.4.23.160.449
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
1wbk568Pol protein/0.449
2izsBRQCasein kinase I isoform gamma-32.7.11.10.449
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.449
3bgrT27Gag-Pol polyprotein2.7.7.490.449
3ogqAB1Pol polyprotein/0.449
3t8oATPRhodopsin kinase/0.449
4f630S7Fibroblast growth factor receptor 1/0.449
4fnyI3KALK tyrosine kinase receptor2.7.10.10.449
4g310WHEukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.449
4jq7KJQEpidermal growth factor receptor2.7.10.10.449
4oavACP2-5A-dependent ribonuclease3.1.260.449
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.449
5k2aZMAAdenosine receptor A2a/0.449
1di8DTQCyclin-dependent kinase 22.7.11.220.448
1hiiC20Gag-Pol polyprotein/0.448
1xq6NAPUncharacterized protein At5g02240/0.448
1zmcNADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.448
2cig1DGDihydrofolate reductase1.5.1.30.448
2i40BLZCyclin-dependent kinase 22.7.11.220.448
2xynVX6Abelson tyrosine-protein kinase 22.7.10.20.448
3c7qXINVascular endothelial growth factor receptor 22.7.10.10.448
3dcrKVSProtease/0.448
3kddJZQGag-Pol polyprotein3.4.23.160.448
4djpM73Pol polyprotein/0.448
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.448
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.448
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.448
4jvf17XRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.448
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.448
3qakUKAAdenosine receptor A2a/0.448
2k62ITLFatty acid-binding protein, liver/0.447
2x9fX9FEphrin type-B receptor 42.7.10.10.447
2xyeCXGGag-Pol polyprotein/0.447
3gggNADPrephenate dehydrogenase/0.447
3linE13Protease/0.447
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.447
4bdgP3JSerine/threonine-protein kinase Chk22.7.11.10.447
4ewhT77Activated CDC42 kinase 1/0.447
4f640S8Fibroblast growth factor receptor 1/0.447
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.447
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.447
4y8wSTRSteroid 21-hydroxylase/0.447
4ysjADPCalmodulin-like domain protein kinase/0.447
1k6vXN2Gag-Pol polyprotein3.4.23.160.446
2c475IDCasein kinase I isoform gamma-2/0.446
2g2fAGSTyrosine-protein kinase ABL12.7.10.20.446
2hog710Serine/threonine-protein kinase Chk12.7.11.10.446
2ykiYKIHeat shock protein HSP 90-alpha/0.446
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
3opdHIEHeat shock protein 83/0.446
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.446
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.446
1gih1PUCyclin-dependent kinase 22.7.11.220.445
1yb5NAPQuinone oxidoreductase1.6.5.50.445
2q4bNAPUncharacterized protein At5g02240/0.445
2y46MIVMycinamicin IV hydroxylase/epoxidase/0.445
3fklFKLMitogen-activated protein kinase 14/0.445
3hx4ANPCalmodulin-domain protein kinase 1/0.445
3qa2XNAKetohexokinase/0.445
3s43478Protease/0.445
4bbfO19Tyrosine-protein kinase JAK2/0.445
4f650S9Fibroblast growth factor receptor 1/0.445
4hni16WCasein kinase I isoform epsilon2.7.11.10.445
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.445
5d12G97Proto-oncogene tyrosine-protein kinase Src2.7.10.20.445
1bdrIM1Gag-Pol polyprotein3.4.23.160.444
1cm8ANPMitogen-activated protein kinase 12/0.444
1gqtACPRibokinase/0.444
1hosPHPGag-Pol polyprotein/0.444
1mesDMPGag-Pol polyprotein3.4.23.160.444
1q0qNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.444
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.444
2fdd385Pol protein/0.444
2igoFADPyranose 2-oxidase/0.444
2vrx447Aurora kinase B-A2.7.11.10.444
2zb0GK3Mitogen-activated protein kinase 14/0.444
3cqeP91Wee1-like protein kinase2.7.10.20.444
3sacAF8Protease/0.444
3tvuB37Acetyl-CoA carboxylase/0.444
3w1f1O5Dual specificity protein kinase TTK2.7.12.10.444
4aw3MYVMycinamicin IV hydroxylase/epoxidase/0.444
4c4jX21Dual specificity protein kinase TTK2.7.12.10.444
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.444
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.444
4j55031Gag-Pol polyprotein3.4.23.160.444
4jbtASDCytochrome P450 monooxygenase/0.444
1ckpPVBCyclin-dependent kinase 22.7.11.220.443
1d4iBEGGag-Pol polyprotein3.4.23.160.443
1k6cMK1Gag-Pol polyprotein3.4.23.160.443
1k6pXN3Gag-Pol polyprotein3.4.23.160.443
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.443
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.443
2ivnANPtRNA N6-adenosine threonylcarbamoyltransferase/0.443
2o0uC0MMitogen-activated protein kinase 102.7.11.240.443
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.443
2y00Y01Beta-1 adrenergic receptor/0.443
2yjxYJXHeat shock protein HSP 90-alpha/0.443
2zb3NDPProstaglandin reductase 21.3.1.480.443
3cylVITBasic phospholipase A2 homolog piratoxin-2/0.443
3qaiXNNKetohexokinase/0.443
3t2zFADSulfide-quinone reductase/0.443
3vjoANPEpidermal growth factor receptor2.7.10.10.443
4fv2EK5Mitogen-activated protein kinase 12.7.11.240.443
4hnf16WCasein kinase I isoform delta2.7.11.10.443
4mxaBK7Calmodulin-like domain protein kinase isoenzyme gamma, related/0.443
1ebyBEBGag-Pol polyprotein3.4.23.160.442
1hvrXK2Gag-Pol polyprotein/0.442
1osvCHCBile acid receptor/0.442
1pmn984Mitogen-activated protein kinase 102.7.11.240.442
2b7zMK1Gag-Pol polyprotein/0.442
3cwkREACellular retinoic acid-binding protein 2/0.442
3itzP66Mitogen-activated protein kinase 14/0.442
3kpkFADSulfide-quinone reductase/0.442
3nwq2NCGag-Pol polyprotein3.4.23.160.442
3q44D50M1 family aminopeptidase3.4.110.442
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.442
4g34924Eukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.442
5ap57RODual specificity protein kinase TTK2.7.12.10.442
1bvgDMPGag-Pol polyprotein3.4.23.160.441
1c1dNAIPhenylalanine dehydrogenase/0.441
1pkdUCNCyclin-dependent kinase 22.7.11.220.441
1sh9RITGag-Pol polyprotein3.4.23.160.441
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.441
2bqvA1AProtease/0.441
2g2hP16Tyrosine-protein kinase ABL12.7.10.20.441
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.441
2ykjYKJHeat shock protein HSP 90-alpha/0.441
2znq401Peroxisome proliferator-activated receptor delta/0.441
3ggfGVDSerine/threonine-protein kinase 26/0.441
3inmNDPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.441
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.441
3tqhNDPQuinone oxidoreductase/0.441
4c4f7CEDual specificity protein kinase TTK2.7.12.10.441
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.441
4z24FADPutative GMC-type oxidoreductase R13510.441
5drdATPAurora kinase A2.7.11.10.441
5iu86DZAdenosine receptor A2a/0.441
5jtbZMAAdenosine receptor A2a/0.441
1dw60Q4Gag-Pol polyprotein3.4.23.160.440
1ec0BEDGag-Pol polyprotein3.4.23.160.440
1o6yACPSerine/threonine-protein kinase PknB2.7.11.10.440
2aazCB3Thymidylate synthase2.1.1.450.440
2q61SF1Peroxisome proliferator-activated receptor gamma/0.440
3cs8BRLPeroxisome proliferator-activated receptor gamma/0.440
3q92XNBKetohexokinase/0.440
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4hgt15GCasein kinase I isoform delta2.7.11.10.440
4n6bCOAUncharacterized protein/0.440
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.440
5iubCLRAdenosine receptor A2a/0.440
5k2dZMAAdenosine receptor A2a/0.440