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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3vquO22Dual specificity protein kinase TTK2.7.12.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3vquO22Dual specificity protein kinase TTK2.7.12.11.000
3w1f1O5Dual specificity protein kinase TTK2.7.12.10.643
4c4f7CEDual specificity protein kinase TTK2.7.12.10.545
4c4h7RODual specificity protein kinase TTK2.7.12.10.545
4c4g7RODual specificity protein kinase TTK2.7.12.10.542
2excJNKMitogen-activated protein kinase 102.7.11.240.528
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.528
1xjdSTUProtein kinase C theta type2.7.11.130.526
2b1pAIZMitogen-activated protein kinase 102.7.11.240.524
3ttjJBIMitogen-activated protein kinase 102.7.11.240.521
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.518
3gubGUBDeath-associated protein kinase 12.7.11.10.516
5auwQUEDeath-associated protein kinase 12.7.11.10.515
2p33J07Mitogen-activated protein kinase 102.7.11.240.513
4d0l093Phosphatidylinositol 4-kinase beta2.7.1.670.512
5awmANPStress-activated protein kinase JNK2.7.11.240.512
3l8p0CEAngiopoietin-1 receptor2.7.10.10.511
4c4iX20Dual specificity protein kinase TTK2.7.12.10.510
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.509
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.508
4qmpDKISerine/threonine-protein kinase 242.7.11.10.508
4jqeANPCasein kinase II subunit alpha2.7.11.10.507
2hog710Serine/threonine-protein kinase Chk12.7.11.10.506
4gmy0X5Tyrosine-protein kinase JAK2/0.506
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.504
3rk507ZCyclin-dependent kinase 22.7.11.220.504
4i22IREEpidermal growth factor receptor2.7.10.10.504
3cgfJNFMitogen-activated protein kinase 102.7.11.240.502
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.501
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.501
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.501
4jbqVX6Aurora kinase A2.7.11.10.501
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.499
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.499
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.499
2o2u738Mitogen-activated protein kinase 102.7.11.240.498
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.497
2eufLQQCyclin-dependent kinase 62.7.11.220.496
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.496
2j0j4STFocal adhesion kinase 12.7.10.20.496
2xp2VGHALK tyrosine kinase receptor2.7.10.10.496
1osvCHCBile acid receptor/0.495
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.494
2iw84SPCyclin-dependent kinase 22.7.11.220.492
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.492
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.492
4jboWPHAurora kinase A2.7.11.10.492
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.492
5ap7SVEDual specificity protein kinase TTK2.7.12.10.492
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.491
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.491
3ormAGSSerine/threonine protein kinase/0.491
4hyu1BKMitogen-activated protein kinase 82.7.11.240.491
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.490
3at4CCKCasein kinase II subunit alpha2.7.11.10.490
3r9dX6BCyclin-dependent kinase 22.7.11.220.490
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.490
4bi0Z0WDual specificity protein kinase TTK2.7.12.10.490
4bi1ZO6Dual specificity protein kinase TTK2.7.12.10.490
2h96893Mitogen-activated protein kinase 82.7.11.240.489
5cvhADPCasein kinase II subunit alpha2.7.11.10.489
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.488
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.488
4jbpYPHAurora kinase A2.7.11.10.488
4jia1K3Tyrosine-protein kinase JAK2/0.488
4wsqKSAAP2-associated protein kinase 12.7.11.10.488
1pmn984Mitogen-activated protein kinase 102.7.11.240.487
2bfyH1NAurora kinase B-A2.7.11.10.487
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.487
4g1wG1WMitogen-activated protein kinase 82.7.11.240.487
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.487
5dr9SKEAurora kinase A2.7.11.10.487
2bujSTUSerine/threonine-protein kinase 16/0.486
2iw94SPCyclin-dependent kinase 22.7.11.220.486
3ttiKBIMitogen-activated protein kinase 102.7.11.240.486
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.486
4ftaH5KSerine/threonine-protein kinase Chk12.7.11.10.486
2c475IDCasein kinase I isoform gamma-2/0.485
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.485
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.485
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.485
1ot7CHCBile acid receptor/0.484
3a7hATPSerine/threonine-protein kinase 242.7.11.10.484
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.484
4c4jX21Dual specificity protein kinase TTK2.7.12.10.484
4e730NRMitogen-activated protein kinase 82.7.11.240.484
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.484
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.483
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.483
3w18N13Aurora kinase A2.7.11.10.483
4dgnLU2Casein kinase II subunit alpha2.7.11.10.483
4wboANWRhodopsin kinase/0.483
2c7xNRBCytochrome P450 monooxygenase PikC/0.482
3f46I2C5,10-methenyltetrahydromethanopterin hydrogenase1.12.98.20.482
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.482
5aaaVGHALK tyrosine kinase receptor2.7.10.10.482
1kzjCB3Thymidylate synthase/0.481
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.481
2cig1DGDihydrofolate reductase1.5.1.30.481
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.481
2xikJ60Serine/threonine-protein kinase 252.7.11.10.481
2zdt46CMitogen-activated protein kinase 102.7.11.240.481
3clyACPFibroblast growth factor receptor 2/0.481
4brxKGWFocal adhesion kinase 12.7.10.20.481
4fz60VGTyrosine-protein kinase SYK2.7.10.20.481
4gk2L66Ephrin type-A receptor 32.7.10.10.481
4gk4L90Ephrin type-A receptor 32.7.10.10.481
4yuqKS1Calmodulin-like domain protein kinase/0.481
1di8DTQCyclin-dependent kinase 22.7.11.220.480
1ouk084Mitogen-activated protein kinase 14/0.480
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.480
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.480
3t2zFADSulfide-quinone reductase/0.480
4c57FEFCyclin-G-associated kinase2.7.11.10.480
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.480
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.479
2uzlC94Cyclin-dependent kinase 22.7.11.220.479
3gc9B45Mitogen-activated protein kinase 112.7.11.240.479
3k5uPFQAurora kinase A2.7.11.10.479
3zm422TDual specificity mitogen-activated protein kinase kinase 12.7.12.20.479
5ap57RODual specificity protein kinase TTK2.7.12.10.479
1oguST8Cyclin-dependent kinase 22.7.11.220.478
2etm7PYFocal adhesion kinase 12.7.10.20.478
2q61SF1Peroxisome proliferator-activated receptor gamma/0.478
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.478
1pkdUCNCyclin-dependent kinase 22.7.11.220.477
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.477
2qa2FADPolyketide oxygenase CabE/0.477
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.477
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.477
4anqVGHALK tyrosine kinase receptor2.7.10.10.477
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.477
4hee14RPeroxisome proliferator-activated receptor gamma/0.477
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.477
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.476
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.476
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.476
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.476
2yfxVGHALK tyrosine kinase receptor2.7.10.10.476
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.476
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.476
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.476
4kba1QMCasein kinase I isoform delta2.7.11.10.476
4xgxADPFAD:protein FMN transferase/0.476
5dr6SKEAurora kinase A2.7.11.10.476
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.475
2j0m4STFocal adhesion kinase 12.7.10.20.475
2x6dX6DAurora kinase A2.7.11.10.475
3be9P04Casein kinase II subunit alpha2.7.11.10.475
4c58824Cyclin-G-associated kinase2.7.11.10.475
4dfl0K0Tyrosine-protein kinase SYK2.7.10.20.475
4ez50RSCyclin-dependent kinase 62.7.11.220.475
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.475
1ie4T44Transthyretin/0.474
2gtk208Peroxisome proliferator-activated receptor gamma/0.474
2izsBRQCasein kinase I isoform gamma-32.7.11.10.474
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.474
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.474
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.473
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.473
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.473
3syiFADSulfide-quinone reductase/0.473
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.473
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.473
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.473
5a3bAPRSIR2 family protein/0.473
5uviZMAAdenosine receptor A2a/0.473
1h1s4SPCyclin-dependent kinase 22.7.11.220.472
1tdrMTXDihydrofolate reductase1.5.1.30.472
2pvnP63Casein kinase II subunit alpha2.7.11.10.472
2qo9ANPEphrin type-A receptor 32.7.10.10.472
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.472
3fl8RARDihydrofolate reductase/0.472
3s2pPMUCyclin-dependent kinase 22.7.11.220.472
3sheI85MAP kinase-activated protein kinase 32.7.11.10.472
4cd0AWJALK tyrosine kinase receptor2.7.10.10.472
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.472
4hvh19RTyrosine-protein kinase JAK32.7.10.20.472
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.472
4xldBRLPeroxisome proliferator-activated receptor gamma/0.472
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.471
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.471
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.471
4hvi19STyrosine-protein kinase JAK32.7.10.20.471
4mf129YTyrosine-protein kinase ITK/TSK2.7.10.20.471
4mq22C4Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.471
5dmzADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.471
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.470
2g78REACellular retinoic acid-binding protein 2/0.470
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.470
3cgoJNOMitogen-activated protein kinase 102.7.11.240.470
4erwSTUCyclin-dependent kinase 22.7.11.220.470
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.470
4k2xFADPolyketide oxygenase/hydroxylase/0.470
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.470
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.470
1e9hINRCyclin-dependent kinase 22.7.11.220.469
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.469
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.469
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.469
3r9hZ67Cyclin-dependent kinase 22.7.11.220.469
3t2kFADSulfide-quinone reductase/0.469
4aw3MYVMycinamicin IV hydroxylase/epoxidase/0.469
4foc0UUALK tyrosine kinase receptor2.7.10.10.469
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.469
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.469
1bygSTUTyrosine-protein kinase CSK/0.468
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.468
2xa4AZ5Tyrosine-protein kinase JAK2/0.468
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.468
3rkb12ZCyclin-dependent kinase 22.7.11.220.468
3uvqFS8Mitogen-activated protein kinase 14/0.468
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.468
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.468
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.468
4nka2K7Fibroblast growth factor receptor 1/0.468
4xumIMNPeroxisome proliferator-activated receptor gamma/0.468
5a3cNADSIR2 family protein/0.468
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.467
1yb5NAPQuinone oxidoreductase1.6.5.50.467
2x1nX1NCyclin-dependent kinase 22.7.11.220.467
3axwTIDCasein kinase II subunit alpha2.7.11.10.467
3fln3FNMitogen-activated protein kinase 14/0.467
3inmNDPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.467
3qtqX35Cyclin-dependent kinase 22.7.11.220.467
3t14FADSulfide-quinone reductase/0.467
3zk5Z18Cytochrome P450 monooxygenase PikC/0.467
4ele31IDihydrofolate reductase/0.467
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.467
4fto3HKSerine/threonine-protein kinase Chk12.7.11.10.467
4hfmNAP2-alkenal reductase (NADP(+)-dependent)/0.467
4lopSB4Mitogen-activated protein kinase 14/0.467
2yiqYIQSerine/threonine-protein kinase Chk22.7.11.10.466
2zva1N1Tyrosine-protein kinase Lyn2.7.10.20.466
3h9f92MDual specificity protein kinase TTK2.7.12.10.466
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.466
3sz0FADSulfide-quinone reductase/0.466
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.466
4nb6444Nuclear receptor ROR-gamma/0.466
5k2cZMAAdenosine receptor A2a/0.466
1oiyN41Cyclin-dependent kinase 22.7.11.220.465
2itnANPEpidermal growth factor receptor2.7.10.10.465
2pvyACPFibroblast growth factor receptor 2/0.465
2zjwREFCasein kinase II subunit alpha2.7.11.10.465
3aoxEMHALK tyrosine kinase receptor2.7.10.10.465
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.465
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.465
3oom507Activin receptor type-12.7.11.300.465
3sgx0FWDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.465
3zuxTCHTransporter/0.465
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.465
4dgo0JWCasein kinase II subunit alpha2.7.11.10.465
4grb0XGCasein kinase II subunit alpha2.7.11.10.465
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.465
4l3j5FIRibosomal protein S6 kinase beta-12.7.11.10.465
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.465
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.465
4wkqIREEpidermal growth factor receptor2.7.10.10.465
4ysjADPCalmodulin-like domain protein kinase/0.465
5dt0SKEAurora kinase A2.7.11.10.465
5k2aZMAAdenosine receptor A2a/0.465
1sozVAL_TYR_GLN_PHESerine endoprotease DegS3.4.21.1070.464
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.464
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.464
2w05FRTCyclin-dependent kinase 22.7.11.220.464
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.464
2ylrFADPhenylacetone monooxygenase1.14.13.920.464
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.464
3at3ATKCasein kinase II subunit alpha2.7.11.10.464
3gu6ADPDeath-associated protein kinase 12.7.11.10.464
3gxlQIGTGF-beta receptor type-12.7.11.300.464
3qtwX3ACyclin-dependent kinase 22.7.11.220.464
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.464
4elf35IDihydrofolate reductase/0.464
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.464
4l9kEHFSerum albumin/0.464
4w9wYDJBMP-2-inducible protein kinase2.7.11.10.464
4xey1N1Tyrosine-protein kinase ABL12.7.10.20.464
1menGARTrifunctional purine biosynthetic protein adenosine-32.1.2.20.463
1oiuN76Cyclin-dependent kinase 22.7.11.220.463
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.463
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.463
2pwcG3GGag-Pol polyprotein3.4.23.160.463
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.463
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.463
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.463
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.463
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.463
3fmkFMKMitogen-activated protein kinase 14/0.463
3kpkFADSulfide-quinone reductase/0.463
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.463
4ansVGHALK tyrosine kinase receptor2.7.10.10.463
4c62XWWTyrosine-protein kinase JAK2/0.463
4elb34RDihydrofolate reductase/0.463
4mxyDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.463
4mxzDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.463
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.462
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.462
2prh238Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.462
2qfxNDPIsocitrate dehydrogenase [NADP], mitochondrial1.1.1.420.462
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.462
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.462
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.462
3eljGS7Mitogen-activated protein kinase 82.7.11.240.462
3nx4NAPPutative oxidoreductase/0.462
3qtxX43Cyclin-dependent kinase 22.7.11.220.462
3ztxZTXAurora kinase B-A2.7.11.10.462
4eok4SPCyclin-dependent kinase 22.7.11.220.462
4hnf16WCasein kinase I isoform delta2.7.11.10.462
4nks2M2Fibroblast growth factor receptor 1/0.462
4qmzB49Serine/threonine-protein kinase 242.7.11.10.462
1u4dDBQActivated CDC42 kinase 1/0.461
2dr3ADPUPF0273 protein PH0284/0.461
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.461
2of4979Tyrosine-protein kinase Lck2.7.10.20.461
2vu3LZECyclin-dependent kinase 22.7.11.220.461
2wihP48Cyclin-dependent kinase 22.7.11.220.461
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.461
3fhyATPPyridoxal kinase2.7.1.350.461
3mvl38PMitogen-activated protein kinase 14/0.461
3t1tGDPProbable gliding protein mglA/0.461
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.461
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.461
4b7dQLECytochrome P450 monooxygenase PikC/0.461
4id71G0Activated CDC42 kinase 1/0.461
4j97ACPFibroblast growth factor receptor 2/0.461
4jbiNDPAlcohol dehydrogenase (Zinc)/0.461
4jkt04AGlutaminase kidney isoform, mitochondrial3.5.1.20.461
4y8wSTRSteroid 21-hydroxylase/0.461
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.461
5e8wSTUTGF-beta receptor type-12.7.11.300.461
5e8ySTUTGF-beta receptor type-22.7.11.300.461
1ckpPVBCyclin-dependent kinase 22.7.11.220.460
1e3eNAIAlcohol dehydrogenase 41.1.1.10.460
1iyzNDPProbable quinone oxidoreductase/0.460
1yvj4STTyrosine-protein kinase JAK32.7.10.20.460
1zyjBI5Mitogen-activated protein kinase 14/0.460
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.460
2gjlFMNNitronate monooxygenase1.13.12.160.460
2i4zDRHPeroxisome proliferator-activated receptor gamma/0.460
2izrBRKCasein kinase I isoform gamma-32.7.11.10.460
2o0uC0MMitogen-activated protein kinase 102.7.11.240.460
2w17I19Cyclin-dependent kinase 22.7.11.220.460
2w4iVGAGlutamate racemase/0.460
2xb7GUIALK tyrosine kinase receptor2.7.10.10.460
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.460
3jy0LYGSerine/threonine-protein kinase pim-12.7.11.10.460
3qaiXNNKetohexokinase/0.460
3t8oATPRhodopsin kinase/0.460
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.460
4bcnT9NCyclin-dependent kinase 22.7.11.220.460
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.460
4hgt15GCasein kinase I isoform delta2.7.11.10.460
4mcv29KProto-oncogene tyrosine-protein kinase Src2.7.10.20.460
1om1IQACasein kinase II subunit alpha2.7.11.10.459
1rbyKEUTrifunctional purine biosynthetic protein adenosine-32.1.2.20.459
1uuoBRFDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.459
1wvxBD4Death-associated protein kinase 12.7.11.10.459
2b0m201Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.459
2vgoAD5Aurora kinase B-A2.7.11.10.459
3m6iNADL-arabinitol 4-dehydrogenase1.1.1.120.459
3mdvCL6Cholesterol 24-hydroxylase/0.459
3py0SU9Cyclin-dependent kinase 22.7.11.220.459
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.459
4aotGW8Serine/threonine-protein kinase 102.7.11.10.459
4b99R4LMitogen-activated protein kinase 72.7.11.240.459
4bgg844Activin receptor type-12.7.11.300.459
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.459
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.459
4z34ON7Lysophosphatidic acid receptor 1/0.459
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.458
2qa1FADPgaE/0.458
2uzbC75Cyclin-dependent kinase 22.7.11.220.458
2wotZZGTGF-beta receptor type-12.7.11.300.458
2xnbY8LCyclin-dependent kinase 22.7.11.220.458
2xrwANPMitogen-activated protein kinase 82.7.11.240.458
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.458
3a60STURibosomal protein S6 kinase beta-12.7.11.10.458
3e5aVX6Aurora kinase A2.7.11.10.458
3ix9MTXDihydrofolate reductase1.5.1.30.458
3roc29AMitogen-activated protein kinase 14/0.458
3rukAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.458
3w78CBDFMN-dependent NADH-azoreductase/0.458
4fkr45KCyclin-dependent kinase 22.7.11.220.458
4fob0USALK tyrosine kinase receptor2.7.10.10.458
4ftlH0KSerine/threonine-protein kinase Chk12.7.11.10.458
4fyn0VETyrosine-protein kinase SYK2.7.10.20.458
4i0r1B4Tyrosine-protein kinase SYK2.7.10.20.458
4jayFADUDP-N-acetylenolpyruvoylglucosamine reductase/0.458
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.458
5bvw1N1Epithelial discoidin domain-containing receptor 12.7.10.10.458
5cnoANPEpidermal growth factor receptor2.7.10.10.458
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.457
1ke6LS2Cyclin-dependent kinase 22.7.11.220.457
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.457
2bx8AZQSerum albumin/0.457
2c5nCK8Cyclin-dependent kinase 22.7.11.220.457
2fgiPD1Fibroblast growth factor receptor 1/0.457
2q5g1FAPeroxisome proliferator-activated receptor delta/0.457
3cylVITBasic phospholipase A2 homolog piratoxin-2/0.457
3hp552PMitogen-activated protein kinase 14/0.457
3icrCOACoenzyme A disulfide reductase/0.457
3oroAGSSerine/threonine protein kinase/0.457
3qu0X40Cyclin-dependent kinase 22.7.11.220.457
4fv9E71Mitogen-activated protein kinase 12.7.11.240.457
4jq9FADDihydrolipoyl dehydrogenase/0.457
4klaCHDFerrochelatase, mitochondrial4.99.1.10.457
4twpAXITyrosine-protein kinase ABL12.7.10.20.457
5e8xSTUTGF-beta receptor type-12.7.11.300.457
5upjUINGag-Pol polyprotein/0.457
4z35ON9Lysophosphatidic acid receptor 1/0.457
1gih1PUCyclin-dependent kinase 22.7.11.220.456
1oi9N20Cyclin-dependent kinase 22.7.11.220.456
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.456
2e98B29Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.456
2hw2RFPRifampin ADP-ribosyl transferase/0.456
2igoFADPyranose 2-oxidase/0.456
2zmd537Dual specificity protein kinase TTK2.7.12.10.456
2zv9PP2Tyrosine-protein kinase Lyn2.7.10.20.456
3mtfA3FActivin receptor type-12.7.11.300.456
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.456
3o0g3O0Cyclin-dependent-like kinase 52.7.11.10.456
4acm7YGCyclin-dependent kinase 22.7.11.220.456
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4fkw62KCyclin-dependent kinase 22.7.11.220.456
4fx360KCyclin-dependent kinase 22.7.11.220.456
1i7iAZ2Peroxisome proliferator-activated receptor gamma/0.455
1jnkANPMitogen-activated protein kinase 102.7.11.240.455
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.455
1pxmCK5Cyclin-dependent kinase 22.7.11.220.455
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.455
2bheBRYCyclin-dependent kinase 22.7.11.220.455
2jkoBIJFocal adhesion kinase 12.7.10.20.455
2x9fX9FEphrin type-B receptor 42.7.10.10.455
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.455
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.455
3dogNNNCyclin-dependent kinase 22.7.11.220.455
3i59N6RCRP-like cAMP-activated global transcriptional regulator/0.455
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
3qlrNDPDihydrofolate reductase1.5.1.30.455
3wd7COAAcridone synthase/0.455
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.455
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.455
4kuhCAA3-hydroxybutyryl-CoA dehydrogenase/0.455
4oj4DIFPeroxisome proliferator-activated receptor gamma/0.455
5l8lADPAurora kinase A2.7.11.10.455
1bveDMPGag-Pol polyprotein3.4.23.160.454
1d3hA26Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.454
1pmv537Mitogen-activated protein kinase 102.7.11.240.454
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.454
2e9cB75Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.454
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.454
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.454
2xyuQ9GEphrin type-A receptor 42.7.10.10.454
2znoS44Peroxisome proliferator-activated receptor gamma/0.454
3hwrNDP2-dehydropantoate 2-reductase/0.454
3icsADPCoenzyme A disulfide reductase/0.454
3my5RFZCyclin-dependent kinase 22.7.11.220.454
3poz03PEpidermal growth factor receptor2.7.10.10.454
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
3qzgX67Cyclin-dependent kinase 22.7.11.220.454
3tea4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.454
3tmz06XCytochrome P450 2B41.14.14.10.454
3umxQ18Serine/threonine-protein kinase pim-12.7.11.10.454
3unk0BYCyclin-dependent kinase 22.7.11.220.454
4b8mVX6Aurora kinase B-A2.7.11.10.454
4bdbODOSerine/threonine-protein kinase Chk22.7.11.10.454
4eor4SPCyclin-dependent kinase 22.7.11.220.454
4fuxE75Mitogen-activated protein kinase 12.7.11.240.454
4kbk1QGCasein kinase I isoform delta2.7.11.10.454
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.454
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.454
4xgiNADGlutamate dehydrogenase/0.454
5aacVGHALK tyrosine kinase receptor2.7.10.10.454
1aj8COACitrate synthase/0.453
1cbrREACellular retinoic acid-binding protein 1/0.453
1kkq471Peroxisome proliferator-activated receptor alpha/0.453
1v0pPVBCell division control protein 2 homolog2.7.11.220.453
1wygFADXanthine dehydrogenase/oxidase/0.453
2dwbANPAurora kinase A2.7.11.10.453
2j0k4STFocal adhesion kinase 12.7.10.20.453
2x4f16XMyosin light chain kinase family member 42.7.11.10.453
2xclANPPhosphoribosylamine--glycine ligase/0.453
3bu5ATPInsulin receptor2.7.10.10.453
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.453
3gc8B45Mitogen-activated protein kinase 112.7.11.240.453
3gobHXXDdmC/0.453
3h65I2C5,10-methenyltetrahydromethanopterin hydrogenase1.12.98.20.453
3l08ZIGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.453
4a4vYFDPeroxisome proliferator-activated receptor gamma/0.453
4ez30S0Cyclin-dependent kinase 22.7.11.220.453
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.453
4gub0Y4Casein kinase II subunit alpha2.7.11.10.453
4im2BX7Serine/threonine-protein kinase TBK12.7.11.10.453
4loqSB4Mitogen-activated protein kinase 14/0.453
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.453
4riyADPEpidermal growth factor receptor2.7.10.10.453
5dpvSKEAurora kinase A2.7.11.10.453
5dr2ATPAurora kinase A2.7.11.10.453
1ke7LS3Cyclin-dependent kinase 22.7.11.220.452
1q5kTMUGlycogen synthase kinase-3 beta2.7.11.260.452
2c6o4SPCyclin-dependent kinase 22.7.11.220.452
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.452
2izt23DCasein kinase I isoform gamma-32.7.11.10.452
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.452
2vv9IM9Cyclin-dependent kinase 22.7.11.220.452
2x2lX2LProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.452
2x9dITCTetracycline repressor protein class D/0.452
2xngA0HAurora kinase A2.7.11.10.452
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.452
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.452
3d84NDPDihydrofolate reductase1.5.1.30.452
3fi3JK2Mitogen-activated protein kinase 102.7.11.240.452
3fskRO6Mitogen-activated protein kinase 14/0.452
3ggfGVDSerine/threonine-protein kinase 26/0.452
3i0rRT3Gag-Pol polyprotein2.7.7.490.452
3och2MXDihydrofolate reductase1.5.1.30.452
3qwbNDPProbable quinone oxidoreductase1.6.5.50.452
4bgh3I6Cyclin-dependent kinase 22.7.11.220.452
4dtk7LISerine/threonine-protein kinase pim-12.7.11.10.452
4ft3H1KSerine/threonine-protein kinase Chk12.7.11.10.452
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.452
4lx9ACON-alpha-acetyltransferase2.3.10.452
4ryvZEAProtein LlR18A/0.452
1cc2FADCholesterol oxidase1.1.3.60.451
1jpaANPEphrin type-B receptor 22.7.10.10.451
1lriCLRBeta-elicitin cryptogein/0.451
1mjbACOHistone acetyltransferase ESA1/0.451
2fzmFADBifunctional protein PutA1.5.5.20.451
2itzIREEpidermal growth factor receptor2.7.10.10.451
2ji7OXTOxalyl-CoA decarboxylase4.1.1.80.451
2npaMMBPeroxisome proliferator-activated receptor alpha/0.451
2pwlACPFibroblast growth factor receptor 2/0.451
2q4wFADCytokinin dehydrogenase 71.5.99.120.451
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.451
2xmyCDKCyclin-dependent kinase 22.7.11.220.451
2yaaATPDeath-associated protein kinase 2/0.451
3bv3P39Mitogen-activated protein kinase 14/0.451
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.451
3ctj320Hepatocyte growth factor receptor2.7.10.10.451
3dcv55ESerine/threonine-protein kinase pim-12.7.11.10.451
3dl9V2HVitamin D 25-hydroxylase/0.451
3gu5ANPDeath-associated protein kinase 12.7.11.10.451
3qa2XNAKetohexokinase/0.451
3rmf20ZCyclin-dependent kinase 22.7.11.220.451
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.451
3zlx5EZDual specificity mitogen-activated protein kinase kinase 12.7.12.20.451
3zonIK1Non-receptor tyrosine-protein kinase TYK22.7.10.20.451
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.451
4cnjFADL-amino acid oxidase/0.451
4elg52JDihydrofolate reductase/0.451
4g34924Eukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.451
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.451
4gk3L87Ephrin type-A receptor 32.7.10.10.451
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.451
4r8qADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.451
5k2bZMAAdenosine receptor A2a/0.451
1b16NAQAlcohol dehydrogenase1.1.1.10.450
1ebwBEIGag-Pol polyprotein3.4.23.160.450
1i44ACPInsulin receptor2.7.10.10.450
1i8tFADUDP-galactopyranose mutase5.4.99.90.450
1idb0DOGag-Pol polyprotein/0.450
1k6pXN3Gag-Pol polyprotein3.4.23.160.450
1l2jETCEstrogen receptor beta/0.450
1n4hREANuclear receptor ROR-beta/0.450
1pn3TYDdTDP-epi-vancosaminyltransferase2.4.1.3110.450
1tj1FADBifunctional protein PutA1.5.5.20.450
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.450
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.450
1zys199Serine/threonine-protein kinase Chk12.7.11.10.450
2f2cAP9Cyclin-dependent kinase 62.7.11.220.450
2of2547Tyrosine-protein kinase Lck2.7.10.20.450
2zb3NDPProstaglandin reductase 21.3.1.480.450
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.450
3emg685Tyrosine-protein kinase SYK2.7.10.20.450
3h0aD30Peroxisome proliferator-activated receptor gamma/0.450
3hl7I47Mitogen-activated protein kinase 14/0.450
3m8qDJZGag-Pol polyprotein2.7.7.490.450
3qrwNDPPutative ketoacyl reductase1.3.10.450
3roy22ZCyclin-dependent kinase 22.7.11.220.450
3sgtP09Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)/0.450
3zdu38RCyclin-dependent kinase-like 32.7.11.220.450
4hw319GInduced myeloid leukemia cell differentiation protein Mcl-1/0.450
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.450
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.450
4o0wADNAurora kinase A2.7.11.10.450
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.450
4uuxAPRCinA-like protein/0.450
4wujFMNGlycoside hydrolase family 15, cellulose signaling associated protein envoy/0.450
1adfTADAlcohol dehydrogenase E chain1.1.1.10.449
1c6yMK1Protease/0.449
1pyePM1Cyclin-dependent kinase 22.7.11.220.449
1zeoC01Peroxisome proliferator-activated receptor gamma/0.449
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.449
2h2qNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.449
2j0lANPFocal adhesion kinase 12.7.10.20.449
2np8CC3Aurora kinase A2.7.11.10.449
2py3ACPFibroblast growth factor receptor 2/0.449
2vrx447Aurora kinase B-A2.7.11.10.449
2wqeADPAurora kinase A2.7.11.10.449
2yfeYFEPeroxisome proliferator-activated receptor gamma/0.449
3gggNADPrephenate dehydrogenase/0.449
3icsCOACoenzyme A disulfide reductase/0.449
3jpv1DRSerine/threonine-protein kinase pim-12.7.11.10.449
3p3e3P3UDP-3-O-acyl-N-acetylglucosamine deacetylase/0.449
3r9nZ68Cyclin-dependent kinase 22.7.11.220.449
3rpv26ZCyclin-dependent kinase 22.7.11.220.449
3uli1N3Cyclin-dependent kinase 22.7.11.220.449
3vs1VSATyrosine-protein kinase HCK2.7.10.20.449
3zxtACPDeath-associated protein kinase 12.7.11.10.449
4awiAQ2Mitogen-activated protein kinase 82.7.11.240.449
4bhzZ0BDual specificity protein kinase TTK2.7.12.10.449
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
4fehFADDecaprenylphosphoryl-beta-D-ribose oxidase/0.449
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.449
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.449
4g170VNCasein kinase I isoform gamma-32.7.11.10.449
4jvb1M0Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.449
4nr42LKCREB-binding protein/0.449
4o0uADNAurora kinase A2.7.11.10.449
4xcvNDPProbable hydroxyacid dehydrogenase protein/0.449
4zseANPEpidermal growth factor receptor2.7.10.10.449
5av2KMPDeath-associated protein kinase 12.7.11.10.449
5av3KMPDeath-associated protein kinase 12.7.11.10.449
1oirHDYCyclin-dependent kinase 22.7.11.220.448
1ppm0P1Penicillopepsin-13.4.23.200.448
1z5mLI83-phosphoinositide-dependent protein kinase 12.7.11.10.448
2aibERGBeta-elicitin cinnamomin/0.448
2ardFDAFlavin-dependent tryptophan halogenase PrnA1.14.19.90.448
2bpw1INGag-Pol polyprotein3.4.23.160.448
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.448
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.448
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.448
2cmwOLPCasein kinase I isoform gamma-12.7.11.10.448
2gtmLIDMitogen-activated protein kinase 14/0.448
2ittAEEEpidermal growth factor receptor2.7.10.10.448
2om9AJAPeroxisome proliferator-activated receptor gamma/0.448
2pzpACPFibroblast growth factor receptor 2/0.448
2vx17X8Ephrin type-B receptor 42.7.10.10.448
2vzmNRBCytochrome P450 monooxygenase PikC/0.448
2wmvZYVSerine/threonine-protein kinase Chk12.7.11.10.448
2yylFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.448
2zb0GK3Mitogen-activated protein kinase 14/0.448
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.448
3drcMTXDihydrofolate reductase1.5.1.30.448
3et7349Protein-tyrosine kinase 2-beta2.7.10.20.448
3eteNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.448
3hhu819Heat shock protein HSP 90-alpha/0.448
3kduNKSPeroxisome proliferator-activated receptor alpha/0.448
3qtzX42Cyclin-dependent kinase 22.7.11.220.448
3ral04ZCyclin-dependent kinase 22.7.11.220.448
3t2yFADSulfide-quinone reductase/0.448
3v3vMYUMitogen-activated protein kinase 82.7.11.240.448
3vweCOAAlpha-tubulin N-acetyltransferase 1/0.448
3zewSTUEphrin type-B receptor 42.7.10.10.448
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.448
4ix6ADPUncharacterized protein/0.448
4tleAGSCircadian clock protein kinase KaiC2.7.11.10.448
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.448
5amnDTQProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.448
1drbMTXDihydrofolate reductase1.5.1.30.447
1ke9LS5Cyclin-dependent kinase 22.7.11.220.447
1tduCB3Thymidylate synthase/0.447
1y0s331Peroxisome proliferator-activated receptor delta/0.447
2azzTCHPhospholipase A2, major isoenzyme3.1.1.40.447
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
2hw1ANPKetohexokinase/0.447
2j7t274Serine/threonine-protein kinase 102.7.11.10.447
2pvhP19Casein kinase II subunit alpha2.7.11.10.447
2pz5ACPFibroblast growth factor receptor 2/0.447
2uzoC62Cyclin-dependent kinase 22.7.11.220.447
2xru400Aurora kinase A2.7.11.10.447
3gfbNADL-threonine 3-dehydrogenase/0.447
3kf7L9GMitogen-activated protein kinase 14/0.447
3p6oETGCamphor 5-monooxygenase1.14.15.10.447
3q92XNBKetohexokinase/0.447
3qqkX02Cyclin-dependent kinase 22.7.11.220.447
3vetADPnebramycin 5' synthase6.1.2.20.447
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.447
3wmxNADNAD dependent epimerase/dehydratase/0.447
4a9rRU5Serine/threonine-protein kinase Chk22.7.11.10.447
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.447
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.447
4bfxZVXPantothenate kinase2.7.1.330.447
4btjADPTau-tubulin kinase 12.7.11.10.447
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.447
4jq8KJ8Epidermal growth factor receptor2.7.10.10.447
4kb81QNCasein kinase I isoform delta2.7.11.10.447
4nkvAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.447
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.447
5l7dCLRSmoothened homolog/0.447
1nzdUPGDNA beta-glucosyltransferase/0.446
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.446
1vyzN5BCyclin-dependent kinase 22.7.11.220.446
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.446
2aazCB3Thymidylate synthase2.1.1.450.446
2po7CHDFerrochelatase, mitochondrial4.99.1.10.446
2y98MIVMycinamicin IV hydroxylase/epoxidase/0.446
3a62STURibosomal protein S6 kinase beta-12.7.11.10.446
3bqr4RBDeath-associated protein kinase 3/0.446
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.446
3cbsR12Cellular retinoic acid-binding protein 2/0.446
3flzFLZMitogen-activated protein kinase 14/0.446
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.446
3nga3NGCasein kinase II subunit alpha2.7.11.10.446
3s4qNK0Mitogen-activated protein kinase 14/0.446
3sw719KCyclin-dependent kinase 22.7.11.220.446
3te4ACODopamine N-acetyltransferase/0.446
3u4cNDPNADPH-dependent reductase BacG/0.446
3vrwYS5Vitamin D3 receptor/0.446
3zuyTCHTransporter/0.446
4af3VX6Aurora kinase B2.7.11.10.446
4b8lA0PAurora kinase B-A2.7.11.10.446
4e37NDPCatalase1.11.1.60.446
4elb34SDihydrofolate reductase/0.446
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.446
4qi5FADCellobiose dehydrogenase/0.446
5eypLOCTubulin beta chain/0.446
5itzLOCTubulin beta-2B chain/0.446
1e6eFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.445
1fm9570Peroxisome proliferator-activated receptor gamma/0.445
1fy7COAHistone acetyltransferase ESA1/0.445
1pxpCK8Cyclin-dependent kinase 22.7.11.220.445
1tw2ERTCarminomycin 4-O-methyltransferase DnrK2.1.1.2920.445
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.445
2c6tDT5Cyclin-dependent kinase 22.7.11.220.445
2cbrA80Cellular retinoic acid-binding protein 1/0.445
2henADPEphrin type-B receptor 22.7.10.10.445
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.445
2nuaCOASuccinate--CoA ligase [ADP-forming] subunit alpha6.2.1.50.445
2qd9LGFMitogen-activated protein kinase 14/0.445
2wmrZYRSerine/threonine-protein kinase Chk12.7.11.10.445
2z4bDC8Estrogen receptor beta/0.445
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.445
3f5p741Insulin-like growth factor 1 receptor2.7.10.10.445
3hng8STVascular endothelial growth factor receptor 12.7.10.10.445
3q9xEMOCasein kinase II subunit alpha2.7.11.10.445
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4bddZ0OSerine/threonine-protein kinase Chk22.7.11.10.445
4fsyHK7Serine/threonine-protein kinase Chk12.7.11.10.445
4ftq4HKSerine/threonine-protein kinase Chk12.7.11.10.445
4h3c0YZDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.445
4lggVGGProto-oncogene tyrosine-protein kinase Src2.7.10.20.445
4yryFADGlutamate synthase, beta subunit/0.445
1cbsREACellular retinoic acid-binding protein 2/0.444
1gij2PUCyclin-dependent kinase 22.7.11.220.444
1ia1NDPDihydrofolate reductase1.5.1.30.444
1rf9DBRCamphor 5-monooxygenase1.14.15.10.444
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.444
1vjy460TGF-beta receptor type-12.7.11.300.444
1w06W05Isopenicillin N synthase1.21.3.10.444
2djiFADPyruvate oxidase/0.444
2ehqNAP1-pyrroline-5-carboxylate dehydrogenase/0.444
2fdd385Pol protein/0.444
2g2hP16Tyrosine-protein kinase ABL12.7.10.20.444
2vn0TDZCytochrome P450 2C8/0.444
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.444
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.444
2yn8STUEphrin type-B receptor 42.7.10.10.444
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.444
3efwAK8Aurora kinase A2.7.11.10.444
3hjaNADGlyceraldehyde-3-phosphate dehydrogenase/0.444
3keuATPPyridoxal kinase2.7.1.350.444
3lltANPProtein serine/threonine kinase-1/0.444
3pxkPXKFocal adhesion kinase 12.7.10.20.444
3r8pZ46Cyclin-dependent kinase 22.7.11.220.444
3th8TH9Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.444
3ua506XCytochrome P450 2B61.14.130.444
3unj0BXCyclin-dependent kinase 22.7.11.220.444
3w33W19Epidermal growth factor receptor2.7.10.10.444
4dgmAGICasein kinase II subunit alpha2.7.11.10.444
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.444
4fod0UVALK tyrosine kinase receptor2.7.10.10.444
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4k33ACPFibroblast growth factor receptor 32.7.10.10.444
4kip1R9Mitogen-activated protein kinase 14/0.444
4l8u9AZSerum albumin/0.444
4ly91YYGlucokinase regulatory protein/0.444
4n6z2HWSerine/threonine-protein kinase pim-12.7.11.10.444
4o0mATPCircadian clock protein kinase KaiC2.7.11.10.444
4q73FADBifunctional protein PutA/0.444
4qo9627Serine/threonine-protein kinase 242.7.11.10.444
4y95746Tyrosine-protein kinase/0.444
5auxKMPDeath-associated protein kinase 12.7.11.10.444
1ee0CAA2-pyrone synthase/0.443
1finATPCyclin-dependent kinase 22.7.11.220.443
1k6cMK1Gag-Pol polyprotein3.4.23.160.443
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.443
1ke5LS1Cyclin-dependent kinase 22.7.11.220.443
1nqaNADGlyceraldehyde-3-phosphate dehydrogenase/0.443
1qvnFRIInterleukin-2/0.443
1um0FMNChorismate synthase/0.443
2jkkBI9Focal adhesion kinase 12.7.10.20.443
2q59240Peroxisome proliferator-activated receptor gamma/0.443
2q5p241Peroxisome proliferator-activated receptor gamma/0.443
2vd5BI8Myotonin-protein kinase2.7.11.10.443
2y03Y01Beta-1 adrenergic receptor/0.443
2zybKSLTyrosine-protein kinase Lck2.7.10.20.443
3a7jADPSerine/threonine-protein kinase 242.7.11.10.443
3amyAGICasein kinase II subunit alpha2.7.11.10.443
3e5rNADGlyceraldehyde-3-phosphate dehydrogenase 1, cytosolic1.2.1.120.443
3fkoFKOMitogen-activated protein kinase 14/0.443
3i6oGR6Gag-Pol polyprotein3.4.23.160.443
3jskAHZThiamine thiazole synthase/0.443
3mpaSB2Mitogen-activated protein kinase 14/0.443
3ql8X01Cyclin-dependent kinase 22.7.11.220.443
3qlfPD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.443
3slkNDPPolyketide synthase extender module 2/0.443
3sw418KCyclin-dependent kinase 22.7.11.220.443
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.443
4mbl26LSerine/threonine-protein kinase pim-12.7.11.10.443
4qe6JN3Bile acid receptor/0.443
4tzt468Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.443
1d3gBREDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.442
1hiiC20Gag-Pol polyprotein/0.442
1hvyD16Thymidylate synthase2.1.1.450.442
1oecAA2Fibroblast growth factor receptor 2/0.442
1pxlCK4Cyclin-dependent kinase 22.7.11.220.442
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.442
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.442
2j4z626Aurora kinase A2.7.11.10.442
2nu9COASuccinate--CoA ligase [ADP-forming] subunit alpha6.2.1.50.442
2qo5CHDFatty acid-binding protein 10-A, liver basic/0.442
2r43G3GGag-Pol polyprotein3.4.23.160.442
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.442
2uzeC95Cyclin-dependent kinase 22.7.11.220.442
2vuw5IDSerine/threonine-protein kinase haspin2.7.11.10.442
2wecPP5Penicillopepsin-13.4.23.200.442
2x2mX2MProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.442
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.442
2z3uCRRCytochrome P450/0.442
3em6017Gag-Pol polyprotein3.4.23.160.442
3hx4ANPCalmodulin-domain protein kinase 1/0.442
3i60E86Mitogen-activated protein kinase 12.7.11.240.442
3l0lHC3Nuclear receptor ROR-gamma/0.442
3lctADPALK tyrosine kinase receptor2.7.10.10.442
3ogqAB1Pol polyprotein/0.442
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.442
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.442
4d58BI9Focal adhesion kinase 12.7.10.20.442
4eoi1ROCyclin-dependent kinase 22.7.11.220.442
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4gb20LQGag-Pol polyprotein2.7.7.490.442
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.442
4nxuADPMitochondrial dynamics protein MID51/0.442
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.442
5dt3ATPAurora kinase A2.7.11.10.442
1h1r6CPCyclin-dependent kinase 22.7.11.220.441
1r6g442Thyroid hormone receptor beta/0.441
1tj2FADBifunctional protein PutA1.5.5.20.441
1u54ACPActivated CDC42 kinase 1/0.441
1v0oINRCell division control protein 2 homolog2.7.11.220.441
1wbmBLLPol protein/0.441
2aa0MTPAdenosine kinase2.7.1.200.441
2bpy3INGag-Pol polyprotein3.4.23.160.441
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
2cmjNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.441
2hcdBIVVitamin D3 receptor A/0.441
2pziAXXSerine/threonine-protein kinase PknG2.7.11.10.441
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.441
3cifNADGlyceraldehyde-3-phosphate dehydrogenase/0.441
3eb0DRKUncharacterized protein/0.441
3igoANPCalmodulin-domain protein kinase 1, putative/0.441
3mec65BGag-Pol polyprotein2.7.7.490.441
3mwuBK3Calmodulin-domain protein kinase 1, putative/0.441
3pe6ZYHMonoglyceride lipase/0.441
3rak03ZCyclin-dependent kinase 22.7.11.220.441
3s56ROCProtease/0.441
4c59FEFCyclin-G-associated kinase2.7.11.10.441
4deaNHIAurora kinase A2.7.11.10.441
4dpmCOAMalonyl-CoA reductase1.2.1.750.441
4gxs0YSGlutamate receptor 2/0.441
4h1j0YHProtein-tyrosine kinase 2-beta2.7.10.20.441
4h8nNDPNADPH-dependent conjugated polyketone reductase C2/0.441
4i7fNVEGag-Pol polyprotein2.7.7.490.441
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.441
4jldADPAdenylate kinase/0.441
4jlj1NMDeoxycytidine kinase2.7.1.740.441
4neuQ1AReceptor-interacting serine/threonine-protein kinase 12.7.11.10.441
4o8aFADBifunctional protein PutA1.2.1.880.441
4u2lSFDCholesterol oxidase1.1.3.60.441
4wuoNAD3-isopropylmalate dehydrogenase1.1.1.850.441
4wx1FDAUDP-galactopyranose mutase/0.441
5br4NADLactaldehyde reductase1.1.1.770.441
5dt4ATPAurora kinase A2.7.11.10.441
1ida0POGag-Pol polyprotein3.4.23.470.440
1jlaTNKGag-Pol polyprotein2.7.7.490.440
1nq7ARLNuclear receptor ROR-beta/0.440
1oc1ASVIsopenicillin N synthase1.21.3.10.440
1qaxHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.440
1rbzKT5Trifunctional purine biosynthetic protein adenosine-32.1.2.20.440
1ykdCMPAdenylate cyclase/0.440
2c3qGTXGlutathione S-transferase theta-12.5.1.180.440
2pobGW4Peroxisome proliferator-activated receptor gamma/0.440
2rg5279Mitogen-activated protein kinase 14/0.440
2upjU02Gag-Pol polyprotein3.4.23.160.440
2vx07X7Ephrin type-B receptor 42.7.10.10.440
2wdzNADGalactitol dehydrogenase/0.440
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.440
2y46MIVMycinamicin IV hydroxylase/epoxidase/0.440
2yerTQ1Serine/threonine-protein kinase Chk12.7.11.10.440
2ywwATPAspartate carbamoyltransferase regulatory chain/0.440
2yyiFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.440
3aw9NADNAD-dependent epimerase/dehydratase/0.440
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.440
3dt1P40Mitogen-activated protein kinase 14/0.440
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.440
3gw9VNILanosterol 14-alpha-demethylase/0.440
3h86AP5Adenylate kinase/0.440
3ha7B32Hydroxymycolate synthase MmaA42.1.10.440
3hllI45Mitogen-activated protein kinase 14/0.440
3iok1P6Tyrosine-protein kinase JAK2/0.440
3kvxFMYMitogen-activated protein kinase 102.7.11.240.440
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.440
3mj4FADUDP-galactopyranose mutase/0.440
3oq13OQCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
3qlsNDPDihydrofolate reductase1.5.1.30.440
3rk708ZCyclin-dependent kinase 22.7.11.220.440
3umw596Serine/threonine-protein kinase pim-12.7.11.10.440
4afjSJJGlycogen synthase kinase-3 beta2.7.11.260.440
4b7xNAPProbable oxidoreductase/0.440
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
4nxvGDPMitochondrial dynamics protein MID51/0.440
4wq5ATPtRNA N6-adenosine threonylcarbamoyltransferase/0.440
5cshATPCasein kinase II subunit alpha2.7.11.10.440