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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3vfqAR6Poly [ADP-ribose] polymerase 142.4.2.30

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3vfqAR6Poly [ADP-ribose] polymerase 142.4.2.301.000
3q71AR6Poly [ADP-ribose] polymerase 142.4.2.300.597
4d86ADPPoly [ADP-ribose] polymerase 142.4.2.300.542
5cmsAPRO-acetyl-ADP-ribose deacetylase/0.480
3gw9VNILanosterol 14-alpha-demethylase/0.455
3qwbNDPProbable quinone oxidoreductase1.6.5.50.454
4o1mNADEnoyl-acyl carrier reductase/0.444
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.441