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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3vev0H4Glucokinase2.7.1.2

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3vev0H4Glucokinase2.7.1.21.000
4dhyS41Glucokinase2.7.1.20.621
4ixc1JDGlucokinase2.7.1.20.516
3imxB84Glucokinase2.7.1.20.507
4iwv1J9Glucokinase2.7.1.20.505
3h1vTK1Glucokinase2.7.1.20.495
3id8MRKGlucokinase2.7.1.20.489
3a0iAJIGlucokinase2.7.1.20.473
4mlhVO2Glucokinase2.7.1.20.455
2bu9HFVIsopenicillin N synthase1.21.3.10.445