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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3v8s0HDRho-associated protein kinase 12.7.11.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3v8s0HDRho-associated protein kinase 12.7.11.11.000
4l435FIRibosomal protein S6 kinase beta-12.7.11.10.549
3mvhWFERAC-alpha serine/threonine-protein kinase2.7.11.10.548
1q8wM77cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.543
3cqwCQWRAC-alpha serine/threonine-protein kinase2.7.11.10.543
4l455FIRibosomal protein S6 kinase beta-12.7.11.10.541
4gv10XZRAC-alpha serine/threonine-protein kinase2.7.11.10.538
3dneLL1cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.534
4l445FIRibosomal protein S6 kinase beta-12.7.11.10.531
4uakADPSerine/threonine-protein kinase MRCK beta2.7.11.10.521
2gnfY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.520
1wvxBD4Death-associated protein kinase 12.7.11.10.519
3nynSGVG protein-coupled receptor kinase 62.7.11.160.518
2f2uM77Rho-associated protein kinase 22.7.11.10.517
2etkHFSRho-associated protein kinase 12.7.11.10.511
1g5sI17Cyclin-dependent kinase 22.7.11.220.510
2vo0M03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.507
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.506
3ezvEZVCyclin-dependent kinase 22.7.11.220.505
3mv5XFERAC-alpha serine/threonine-protein kinase2.7.11.10.505
3pxkPXKFocal adhesion kinase 12.7.10.20.503
3zo1SIJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.502
2ijmADPFocal adhesion kinase 12.7.10.20.501
2uw6GVOcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.501
2vo3M04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.501
2pvmP29Casein kinase II subunit alpha2.7.11.10.500
2vnwM01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.500
4ks7X4ZSerine/threonine-protein kinase PAK 62.7.11.10.500
4c35NU3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.499
1finATPCyclin-dependent kinase 22.7.11.220.497
2a5uQYTPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.497
4tnbSGVG protein-coupled receptor kinase 52.7.11.160.497
1snuSTUTyrosine-protein kinase ITK/TSK2.7.10.20.493
3nux3NVCyclin-dependent kinase 62.7.11.220.493
3fz1B98Cyclin-dependent kinase 22.7.11.220.492
4fkt48KCyclin-dependent kinase 22.7.11.220.492
1ykr628Cyclin-dependent kinase 22.7.11.220.491
3tkuM77Serine/threonine-protein kinase MRCK beta2.7.11.10.490
2csnCKICasein kinase I homolog 12.7.11.10.489
1p2a5BNCyclin-dependent kinase 22.7.11.220.486
3tnwF18Cyclin-dependent kinase 22.7.11.220.486
4otiMI1Serine/threonine-protein kinase N1/0.486
5f0a1FBcGMP-dependent protein kinase, putative/0.486
1oecAA2Fibroblast growth factor receptor 2/0.485
2hruADPPhosphoribosylformylglycinamidine synthase subunit PurL/0.483
3emg685Tyrosine-protein kinase SYK2.7.10.20.483
3ml9ML9Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.482
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.480
3jy0LYGSerine/threonine-protein kinase pim-12.7.11.10.480
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.480
1v1k3FPCyclin-dependent kinase 22.7.11.220.479
3gxoMQAMitomycin biosynthesis 6-O-methyltransferase/0.479
3r7uX96Cyclin-dependent kinase 22.7.11.220.479
4f1oACPProbable serine/threonine-protein kinase roco42.7.11.10.479
4nj32KDCyclin-dependent kinase 22.7.11.220.479
2uvzGVJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.478
4fsyHK7Serine/threonine-protein kinase Chk12.7.11.10.478
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.477
4dk50KOPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.477
1fvv107Cyclin-dependent kinase 22.7.11.220.476
3nlv3XANitric oxide synthase, brain1.14.13.390.476
4hvh19RTyrosine-protein kinase JAK32.7.10.20.476
4iazADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.476
4o0sADNAurora kinase A2.7.11.10.476
2b0qADPAminoglycoside 3'-phosphotransferase2.7.1.950.475
2cchATPCyclin-dependent kinase 22.7.11.220.475
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.475
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.474
2a0cCK9Cyclin-dependent kinase 22.7.11.220.474
2gnlH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.474
3dqrJI2Nitric oxide synthase, brain1.14.13.390.474
3qrsNK8Gag-Pol polyprotein3.4.23.160.474
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.474
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.473
3s4qNK0Mitogen-activated protein kinase 14/0.473
3v5w8PRBeta-adrenergic receptor kinase 12.7.11.150.473
4hni16WCasein kinase I isoform epsilon2.7.11.10.473
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.472
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.472
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.472
4fw05KJNitric oxide synthase, brain1.14.13.390.472
2ckeIQUDeath-associated protein kinase 2/0.471
2olcADPMethylthioribose kinase2.7.1.1000.471
3isjA8DPantothenate synthetase6.3.2.10.471
1aq1STUCyclin-dependent kinase 22.7.11.220.470
1y91CT9Cyclin-dependent kinase 22.7.11.220.470
4f640S8Fibroblast growth factor receptor 1/0.470
4ivd15TTyrosine-protein kinase JAK1/0.470
1gthFADDihydropyrimidine dehydrogenase [NADP(+)]1.3.1.20.469
1i9c5ADGlutamate mutase epsilon subunit/0.469
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.469
1rc4DDFDihydrofolate reductase1.5.1.30.469
2r3jSCJCyclin-dependent kinase 22.7.11.220.469
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.469
4eor4SPCyclin-dependent kinase 22.7.11.220.469
4q1y017Gag-Pol polyprotein3.4.23.160.469
5aut2ANDeath-associated protein kinase 12.7.11.10.469
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.468
3gu4ANPDeath-associated protein kinase 12.7.11.10.468
4dtaADNAPH(2'')-Id/0.468
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.467
2gnhH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.467
2pwlACPFibroblast growth factor receptor 2/0.467
4fvz4KJNitric oxide synthase, brain1.14.13.390.467
4gvjADPNon-receptor tyrosine-protein kinase TYK22.7.10.20.467
4jshQ15Nitric oxide synthase, brain1.14.13.390.467
4o0wADNAurora kinase A2.7.11.10.467
1j1bANPGlycogen synthase kinase-3 beta2.7.11.260.466
1p6jDP9Nitric oxide synthase, brain1.14.13.390.466
1pxpCK8Cyclin-dependent kinase 22.7.11.220.466
2i40BLZCyclin-dependent kinase 22.7.11.220.466
2vn9GVDCalcium/calmodulin-dependent protein kinase type II subunit delta2.7.11.170.466
3hztJ60Calmodulin-like domain protein kinase isoform 3/0.466
3r7iX9ICyclin-dependent kinase 22.7.11.220.466
3swrSFGDNA (cytosine-5)-methyltransferase 12.1.1.370.466
1c6zROCProtease/0.465
2z02ATPPhosphoribosylaminoimidazole-succinocarboxamide synthase6.3.2.60.465
3qpjN4IGag-Pol polyprotein3.4.23.160.465
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.464
3qbfJHGGag-Pol polyprotein3.4.23.160.464
4c36ZO9cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.464
5av2KMPDeath-associated protein kinase 12.7.11.10.464
3fzpAGSProtein-tyrosine kinase 2-beta2.7.10.20.463
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.463
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.463
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.463
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.463
4l3j5FIRibosomal protein S6 kinase beta-12.7.11.10.463
1e8wQUEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.462
3n61XFJNitric oxide synthase, brain1.14.13.390.462
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.462
4fx9FADCoenzyme A disulfide reductase1.8.1.140.462
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.462
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.462
3qw2NADMyo-inositol-1-phosphate synthase (Ino1)/0.461
4bgh3I6Cyclin-dependent kinase 22.7.11.220.461
4erwSTUCyclin-dependent kinase 22.7.11.220.461
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.460
3r7yZ04Cyclin-dependent kinase 22.7.11.220.460
4ic7ANPMitogen-activated protein kinase 72.7.11.240.460
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.459
2cd8PXICytochrome P450 monooxygenase PikC/0.459
2chlDKICasein kinase I isoform gamma-32.7.11.10.459
2j0lANPFocal adhesion kinase 12.7.10.20.459
2uw5GVNcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
3lq5SLQCyclin-dependent kinase 92.7.11.220.459
3ow3SMYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
4b8lA0PAurora kinase B-A2.7.11.10.459
4dc32FAPutative adenosine kinase/0.459
4gh30EVQueuine tRNA-ribosyltransferase2.4.2.290.459
4j5j478Gag-Pol polyprotein3.4.23.160.459
4ugaQ05Nitric oxide synthase oxygenase1.14.13.1650.459
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
2r3p3SCCyclin-dependent kinase 22.7.11.220.458
2ydkYDKSerine/threonine-protein kinase Chk12.7.11.10.458
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.458
3wi6YRZMAP kinase-activated protein kinase 22.7.11.10.458
4becATPType I restriction enzyme EcoR124II R protein3.1.21.30.458
4qoeFADRibosyldihydronicotinamide dehydrogenase [quinone]/0.458
1sz3GNPMutT/nudix family protein/0.457
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
3bhy7CPDeath-associated protein kinase 3/0.457
3dcv55ESerine/threonine-protein kinase pim-12.7.11.10.457
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.457
3hv6R39Mitogen-activated protein kinase 14/0.457
4iakADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
4iayADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.457
4lwaQ13Nitric oxide synthase oxygenase1.14.13.1650.457
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.457
4ej4EJ4Delta-type opioid receptor/0.457
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.456
2b53D23Cyclin-dependent kinase 22.7.11.220.456
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
2o2143BApoptosis regulator Bcl-2/0.456
2o98FSC14-3-3-like protein C/0.456
2v8pADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.456
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
2vthLZ2Cyclin-dependent kinase 22.7.11.220.456
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.456
3fpfMTAUncharacterized protein/0.456
3hv71AUMitogen-activated protein kinase 14/0.456
3oqkS52Renin3.4.23.150.456
4bcmT7ZCyclin-dependent kinase 22.7.11.220.456
4j95ACPFibroblast growth factor receptor 2/0.456
4ktc1X3Genome polyprotein3.4.21.980.456
4n6hEJ4Delta-type opioid receptor/0.456
4ndnSAMS-adenosylmethionine synthase isoform type-22.5.1.60.456
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
2hx44HXNitric oxide synthase, brain1.14.13.390.455
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
3nlrJRSNitric oxide synthase, brain1.14.13.390.455
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.455
3nwxKVSGag-Pol polyprotein3.4.23.160.455
3zokNAD3-dehydroquinate synthase, chloroplastic4.2.3.40.455
4jik1KOSerine/threonine-protein kinase Chk12.7.11.10.455
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.455
4req5ADMethylmalonyl-CoA mutase large subunit5.4.99.20.455
4y93746Tyrosine-protein kinase/0.455
5auvAGIDeath-associated protein kinase 12.7.11.10.455
1tqpATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.454
2gfsPQBMitogen-activated protein kinase 14/0.454
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.454
2px5SAHGenome polyprotein2.7.7.480.454
2uw4L15cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
3n0tOPYDipeptidyl peptidase 23.4.14.20.454
3vf7031Gag-Pol polyprotein3.4.23.160.454
4fad0TBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
4lyn1YGCyclin-dependent kinase 22.7.11.220.454
1atnATPActin, alpha skeletal muscle/0.453
2yaaATPDeath-associated protein kinase 2/0.453
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.453
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.453
3nlw3XFNitric oxide synthase, brain1.14.13.390.453
3nnz59WNitric oxide synthase, brain1.14.13.390.453
3nwq2NCGag-Pol polyprotein3.4.23.160.453
3qu0X40Cyclin-dependent kinase 22.7.11.220.453
4fks46KCyclin-dependent kinase 22.7.11.220.453
4h03LARActin, alpha skeletal muscle/0.453
1xjdSTUProtein kinase C theta type2.7.11.130.452
2a1eIPFGag-Pol polyprotein3.4.23.160.452
2iiqC5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.452
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.452
2pvlP55Casein kinase II subunit alpha2.7.11.10.452
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.452
3bheBZNGag-Pol polyprotein3.4.23.160.452
3dawATPActin, alpha skeletal muscle/0.452
3fwrADPTranscriptional repressor CcpN/0.452
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.452
3umw596Serine/threonine-protein kinase pim-12.7.11.10.452
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.452
3vv8B02Beta-secretase 13.4.23.460.452
4f0fACPProbable serine/threonine-protein kinase roco42.7.11.10.452
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.452
4h0yLARActin, alpha skeletal muscle/0.452
4ug5XFKNitric oxide synthase oxygenase1.14.13.1650.452
5dr6SKEAurora kinase A2.7.11.10.452
1m9k7NINitric oxide synthase, endothelial1.14.13.390.451
1pxlCK4Cyclin-dependent kinase 22.7.11.220.451
1pxmCK5Cyclin-dependent kinase 22.7.11.220.451
1q3dSTUGlycogen synthase kinase-3 beta2.7.11.260.451
1wxyFRKAdenosine deaminase3.5.4.40.451
2bpz3INGag-Pol polyprotein3.4.23.160.451
2gqrADPPhosphoribosylaminoimidazole-succinocarboxamide synthase6.3.2.60.451
2r3lSCWCyclin-dependent kinase 22.7.11.220.451
3ekt017Gag-Pol polyprotein3.4.23.160.451
3p79P79Mitogen-activated protein kinase 14/0.451
3pxyJWSCyclin-dependent kinase 22.7.11.220.451
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.451
3zh8C58Protein kinase C iota type2.7.11.130.451
4bebATPType I restriction enzyme EcoR124II R protein3.1.21.30.451
4brxKGWFocal adhesion kinase 12.7.10.20.451
4gy2LARActin, alpha skeletal muscle/0.451
4jsjQJ7Nitric oxide synthase, brain1.14.13.390.451
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.451
4lv7ADPInositol-pentakisphosphate 2-kinase2.7.1.1580.451
4o761M3Bromodomain-containing protein 4/0.451
5dpvSKEAurora kinase A2.7.11.10.451
3oe9ITDC-X-C chemokine receptor type 4/0.451
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
1yvj4STTyrosine-protein kinase JAK32.7.10.20.450
1zzuDP1Nitric oxide synthase, brain1.14.13.390.450
2x1nX1NCyclin-dependent kinase 22.7.11.220.450
3dfcANPDeath-associated protein kinase 12.7.11.10.450
3dndLL2cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
3gu7ADPDeath-associated protein kinase 12.7.11.10.450
3krwBA1Beta-adrenergic receptor kinase 12.7.11.150.450
3lzu017Gag-Pol polyprotein3.4.23.160.450
4ek816KCyclin-dependent kinase 22.7.11.220.450
4fk60UJTyrosine-protein kinase JAK1/0.450
4gu94GUFocal adhesion kinase 12.7.10.20.450
4hnc0UTMandelate racemase/0.450
4hvg19QTyrosine-protein kinase JAK32.7.10.20.450
4im2BX7Serine/threonine-protein kinase TBK12.7.11.10.450
4jhz1KVBeta-glucuronidase3.2.1.310.450
4jrnANPRhoptry kinase family protein/0.450
4k5d1Q6Nitric oxide synthase, brain1.14.13.390.450
4o71CPBBromodomain-containing protein 4/0.450
4y95746Tyrosine-protein kinase/0.450
3qakUKAAdenosine receptor A2a/0.450
1jklANPDeath-associated protein kinase 12.7.11.10.449
1u33LM2Pancreatic alpha-amylase/0.449
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.449
1xl2189Gag-Pol polyprotein3.4.23.160.449
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.449
1zzrDP9Nitric oxide synthase, brain1.14.13.390.449
2pulACPMethylthioribose kinase2.7.1.1000.449
2qnqQN3Gag-Pol polyprotein3.4.23.160.449
3ac5KZMTyrosine-protein kinase Lck2.7.10.20.449
3psyRB9Endothiapepsin3.4.23.220.449
3r8lZ30Cyclin-dependent kinase 22.7.11.220.449
3t54ATPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2/0.449
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4fkr45KCyclin-dependent kinase 22.7.11.220.449
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.449
4mk029XBeta-adrenergic receptor kinase 12.7.11.150.449
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.449
1pxoCK7Cyclin-dependent kinase 22.7.11.220.448
2etrY27Rho-associated protein kinase 12.7.11.10.448
2f3kRO1Protease/0.448
2itqITQEpidermal growth factor receptor2.7.10.10.448
2xmyCDKCyclin-dependent kinase 22.7.11.220.448
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
3buzLARActin, alpha skeletal muscle/0.448
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.448
3lfqA28Cyclin-dependent kinase 22.7.11.220.448
4f1sF1SPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.448
4gu610NFocal adhesion kinase 12.7.10.20.448
1h48C5P2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase4.6.1.120.447
1hvhQ82Gag-Pol polyprotein3.4.23.160.447
1ppkIVVPenicillopepsin-13.4.23.200.447
1q99ANPSerine/threonine-protein kinase SKY12.7.11.10.447
1zzqDP9Nitric oxide synthase, brain1.14.13.390.447
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.447
2vtqLZACyclin-dependent kinase 22.7.11.220.447
2ywvADPPhosphoribosylaminoimidazole-succinocarboxamide synthase/0.447
3eb0DRKUncharacterized protein/0.447
3jx2JI4Nitric oxide synthase, brain1.14.13.390.447
3le62BZCyclin-dependent kinase 22.7.11.220.447
4avgSL6Polymerase acidic protein/0.447
4gqe6KJNitric oxide synthase, brain1.14.13.390.447
4nka2K7Fibroblast growth factor receptor 1/0.447
1w84L12Mitogen-activated protein kinase 14/0.446
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
2b7zMK1Gag-Pol polyprotein/0.446
2duv371Cyclin-dependent kinase 22.7.11.220.446
2vrx447Aurora kinase B-A2.7.11.10.446
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.446
3a62STURibosomal protein S6 kinase beta-12.7.11.10.446
3jx4J11Nitric oxide synthase, brain1.14.13.390.446
3qp0NI8Gag-Pol polyprotein3.4.23.160.446
4anqVGHALK tyrosine kinase receptor2.7.10.10.446
4dymIYZActivin receptor type-12.7.11.300.446
4kttSAMS-adenosylmethionine synthase isoform type-22.5.1.60.446
4rwtANPActin-5C/0.446
4wbbADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
4yryFADGlutamate synthase, beta subunit/0.446
5auxKMPDeath-associated protein kinase 12.7.11.10.446
5cgv0N8Polymerase acidic protein/0.446
1bi9NADRetinal dehydrogenase 2/0.445
1hv9UD1Bifunctional protein GlmU/0.445
1rx4DDFDihydrofolate reductase1.5.1.30.445
1rx7FOLDihydrofolate reductase1.5.1.30.445
2uzoC62Cyclin-dependent kinase 22.7.11.220.445
3gueUPGUTP-glucose-1-phosphate uridylyltransferase 2, putative/0.445
3lfnA27Cyclin-dependent kinase 22.7.11.220.445
3nmhPYVAbscisic acid receptor PYL2/0.445
3p5kP5KMitogen-activated protein kinase 14/0.445
3pe2E1BCasein kinase II subunit alpha2.7.11.10.445
3qyw6PBMitogen-activated protein kinase 12.7.11.240.445
3uvr06FMitogen-activated protein kinase 14/0.445
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.445
4dtk7LISerine/threonine-protein kinase pim-12.7.11.10.445
4ek610KCyclin-dependent kinase 22.7.11.220.445
4ekl0RFRAC-alpha serine/threonine-protein kinase2.7.11.10.445
4gub0Y4Casein kinase II subunit alpha2.7.11.10.445
4j99ACPFibroblast growth factor receptor 2/0.445
4jseQJ2Nitric oxide synthase, brain1.14.13.390.445
4nyeADPPhosphoribosylaminoimidazole-succinocarboxamide synthase6.3.2.60.445
4pl8ATPActin, alpha skeletal muscle/0.445
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.445
4wb9NAIRetinal dehydrogenase 11.2.1.360.445
4y9qC2EUncharacterized protein/0.445
5ero210Fusicoccadiene synthase2.5.1.290.445
5ks72BACarnitine transport ATP-binding protein OpuCA3.6.3.320.445
4djhJDCKappa-type opioid receptor/0.445
1rejB1LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
1svmATPLarge T antigen3.6.40.444
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
2w1hL0FCyclin-dependent kinase 22.7.11.220.444
2yfxVGHALK tyrosine kinase receptor2.7.10.10.444
2yisYISMitogen-activated protein kinase 14/0.444
2yy8MTAtRNA (cytidine(56)-2'-O)-methyltransferase/0.444
3c4zADPRhodopsin kinase/0.444
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.444
3e6oA55Nitric oxide synthase, inducible1.14.13.390.444
3g7jGTXGlutathione transferase GST1-4/0.444
3nny59RNitric oxide synthase, brain1.14.13.390.444
3qqfX07Cyclin-dependent kinase 22.7.11.220.444
3rk708ZCyclin-dependent kinase 22.7.11.220.444
3s56ROCProtease/0.444
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.444
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.444
4bz7B3NHistone deacetylase/0.444
4dggI76Proto-oncogene tyrosine-protein kinase Src2.7.10.20.444
4eomATPCyclin-dependent kinase 22.7.11.220.444
4ib4ERM5-hydroxytryptamine receptor 2B/0.444
4ii5ADPCyclin-dependent kinase 22.7.11.220.444
1bxqPP8Penicillopepsin-13.4.23.200.443
1phhFADp-hydroxybenzoate hydroxylase/0.443
1pvdTPPPyruvate decarboxylase isozyme 1/0.443
1sh9RITGag-Pol polyprotein3.4.23.160.443
1wvySTUDeath-associated protein kinase 12.7.11.10.443
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.443
2qkrIXMCdc2-like CDK2/CDC28 like protein kinase/0.443
2v5aLZLBiotin carboxylase6.3.4.140.443
2vv9IM9Cyclin-dependent kinase 22.7.11.220.443
3iok1P6Tyrosine-protein kinase JAK2/0.443
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.443
3p7aP7AMitogen-activated protein kinase 14/0.443
3qdzPRO_ALA_PRO_ARGProthrombin3.4.21.50.443
3rpy27ZCyclin-dependent kinase 22.7.11.220.443
3t113T1Gag-Pol polyprotein3.4.23.160.443
3t6iNC9Endothiapepsin3.4.23.220.443
3uq6ADNPutative adenosine kinase/0.443
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4ivb1J5Tyrosine-protein kinase JAK1/0.443
4qmuSKESerine/threonine-protein kinase 242.7.11.10.443
5av4GENDeath-associated protein kinase 12.7.11.10.443
1mbzIOTCarboxyethyl-arginine beta-lactam-synthase6.3.3.40.442
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.442
2parTMP5'-deoxynucleotidase YfbR/0.442
2pvnP63Casein kinase II subunit alpha2.7.11.10.442
2xiq5ADMethylmalonyl-CoA mutase, mitochondrial/0.442
3b5iSAHIndole-3-acetate O-methyltransferase 1/0.442
3js2VM1Fibroblast growth factor receptor 1/0.442
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.442
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.442
3vs0VS0Tyrosine-protein kinase HCK2.7.10.20.442
3zpuM8BGag-Pol polyprotein3.4.23.160.442
4fklCK2Cyclin-dependent kinase 22.7.11.220.442
4g3qUD1Bifunctional protein GlmU/0.442
4nk92K5Fibroblast growth factor receptor 1/0.442
4oa5SAHO-methyltransferase family protein/0.442
5dstSAHProtein arginine N-methyltransferase 82.1.10.442
1bxsNADRetinal dehydrogenase 11.2.1.360.441
1dg5TOPDihydrofolate reductase1.5.1.30.441
1ltzHBIPhenylalanine-4-hydroxylase1.14.16.10.441
1z1rHBHGag-Pol polyprotein3.4.23.160.441
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.441
2btsU32Cyclin-dependent kinase 22.7.11.220.441
3nhpHGZRibosyldihydronicotinamide dehydrogenase [quinone]/0.441
3qx4X4BCyclin-dependent kinase 22.7.11.220.441
3r1yX76Cyclin-dependent kinase 22.7.11.220.441
3sai9DRDihydrofolate reductase/0.441
3zo4QWIcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.441
4aqc88ATyrosine-protein kinase JAK2/0.441
4awgCI3Polymerase acidic protein/0.441
4djoMK5Pol polyprotein/0.441
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4imw1EVNitric oxide synthase, brain1.14.13.390.441
4l2oNADAldehyde dehydrogenase, dimeric NADP-preferring/0.441
4pxlNADAldehyde dehydrogenase3/0.441
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.441
5dr9SKEAurora kinase A2.7.11.10.441
5htxADPPutative xylulose kinase/0.441
1k6tXN1Gag-Pol polyprotein3.4.23.160.440
1lcbTMPThymidylate synthase/0.440
1n07FMNRiboflavin kinase2.7.1.260.440
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.440
2c6lDT4Cyclin-dependent kinase 22.7.11.220.440
2c6tDT5Cyclin-dependent kinase 22.7.11.220.440
2f8g017Gag-Pol polyprotein3.4.23.160.440
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.440
2pwcG3GGag-Pol polyprotein3.4.23.160.440
2pwrG4GGag-Pol polyprotein3.4.23.160.440
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.440
3mvjXFEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
3qvsNADMyo-inositol-1-phosphate synthase (Ino1)/0.440
3rkb12ZCyclin-dependent kinase 22.7.11.220.440
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.440
3tm0ANPAminoglycoside 3'-phosphotransferase2.7.1.950.440
3ufqHW5Nitric oxide synthase, brain1.14.13.390.440
3uq9TBNPutative adenosine kinase/0.440
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.440
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.440
4nbuCAA3-oxoacyl-(Acyl-carrier-protein) reductase/0.440
4qofFMNRibosyldihydronicotinamide dehydrogenase [quinone]/0.440
4ug71EVNitric oxide synthase oxygenase1.14.13.1650.440
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.440