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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3v2bAR6Poly [ADP-ribose] polymerase 152.4.2.30

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3v2bAR6Poly [ADP-ribose] polymerase 152.4.2.301.000
5cb3APRO-acetyl-ADP-ribose deacetylase/0.510
3q71AR6Poly [ADP-ribose] polymerase 142.4.2.300.500
3vfqAR6Poly [ADP-ribose] polymerase 142.4.2.300.480
2bfqAR6[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.475
4d86ADPPoly [ADP-ribose] polymerase 142.4.2.300.474
5fsxADPUncharacterized protein/0.474
1v4sMRKGlucokinase2.7.1.20.456
3iidAPRCore histone macro-H2A.1/0.456
2bpoNAPNADPH--cytochrome P450 reductase/0.447
4ambDUDPutative glycosyl transferase/0.447
5cmsAPRO-acetyl-ADP-ribose deacetylase/0.447
1qorNDPQuinone oxidoreductase 1/0.441
3lsmSFDPyranose 2-oxidase/0.441
1rx0FADIsobutyryl-CoA dehydrogenase, mitochondrial1.3.990.440