scPDB - Distribution of Binding site Similarity values of 3v01 entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3v01	3V0	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
3v01	3V0	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	1.000
1s9j	BBM	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.646
2p55	MRA	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.607
3v04	V04	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.604
3pp1	IZG	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.560
4an3	5Y0	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.558
3dy7	1CX	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.557
3os3	3OS	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.557
3vvh	4BM	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.542
3orn	3OR	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.532
4an9	2P7	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.532
4lmn	EUI	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.523
3dv3	MEK	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.511
3e8n	VRA	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.508
4anb	YQY	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.503
4an2	EUI	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.477
3sls	77D	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.469
3zkp	ERB	Erythromycin C-12 hydroxylase	1.14.13.154	0.461
2pk6	O33	V-1 protease	/	0.448
2idw	017	Protease	/	0.443
3lin	E13	Protease	/	0.443