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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3uzxAOM3-oxo-5-beta-steroid 4-dehydrogenase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3uzxAOM3-oxo-5-beta-steroid 4-dehydrogenase/1.000
3uzzTES3-oxo-5-beta-steroid 4-dehydrogenase/0.718
3uzxAOX3-oxo-5-beta-steroid 4-dehydrogenase/0.667
3cotSTR3-oxo-5-beta-steroid 4-dehydrogenase/0.645
3uzzASD3-oxo-5-beta-steroid 4-dehydrogenase/0.638
3cavCI23-oxo-5-beta-steroid 4-dehydrogenase/0.616
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.606
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.591
2gyuHI6Acetylcholinesterase3.1.1.70.524
2j3qTFLAcetylcholinesterase3.1.1.70.522
2xi4AFTAcetylcholinesterase3.1.1.70.522
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.518
2jf0HBPAcetylcholinesterase3.1.1.70.515
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.512
1lkeDOGBilin-binding protein/0.510
1qtiGNTAcetylcholinesterase3.1.1.70.510
1zgbA1EAcetylcholinesterase3.1.1.70.508
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.507
4m0f1YKAcetylcholinesterase3.1.1.70.506
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.505
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.504
4b7zQ4QAcetylcholinesterase3.1.1.70.503
4psbGA3Cytokinin-specific binding protein/0.502
3q7fED2Uncharacterized protein/0.498
5dsg0HKMuscarinic acetylcholine receptor M4/0.498
2j9fTHV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.497
2j9fTHV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial1.2.4.40.497
1h22E10Acetylcholinesterase3.1.1.70.495
1v08NTZ4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic3.2.1.1820.494
3nytULPUDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.494
1dx6GNTAcetylcholinesterase3.1.1.70.493
1p0pBCHCholinesterase3.1.1.80.493
1r5hAO2Methionine aminopeptidase 2/0.493
3v0p4GWHisto-blood group ABO system transferase/0.493
1q23FUAChloramphenicol acetyltransferase2.3.1.280.492
2aot2PMHistamine N-methyltransferase2.1.1.80.492
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.492
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.492
1obnASVIsopenicillin N synthase1.21.3.10.491
1w4lGL8Acetylcholinesterase3.1.1.70.491
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.491
1kw8BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.490
2ea2F77Methionine aminopeptidase 2/0.490
2xupTZ5Acetylcholinesterase3.1.1.70.490
3ihgVAKAklavinone 12-hydroxylase RdmE/0.490
3k8q22APurine nucleoside phosphorylase2.4.2.10.490
3u57DH8Raucaffricine-O-beta-D-glucosidase3.2.1.1250.490
3zc3FADFerredoxin--NADP reductase1.18.1.20.490
1odcA8BAcetylcholinesterase3.1.1.70.489
2ha6SCKAcetylcholinesterase3.1.1.70.489
5d6lCAUBeta-2 adrenergic receptor/0.488
2xufTZ4Acetylcholinesterase3.1.1.70.487
3qeoLLTDeoxycytidine kinase2.7.1.740.487
5fd8A5APutative carboxypeptidase yocD/0.487
1c7oPPGHemolysin/0.486
5c1gGDUHisto-blood group ABO system transferase/0.485
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.484
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.484
3sfy3FYUncharacterized protein/0.484
1ld7U66Protein farnesyltransferase subunit beta2.5.1.580.483
2xuhTZ4Acetylcholinesterase3.1.1.70.483
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.483
3pqbVGPPutative oxidoreductase/0.483
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.483
3uonQNBMuscarinic acetylcholine receptor M2/0.483
2r8oT5XTransketolase 1/0.482
2w6cBM4Acetylcholinesterase3.1.1.70.482
2zevB71Geranylgeranyl pyrophosphate synthase/0.482
1kyvRBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.481
2ct8MSPMethionine--tRNA ligase6.1.1.100.481
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.481
4arbC57Acetylcholinesterase3.1.1.70.481
4c5oFADPutative monooxygenase/0.481
1w6jR71Lanosterol synthase5.4.99.70.480
2rqfJH3Hemolymph juvenile hormone binding protein/0.480
1ld8U49Protein farnesyltransferase subunit beta2.5.1.580.479
1lnmDTXBilin-binding protein/0.479
2cekN8TAcetylcholinesterase3.1.1.70.479
2vbpVB1Isopenicillin N synthase1.21.3.10.479
3c1oNAPEugenol synthase/0.479
2gmsP0PPutative pyridoxamine 5-phosphate-dependent dehydrase/0.478
2gywOBIAcetylcholinesterase3.1.1.70.478
3b8xG4MPutative pyridoxamine 5-phosphate-dependent dehydrase/0.478
4mm729JNa(+):neurotransmitter symporter (Snf family)/0.478
4u140HKMuscarinic acetylcholine receptor M3/0.478
1eveE20Acetylcholinesterase3.1.1.70.477
2ea4F79Methionine aminopeptidase 2/0.477
4bj9UHBTankyrase-22.4.2.300.477
4drhRAPSerine/threonine-protein kinase mTOR2.7.11.10.477
4drhRAPPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.477
4x7uZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.477
2ckmAA7Acetylcholinesterase3.1.1.70.476
2gmuPDGPutative pyridoxamine 5-phosphate-dependent dehydrase/0.476
2ipiAKYAclacinomycin-N/aclacinomycin-A oxidase/0.476
4zu44TGWxcM-like protein/0.476
1t7o152Carnitine O-acetyltransferase2.3.1.70.475
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.475
3pkeY10Methionine aminopeptidase 2/0.475
1fapRAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.474
1fapRAPSerine/threonine-protein kinase mTOR2.7.11.10.474
1qiqACCIsopenicillin N synthase1.21.3.10.474
4jq4IMNAldo-keto reductase family 1 member C2/0.474
1q83TZ5Acetylcholinesterase3.1.1.70.473
2pbzATPUncharacterized protein/0.473
2vteIK4UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.473
2xuoTZ4Acetylcholinesterase3.1.1.70.473
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.473
4jtqFLPAldo-keto reductase family 1 member C2/0.473
1kw9BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.472
1r5gAO1Methionine aminopeptidase 2/0.472
1s63778Protein farnesyltransferase subunit beta2.5.1.580.472
1u65CP0Acetylcholinesterase3.1.1.70.472
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.472
4xo7ASDAldo-keto reductase family 1 member C2/0.472
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.471
1n95FTHProtein farnesyltransferase subunit beta2.5.1.580.471
2aouCQAHistamine N-methyltransferase2.1.1.80.471
2xiq5ADMethylmalonyl-CoA mutase, mitochondrial/0.471
2z1qFADAcyl-CoA dehydrogenase/0.471
2qimZEAClass 10 plant pathogenesis-related protein/0.470
3iu7FCDMethionine aminopeptidase 2/0.470
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.470
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.470
1qjfACSIsopenicillin N synthase1.21.3.10.469
2fxuBIDActin, alpha skeletal muscle/0.469
2wu4HBPAcetylcholinesterase3.1.1.70.469
3c3xNAPEugenol synthase 11.1.1.3180.469
3inrGDUUDP-galactopyranose mutase5.4.99.90.469
3junAKDPhenazine biosynthesis protein A/B/0.469
4bfuZVUPantothenate kinase2.7.1.330.469
4e0u0MVCyclic dipeptide N-prenyltransferase/0.469
4u163C0Muscarinic acetylcholine receptor M3/0.469
2f0y3MNProtein farnesyltransferase subunit beta2.5.1.580.468
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.468
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.468
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.468
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.468
3u5ySCGRaucaffricine-O-beta-D-glucosidase3.2.1.1250.468
4dvi2IWTankyrase-12.4.2.300.468
4mqt2CUMuscarinic acetylcholine receptor M2/0.468
2g25TDKPyruvate dehydrogenase E1 component1.2.4.10.467
2iejS48Protein farnesyltransferase subunit beta2.5.1.580.467
2wzySQXSoluble acetylcholine receptor/0.467
3gf4UPGUDP-galactopyranose mutase5.4.99.90.467
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.467
3nmpPYVAbscisic acid receptor PYL2/0.467
3zkuHCVIsopenicillin N synthase1.21.3.10.467
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.467
4jlm1NNDeoxycytidine kinase2.7.1.740.467
1by5GLY_GLY_GLY_AHO_AHO_AHO_FEFerrichrome-iron receptor/0.466
2cmfF11Acetylcholinesterase3.1.1.70.466
2gv8NDPThiol-specific monooxygenase1.14.130.466
2hpsCTZCa2+-triggered coelenterazine-binding protein 1/0.466
2ixkTDOdTDP-4-dehydrorhamnose 3,5-epimerase5.1.3.130.466
3c1tMYCDihydroflavonol 4-reductase1.1.1.2190.466
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.466
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.466
5stdUNNScytalone dehydratase4.2.1.940.466
1hb3SCVIsopenicillin N synthase1.21.3.10.465
1o1t2NHProtein farnesyltransferase subunit beta2.5.1.580.465
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.465
1r2jFADFkbI/0.465
1yw9A84Methionine aminopeptidase 2/0.465
2jfhLK1UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.465
2uxoTACHTH-type transcriptional regulator TtgR/0.465
2xuqTZ4Acetylcholinesterase3.1.1.70.465
3dopNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.465
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.465
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.465
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.464
1jumBERHTH-type transcriptional regulator QacR/0.464
2g263LGRenin3.4.23.150.464
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.464
3h3t16HCollagen type IV alpha-3-binding protein/0.464
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.464
5c1mCLRMu-type opioid receptor/0.464
1x1bSAHC-20 methyltransferase/0.463
2fapRADPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.463
2fapRADSerine/threonine-protein kinase mTOR2.7.11.10.463
2xlpNAPPutative flavin-containing monooxygenase/0.463
2xukTZ5Acetylcholinesterase3.1.1.70.463
3br3ETHTH-type transcriptional regulator QacR/0.463
3h3qH13Collagen type IV alpha-3-binding protein/0.463
3mytEQUSteroid Delta-isomerase5.3.3.10.463
3zj7C1KStrictosidine-O-beta-D-glucosidase3.2.1.1050.463
4a86H35Major pollen allergen Bet v 1-A/0.463
4bfxZVXPantothenate kinase2.7.1.330.463
2rh1CAUBeta-2 adrenergic receptor/0.463
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.462
3ekuCY9Actin-5C/0.462
3f3y4OABile salt sulfotransferase2.8.2.140.462
3uyk0CXProbable NDP-rhamnosyltransferase/0.462
4dch4DCGlucokinase2.7.1.20.462
4qofFMNRibosyldihydronicotinamide dehydrogenase [quinone]/0.462
1itzTPPTransketolase, chloroplastic2.2.1.10.461
1pz1NAPGeneral stress protein 69/0.461
1ut6A8NAcetylcholinesterase3.1.1.70.461
3eq02TSProthrombin3.4.21.50.461
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.461
4drjRAPSerine/threonine-protein kinase mTOR2.7.11.10.461
4drjRAPPeptidyl-prolyl cis-trans isomerase FKBP45.2.1.80.461
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.461
1ihiIU5Aldo-keto reductase family 1 member C2/0.460
1jcq739Protein farnesyltransferase subunit beta2.5.1.580.460
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.460
2jl1NAPTriphenylmethane reductase/0.460
2vqqTFGHistone deacetylase 43.5.1.980.460
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.460
3casASD3-oxo-5-beta-steroid 4-dehydrogenase/0.460
3dr7GPDGDP-perosamine synthase/0.460
3g72A6TRenin3.4.23.150.460
3pkaY02Methionine aminopeptidase 2/0.460
4xwtU5PRibonuclease J/0.460
1yw8A75Methionine aminopeptidase 2/0.459
2fs4PZ1Renin3.4.23.150.459
2q94A04Methionine aminopeptidase/0.459
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.459
3dr4G4MGDP-perosamine synthase/0.459
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
3e33ED7Protein farnesyltransferase subunit beta2.5.1.580.459
3iu8T03Methionine aminopeptidase 2/0.459
4araC56Acetylcholinesterase3.1.1.70.459
4jtrIBPAldo-keto reductase family 1 member C2/0.459
4n9qFMNFMN-dependent NADH-azoreductase 1/0.459
4qa0SHHHistone deacetylase 83.5.1.980.459
1efyBZCPoly [ADP-ribose] polymerase 12.4.2.300.458
1mrqSTRAldo-keto reductase family 1 member C1/0.458
1nqvLMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.458
1r58AO5Methionine aminopeptidase 2/0.458
1zgcA2EAcetylcholinesterase3.1.1.70.458
2gg0U11Methionine aminopeptidase/0.458
2h3wHC5Carnitine O-acetyltransferase2.3.1.70.458
2vutNADNitrogen metabolite repression protein nmrA/0.458
2xugTZ4Acetylcholinesterase3.1.1.70.458
3djlFADPutative acyl-CoA dehydrogenase AidB1.3.990.458
3wqmB29Diterpene synthase3.1.7.80.458
4bfwZVWPantothenate kinase2.7.1.330.458
4h6pFMNChromate reductase/0.458
4qzuRTLRetinol-binding protein 2/0.458
5agyGTBTau class glutathione S-transferase/0.458
2a0xDIHPurine nucleoside phosphorylase2.4.2.10.457
2aovC2MHistamine N-methyltransferase2.1.1.80.457
3cgtBCDCyclomaltodextrin glucanotransferase2.4.1.190.457
3mjrAC2Deoxycytidine kinase2.7.1.740.457
4a87NARMajor pollen allergen Bet v 1-A/0.457
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.457
4uy6SAHHistidine N-alpha-methyltransferase/0.457
5d5aCAUBeta-2 adrenergic receptor/0.457
1eioGCHGastrotropin/0.456
1el4CTZObelin/0.456
1tcoFK5Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.456
1tcoFK5Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform3.1.3.160.456
2evmFC2Methionine aminopeptidase/0.456
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.456
3h3r14HCollagen type IV alpha-3-binding protein/0.456
3ivcFG4Pantothenate synthetase6.3.2.10.456
3tvqDQHMultifunctional cyclase-dehydratase-3-O-methyl transferase TcmN2.1.10.456
3voiRCBGlucanase/0.456
4flkY10Methionine aminopeptidase 1/0.456
4mk828QGenome polyprotein2.7.7.480.456
4nv1TYDFormyl transferase/0.456
5jscFADPutative acyl-CoA dehydrogenase/0.456
5d5bCAUBeta-2 adrenergic receptor/0.456
2g6pHM2Methionine aminopeptidase 1/0.455
2ga2A19Methionine aminopeptidase 2/0.455
2r8pT6FTransketolase 1/0.455
2whqHI6Acetylcholinesterase3.1.1.70.455
2xlrNAPPutative flavin-containing monooxygenase/0.455
2xvhNAPPutative flavin-containing monooxygenase/0.455
2zgb21UProthrombin3.4.21.50.455
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
3mj4URMUDP-galactopyranose mutase/0.455
3uayADNPurine nucleoside phosphorylase DeoD-type/0.455
3v0o4GWHisto-blood group ABO system transferase/0.455
4fam0SZAldo-keto reductase family 1 member C3/0.455
4jzr4JREgl nine homolog 1/0.455
4usqFADPyridine nucleotide-disulfide oxidoreductase/0.455
5ah5LSSLeucine--tRNA ligase/0.455
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.454
1paxDHQPoly [ADP-ribose] polymerase 12.4.2.300.454
1pke2FDPurine nucleoside phosphorylase DeoD-type/0.454
1pqc444Oxysterols receptor LXR-beta/0.454
1rkwPNTHTH-type transcriptional regulator QacR/0.454
1x8lOXRRetinol dehydratase/0.454
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.454
2evcFC3Methionine aminopeptidase/0.454
2g1r3IGRenin3.4.23.150.454
2jb4A14Isopenicillin N synthase1.21.3.10.454
2vbdV10Isopenicillin N synthase1.21.3.10.454
3akn11DFatty acid-binding protein, intestinal/0.454
3d27W29Methionine aminopeptidase/0.454
3mauPLRPutative sphingosine-1-phosphate lyase/0.454
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.454
1hrvSDZGenome polyprotein/0.453
2flhZEACytokinin-specific binding protein/0.453
2iviACWIsopenicillin N synthase1.21.3.10.453
2wmdZZ0NmrA-like family domain-containing protein 1/0.453
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.453
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.453
3p8iFMNPentaerythritol tetranitrate reductase/0.453
4bb2STRCorticosteroid-binding globulin/0.453
4cdmFO1Deoxyribodipyrimidine photolyase/0.453
4ey6GNTAcetylcholinesterase3.1.1.70.453
4jt91NSNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.453
1a9p9DIPurine nucleoside phosphorylase2.4.2.10.452
1m2xMCOMetallo-beta-lactamase type 2/0.452
1pfyMSPMethionine--tRNA ligase6.1.1.100.452
1swgBTNStreptavidin/0.452
2ed4NAD4-hydroxyphenylacetate 3-monooxygenase reductase component1.5.1.360.452
2xujTZ5Acetylcholinesterase3.1.1.70.452
3arvSAUChitinase A/0.452
3b1dPLSBetaC-S lyase/0.452
3qi4IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
4mk728OGenome polyprotein2.7.7.480.452
5irnADPNucleotide binding oligomerization domain containing 2/0.452
7stdCRPScytalone dehydratase4.2.1.940.452
1gky5GPGuanylate kinase2.7.4.80.451
1h66RH1NAD(P)H dehydrogenase [quinone] 11.6.5.20.451
1s7gNADNAD-dependent protein deacylase 2/0.451
1u2rSO1Elongation factor 2/0.451
1z8962PAldose reductase1.1.1.210.451
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.451
2gfxPMN3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.451
2gg3U13Methionine aminopeptidase/0.451
3c72CX1Geranylgeranyl transferase type-2 subunit beta2.5.1.600.451
3cv6HXSAldo-keto reductase family 1 member C21/0.451
3pkdY10Methionine aminopeptidase 2/0.451
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.451
4jbsP52Endoplasmic reticulum aminopeptidase 23.4.110.451
4l0qNADAlcohol dehydrogenase class-3/0.451
4wx2F6FTryptophan synthase alpha chain/0.451
4wx2F6FTryptophan synthase beta chain4.2.1.200.451
1d6w00RProthrombin3.4.21.50.450
1egeFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.450
1oc1ASVIsopenicillin N synthase1.21.3.10.450
2fvlNAPAldo-keto reductase family 1 member C41.1.1.2250.450
2ggbU17Methionine aminopeptidase/0.450
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.450
2rds1PL1-deoxypentalenic acid 11-beta-hydroxylase1.14.11.350.450
2xq0BESLeukotriene A-4 hydrolase homolog3.3.2.60.450
2zi53L1Deoxycytidine kinase2.7.1.740.450
3a25SAMtRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase/0.450
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
3gjwGJWPoly [ADP-ribose] polymerase 12.4.2.300.450
3gx9TXDMorphinone reductase/0.450
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.450
4iktTFVMethionine aminopeptidase 1/0.450
4jq3ZOMAldo-keto reductase family 1 member C2/0.450
4qa2SHHHistone deacetylase 83.5.1.980.450
4yfy0FXVioF/0.450
1fm4DXCMajor pollen allergen Bet v 1-L/0.449
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.449
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.449
1upw444Oxysterols receptor LXR-beta/0.449
2hzqSTRApolipoprotein D/0.449
2ikuLIYRenin3.4.23.150.449
2y6fM9FIsopenicillin N synthase1.21.3.10.449
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.449
3kslSZHProtein farnesyltransferase subunit beta2.5.1.580.449
3l3lL3LPoly [ADP-ribose] polymerase 12.4.2.300.449
3ziaADPATP synthase subunit beta, mitochondrial3.6.3.140.449
3zv7NHGAcetylcholinesterase3.1.1.70.449
4iksTFDMethionine aminopeptidase 1/0.449
4lcnGNGCytidine and deoxycytidylate deaminase zinc-binding region/0.449
4uugPXGBranched-chain amino acid aminotransferase, putative/0.449
1blzACVIsopenicillin N synthase1.21.3.10.448
1fmjRTLRetinol dehydratase/0.448
1fmlRTLRetinol dehydratase/0.448
1nsgRADPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.448
1nsgRADSerine/threonine-protein kinase mTOR2.7.11.10.448
1pq944BOxysterols receptor LXR-beta/0.448
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.448
2ejzSAHDiphthine synthase/0.448
2f3815MAldo-keto reductase family 1 member C3/0.448
2il2LIXRenin3.4.23.150.448
2npfMOUElongation factor 2/0.448
2oz57XYUncharacterized protein/0.448
3e30ED4Protein farnesyltransferase subunit beta2.5.1.580.448
3jusBCDLanosterol 14-alpha demethylase1.14.13.700.448
4kq6DLZ6,7-dimethyl-8-ribityllumazine synthase/0.448
4x7zZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.448
4zvnFADRibosyldihydronicotinamide dehydrogenase [quinone]/0.448
1b8oIMHPurine nucleoside phosphorylase2.4.2.10.447
1kw6BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.447
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.447
1ry8RUTAldo-keto reductase family 1 member C3/0.447
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.447
2bu9HFVIsopenicillin N synthase1.21.3.10.447
2pnjCHDFerrochelatase, mitochondrial4.99.1.10.447
2xpc051UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.447
2xveFADPutative flavin-containing monooxygenase/0.447
3aiqHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic3.2.1.1820.447
3fapARDPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.447
3fapARDSerine/threonine-protein kinase mTOR2.7.11.10.447
3ho9N3A3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.447
3iogSDFMetallo-beta-lactamase type 2/0.447
3nu03TUDihydrofolate reductase1.5.1.30.447
3nubUD0UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.447
3nx2FERFerulic acid decarboxylase/0.447
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.447
3qe2FMNNADPH--cytochrome P450 reductase/0.447
3tjlFMNNADPH dehydrogenase/0.447
4b2gV1NUncharacterized protein/0.447
4gd40WSLysine-specific demethylase 4A1.14.110.447
4jtrIZPAldo-keto reductase family 1 member C2/0.447
4qij1HA1,4-dihydroxy-2-naphthoyl-CoA synthase/0.447
1akcPPEAspartate aminotransferase, mitochondrial2.6.1.10.446
1amoFMNNADPH--cytochrome P450 reductase/0.446
1jqdSAHHistamine N-methyltransferase2.1.1.80.446
1qzyTDEMethionine aminopeptidase 2/0.446
1thz326Bifunctional purine biosynthesis protein PURH2.1.2.30.446
1w76GNTAcetylcholinesterase3.1.1.70.446
1xuzMMNCapsule biosynthesis protein/0.446
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.446
2f99AKVAklanonic acid methyl ester cyclase AcmA5.5.1.230.446
2g5w8PG12-oxophytodienoate reductase 31.3.1.420.446
2vqoTFGHistone deacetylase 43.5.1.980.446
3lq4TDPPyruvate dehydrogenase E1 component1.2.4.10.446
4bfzZVZPantothenate kinase2.7.1.330.446
1eirBPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.445
1mzcBNEProtein farnesyltransferase subunit beta2.5.1.580.445
2p98YE7Methionine aminopeptidase/0.445
2xuiTZ5Acetylcholinesterase3.1.1.70.445
2xvfFADPutative flavin-containing monooxygenase/0.445
2y1x845Histone-arginine methyltransferase CARM1/0.445
2ydd2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.445
3gluLYS_VAL_METNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.445
4a2zVIQGlycylpeptide N-tetradecanoyltransferase/0.445
4bfsZVSPantothenate kinase2.7.1.330.445
4dbs0HVAldo-keto reductase family 1 member C3/0.445
4h7c10HAldo-keto reductase family 1 member C3/0.445
4ttjFMCPurine nucleoside phosphorylase DeoD-type/0.445
5cxv0HKMuscarinic acetylcholine receptor M1/0.445
1sa5BMVProtein farnesyltransferase subunit beta2.5.1.580.444
1t41ID5Aldose reductase1.1.1.210.444
1zdwFLVPrenyltransferase/0.444
2ifaFMNUncharacterized protein/0.444
2q92B23Methionine aminopeptidase/0.444
2v3oI26Prothrombin3.4.21.50.444
2vqbNAPPutative flavin-containing monooxygenase/0.444
2x1hX1HProstaglandin reductase 310.444
2x9dITCTetracycline repressor protein class D/0.444
2zevIPEGeranylgeranyl pyrophosphate synthase/0.444
3ai0PNWBeta-glucosidase/0.444
3aivHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic3.2.1.1820.444
3ggs2FDPurine nucleoside phosphorylase2.4.2.10.444
3nxyD2HDihydrofolate reductase1.5.1.30.444
3zg6APRNAD-dependent protein deacetylase sirtuin-63.5.10.444
4a83DXCMajor pollen allergen Bet v 1-A/0.444
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.444
4bfyZVYPantothenate kinase2.7.1.330.444
4fllYZ6Methionine aminopeptidase 1/0.444
4g1cCNANAD-dependent protein deacylase sirtuin-5, mitochondrial/0.444
4jqaID8Aldo-keto reductase family 1 member C2/0.444
4jsr1NQNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.444
4mlp2CXCryptochrome-2/0.444
4pnmNU1Tankyrase-22.4.2.300.444
5jr34MUCarminomycin 4-O-methyltransferase DnrK2.1.1.2920.444
1afsTES3-alpha-hydroxysteroid dehydrogenase1.1.1.500.443
1nzq162Prothrombin3.4.21.50.443
1o1s1NHProtein farnesyltransferase subunit beta2.5.1.580.443
1oj4CDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.443
1tilATPAnti-sigma F factor/0.443
2bn4FMNNADPH--cytochrome P450 reductase/0.443
2hrcCHDFerrochelatase, mitochondrial4.99.1.10.443
2i65NADADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.443
2nvdITBAldose reductase1.1.1.210.443
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.443
2oatPFMOrnithine aminotransferase, mitochondrial2.6.1.130.443
2uuoLK3UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.443
2vcmM11Isopenicillin N synthase1.21.3.10.443
2xnvVU3Soluble acetylcholine receptor/0.443
2zsaADPPantothenate kinase2.7.1.330.443
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3lxeTORCarbonic anhydrase 14.2.1.10.443
4kfqKFQGlutamate receptor ionotropic, NMDA 1/0.443
4rr7A3SProbable threonine--tRNA ligase 26.1.1.30.443
1ef92CPMethylmalonyl-CoA decarboxylase4.1.1.410.442
1fxvPNNPenicillin G acylase3.5.1.110.442
1g63FMNEpidermin decarboxylase4.1.10.442
1gpnHUBAcetylcholinesterase3.1.1.70.442
1jf0CZHObelin/0.442
1m13HYFNuclear receptor subfamily 1 group I member 2/0.442
1pr0NOSPurine nucleoside phosphorylase DeoD-type/0.442
1rftPXMPyridoxal kinase2.7.1.350.442
1trkTPPTransketolase 12.2.1.10.442
1y2bDEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.442
1yw7A41Methionine aminopeptidase 2/0.442
2futH1SHeparin and heparin-sulfate lyase/0.442
2ok8FADFerredoxin--NADP reductase, apicoplast/0.442
2qmyFADRibosyldihydronicotinamide dehydrogenase [quinone]/0.442
2r6jNDPEugenol synthase 11.1.1.3180.442
2wsa646Glycylpeptide N-tetradecanoyltransferase/0.442
2z4w749Geranylgeranyl pyrophosphate synthase/0.442
3e32ED2Protein farnesyltransferase subunit beta2.5.1.580.442
3elePLPAminotransferase/0.442
3frkTQPQdtB/0.442
3gb4D3MDdmC/0.442
3mauEXTPutative sphingosine-1-phosphate lyase/0.442
3q9bB3NAcetylpolyamine amidohydrolase/0.442
3r8hZOMAldo-keto reductase family 1 member C3/0.442
3sfh1DIHistone deacetylase 83.5.1.980.442
4b63NAPL-ornithine N(5)-monooxygenase/0.442
4da7AC2Purine nucleoside phosphorylase DeoD-type2.4.2.10.442
4driRAPSerine/threonine-protein kinase mTOR2.7.11.10.442
4driRAPPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.442
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.442
4jt81NRNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.442
4xbjIN5Alanine racemase, biosynthetic/0.442
2ycxP32Beta-1 adrenergic receptor/0.442
4daj0HKMuscarinic acetylcholine receptor M3/0.442
1lkdBP6Biphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.441
1xmmM7Gm7GpppX diphosphatase3.6.1.590.441
3arpDEQChitinase A/0.441
3buvNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.441
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.580.441
3hbfMYCFlavonoid 3-O-glucosyltransferase2.4.10.441
3intGDUUDP-galactopyranose mutase5.4.99.90.441
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3ppr4CSGlycine betaine/carnitine/choline-binding protein OpuCC/0.441
3v0m5GWHisto-blood group ABO system transferase/0.441
3zhtTD9Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.441
4b64NAPL-ornithine N(5)-monooxygenase/0.441
4g2yNI5cGMP-specific 3',5'-cyclic phosphodiesterase/0.441
4kxjP34Nucleoprotein/0.441
4zj8SUVOrexin receptor type 1/0.441
1q84TZ4Acetylcholinesterase3.1.1.70.440
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.440
1sweBTNStreptavidin/0.440
1t9gFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.440
1w6rGNTAcetylcholinesterase3.1.1.70.440
1z3n3NAAldose reductase1.1.1.210.440
2c9zQUEAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.440
2g21L1BRenin3.4.23.150.440
2g28TDKPyruvate dehydrogenase E1 component1.2.4.10.440
2yp0OVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.440
3dhcCYKN-acyl homoserine lactonase AiiA3.1.1.810.440
3ogkOGKCoronatine-insensitive protein 1/0.440
3zhuTD8Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.440
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.440
4b4vL34Bifunctional protein FolD/0.440
4c2z646Glycylpeptide N-tetradecanoyltransferase 1/0.440
6stdMS2Scytalone dehydratase4.2.1.940.440