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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/1.000
3buvNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.700
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.648
3g1rNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.576
3caqNDP3-oxo-5-beta-steroid 4-dehydrogenase/0.568
3dopNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.564
2fvlNAPAldo-keto reductase family 1 member C41.1.1.2250.517
2hdjNDPAldo-keto reductase family 1 member C2/0.501
3h7rNAPAldo-keto reductase family 4 member C8/0.497
4jtqNAPAldo-keto reductase family 1 member C2/0.492
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.489
4jq3NAPAldo-keto reductase family 1 member C2/0.488
1s1rNAPAldo-keto reductase family 1 member C3/0.486
4xo7NAPAldo-keto reductase family 1 member C2/0.486
4dz5NAPAldo-keto reductase family 1 member C3/0.471
2hejNDPAldo-keto reductase family 1 member C211.1.10.466
4ijrNDPD-arabinose dehydrogenase [NAD(P)+] heavy chain1.1.1.1170.458
4l1xNAPAldo-keto reductase family 1 member C2/0.457
4pmjNAPPutative oxidoreductase/0.444
1lwiNAP3-alpha-hydroxysteroid dehydrogenase1.1.1.500.443