Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 1.000 | |
| 3qg2 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.741 | |
| 3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.740 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.654 | |
| 4h96 | 14Q | Dihydrofolate reductase | 1.5.1.3 | 0.645 | |
| 2bla | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.641 | |
| 3qly | 55V | Uncharacterized protein | / | 0.640 | |
| 4ixe | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.640 | |
| 3cse | N22 | Uncharacterized protein | / | 0.638 | |
| 1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.636 | |
| 3qfx | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.635 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.627 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.625 | |
| 1m78 | CLZ | Dihydrofolate reductase | 1.5.1.3 | 0.621 | |
| 3qlr | QLR | Dihydrofolate reductase | 1.5.1.3 | 0.621 | |
| 2blc | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.620 | |
| 3qls | 55V | Dihydrofolate reductase | 1.5.1.3 | 0.620 | |
| 3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.616 | |
| 1dg5 | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.613 | |
| 3qlz | QLZ | Uncharacterized protein | / | 0.613 | |
| 1rx3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.610 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.610 | |
| 1j3i | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.608 | |
| 3dg8 | RJ6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.606 | |
| 3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.606 | |
| 1aoe | GW3 | Dihydrofolate reductase | 1.5.1.3 | 0.605 | |
| 3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.605 | |
| 1ia1 | TQ3 | Dihydrofolate reductase | 1.5.1.3 | 0.603 | |
| 1dg7 | WRB | Dihydrofolate reductase | 1.5.1.3 | 0.600 | |
| 2blb | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.600 | |
| 1cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.598 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.598 | |
| 2cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.596 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.594 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.593 | |
| 3dga | RJ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.593 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.592 | |
| 3qlw | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.591 | |
| 4h98 | 14Q | Uncharacterized protein | / | 0.591 | |
| 3um8 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.588 | |
| 1m7a | MQU | Dihydrofolate reductase | 1.5.1.3 | 0.585 | |
| 4dph | P65 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.585 | |
| 1vj3 | TAB | Dihydrofolate reductase | 1.5.1.3 | 0.581 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.580 | |
| 2fzh | DH1 | Dihydrofolate reductase | 1.5.1.3 | 0.578 | |
| 1boz | PRD | Dihydrofolate reductase | 1.5.1.3 | 0.575 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.573 | |
| 3qlx | QLR | Uncharacterized protein | / | 0.573 | |
| 4xe6 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.572 | |
| 1ddr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.571 | |
| 1j3k | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.570 | |
| 3tq9 | MTX | Dihydrofolate reductase | / | 0.570 | |
| 1hfp | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.569 | |
| 1m79 | MQ1 | Dihydrofolate reductase | 1.5.1.3 | 0.568 | |
| 3k47 | D09 | Dihydrofolate reductase | 1.5.1.3 | 0.568 | |
| 3td8 | D2R | Dihydrofolate reductase | 1.5.1.3 | 0.568 | |
| 3eek | 53S | Uncharacterized protein | / | 0.567 | |
| 1ia2 | TQ4 | Dihydrofolate reductase | 1.5.1.3 | 0.566 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.565 | |
| 2fzi | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.565 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.564 | |
| 4x5f | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.564 | |
| 5ccc | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.564 | |
| 3dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.563 | |
| 4m6l | 21V | Dihydrofolate reductase | 1.5.1.3 | 0.563 | |
| 3eem | 53V | Uncharacterized protein | / | 0.562 | |
| 4m2x | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.559 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.557 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.557 | |
| 2w3v | TOP | Dihydrofolate reductase | / | 0.556 | |
| 1e26 | GPB | Dihydrofolate reductase | 1.5.1.3 | 0.554 | |
| 3jsu | KA5 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.554 | |
| 4ixg | IXG | Dihydrofolate reductase | 1.5.1.3 | 0.552 | |
| 4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.552 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.550 | |
| 3sa1 | 6DR | Dihydrofolate reductase | / | 0.550 | |
| 3sh2 | 5DR | Dihydrofolate reductase | 1.5.1.3 | 0.550 | |
| 4g8z | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.550 | |
| 2zza | FOL | Dihydrofolate reductase | / | 0.548 | |
| 4dp3 | MMV | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.547 | |
| 3jwm | 5WB | Dihydrofolate reductase | / | 0.545 | |
| 1qzf | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.544 | |
| 2w3a | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.544 | |
| 3jwc | EKB | Dihydrofolate reductase | / | 0.543 | |
| 1dds | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.540 | |
| 3sai | 9DR | Dihydrofolate reductase | / | 0.540 | |
| 4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.540 | |
| 4p66 | MTX | Dihydrofolate reductase | / | 0.540 | |
| 3eel | 53T | Uncharacterized protein | / | 0.538 | |
| 4p68 | MTX | Dihydrofolate reductase | / | 0.538 | |
| 7dfr | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.538 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.536 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.535 | |
| 4fgg | 0U5 | Dihydrofolate reductase | 1.5.1.3 | 0.534 | |
| 4kfj | 1R0 | Dihydrofolate reductase | 1.5.1.3 | 0.534 | |
| 4nx6 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.534 | |
| 4fgh | 0U6 | Dihydrofolate reductase | 1.5.1.3 | 0.533 | |
| 1dyr | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.532 | |
| 3frf | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.532 | |
| 3ql3 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.532 | |
| 3jw5 | TOP | Dihydrofolate reductase | / | 0.531 | |
| 3tqb | FOL | Dihydrofolate reductase | / | 0.531 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.530 | |
| 3sgy | 06W | Dihydrofolate reductase | 1.5.1.3 | 0.530 | |
| 4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.529 | |
| 4nx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.529 | |
| 4x5j | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.529 | |
| 3l3r | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.528 | |
| 3nxo | D2B | Dihydrofolate reductase | 1.5.1.3 | 0.528 | |
| 4ixf | IXF | Dihydrofolate reductase | 1.5.1.3 | 0.528 | |
| 1ly3 | COG | Dihydrofolate reductase | 1.5.1.3 | 0.525 | |
| 2w3w | VG9 | Dihydrofolate reductase | / | 0.525 | |
| 3r33 | 6ME | Dihydrofolate reductase | 1.5.1.3 | 0.524 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.523 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.523 | |
| 3ia4 | MTX | Dihydrofolate reductase | / | 0.522 | |
| 1s3y | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.521 | |
| 2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.521 | |
| 1ohj | COP | Dihydrofolate reductase | 1.5.1.3 | 0.520 | |
| 3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.519 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.519 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.519 | |
| 4kjj | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.519 | |
| 3clb | TMQ | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.518 | |
| 3fyw | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.518 | |
| 4x5g | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.518 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.517 | |
| 3fre | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.517 | |
| 3nxv | D2F | Dihydrofolate reductase | 1.5.1.3 | 0.517 | |
| 4x5i | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.517 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.516 | |
| 1rb3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.516 | |
| 3srs | M23 | Dihydrofolate reductase | 1.5.1.3 | 0.515 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.514 | |
| 1kms | LIH | Dihydrofolate reductase | 1.5.1.3 | 0.514 | |
| 3i8a | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.514 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.513 | |
| 3sa2 | 7DR | Dihydrofolate reductase | / | 0.513 | |
| 3srq | Q19 | Dihydrofolate reductase | 1.5.1.3 | 0.513 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.512 | |
| 3ntz | 3TZ | Dihydrofolate reductase | 1.5.1.3 | 0.512 | |
| 1drb | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.511 | |
| 2chw | 039 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.511 | |
| 1tdr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.509 | |
| 1dre | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.508 | |
| 3ant | S82 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.508 | |
| 3rg9 | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.508 | |
| 4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.507 | |
| 1re7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.506 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.506 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.506 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.505 | |
| 1dra | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.505 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.505 | |
| 3frd | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.505 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.505 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.504 | |
| 3sqy | Q11 | Dihydrofolate reductase | 1.5.1.3 | 0.504 | |
| 4kd7 | 9DR | Dihydrofolate reductase | 1.5.1.3 | 0.504 | |
| 3nxr | D2D | Dihydrofolate reductase | 1.5.1.3 | 0.503 | |
| 4ej1 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.503 | |
| 4kne | 1CY | Dihydrofolate reductase | 1.5.1.3 | 0.503 | |
| 1dr4 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.501 | |
| 3tq8 | TOP | Dihydrofolate reductase | / | 0.501 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.500 | |
| 1hfr | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.500 | |
| 3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.500 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.500 | |
| 3dau | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.499 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.499 | |
| 3srr | Q20 | Dihydrofolate reductase | 1.5.1.3 | 0.499 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.499 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.498 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.498 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.498 | |
| 3dat | MTX | Dihydrofolate reductase | / | 0.497 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.497 | |
| 3nxt | D2E | Dihydrofolate reductase | 1.5.1.3 | 0.497 | |
| 4elb | 34S | Dihydrofolate reductase | / | 0.497 | |
| 4fhb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.497 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.497 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.496 | |
| 1ly4 | COQ | Dihydrofolate reductase | 1.5.1.3 | 0.496 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.496 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.496 | |
| 4elb | 34R | Dihydrofolate reductase | / | 0.496 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.496 | |
| 4x5h | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.496 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.495 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.495 | |
| 1ra2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.494 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.494 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.494 | |
| 1ek2 | CDU | Bifunctional epoxide hydrolase 2 | / | 0.493 | |
| 2fsz | OHT | Estrogen receptor beta | / | 0.493 | |
| 3ghw | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.492 | |
| 5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.492 | |
| 1bzf | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.491 | |
| 1xp9 | AIJ | Estrogen receptor | / | 0.491 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.491 | |
| 3ue4 | DB8 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.491 | |
| 2w3m | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.490 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.490 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.490 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.490 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.490 | |
| 3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.489 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.489 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.489 | |
| 1ao8 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
| 1dyh | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
| 1rx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.488 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.488 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.488 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.487 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.487 | |
| 1s3w | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.487 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.487 | |
| 4iw8 | KN3 | Estrogen receptor | / | 0.487 | |
| 1dyi | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.486 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.486 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.486 | |
| 1rc4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.485 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.485 | |
| 3p9t | TCL | Repressor | / | 0.485 | |
| 3srw | Q27 | Dihydrofolate reductase | 1.5.1.3 | 0.485 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.484 | |
| 2c9d | PHR | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.484 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.484 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.484 | |
| 3qyo | Q24 | Dihydrofolate reductase | 1.5.1.3 | 0.484 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.484 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.483 | |
| 2p15 | EZT | Estrogen receptor | / | 0.483 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.483 | |
| 3nxy | D2H | Dihydrofolate reductase | 1.5.1.3 | 0.483 | |
| 1pq6 | 965 | Oxysterols receptor LXR-beta | / | 0.482 | |
| 1t47 | NTD | 4-hydroxyphenylpyruvate dioxygenase | 1.13.11.27 | 0.482 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.482 | |
| 4elg | 52J | Dihydrofolate reductase | / | 0.482 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.482 | |
| 4i13 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.482 | |
| 1rh3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.481 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.481 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.481 | |
| 4j26 | EST | Estrogen receptor beta | / | 0.481 | |
| 4lsj | LSJ | Glucocorticoid receptor | / | 0.481 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.481 | |
| 1l2i | ETC | Estrogen receptor | / | 0.480 | |
| 1vzd | CB3 | Thymidylate synthase | / | 0.480 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.480 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.480 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.480 | |
| 4fjy | FJY | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.480 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.479 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.479 | |
| 2fai | 459 | Estrogen receptor | / | 0.479 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.479 | |
| 3iqf | E4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.479 | |
| 3sr5 | Q12 | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.479 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.479 | |
| 1d2s | DHT | Sex hormone-binding globulin | / | 0.478 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.478 | |
| 1ra8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.478 | |
| 2w0b | CMW | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.478 | |
| 4l8u | 9AZ | Serum albumin | / | 0.478 | |
| 2m56 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.477 | |
| 2ocf | EST | Estrogen receptor | / | 0.477 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.477 | |
| 2y98 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.477 | |
| 3cv9 | VDX | Vitamin D3 dihydroxylase | / | 0.477 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.477 | |
| 4m7v | RAR | Dihydrofolate reductase | / | 0.477 | |
| 4ubs | DIF | Pentalenic acid synthase | 1.14.15.11 | 0.477 | |
| 1rx5 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 3ezp | B3N | Histone deacetylase 8 | 3.5.1.98 | 0.476 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.475 | |
| 3lnb | COA | N-acetyltransferase family protein | / | 0.475 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.475 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.475 | |
| 4ele | 31I | Dihydrofolate reductase | / | 0.475 | |
| 4hni | 16W | Casein kinase I isoform epsilon | 2.7.11.1 | 0.475 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.475 | |
| 4iui | 1GQ | Estrogen receptor | / | 0.475 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.474 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.474 | |
| 1rx2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.473 | |
| 3a4p | DFQ | Hepatocyte growth factor receptor | 2.7.10.1 | 0.473 | |
| 3iqz | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.473 | |
| 4bfr | J82 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | 2.7.1.153 | 0.473 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.473 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.473 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.472 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.472 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.472 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 3gyf | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.472 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.472 | |
| 1rx6 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 1ysx | 4EB | Serum albumin | / | 0.471 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.471 | |
| 2bj4 | OHT | Estrogen receptor | / | 0.471 | |
| 2qk8 | MTX | Dihydrofolate reductase | / | 0.471 | |
| 3ar5 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.471 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.471 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.471 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.471 | |
| 3sru | Q26 | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 4awo | 99B | Heat shock protein HSP 90-alpha | / | 0.471 | |
| 1ml6 | GBX | Glutathione S-transferase A2 | 2.5.1.18 | 0.470 | |
| 2jed | LG8 | Protein kinase C theta type | 2.7.11.13 | 0.470 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.470 | |
| 3cr7 | PPS | Adenylyl-sulfate kinase | 2.7.1.25 | 0.470 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.470 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.470 | |
| 4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.470 | |
| 1rd7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.469 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.469 | |
| 2g44 | T3O | Estrogen receptor | / | 0.469 | |
| 2w9g | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 2y30 | SM8 | Putative repressor SimReg2 | / | 0.469 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.469 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.469 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.469 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.469 | |
| 3mg3 | ECH | Orange carotenoid-binding protein | / | 0.469 | |
| 3oll | EST | Estrogen receptor beta | / | 0.469 | |
| 3pre | 3RE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.469 | |
| 4m6k | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 5hi6 | MTX | Dihydrofolate reductase | / | 0.469 | |
| 1krv | 147 | Galactoside O-acetyltransferase | 2.3.1.18 | 0.468 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.468 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.468 | |
| 1yqj | 6NP | Mitogen-activated protein kinase 14 | / | 0.468 | |
| 2fwz | H71 | Heat shock protein HSP 90-alpha | / | 0.468 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.468 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.468 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.468 | |
| 3w9r | A8S | Abscisic acid receptor PYL9 | / | 0.468 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.468 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.468 | |
| 4p6w | MOF | Glucocorticoid receptor | / | 0.468 | |
| 1qkn | RAL | Estrogen receptor beta | / | 0.467 | |
| 1s4d | SAH | Uroporphyrinogen-III C-methyltransferase | 2.1.1.107 | 0.467 | |
| 2b1z | 17M | Estrogen receptor | / | 0.467 | |
| 2jf9 | OHT | Estrogen receptor | / | 0.467 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.467 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.467 | |
| 3gie | ACP | Sensor histidine kinase DesK | 2.7.13.3 | 0.467 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.467 | |
| 4rra | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.467 | |
| 4v12 | POG | MaoC like domain protein | / | 0.467 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.467 | |
| 5d7q | 4I5 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.467 | |
| 1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.466 | |
| 1jra | FAD | FAD-linked sulfhydryl oxidase ERV2 | 1.8.3.2 | 0.466 | |
| 1rf7 | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.466 | |
| 1uhl | MEI | Retinoic acid receptor RXR-beta | / | 0.466 | |
| 1zky | 689 | Estrogen receptor | / | 0.466 | |
| 2npn | SAM | Putative cobalamin synthesis related protein | / | 0.466 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.466 | |
| 3fy8 | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 3neg | PYV | Abscisic acid receptor PYL1 | / | 0.466 | |
| 3q95 | ESL | Estrogen receptor | / | 0.466 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.466 | |
| 4qa1 | B3N | Histone deacetylase 8 | 3.5.1.98 | 0.466 | |
| 4rrm | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.466 | |
| 4xoq | F42 | Coenzyme F420:L-glutamate ligase | / | 0.466 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.465 | |
| 1f5f | DHT | Sex hormone-binding globulin | / | 0.465 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.465 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.465 | |
| 2b36 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.465 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.465 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 3fyv | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 3oq1 | 3OQ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.465 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 1c1b | GCA | Gag-Pol polyprotein | 2.7.7.49 | 0.464 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.464 | |
| 1dis | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1fml | RTL | Retinol dehydratase | / | 0.464 | |
| 1ra3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1s3v | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1tw4 | CHD | Fatty acid-binding protein, liver | / | 0.464 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.464 | |
| 2jfa | RAL | Estrogen receptor | / | 0.464 | |
| 2oax | SNL | Mineralocorticoid receptor | / | 0.464 | |
| 2ph5 | NAD | Homospermidine synthase | / | 0.464 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.464 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 3kb0 | A8S | Abscisic acid receptor PYL2 | / | 0.464 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.464 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.464 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.464 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.464 | |
| 3pwh | ZMA | Adenosine receptor A2a | / | 0.464 | |
| 1e6e | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.463 | |
| 1kmv | LII | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 1nzy | BCA | 4-chlorobenzoyl coenzyme A dehalogenase | 3.8.1.7 | 0.463 | |
| 1psd | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.463 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.463 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 1xpc | AIT | Estrogen receptor | / | 0.463 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.463 | |
| 2c94 | TSF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.463 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.463 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.463 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.463 | |
| 3lak | KR1 | Gag-Pol polyprotein | 2.7.7.49 | 0.463 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.463 | |
| 4fw0 | 5KJ | Nitric oxide synthase, brain | 1.14.13.39 | 0.463 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.463 | |
| 1ezf | IN0 | Squalene synthase | 2.5.1.21 | 0.462 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.462 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.462 | |
| 2apg | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.462 | |
| 2d0k | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.462 | |
| 2ntj | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.462 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.462 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.462 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 3aba | FLI | Cytochrome P450 | / | 0.462 | |
| 3ebf | 332 | Nitric oxide synthase, inducible | 1.14.13.39 | 0.462 | |
| 4dsb | A8S | Abscisic acid receptor PYL3 | / | 0.462 | |
| 1enz | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 1jom | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.461 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 2nnh | REA | Cytochrome P450 2C8 | / | 0.461 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.461 | |
| 3a8w | ATP | Protein kinase C iota type | 2.7.11.13 | 0.461 | |
| 3wsb | RWZ | Farnesyltransferase, putative | / | 0.461 | |
| 3zsh | 469 | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.461 | |
| 4u0o | MTA | Lipoyl synthase 2 | / | 0.461 | |
| 5gcn | COA | HAT A1 | / | 0.461 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 2uxh | QUE | HTH-type transcriptional regulator TtgR | / | 0.460 | |
| 2ze2 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.460 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.460 | |
| 3iqe | F42 | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.460 | |
| 3tqa | NDP | Dihydrofolate reductase | / | 0.460 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.460 | |
| 4aos | NAP | Steroid monooxygenase | / | 0.460 | |
| 4c3y | ANB | 3-ketosteroid dehydrogenase | / | 0.460 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.460 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.460 | |
| 4i6f | 1C7 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.460 | |
| 4k9y | K9Y | Focal adhesion kinase 1 | 2.7.10.2 | 0.460 | |
| 4l9k | EHF | Serum albumin | / | 0.460 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.460 | |
| 4rbs | 0RV | Metallo-beta-lactamase type 2 | / | 0.460 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.460 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.459 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.459 | |
| 1gwr | EST | Estrogen receptor | / | 0.459 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 2g5o | DRQ | Estrogen receptor | / | 0.459 | |
| 2l98 | STL | Troponin C, slow skeletal and cardiac muscles | / | 0.459 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.459 | |
| 2q70 | DC8 | Estrogen receptor | / | 0.459 | |
| 2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.459 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.459 | |
| 3ngl | NAP | Bifunctional protein FolD | / | 0.459 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.459 | |
| 3zbn | COA | 3-ketoacyl-CoA thiolase-like protein | / | 0.459 | |
| 4j24 | EST | Estrogen receptor beta | / | 0.459 | |
| 4jf1 | PLP | Acetylornithine/succinyldiaminopimelate aminotransferase | 2.6.1.11 | 0.459 | |
| 4lb2 | DM5 | Serum albumin | / | 0.459 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.459 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.459 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 3uza | T4G | Adenosine receptor A2a | / | 0.459 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.458 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.458 | |
| 1xu7 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.458 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.458 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.458 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.458 | |
| 4bmp | FMN | Protein NrdI | / | 0.458 | |
| 4fk3 | 325 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.458 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.458 | |
| 4qjc | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.458 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.457 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.457 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 1yi4 | ADN | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.457 | |
| 1yim | CM4 | Estrogen receptor | / | 0.457 | |
| 2e98 | B29 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.457 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 2qe4 | JJ3 | Estrogen receptor | / | 0.457 | |
| 3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.457 | |
| 3fl8 | RAR | Dihydrofolate reductase | / | 0.457 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.457 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.457 | |
| 4ivy | 1GT | Estrogen receptor | / | 0.457 | |
| 4jvn | YUG | Estrogen sulfotransferase | 2.8.2.4 | 0.457 | |
| 4lga | A2O | Abscisic acid receptor PYL2 | / | 0.457 | |
| 4uga | Q05 | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.457 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.457 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 1nhz | 486 | Glucocorticoid receptor | / | 0.456 | |
| 1pd8 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1rx4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.456 | |
| 2cch | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.456 | |
| 2wkm | PFY | Hepatocyte growth factor receptor | 2.7.10.1 | 0.456 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 3fy9 | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.456 | |
| 3irx | UDR | Gag-Pol polyprotein | 2.7.7.49 | 0.456 | |
| 3k45 | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 3uvv | REA | Retinoic acid receptor RXR-alpha | / | 0.456 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 4fex | 0TO | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.456 | |
| 4gg7 | 0J8 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.456 | |
| 4rrh | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.456 | |
| 1lhw | ESM | Sex hormone-binding globulin | / | 0.455 | |
| 1o6r | R19 | Squalene--hopene cyclase | 4.2.1.129 | 0.455 | |
| 1uy8 | PU5 | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 1x7e | 244 | Estrogen receptor | / | 0.455 | |
| 2giu | FBR | Estrogen receptor beta | / | 0.455 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.455 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.455 | |
| 2yhd | TES | Androgen receptor | / | 0.455 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.455 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.455 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.455 | |
| 3oji | PYV | Abscisic acid receptor PYL3 | / | 0.455 | |
| 3tmz | 06X | Cytochrome P450 2B4 | 1.14.14.1 | 0.455 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.455 | |
| 4a7c | E46 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.455 | |
| 4ajw | VWN | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | 2.7.1.153 | 0.455 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.455 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.455 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 1kl2 | FON | Serine hydroxymethyltransferase | / | 0.454 | |
| 1uwh | BAX | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.454 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.454 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.454 | |
| 2b37 | 8PS | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 3sls | 77D | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.454 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.454 | |
| 4jr5 | 1LS | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.454 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.454 | |
| 5dx3 | EST | Estrogen receptor | / | 0.454 | |
| 1n4h | REA | Nuclear receptor ROR-beta | / | 0.453 | |
| 1nq7 | ARL | Nuclear receptor ROR-beta | / | 0.453 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.453 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.453 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 2ij7 | TPF | Mycocyclosin synthase | 1.14.21.9 | 0.453 | |
| 2j7y | E3O | Estrogen receptor beta | / | 0.453 | |
| 2nn7 | M29 | Carbonic anhydrase 1 | 4.2.1.1 | 0.453 | |
| 2q66 | ATP | Poly(A) polymerase | 2.7.7.19 | 0.453 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.453 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.453 | |
| 3fko | FKO | Mitogen-activated protein kinase 14 | / | 0.453 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.453 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.453 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.453 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 4dvq | 1CA | Cytochrome P450 11B2, mitochondrial | 1.14.15.4 | 0.453 | |
| 4few | PP2 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.453 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.453 | |
| 1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 1vrq | FON | Subunit alpha of sarocosine oxidase | / | 0.452 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 1w1r | ZEA | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.452 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 1yre | COA | Uncharacterized protein | / | 0.452 | |
| 2dqs | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.452 | |
| 2yjx | YJX | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 2zce | PYL | Pyrrolysine--tRNA ligase | / | 0.452 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.452 | |
| 3h1j | SMA | Cytochrome b | / | 0.452 | |
| 3iw8 | HIZ | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 3kp4 | MII | Transcriptional regulator TcaR | / | 0.452 | |
| 3qlh | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.452 | |
| 3tdl | 11D | Serum albumin | / | 0.452 | |
| 3uud | EST | Estrogen receptor | / | 0.452 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.452 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.452 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.452 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.452 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
| 4hvb | 19P | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1u2g | APR | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.451 | |
| 1vce | SAH | Diphthine synthase | / | 0.451 | |
| 2cle | F6F | Tryptophan synthase alpha chain | / | 0.451 | |
| 3csd | EMO | Putative ketoacyl reductase | 1.3.1 | 0.451 | |
| 3e6o | A55 | Nitric oxide synthase, inducible | 1.14.13.39 | 0.451 | |
| 3flz | FLZ | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
| 3gcq | 1BU | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 3hz1 | 42C | Heat shock protein HSP 90-alpha | / | 0.451 | |
| 3l03 | 4OH | Estrogen receptor | / | 0.451 | |
| 3lkh | LT6 | Genome polyprotein | 2.7.7.48 | 0.451 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4g1q | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.451 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.451 | |
| 5bt4 | 2LO | Bromodomain-containing protein 4 | / | 0.451 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 5dxg | EST | Estrogen receptor | / | 0.451 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.450 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.450 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.450 | |
| 1lud | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.450 | |
| 2bxo | OPB | Serum albumin | / | 0.450 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.450 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.450 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.450 | |
| 2o4j | VD4 | Vitamin D3 receptor | / | 0.450 | |
| 2p7z | OHT | Estrogen-related receptor gamma | / | 0.450 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.450 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.450 | |
| 2xtb | KRM | Adenosine kinase, putative | / | 0.450 | |
| 3b3p | JI7 | Nitric oxide synthase, brain | 1.14.13.39 | 0.450 | |
| 3erd | DES | Estrogen receptor | / | 0.450 | |
| 3ggg | NAD | Prephenate dehydrogenase | / | 0.450 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.450 | |
| 4at2 | ASD | Possible succinate dehydrogenase | / | 0.450 | |
| 4bcq | TJF | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 4dsc | A8S | Abscisic acid receptor PYL3 | / | 0.450 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.450 | |
| 4iv2 | 1GR | Estrogen receptor | / | 0.450 | |
| 4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.450 | |
| 4ug7 | 1EV | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.450 | |
| 4zas | TYD | CalS13 | / | 0.450 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.449 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.449 | |
| 1eio | GCH | Gastrotropin | / | 0.449 | |
| 1kij | NOV | DNA gyrase subunit B | / | 0.449 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.449 | |
| 1rjk | VDZ | Vitamin D3 receptor | / | 0.449 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 1xds | DRA | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.449 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2rkv | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.449 | |
| 3dge | ADP | Sensor histidine kinase | / | 0.449 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 3gob | HXX | DdmC | / | 0.449 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.449 | |
| 3qj5 | 022 | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.449 | |
| 3u8h | BHP | Phospholipase A2, membrane associated | / | 0.449 | |
| 3uf7 | ASP_ILE_PRO_PHE | Uracil-DNA glycosylase | 3.2.2.27 | 0.449 | |
| 3vhu | SNL | Mineralocorticoid receptor | / | 0.449 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.449 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 4czt | CPS | CBL-interacting serine/threonine-protein kinase 23 | 2.7.11.1 | 0.449 | |
| 4hnc | 0UT | Mandelate racemase | / | 0.449 | |
| 4jq7 | KJQ | Epidermal growth factor receptor | 2.7.10.1 | 0.449 | |
| 4m6p | 20R | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.449 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.448 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.448 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.448 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.448 | |
| 1g50 | EST | Estrogen receptor | / | 0.448 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.448 | |
| 1kt6 | RTL | Retinol-binding protein 4 | / | 0.448 | |
| 1p6j | DP9 | Nitric oxide synthase, brain | 1.14.13.39 | 0.448 | |
| 1rg7 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1yin | CM3 | Estrogen receptor | / | 0.448 | |
| 2yek | EAM | Bromodomain-containing protein 2 | / | 0.448 | |
| 2yx6 | ADP | Uncharacterized protein | / | 0.448 | |
| 3nef | PYV | Abscisic acid receptor PYL1 | / | 0.448 | |
| 3nks | ACJ | Protoporphyrinogen oxidase | 1.3.3.4 | 0.448 | |
| 3pm0 | BHF | Cytochrome P450 1B1 | / | 0.448 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 3zk5 | Z18 | Cytochrome P450 monooxygenase PikC | / | 0.448 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.448 | |
| 4mv4 | ACP | Biotin carboxylase | 6.3.4.14 | 0.448 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.448 | |
| 4xcv | NDP | Probable hydroxyacid dehydrogenase protein | / | 0.448 | |
| 5h8t | RTL | Retinol-binding protein 1 | / | 0.448 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.448 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.447 | |
| 1e1n | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.447 | |
| 1ove | 358 | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 1p44 | GEQ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 1tvr | TB9 | Gag-Pol polyprotein | 2.7.7.49 | 0.447 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 2bbq | PFG | Thymidylate synthase | / | 0.447 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 2iw8 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 2q7g | CCL | Pyrrolysine--tRNA ligase | / | 0.447 | |
| 2qbn | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 2vte | IK4 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.447 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.447 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.447 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.447 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.447 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 3dha | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.447 | |
| 3g5h | YTT | Mycocyclosin synthase | 1.14.21.9 | 0.447 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3ov4 | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.447 | |
| 3p6p | A6B | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 3qaq | QAQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.447 | |
| 3zv5 | BPY | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.447 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.447 | |
| 4gki | 0JN | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.447 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.447 | |
| 4jlk | 1NO | Deoxycytidine kinase | 2.7.1.74 | 0.447 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.447 | |
| 4lt6 | 3AT | Poly(A) polymerase gamma | 2.7.7.19 | 0.447 | |
| 4rr7 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.447 | |
| 1gwq | ZTW | Estrogen receptor | / | 0.446 | |
| 1i58 | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.446 | |
| 1jtq | LY3 | Thymidylate synthase | / | 0.446 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
| 1rdt | L79 | Retinoic acid receptor RXR-alpha | / | 0.446 | |
| 1rkg | VD1 | Vitamin D3 receptor | / | 0.446 | |
| 1sr7 | MOF | Progesterone receptor | / | 0.446 | |
| 2cdc | NAP | Glucose 1-dehydrogenase | / | 0.446 | |
| 2ejz | SAH | Diphthine synthase | / | 0.446 | |
| 2h42 | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.446 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.446 | |
| 3fnl | SHA | Lactoperoxidase | / | 0.446 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.446 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.446 | |
| 3sl2 | ATP | Sensor histidine kinase WalK | / | 0.446 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.446 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 4gkh | 0J9 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.446 | |
| 4iv4 | 1GS | Estrogen receptor | / | 0.446 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.446 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.446 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.446 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.446 | |
| 5d1b | TSN | Histone deacetylase 8 | 3.5.1.98 | 0.446 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.446 | |
| 3rfm | CFF | Adenosine receptor A2a | / | 0.446 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.445 | |
| 1dtp | APU | Diphtheria toxin | / | 0.445 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1enp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.445 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.445 | |
| 1jut | LYD | Thymidylate synthase | / | 0.445 | |
| 1r35 | I58 | Nitric oxide synthase, inducible | 1.14.13.39 | 0.445 | |
| 1rb2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1tl1 | H18 | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.445 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.445 | |
| 2iog | IOG | Estrogen receptor | / | 0.445 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.445 | |
| 2vx0 | 7X7 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.445 | |
| 2y37 | A54 | Nitric oxide synthase, inducible | 1.14.13.39 | 0.445 | |
| 2zd1 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
| 3ar7 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.445 | |
| 3gd3 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.445 | |
| 3t8x | T8X | T-cell surface glycoprotein CD1b | / | 0.445 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.445 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.445 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.445 | |
| 4elh | 53I | Dihydrofolate reductase | / | 0.445 | |
| 4j6i | 1JV | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4lwa | Q13 | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.445 | |
| 4mv3 | ACP | Biotin carboxylase | 6.3.4.14 | 0.445 | |
| 4o76 | 1M3 | Bromodomain-containing protein 4 | / | 0.445 | |
| 1bvr | THT | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1fm9 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.444 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.444 | |
| 1l2j | ETC | Estrogen receptor beta | / | 0.444 | |
| 1m9m | 6NI | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.444 | |
| 1sbr | VIB | Putative HMP/thiamine-binding protein YkoF | / | 0.444 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 1xj7 | DHT | Androgen receptor | / | 0.444 | |
| 1xp1 | AIH | Estrogen receptor | / | 0.444 | |
| 1yho | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 2acl | REA | Retinoic acid receptor RXR-alpha | / | 0.444 | |
| 2ehl | SAH | Diphthine synthase | / | 0.444 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.444 | |
| 2qgt | EED | Estrogen receptor | / | 0.444 | |
| 2uxu | NAR | HTH-type transcriptional regulator TtgR | / | 0.444 | |
| 2vrb | NAP | Triphenylmethane reductase | / | 0.444 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 3b99 | U51 | Prostacyclin synthase | / | 0.444 | |
| 3blr | CPB | Cyclin-dependent kinase 9 | 2.7.11.22 | 0.444 | |
| 3h0a | 9RA | Retinoic acid receptor RXR-alpha | / | 0.444 | |
| 3itz | P66 | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3jyq | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.444 | |
| 3new | 3NE | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.444 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.444 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.444 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.444 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.444 | |
| 4h6r | FDA | Proline dehydrogenase | / | 0.444 | |
| 4jvm | XDI | Estrogen sulfotransferase | 2.8.2.4 | 0.444 | |
| 4l4a | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.444 | |
| 1al8 | DHP | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.443 | |
| 1m8h | 6NI | Nitric oxide synthase, inducible | 1.14.13.39 | 0.443 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.443 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.443 | |
| 1sqb | AZO | Cytochrome b | / | 0.443 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1u71 | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 2bxm | IMN | Serum albumin | / | 0.443 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.443 | |
| 2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 2pui | ADP | Methylthioribose kinase | 2.7.1.100 | 0.443 | |
| 2pul | ACP | Methylthioribose kinase | 2.7.1.100 | 0.443 | |
| 2qo4 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.443 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 3e7t | B14 | Nitric oxide synthase, inducible | 1.14.13.39 | 0.443 | |
| 3gb4 | D3M | DdmC | / | 0.443 | |
| 3h6k | 33T | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 3zia | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.443 | |
| 3zqt | TES | Androgen receptor | / | 0.443 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.443 | |
| 4d7e | FAD | Putative lysine-N-oxygenase | / | 0.443 | |
| 4dma | 0L8 | Estrogen receptor | / | 0.443 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.443 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 4equ | G6I | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.443 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 4iah | 1DX | Alr2278 protein | / | 0.443 | |
| 4iw6 | 1GU | Estrogen receptor | / | 0.443 | |
| 4jnc | 1LF | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.443 | |
| 4yaf | 2AM | NADPH--cytochrome P450 reductase | / | 0.443 | |
| 1ahi | CHO | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.442 | |
| 1e8x | ATP | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 1xu9 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 2bak | AQZ | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 2fpc | SCG | Strictosidine synthase | 4.3.3.2 | 0.442 | |
| 2ykb | YKB | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 3d3e | D3E | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3eej | 53R | Uncharacterized protein | / | 0.442 | |
| 3ey9 | TDP | Pyruvate dehydrogenase [ubiquinone] | 1.2.5.1 | 0.442 | |
| 3ft8 | MOJ | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 3gkj | HC3 | Niemann-Pick C1 protein | / | 0.442 | |
| 3kdi | A8S | Abscisic acid receptor PYL2 | / | 0.442 | |
| 3qdd | 94M | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 4a9m | P9M | Bromodomain-containing protein 2 | / | 0.442 | |
| 4a9y | AQZ | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 4b5b | BBE | Glucose-1-phosphate thymidylyltransferase | / | 0.442 | |
| 4c9o | CAM | Cytochrome P450 | / | 0.442 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.442 | |
| 4ogr | ADN | Cyclin-dependent kinase 9 | 2.7.11.22 | 0.442 | |
| 4wa9 | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.442 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.442 | |
| 5hyr | EST | Estrogen receptor | / | 0.442 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1k74 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.441 | |
| 1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.441 | |
| 1ohk | COP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1rf9 | DBR | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.441 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 2azz | TCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.441 | |
| 2hm9 | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.441 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.441 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.441 | |
| 2rtm | IMI | Streptavidin | / | 0.441 | |
| 2yej | XQK | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 2ylp | TES | Androgen receptor | / | 0.441 | |
| 3bgr | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 3cqu | CQU | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.441 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.441 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 3lu8 | IQX | Serum albumin | / | 0.441 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.441 | |
| 3p6o | ETG | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.441 | |
| 4gh3 | 0EV | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.441 | |
| 4ktl | 1CQ | Cytochrome P450 | / | 0.441 | |
| 4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.441 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.441 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.441 | |
| 3rey | XAC | Adenosine receptor A2a | / | 0.441 | |
| 1cjc | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.440 | |
| 1kdm | DHT | Sex hormone-binding globulin | / | 0.440 | |
| 1pl8 | NAD | Sorbitol dehydrogenase | 1.1.1.14 | 0.440 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 1qnf | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.440 | |
| 1wrl | TFP | Troponin C, slow skeletal and cardiac muscles | / | 0.440 | |
| 1x7r | GEN | Estrogen receptor | / | 0.440 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.440 | |
| 2bxq | IMN | Serum albumin | / | 0.440 | |
| 2cda | NAP | Glucose 1-dehydrogenase | / | 0.440 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.440 | |
| 2j9g | ANP | Biotin carboxylase | 6.3.4.14 | 0.440 | |
| 2ouz | C3D | Estrogen receptor | / | 0.440 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.440 | |
| 3bqd | DAY | Glucocorticoid receptor | / | 0.440 | |
| 3d75 | NBB | Pheromone-binding protein ASP1 | / | 0.440 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 3njo | P2M | Abscisic acid receptor PYR1 | / | 0.440 | |
| 3ows | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.440 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.440 | |
| 3up0 | D7S | aceDAF-12 | / | 0.440 | |
| 3v4e | COA | Putative acetyltransferase SACOL2570 | 2.3.1 | 0.440 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.440 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.440 | |
| 3zrb | OR8 | Progesterone receptor | / | 0.440 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.440 | |
| 4eft | EFT | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 4ejg | NCT | Cytochrome P450 2A13 | 1.14.14.1 | 0.440 | |
| 4fad | 0TB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4feu | 537 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.440 | |
| 4gxs | 0YS | Glutamate receptor 2 | / | 0.440 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.440 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.440 | |
| 4lg5 | A1O | Abscisic acid receptor PYL2 | / | 0.440 | |
| 4lvb | 20N | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.440 |