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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3um5CP6Bifunctional dihydrofolate reductase-thymidylate synthase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3um5CP6Bifunctional dihydrofolate reductase-thymidylate synthase/1.000
3qg2CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.741
3um61CYBifunctional dihydrofolate reductase-thymidylate synthase/0.740
4h9506UDihydrofolate reductase1.5.1.30.654
4h9614QDihydrofolate reductase1.5.1.30.645
2blaCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.641
3qly55VUncharacterized protein/0.640
4ixeIXEDihydrofolate reductase1.5.1.30.640
3cseN22Uncharacterized protein/0.638
1j3jCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.636
3qfxCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.635
1klkPMDDihydrofolate reductase1.5.1.30.627
4h9753SDihydrofolate reductase1.5.1.30.625
1m78CLZDihydrofolate reductase1.5.1.30.621
3qlrQLRDihydrofolate reductase1.5.1.30.621
2blcCP7Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.620
3qls55VDihydrofolate reductase1.5.1.30.620
3iro2CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.616
1dg5TOPDihydrofolate reductase1.5.1.30.613
3qlzQLZUncharacterized protein/0.613
1rx3MTXDihydrofolate reductase1.5.1.30.610
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.610
1j3iWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.608
3dg8RJ6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.606
3qgtCP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.606
1aoeGW3Dihydrofolate reductase1.5.1.30.605
3invC50Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.605
1ia1TQ3Dihydrofolate reductase1.5.1.30.603
1dg7WRBDihydrofolate reductase1.5.1.30.600
2blbCP7Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.600
1cd2FOLDihydrofolate reductase1.5.1.30.598
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.598
2cd2FOLDihydrofolate reductase1.5.1.30.596
3kjsDQ1Bifunctional dihydrofolate reductase-thymidylate synthase/0.594
1hfqMOTDihydrofolate reductase1.5.1.30.593
3dgaRJ1Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.593
3irn1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.592
3qlwN22Dihydrofolate reductase1.5.1.30.591
4h9814QUncharacterized protein/0.591
3um81CYBifunctional dihydrofolate reductase-thymidylate synthase/0.588
1m7aMQUDihydrofolate reductase1.5.1.30.585
4dphP65Bifunctional dihydrofolate reductase-thymidylate synthase/0.585
1vj3TABDihydrofolate reductase1.5.1.30.581
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.580
2fzhDH1Dihydrofolate reductase1.5.1.30.578
1bozPRDDihydrofolate reductase1.5.1.30.575
3eigMTXDihydrofolate reductase1.5.1.30.573
3qlxQLRUncharacterized protein/0.573
4xe606UDihydrofolate reductase1.5.1.30.572
1ddrMTXDihydrofolate reductase1.5.1.30.571
1j3kWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.570
3tq9MTXDihydrofolate reductase/0.570
1hfpMOTDihydrofolate reductase1.5.1.30.569
1m79MQ1Dihydrofolate reductase1.5.1.30.568
3k47D09Dihydrofolate reductase1.5.1.30.568
3td8D2RDihydrofolate reductase1.5.1.30.568
3eek53SUncharacterized protein/0.567
1ia2TQ4Dihydrofolate reductase1.5.1.30.566
1dajMOTDihydrofolate reductase1.5.1.30.565
2fziDH3Dihydrofolate reductase1.5.1.30.565
1ia3TQ5Dihydrofolate reductase1.5.1.30.564
4x5fFOLDihydrofolate reductase1.5.1.30.564
5cccDDFDihydrofolate reductase1.5.1.30.564
3dfrMTXDihydrofolate reductase1.5.1.30.563
4m6l21VDihydrofolate reductase1.5.1.30.563
3eem53VUncharacterized protein/0.562
4m2xTMQDihydrofolate reductase1.5.1.30.559
1ia4TQ6Dihydrofolate reductase1.5.1.30.557
4cd2FOLDihydrofolate reductase1.5.1.30.557
2w3vTOPDihydrofolate reductase/0.556
1e26GPBDihydrofolate reductase1.5.1.30.554
3jsuKA5Bifunctional dihydrofolate reductase-thymidylate synthase/0.554
4ixgIXGDihydrofolate reductase1.5.1.30.552
4kak06UDihydrofolate reductase1.5.1.30.552
2cig1DGDihydrofolate reductase1.5.1.30.550
3sa16DRDihydrofolate reductase/0.550
3sh25DRDihydrofolate reductase1.5.1.30.550
4g8zTOPDihydrofolate reductase1.5.1.30.550
2zzaFOLDihydrofolate reductase/0.548
4dp3MMVBifunctional dihydrofolate reductase-thymidylate synthase/0.547
3jwm5WBDihydrofolate reductase/0.545
1qzfFOLBifunctional dihydrofolate reductase-thymidylate synthase/0.544
2w3aTOPDihydrofolate reductase1.5.1.30.544
3jwcEKBDihydrofolate reductase/0.543
1ddsMTXDihydrofolate reductase1.5.1.30.540
3sai9DRDihydrofolate reductase/0.540
4kebFOLDihydrofolate reductase1.5.1.30.540
4p66MTXDihydrofolate reductase/0.540
3eel53TUncharacterized protein/0.538
4p68MTXDihydrofolate reductase/0.538
7dfrFOLDihydrofolate reductase1.5.1.30.538
1dhfFOLDihydrofolate reductase1.5.1.30.536
3oafOAGDihydrofolate reductase1.5.1.30.535
4fgg0U5Dihydrofolate reductase1.5.1.30.534
4kfj1R0Dihydrofolate reductase1.5.1.30.534
4nx6FOLDihydrofolate reductase1.5.1.30.534
4fgh0U6Dihydrofolate reductase1.5.1.30.533
1dyrTOPDihydrofolate reductase1.5.1.30.532
3frfXCFDihydrofolate reductase1.5.1.30.532
3ql3FOLDihydrofolate reductase1.5.1.30.532
3jw5TOPDihydrofolate reductase/0.531
3tqbFOLDihydrofolate reductase/0.531
3nj0PYVAbscisic acid receptor PYL2/0.530
3sgy06WDihydrofolate reductase1.5.1.30.530
4kbn25UDihydrofolate reductase1.5.1.30.529
4nx7FOLDihydrofolate reductase1.5.1.30.529
4x5jFOLDihydrofolate reductase1.5.1.30.529
3l3rOAGDihydrofolate reductase1.5.1.30.528
3nxoD2BDihydrofolate reductase1.5.1.30.528
4ixfIXFDihydrofolate reductase1.5.1.30.528
1ly3COGDihydrofolate reductase1.5.1.30.525
2w3wVG9Dihydrofolate reductase/0.525
3r336MEDihydrofolate reductase1.5.1.30.524
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.523
4g95OAGDihydrofolate reductase1.5.1.30.523
3ia4MTXDihydrofolate reductase/0.522
1s3yTQTDihydrofolate reductase1.5.1.30.521
2fzjDH3Dihydrofolate reductase1.5.1.30.521
1ohjCOPDihydrofolate reductase1.5.1.30.520
3och2MXDihydrofolate reductase1.5.1.30.519
3s3vTOPDihydrofolate reductase1.5.1.30.519
4j6cSTRCytochrome P450 monooxygenase/0.519
4kjjFOLDihydrofolate reductase1.5.1.30.519
3clbTMQBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.518
3fywXCFDihydrofolate reductase1.5.1.30.518
4x5gFOLDihydrofolate reductase1.5.1.30.518
1s3uTQDDihydrofolate reductase1.5.1.30.517
3freTOPDihydrofolate reductase1.5.1.30.517
3nxvD2FDihydrofolate reductase1.5.1.30.517
4x5iFOLDihydrofolate reductase1.5.1.30.517
1og5SWFCytochrome P450 2C9/0.516
1rb3MTXDihydrofolate reductase1.5.1.30.516
3srsM23Dihydrofolate reductase1.5.1.30.515
1dr3HBIDihydrofolate reductase1.5.1.30.514
1kmsLIHDihydrofolate reductase1.5.1.30.514
3i8aN22Dihydrofolate reductase1.5.1.30.514
2drcMTXDihydrofolate reductase1.5.1.30.513
3sa27DRDihydrofolate reductase/0.513
3srqQ19Dihydrofolate reductase1.5.1.30.513
2dhfDZFDihydrofolate reductase1.5.1.30.512
3ntz3TZDihydrofolate reductase1.5.1.30.512
1drbMTXDihydrofolate reductase1.5.1.30.511
2chw039Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.511
1tdrMTXDihydrofolate reductase1.5.1.30.509
1dreMTXDihydrofolate reductase1.5.1.30.508
3antS82Bifunctional epoxide hydrolase 23.3.2.100.508
3rg9WRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.508
4eilFOLBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.507
1re7FOLDihydrofolate reductase1.5.1.30.506
3of2NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.506
4j6bPLOCytochrome P450 monooxygenase/0.506
1diuBDMDihydrofolate reductase1.5.1.30.505
1draMTXDihydrofolate reductase1.5.1.30.505
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.505
3frdDHFDihydrofolate reductase1.5.1.30.505
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.505
1mvsDTMDihydrofolate reductase1.5.1.30.504
3sqyQ11Dihydrofolate reductase1.5.1.30.504
4kd79DRDihydrofolate reductase1.5.1.30.504
3nxrD2DDihydrofolate reductase1.5.1.30.503
4ej1FOLDihydrofolate reductase1.5.1.30.503
4kne1CYDihydrofolate reductase1.5.1.30.503
1dr4HBIDihydrofolate reductase1.5.1.30.501
3tq8TOPDihydrofolate reductase/0.501
1dhjMTXDihydrofolate reductase1.5.1.30.500
1hfrMOTDihydrofolate reductase1.5.1.30.500
3ar4TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.500
4dfrMTXDihydrofolate reductase1.5.1.30.500
3dauMTXDihydrofolate reductase1.5.1.30.499
3sgv2BJDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.499
3srrQ20Dihydrofolate reductase1.5.1.30.499
4nkvAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.499
1fmjRTLRetinol dehydratase/0.498
2zbaZBATrichothecene 3-O-acetyltransferase/0.498
4r20AERCytochrome P450 family 17 polypeptide 2/0.498
3datMTXDihydrofolate reductase/0.497
3lfcZ86Mitogen-activated protein kinase 14/0.497
3nxtD2EDihydrofolate reductase1.5.1.30.497
4elb34SDihydrofolate reductase/0.497
4fhbFOLDihydrofolate reductase1.5.1.30.497
4j6dTESCytochrome P450 monooxygenase/0.497
1jolFFODihydrofolate reductase1.5.1.30.496
1ly4COQDihydrofolate reductase1.5.1.30.496
3ns2PYVAbscisic acid receptor PYL2/0.496
3s79ASDAromatase1.14.14.140.496
4elb34RDihydrofolate reductase/0.496
4jbtASDCytochrome P450 monooxygenase/0.496
4x5hFOLDihydrofolate reductase1.5.1.30.496
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.495
5hs1VORLanosterol 14-alpha demethylase/0.495
1ra2FOLDihydrofolate reductase1.5.1.30.494
2fr0NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.494
2j9lATPH(+)/Cl(-) exchange transporter 5/0.494
1ek2CDUBifunctional epoxide hydrolase 2/0.493
2fszOHTEstrogen receptor beta/0.493
3ghwGHWDihydrofolate reductase1.5.1.30.492
5cc9DDFDihydrofolate reductase1.5.1.30.492
1bzfTMQDihydrofolate reductase1.5.1.30.491
1xp9AIJEstrogen receptor/0.491
3nmpPYVAbscisic acid receptor PYL2/0.491
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.491
2w3mFOLDihydrofolate reductase1.5.1.30.490
3h3r14HCollagen type IV alpha-3-binding protein/0.490
3tdaPN0Cytochrome P450 2D6/0.490
3zkuHCVIsopenicillin N synthase1.21.3.10.490
3zoiM2WIsopenicillin N synthase1.21.3.10.490
3koo24DBifunctional epoxide hydrolase 23.3.2.100.489
3oewNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.489
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.489
1ao8MTXDihydrofolate reductase1.5.1.30.488
1dyhDZFDihydrofolate reductase1.5.1.30.488
1rx7FOLDihydrofolate reductase1.5.1.30.488
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.488
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.488
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.488
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.487
1rx8FOLDihydrofolate reductase1.5.1.30.487
1s3wTQTDihydrofolate reductase1.5.1.30.487
2qblCAMCamphor 5-monooxygenase1.14.15.10.487
4iw8KN3Estrogen receptor/0.487
1dyiFOLDihydrofolate reductase1.5.1.30.486
1oc1ASVIsopenicillin N synthase1.21.3.10.486
3kpzZNEVitamin D3 receptor/0.486
1rc4DDFDihydrofolate reductase1.5.1.30.485
3l8sBFFMitogen-activated protein kinase 14/0.485
3p9tTCLRepressor/0.485
3srwQ27Dihydrofolate reductase1.5.1.30.485
1ie9VDXVitamin D3 receptor/0.484
2c9dPHR6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.484
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.484
3qm4PN0Cytochrome P450 2D6/0.484
3qyoQ24Dihydrofolate reductase1.5.1.30.484
4i1nFOLDihydrofolate reductase1.5.1.30.484
2hw2RFPRifampin ADP-ribosyl transferase/0.483
2p15EZTEstrogen receptor/0.483
2wo7ASVIsopenicillin N synthase1.21.3.10.483
3nxyD2HDihydrofolate reductase1.5.1.30.483
1pq6965Oxysterols receptor LXR-beta/0.482
1t47NTD4-hydroxyphenylpyruvate dioxygenase1.13.11.270.482
4dquNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.482
4elg52JDihydrofolate reductase/0.482
4hw319GInduced myeloid leukemia cell differentiation protein Mcl-1/0.482
4i13FOLDihydrofolate reductase1.5.1.30.482
1rh3MTXDihydrofolate reductase1.5.1.30.481
2po7CHDFerrochelatase, mitochondrial4.99.1.10.481
3nr4PYVAbscisic acid receptor PYL2/0.481
4j26ESTEstrogen receptor beta/0.481
4lsjLSJGlucocorticoid receptor/0.481
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.481
1l2iETCEstrogen receptor/0.480
1vzdCB3Thymidylate synthase/0.480
1x8lOXRRetinol dehydratase/0.480
3gwfFADCyclohexanone monooxygenase/0.480
3tk3CPZCytochrome P450 2B41.14.14.10.480
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.480
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.479
1xddAAYIntegrin alpha-L/0.479
2fai459Estrogen receptor/0.479
2vbpVB1Isopenicillin N synthase1.21.3.10.479
3iqfE4MF420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.479
3sr5Q12Dihydrofolate reductase1.5.1.30.479
4bb3KKAIsopenicillin N synthase1.21.3.10.479
4nh82LCHeat shock protein HSP 90-alpha/0.479
1d2sDHTSex hormone-binding globulin/0.478
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.478
1ra8FOLDihydrofolate reductase1.5.1.30.478
2vcmM11Isopenicillin N synthase1.21.3.10.478
2w0bCMWLanosterol 14-alpha demethylase1.14.13.700.478
4l8u9AZSerum albumin/0.478
2m56CAMCamphor 5-monooxygenase1.14.15.10.477
2ocfESTEstrogen receptor/0.477
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.477
2y98MIVMycinamicin IV hydroxylase/epoxidase/0.477
3cv9VDXVitamin D3 dihydroxylase/0.477
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.477
4m7vRARDihydrofolate reductase/0.477
4ubsDIFPentalenic acid synthase1.14.15.110.477
1rx5DDFDihydrofolate reductase1.5.1.30.476
3ezpB3NHistone deacetylase 83.5.1.980.476
2y46MIVMycinamicin IV hydroxylase/epoxidase/0.475
3lnbCOAN-acetyltransferase family protein/0.475
4a81DXCMajor pollen allergen Bet v 1-A/0.475
4bb6HD1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.475
4ele31IDihydrofolate reductase/0.475
4hni16WCasein kinase I isoform epsilon2.7.11.10.475
4ia7BIVVitamin D3 receptor A/0.475
4iui1GQEstrogen receptor/0.475
3p99LNPLanosterol 14-alpha-demethylase/0.474
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.474
1rx2FOLDihydrofolate reductase1.5.1.30.473
2jn3JN3Fatty acid-binding protein, liver/0.473
3a4pDFQHepatocyte growth factor receptor2.7.10.10.473
3iqzH4MF420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.473
4bfrJ82Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform2.7.1.1530.473
4ia1BIVVitamin D3 receptor A/0.473
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.473
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.472
2q9fC3SCholesterol 24-hydroxylase/0.472
2x7hPFNProstaglandin reductase 310.472
3d84NDPDihydrofolate reductase1.5.1.30.472
3gyf51PDihydrofolate reductase1.5.1.30.472
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.472
3l0lHC3Nuclear receptor ROR-gamma/0.472
1rx6DDFDihydrofolate reductase1.5.1.30.471
1ysx4EBSerum albumin/0.471
1zidZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.471
2bj4OHTEstrogen receptor/0.471
2qk8MTXDihydrofolate reductase/0.471
3ar5TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.471
3fwiCAMCamphor 5-monooxygenase1.14.15.10.471
3gmd2M3Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.471
3h3t16HCollagen type IV alpha-3-binding protein/0.471
3sruQ26Dihydrofolate reductase1.5.1.30.471
4awo99BHeat shock protein HSP 90-alpha/0.471
1ml6GBXGlutathione S-transferase A22.5.1.180.470
2jedLG8Protein kinase C theta type2.7.11.130.470
2vn0TDZCytochrome P450 2C8/0.470
3cr7PPSAdenylyl-sulfate kinase2.7.1.250.470
3vrwYS5Vitamin D3 receptor/0.470
3wrhCAMCamphor 5-monooxygenase1.14.15.10.470
4e0u0MVCyclic dipeptide N-prenyltransferase/0.470
1rd7FOLDihydrofolate reductase1.5.1.30.469
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.469
1tbbROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.469
2g44T3OEstrogen receptor/0.469
2w9gTOPDihydrofolate reductase1.5.1.30.469
2y30SM8Putative repressor SimReg2/0.469
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.469
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.469
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.469
3iakEV1cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.469
3mg3ECHOrange carotenoid-binding protein/0.469
3ollESTEstrogen receptor beta/0.469
3pre3REPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.469
4m6kFOLDihydrofolate reductase1.5.1.30.469
5hi6MTXDihydrofolate reductase/0.469
1krv147Galactoside O-acetyltransferase2.3.1.180.468
1s19MC9Vitamin D3 receptor/0.468
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.468
1yqj6NPMitogen-activated protein kinase 14/0.468
2fwzH71Heat shock protein HSP 90-alpha/0.468
2jb4A14Isopenicillin N synthase1.21.3.10.468
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.468
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.468
3h3sH15Collagen type IV alpha-3-binding protein/0.468
3w9rA8SAbscisic acid receptor PYL9/0.468
4dtiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.468
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.468
4p6wMOFGlucocorticoid receptor/0.468
1qknRALEstrogen receptor beta/0.467
1s4dSAHUroporphyrinogen-III C-methyltransferase2.1.1.1070.467
2b1z17MEstrogen receptor/0.467
2jf9OHTEstrogen receptor/0.467
3fwgCAMCamphor 5-monooxygenase1.14.15.10.467
3gc9B45Mitogen-activated protein kinase 112.7.11.240.467
3gieACPSensor histidine kinase DesK2.7.13.30.467
3p3zP3ZPutative cytochrome P450/0.467
4rraA3TProbable threonine--tRNA ligase 26.1.1.30.467
4v12POGMaoC like domain protein/0.467
5bp9SAHPutative methyltransferase protein/0.467
5d7q4I5NAD-dependent protein deacetylase sirtuin-23.5.10.467
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
1jraFADFAD-linked sulfhydryl oxidase ERV21.8.3.20.466
1rf7DHFDihydrofolate reductase1.5.1.30.466
1s7gNADNAD-dependent protein deacylase 2/0.466
1uhlMEIRetinoic acid receptor RXR-beta/0.466
1zky689Estrogen receptor/0.466
2npnSAMPutative cobalamin synthesis related protein/0.466
2wsa646Glycylpeptide N-tetradecanoyltransferase/0.466
3fy8XCFDihydrofolate reductase1.5.1.30.466
3negPYVAbscisic acid receptor PYL1/0.466
3q95ESLEstrogen receptor/0.466
4lhtCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.466
4qa1B3NHistone deacetylase 83.5.1.980.466
4rrmA3TProbable threonine--tRNA ligase 26.1.1.30.466
4xoqF42Coenzyme F420:L-glutamate ligase/0.466
1b2lNDCAlcohol dehydrogenase1.1.1.10.465
1f5fDHTSex hormone-binding globulin/0.465
1iwjCAMCamphor 5-monooxygenase1.14.15.10.465
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.465
2b36NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.465
2hasC3OVitamin D3 receptor/0.465
2y6fM9FIsopenicillin N synthase1.21.3.10.465
3fyvXCFDihydrofolate reductase1.5.1.30.465
3oq13OQCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.465
1blzACVIsopenicillin N synthase1.21.3.10.464
1c1bGCAGag-Pol polyprotein2.7.7.490.464
1db1VDXVitamin D3 receptor/0.464
1disBDMDihydrofolate reductase1.5.1.30.464
1fmlRTLRetinol dehydratase/0.464
1ra3MTXDihydrofolate reductase1.5.1.30.464
1s3vTQDDihydrofolate reductase1.5.1.30.464
1tw4CHDFatty acid-binding protein, liver/0.464
2feuCAMCamphor 5-monooxygenase1.14.15.10.464
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.464
2jfaRALEstrogen receptor/0.464
2oaxSNLMineralocorticoid receptor/0.464
2ph5NADHomospermidine synthase/0.464
2qboCAMCamphor 5-monooxygenase1.14.15.10.464
2uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.464
2w9hTOPDihydrofolate reductase1.5.1.30.464
3kb0A8SAbscisic acid receptor PYL2/0.464
3mdvCL6Cholesterol 24-hydroxylase/0.464
4dreNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.464
4jlj1NMDeoxycytidine kinase2.7.1.740.464
4o701QKBromodomain-containing protein 4/0.464
3pwhZMAAdenosine receptor A2a/0.464
1e6eFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.463
1kmvLIIDihydrofolate reductase1.5.1.30.463
1nzyBCA4-chlorobenzoyl coenzyme A dehalogenase3.8.1.70.463
1psdNADD-3-phosphoglycerate dehydrogenase1.1.1.950.463
1txiTX5Vitamin D3 receptor/0.463
1uzwCDHIsopenicillin N synthase1.21.3.10.463
1xpcAITEstrogen receptor/0.463
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.463
2c94TSF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.463
2hamC33Vitamin D3 receptor/0.463
2hb8MVDVitamin D3 receptor/0.463
3c1tMYCDihydroflavonol 4-reductase1.1.1.2190.463
3lakKR1Gag-Pol polyprotein2.7.7.490.463
3njoPYVAbscisic acid receptor PYR1/0.463
4fw05KJNitric oxide synthase, brain1.14.13.390.463
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.463
1ezfIN0Squalene synthase2.5.1.210.462
1hb3SCVIsopenicillin N synthase1.21.3.10.462
1p44NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.462
1rd4L08Integrin alpha-L/0.462
2apgFADFlavin-dependent tryptophan halogenase PrnA1.14.19.90.462
2d0kFOLDihydrofolate reductase1.5.1.30.462
2hb7O1CVitamin D3 receptor/0.462
2ntjP1HEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.462
2rhrEMOPutative ketoacyl reductase1.3.10.462
2uxoTACHTH-type transcriptional regulator TtgR/0.462
2z97CAMCamphor 5-monooxygenase1.14.15.10.462
3abaFLICytochrome P450/0.462
3ebf332Nitric oxide synthase, inducible1.14.13.390.462
4dsbA8SAbscisic acid receptor PYL3/0.462
1enzNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.461
1jomFFODihydrofolate reductase1.5.1.30.461
1m13HYFNuclear receptor subfamily 1 group I member 2/0.461
2aqkNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.461
2nnhREACytochrome P450 2C8/0.461
2zlcVDXVitamin D3 receptor/0.461
3a8wATPProtein kinase C iota type2.7.11.130.461
3wsbRWZFarnesyltransferase, putative/0.461
3zsh469Mitogen-activated protein kinase 14/0.461
4hy6FJ1Heat shock protein HSP 90-alpha/0.461
4u0oMTALipoyl synthase 2/0.461
5gcnCOAHAT A1/0.461
1mvtDTMDihydrofolate reductase1.5.1.30.460
1qjfACSIsopenicillin N synthase1.21.3.10.460
2uxhQUEHTH-type transcriptional regulator TtgR/0.460
2ze2T27Gag-Pol polyprotein2.7.7.490.460
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.460
3iqeF42F420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.460
3tqaNDPDihydrofolate reductase/0.460
3w0gW07Vitamin D3 receptor/0.460
4aosNAPSteroid monooxygenase/0.460
4c3yANB3-ketosteroid dehydrogenase/0.460
4g1z0VPVitamin D3 receptor A/0.460
4g210VPVitamin D3 receptor A/0.460
4i6f1C7Serine/threonine-protein kinase PLK22.7.11.210.460
4k9yK9YFocal adhesion kinase 12.7.10.20.460
4l9kEHFSerum albumin/0.460
4lxjLANLanosterol 14-alpha demethylase1.14.13.700.460
4rbs0RVMetallo-beta-lactamase type 2/0.460
4rujVDXVitamin D3 receptor A/0.460
1enyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.459
1f20FADNitric oxide synthase, brain1.14.13.390.459
1gwrESTEstrogen receptor/0.459
1obnASVIsopenicillin N synthase1.21.3.10.459
2g5oDRQEstrogen receptor/0.459
2l98STLTroponin C, slow skeletal and cardiac muscles/0.459
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.459
2q70DC8Estrogen receptor/0.459
2wi72KLHeat shock protein HSP 90-alpha/0.459
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.459
3nglNAPBifunctional protein FolD/0.459
3w5eNVWcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.459
3zbnCOA3-ketoacyl-CoA thiolase-like protein/0.459
4j24ESTEstrogen receptor beta/0.459
4jf1PLPAcetylornithine/succinyldiaminopimelate aminotransferase2.6.1.110.459
4lb2DM5Serum albumin/0.459
4nieNBHNuclear receptor ROR-gamma/0.459
4ruoBIVVitamin D3 receptor A/0.459
6cp4CAMCamphor 5-monooxygenase1.14.15.10.459
3uzaT4GAdenosine receptor A2a/0.459
1rk3VDXVitamin D3 receptor/0.458
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.458
1xu7CPSCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.458
2hcdBIVVitamin D3 receptor A/0.458
3a783EVVitamin D3 receptor/0.458
3zkyWT4Isopenicillin N synthase1.21.3.10.458
3zu2NAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.458
4bmpFMNProtein NrdI/0.458
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.458
4iteTEYVitamin D3 receptor/0.458
4qjcIXEDihydrofolate reductase1.5.1.30.458
4uyf73BBromodomain-containing protein 2/0.458
1pkfEPDEpothilone C/D epoxidase1.140.457
1qiqACCIsopenicillin N synthase1.21.3.10.457
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.457
1t88CAMCamphor 5-monooxygenase1.14.15.10.457
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.10.457
1yimCM4Estrogen receptor/0.457
2e98B29Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.457
2nv6ZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.457
2qbmCAMCamphor 5-monooxygenase1.14.15.10.457
2qe4JJ3Estrogen receptor/0.457
3c3dFO12-phospho-L-lactate transferase/0.457
3fl8RARDihydrofolate reductase/0.457
4enhFVXCholesterol 24-hydroxylase/0.457
4g1y0VOVitamin D3 receptor A/0.457
4ivy1GTEstrogen receptor/0.457
4jvnYUGEstrogen sulfotransferase2.8.2.40.457
4lgaA2OAbscisic acid receptor PYL2/0.457
4ugaQ05Nitric oxide synthase oxygenase1.14.13.1650.457
5k2cZMAAdenosine receptor A2a/0.457
1dz4CAMCamphor 5-monooxygenase1.14.15.10.456
1dz6CAMCamphor 5-monooxygenase1.14.15.10.456
1hb1OCVIsopenicillin N synthase1.21.3.10.456
1nhz486Glucocorticoid receptor/0.456
1pd8CO4Dihydrofolate reductase1.5.1.30.456
1rx4DDFDihydrofolate reductase1.5.1.30.456
1upw444Oxysterols receptor LXR-beta/0.456
2cchATPCyclin-dependent kinase 22.7.11.220.456
2vkeTACTetracycline repressor protein class D/0.456
2wkmPFYHepatocyte growth factor receptor2.7.10.10.456
3fwfCAMCamphor 5-monooxygenase1.14.15.10.456
3fy9XCFDihydrofolate reductase1.5.1.30.456
3ibdCPZCytochrome P450 2B61.14.130.456
3irxUDRGag-Pol polyprotein2.7.7.490.456
3k4551PDihydrofolate reductase1.5.1.30.456
3uvvREARetinoic acid receptor RXR-alpha/0.456
3wrlCAMCamphor 5-monooxygenase1.14.15.10.456
4fex0TOAminoglycoside 3'-phosphotransferase AphA1-IAB/0.456
4gg70J8Hepatocyte growth factor receptor2.7.10.10.456
4rrhA3SProbable threonine--tRNA ligase 26.1.1.30.456
1lhwESMSex hormone-binding globulin/0.455
1o6rR19Squalene--hopene cyclase4.2.1.1290.455
1uy8PU5Heat shock protein HSP 90-alpha/0.455
1x7e244Estrogen receptor/0.455
2giuFBREstrogen receptor beta/0.455
2nq8ZIDEnoyl-ACP reductase/0.455
2rqfJH3Hemolymph juvenile hormone binding protein/0.455
2yhdTESAndrogen receptor/0.455
2zl9VDAVitamin D3 receptor/0.455
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.455
3l6jZ90Alr2278 protein/0.455
3ojiPYVAbscisic acid receptor PYL3/0.455
3tmz06XCytochrome P450 2B41.14.14.10.455
3vt65YIVitamin D3 receptor/0.455
4a7cE46Serine/threonine-protein kinase pim-12.7.11.10.455
4ajwVWNPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform2.7.1.1530.455
4bqpNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.455
4g20484Vitamin D3 receptor A/0.455
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
4tuvCPZCytochrome P450 1191.140.455
5cp4CAMCamphor 5-monooxygenase1.14.15.10.455
1kl2FONSerine hydroxymethyltransferase/0.454
1uwhBAXSerine/threonine-protein kinase B-raf2.7.11.10.454
1vrwNAIEnoyl-ACP reductase/0.454
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.454
2b378PSEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.454
2idzZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.454
3sls77DDual specificity mitogen-activated protein kinase kinase 12.7.12.20.454
3w0jT08Vitamin D3 receptor/0.454
4jr51LSNicotinamide phosphoribosyltransferase2.4.2.120.454
4o1mNADEnoyl-acyl carrier reductase/0.454
5dx3ESTEstrogen receptor/0.454
1n4hREANuclear receptor ROR-beta/0.453
1nq7ARLNuclear receptor ROR-beta/0.453
1tl7FOKAdenylate cyclase type 2/0.453
1tl7FOKAdenylate cyclase type 5/0.453
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.453
2ij7TPFMycocyclosin synthase1.14.21.90.453
2j7yE3OEstrogen receptor beta/0.453
2nn7M29Carbonic anhydrase 14.2.1.10.453
2q66ATPPoly(A) polymerase2.7.7.190.453
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.453
3c3xNAPEugenol synthase 11.1.1.3180.453
3fkoFKOMitogen-activated protein kinase 14/0.453
3jpuTY4Transcriptional activator protein LasR/0.453
3w0hW12Vitamin D3 receptor/0.453
4cdmFO1Deoxyribodipyrimidine photolyase/0.453
4cp4CAMCamphor 5-monooxygenase1.14.15.10.453
4dvq1CACytochrome P450 11B2, mitochondrial1.14.15.40.453
4fewPP2Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.453
4gyzD5MTyrosyl-DNA phosphodiesterase 23.1.40.453
1uy7PU4Heat shock protein HSP 90-alpha/0.452
1vrqFONSubunit alpha of sarocosine oxidase/0.452
1w06W05Isopenicillin N synthase1.21.3.10.452
1w1rZEACytokinin dehydrogenase 11.5.99.120.452
1yrdCAMCamphor 5-monooxygenase1.14.15.10.452
1yreCOAUncharacterized protein/0.452
2dqsTG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.452
2yjxYJXHeat shock protein HSP 90-alpha/0.452
2ykeYKEHeat shock protein HSP 90-alpha/0.452
2zcePYLPyrrolysine--tRNA ligase/0.452
3a1l2CCCytochrome P450/0.452
3h1jSMACytochrome b/0.452
3iw8HIZMitogen-activated protein kinase 14/0.452
3kp4MIITranscriptional regulator TcaR/0.452
3qlhT27Gag-Pol polyprotein2.7.7.490.452
3tdl11DSerum albumin/0.452
3uudESTEstrogen receptor/0.452
3vt5YI2Vitamin D3 receptor/0.452
3vtcTK3Vitamin D3 receptor/0.452
4ap1NAPSteroid monooxygenase/0.452
4bb5HD2Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.452
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.452
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
1bk0ACVIsopenicillin N synthase1.21.3.10.451
1pd9CO4Dihydrofolate reductase1.5.1.30.451
1u2gAPRNAD(P) transhydrogenase subunit alpha part 11.6.1.20.451
1vceSAHDiphthine synthase/0.451
2cleF6FTryptophan synthase alpha chain/0.451
3csdEMOPutative ketoacyl reductase1.3.10.451
3e6oA55Nitric oxide synthase, inducible1.14.13.390.451
3flzFLZMitogen-activated protein kinase 14/0.451
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.451
3gcq1BUMitogen-activated protein kinase 14/0.451
3hz142CHeat shock protein HSP 90-alpha/0.451
3l034OHEstrogen receptor/0.451
3lkhLT6Genome polyprotein2.7.7.480.451
3nxxNDPDihydrofolate reductase1.5.1.30.451
4g1qT27Gag-Pol polyprotein2.7.7.490.451
4i8vBHFCytochrome P450 1A11.14.14.10.451
5bt42LOBromodomain-containing protein 4/0.451
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
5dxgESTEstrogen receptor/0.451
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.450
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.450
1jioDEB6-deoxyerythronolide B hydroxylase/0.450
1ludTRRDihydrofolate reductase1.5.1.30.450
1rkhVD2Vitamin D3 receptor/0.450
2bxoOPBSerum albumin/0.450
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
2harOCCVitamin D3 receptor/0.450
2hc4VDXVitamin D3 receptor A/0.450
2hrcCHDFerrochelatase, mitochondrial4.99.1.10.450
2o4jVD4Vitamin D3 receptor/0.450
2p7zOHTEstrogen-related receptor gamma/0.450
2v58LZJBiotin carboxylase6.3.4.140.450
2vn1FK5Peptidylprolyl isomerase/0.450
2xtbKRMAdenosine kinase, putative/0.450
3b3pJI7Nitric oxide synthase, brain1.14.13.390.450
3erdDESEstrogen receptor/0.450
3gggNADPrephenate dehydrogenase/0.450
3s7a684Dihydrofolate reductase1.5.1.30.450
3t3q9PLCytochrome P450 2A61.14.130.450
4at2ASDPossible succinate dehydrogenase/0.450
4bcqTJFCyclin-dependent kinase 22.7.11.220.450
4dscA8SAbscisic acid receptor PYL3/0.450
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.450
4iv21GREstrogen receptor/0.450
4qa2SHHHistone deacetylase 83.5.1.980.450
4ug71EVNitric oxide synthase oxygenase1.14.13.1650.450
4zasTYDCalS13/0.450
1cs4FOKAdenylate cyclase type 2/0.449
1cs4FOKAdenylate cyclase type 5/0.449
1eioGCHGastrotropin/0.449
1kijNOVDNA gyrase subunit B/0.449
1q20PLOSulfotransferase family cytosolic 2B member 12.8.2.20.449
1rjkVDZVitamin D3 receptor/0.449
1t87CAMCamphor 5-monooxygenase1.14.15.10.449
1xdsDRAAclacinomycin 10-hydroxylase RdmB4.1.10.449
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.449
2cppCAMCamphor 5-monooxygenase1.14.15.10.449
2iviACWIsopenicillin N synthase1.21.3.10.449
2rkvZBATrichothecene 3-O-acetyltransferase/0.449
3dgeADPSensor histidine kinase/0.449
3fwjCAMCamphor 5-monooxygenase1.14.15.10.449
3gobHXXDdmC/0.449
3k4s0MOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.449
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.449
3qj5022Alcohol dehydrogenase class-31.1.1.10.449
3u8hBHPPhospholipase A2, membrane associated/0.449
3uf7ASP_ILE_PRO_PHEUracil-DNA glycosylase3.2.2.270.449
3vhuSNLMineralocorticoid receptor/0.449
3vrtYS2Vitamin D3 receptor/0.449
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4cztCPSCBL-interacting serine/threonine-protein kinase 232.7.11.10.449
4hnc0UTMandelate racemase/0.449
4jq7KJQEpidermal growth factor receptor2.7.10.10.449
4m6p20RNicotinamide phosphoribosyltransferase2.4.2.120.449
1bwsNDPGDP-L-fucose synthase/0.448
1cjtFOKAdenylate cyclase type 2/0.448
1cjtFOKAdenylate cyclase type 5/0.448
1cqp803Integrin alpha-L/0.448
1g50ESTEstrogen receptor/0.448
1jpaANPEphrin type-B receptor 22.7.10.10.448
1kt6RTLRetinol-binding protein 4/0.448
1p6jDP9Nitric oxide synthase, brain1.14.13.390.448
1rg7MTXDihydrofolate reductase1.5.1.30.448
1yinCM3Estrogen receptor/0.448
2yekEAMBromodomain-containing protein 2/0.448
2yx6ADPUncharacterized protein/0.448
3nefPYVAbscisic acid receptor PYL1/0.448
3nksACJProtoporphyrinogen oxidase1.3.3.40.448
3pm0BHFCytochrome P450 1B1/0.448
3sn7540cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.448
3zk5Z18Cytochrome P450 monooxygenase PikC/0.448
4fhi0S4Vitamin D3 receptor A/0.448
4mv4ACPBiotin carboxylase6.3.4.140.448
4rupH97Vitamin D3 receptor A/0.448
4xcvNDPProbable hydroxyacid dehydrogenase protein/0.448
5h8tRTLRetinol-binding protein 1/0.448
5iua6DXAdenosine receptor A2a/0.448
1crbRTLRetinol-binding protein 1/0.447
1e1nFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.447
1ove358Mitogen-activated protein kinase 14/0.447
1p44GEQEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
1tvrTB9Gag-Pol polyprotein2.7.7.490.447
1uyuCAMCamphor 5-monooxygenase1.14.15.10.447
2bbqPFGThymidylate synthase/0.447
2bu9HFVIsopenicillin N synthase1.21.3.10.447
2iw84SPCyclin-dependent kinase 22.7.11.220.447
2q7gCCLPyrrolysine--tRNA ligase/0.447
2qbnCAMCamphor 5-monooxygenase1.14.15.10.447
2vteIK4UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.447
2w6oOA3Biotin carboxylase6.3.4.140.447
3aosJH2Hemolymph juvenile hormone binding protein/0.447
3c14FOKAdenylate cyclase type 2/0.447
3c14FOKAdenylate cyclase type 5/0.447
3ch6311Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.447
3dhaC6LN-acyl homoserine lactonase AiiA3.1.1.810.447
3g5hYTTMycocyclosin synthase1.14.21.90.447
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
3ov4EQUSteroid Delta-isomerase5.3.3.10.447
3p6pA6BCamphor 5-monooxygenase1.14.15.10.447
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
3wv9FEGHmd co-occurring protein HcgE/0.447
3zv5BPYCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase1.3.1.560.447
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.447
4gki0JNAminoglycoside 3'-phosphotransferase AphA1-IAB/0.447
4ipw1G7Mycocyclosin synthase1.14.21.90.447
4jlk1NODeoxycytidine kinase2.7.1.740.447
4klaCHDFerrochelatase, mitochondrial4.99.1.10.447
4lt63ATPoly(A) polymerase gamma2.7.7.190.447
4rr7A3SProbable threonine--tRNA ligase 26.1.1.30.447
1gwqZTWEstrogen receptor/0.446
1i58ACPChemotaxis protein CheA2.7.13.30.446
1jtqLY3Thymidylate synthase/0.446
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.446
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.446
1rdtL79Retinoic acid receptor RXR-alpha/0.446
1rkgVD1Vitamin D3 receptor/0.446
1sr7MOFProgesterone receptor/0.446
2cdcNAPGlucose 1-dehydrogenase/0.446
2ejzSAHDiphthine synthase/0.446
2h42VIAcGMP-specific 3',5'-cyclic phosphodiesterase/0.446
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.446
3fnlSHALactoperoxidase/0.446
3gwfNAPCyclohexanone monooxygenase/0.446
3invNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.446
3l63CAMCamphor 5-monooxygenase1.14.15.10.446
3mnrSD1Heat shock protein HSP 90-alpha/0.446
3rukAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.446
3sl2ATPSensor histidine kinase WalK/0.446
3v94WYQPhosphodiesterase/0.446
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4gkh0J9Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.446
4iv41GSEstrogen receptor/0.446
4l6gCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.446
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.446
4v2gITCTetracycline repressor protein class D/0.446
5akk1P8Bifunctional epoxide hydrolase 23.1.3.760.446
5d1bTSNHistone deacetylase 83.5.1.980.446
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.446
3rfmCFFAdenosine receptor A2a/0.446
1ay0TPPTransketolase 12.2.1.10.445
1dtpAPUDiphtheria toxin/0.445
1dz8CAMCamphor 5-monooxygenase1.14.15.10.445
1enpNADEnoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic1.3.1.90.445
1fm4DXCMajor pollen allergen Bet v 1-L/0.445
1jutLYDThymidylate synthase/0.445
1r35I58Nitric oxide synthase, inducible1.14.13.390.445
1rb2FOLDihydrofolate reductase1.5.1.30.445
1tl1H18Gag-Pol polyprotein2.7.7.490.445
1ykdCMPAdenylate cyclase/0.445
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.445
2iogIOGEstrogen receptor/0.445
2qd3CHDFerrochelatase, mitochondrial4.99.1.10.445
2vx07X7Ephrin type-B receptor 42.7.10.10.445
2y37A54Nitric oxide synthase, inducible1.14.13.390.445
2zd1T27Gag-Pol polyprotein2.7.7.490.445
3ar7TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.445
3gd3FADApoptosis-inducing factor 1, mitochondrial1.1.10.445
3t8xT8XT-cell surface glycoprotein CD1b/0.445
3tm5SFGUncharacterized protein/0.445
3w0iO11Vitamin D3 receptor/0.445
3w5rLOAVitamin D3 receptor/0.445
4elh53IDihydrofolate reductase/0.445
4j6i1JVPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4lwaQ13Nitric oxide synthase oxygenase1.14.13.1650.445
4mv3ACPBiotin carboxylase6.3.4.140.445
4o761M3Bromodomain-containing protein 4/0.445
1bvrTHTEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
1dhiMTXDihydrofolate reductase1.5.1.30.444
1fm99CRRetinoic acid receptor RXR-alpha/0.444
1ie8KH1Vitamin D3 receptor/0.444
1l2jETCEstrogen receptor beta/0.444
1m9m6NINitric oxide synthase, endothelial1.14.13.390.444
1sbrVIBPutative HMP/thiamine-binding protein YkoF/0.444
1uyfPU1Heat shock protein HSP 90-alpha/0.444
1xj7DHTAndrogen receptor/0.444
1xp1AIHEstrogen receptor/0.444
1yhoTRRDihydrofolate reductase1.5.1.30.444
2a1nCAMCamphor 5-monooxygenase1.14.15.10.444
2aclREARetinoic acid receptor RXR-alpha/0.444
2ehlSAHDiphthine synthase/0.444
2jc6QPPCalcium/calmodulin-dependent protein kinase type 1D2.7.11.170.444
2qgtEEDEstrogen receptor/0.444
2uxuNARHTH-type transcriptional regulator TtgR/0.444
2vrbNAPTriphenylmethane reductase/0.444
2y60M8FIsopenicillin N synthase1.21.3.10.444
3b99U51Prostacyclin synthase/0.444
3blrCPBCyclin-dependent kinase 92.7.11.220.444
3h0a9RARetinoic acid receptor RXR-alpha/0.444
3itzP66Mitogen-activated protein kinase 14/0.444
3jyqNADQuinate/shikimate dehydrogenase (NAD(+))/0.444
3new3NEMitogen-activated protein kinase 14/0.444
3oeyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
3vrvYSDVitamin D3 receptor/0.444
3vtdTKDVitamin D3 receptor/0.444
3w0aDS5Vitamin D3 receptor/0.444
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.444
3wrjCAMCamphor 5-monooxygenase1.14.15.10.444
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4g1d0VKVitamin D3 receptor A/0.444
4h6rFDAProline dehydrogenase/0.444
4jvmXDIEstrogen sulfotransferase2.8.2.40.444
4l4aCAMCamphor 5-monooxygenase1.14.15.10.444
3emlZMAAdenosine receptor A2a/0.444
1al8DHPPeroxisomal (S)-2-hydroxy-acid oxidase1.1.3.150.443
1m8h6NINitric oxide synthase, inducible1.14.13.390.443
1o76CAMCamphor 5-monooxygenase1.14.15.10.443
1ot7CHCBile acid receptor/0.443
1q5dEPBEpothilone C/D epoxidase1.140.443
1sqbAZOCytochrome b/0.443
1t85CAMCamphor 5-monooxygenase1.14.15.10.443
1u71MXADihydrofolate reductase1.5.1.30.443
2aqiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
2bxmIMNSerum albumin/0.443
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.443
2ovvPFHcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
2puiADPMethylthioribose kinase2.7.1.1000.443
2pulACPMethylthioribose kinase2.7.1.1000.443
2qo4CHDFatty acid-binding protein 10-A, liver basic/0.443
3clbNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.443
3e7tB14Nitric oxide synthase, inducible1.14.13.390.443
3gb4D3MDdmC/0.443
3h6k33TCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.443
3ziaADPATP synthase subunit beta, mitochondrial3.6.3.140.443
3zqtTESAndrogen receptor/0.443
4a83DXCMajor pollen allergen Bet v 1-A/0.443
4d7eFADPutative lysine-N-oxygenase/0.443
4dma0L8Estrogen receptor/0.443
4dpy2P0Mevalonate diphosphate decarboxylase/0.443
4ek1CAMCamphor 5-monooxygenase1.14.15.10.443
4equG6ISerine/threonine-protein kinase 102.7.11.10.443
4hfr14MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.443
4iah1DXAlr2278 protein/0.443
4iw61GUEstrogen receptor/0.443
4jnc1LFBifunctional epoxide hydrolase 23.1.3.760.443
4yaf2AMNADPH--cytochrome P450 reductase/0.443
1ahiCHO7-alpha-hydroxysteroid dehydrogenase1.1.1.1590.442
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
1phgMYTCamphor 5-monooxygenase1.14.15.10.442
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.442
1xu9CPSCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.442
2bakAQZMitogen-activated protein kinase 14/0.442
2fpcSCGStrictosidine synthase4.3.3.20.442
2ykbYKBHeat shock protein HSP 90-alpha/0.442
3cppCAMCamphor 5-monooxygenase1.14.15.10.442
3d3eD3ECorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.442
3drcMTXDihydrofolate reductase1.5.1.30.442
3eej53RUncharacterized protein/0.442
3ey9TDPPyruvate dehydrogenase [ubiquinone]1.2.5.10.442
3ft8MOJHeat shock protein HSP 90-alpha/0.442
3gkjHC3Niemann-Pick C1 protein/0.442
3kdiA8SAbscisic acid receptor PYL2/0.442
3qdd94MHeat shock protein HSP 90-alpha/0.442
4a9mP9MBromodomain-containing protein 2/0.442
4a9yAQZMitogen-activated protein kinase 14/0.442
4b5bBBEGlucose-1-phosphate thymidylyltransferase/0.442
4c9oCAMCytochrome P450/0.442
4g2fC07Ephrin type-A receptor 32.7.10.10.442
4ogrADNCyclin-dependent kinase 92.7.11.220.442
4wa9AXITyrosine-protein kinase ABL12.7.10.20.442
5eccNAPDehydrofolate reductase type I/0.442
5hyrESTEstrogen receptor/0.442
1dr3TAPDihydrofolate reductase1.5.1.30.441
1k749CRRetinoic acid receptor RXR-alpha/0.441
1o5rFR9Adenosine deaminase3.5.4.40.441
1ohkCOPDihydrofolate reductase1.5.1.30.441
1rf9DBRCamphor 5-monooxygenase1.14.15.10.441
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.441
1xoqROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.441
2azzTCHPhospholipase A2, major isoenzyme3.1.1.40.441
2hm9TRRDihydrofolate reductase1.5.1.30.441
2itqITQEpidermal growth factor receptor2.7.10.10.441
2ntvP1HEnoyl-[acyl-carrier-protein] reductase [NADH]/0.441
2ovhAS0Progesterone receptor/0.441
2rtmIMIStreptavidin/0.441
2yejXQKHeat shock protein HSP 90-alpha/0.441
2ylpTESAndrogen receptor/0.441
3bgrT27Gag-Pol polyprotein2.7.7.490.441
3cquCQURAC-alpha serine/threonine-protein kinase2.7.11.10.441
3f63GTXGlutathione transferase GST1-4/0.441
3hcrCHDFerrochelatase, mitochondrial4.99.1.10.441
3hz5Z64Heat shock protein HSP 90-alpha/0.441
3lu8IQXSerum albumin/0.441
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.441
3p6oETGCamphor 5-monooxygenase1.14.15.10.441
4e5yNDPGDP-L-fucose synthase1.1.1.2710.441
4gh30EVQueuine tRNA-ribosyltransferase2.4.2.290.441
4ktl1CQCytochrome P450/0.441
4qemHC4Phospholipase A2 VRV-PL-VIIIa/0.441
5iu4ZMAAdenosine receptor A2a/0.441
5k2aZMAAdenosine receptor A2a/0.441
3reyXACAdenosine receptor A2a/0.441
1cjcFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.440
1kdmDHTSex hormone-binding globulin/0.440
1pl8NADSorbitol dehydrogenase1.1.1.140.440
1q9mROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.440
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.440
1wrlTFPTroponin C, slow skeletal and cardiac muscles/0.440
1x7rGENEstrogen receptor/0.440
1zg32HIIsoflavone 4'-O-methyltransferase/0.440
2bxqIMNSerum albumin/0.440
2cdaNAPGlucose 1-dehydrogenase/0.440
2eh5SAHDiphthine synthase/0.440
2j9gANPBiotin carboxylase6.3.4.140.440
2ouzC3DEstrogen receptor/0.440
2pnjCHDFerrochelatase, mitochondrial4.99.1.10.440
3bqdDAYGlucocorticoid receptor/0.440
3d75NBBPheromone-binding protein ASP1/0.440
3f03FMNPentaerythritol tetranitrate reductase/0.440
3njoP2MAbscisic acid receptor PYR1/0.440
3owsEQUSteroid Delta-isomerase5.3.3.10.440
3pqbVGPPutative oxidoreductase/0.440
3up0D7SaceDAF-12/0.440
3v4eCOAPutative acetyltransferase SACOL25702.3.10.440
3vt7VDXVitamin D3 receptor/0.440
3w0yDS4Vitamin D3 receptor/0.440
3zrbOR8Progesterone receptor/0.440
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
4c9pCAMCytochrome P450/0.440
4eftEFTHeat shock protein HSP 90-alpha/0.440
4ejgNCTCytochrome P450 2A131.14.14.10.440
4fad0TBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4feu537Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.440
4gxs0YSGlutamate receptor 2/0.440
4ia3BIVVitamin D3 receptor A/0.440
4ib4ERM5-hydroxytryptamine receptor 2B/0.440
4lg5A1OAbscisic acid receptor PYL2/0.440
4lvb20NNicotinamide phosphoribosyltransferase2.4.2.120.440