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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3u4cNDPNADPH-dependent reductase BacG

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3u4cNDPNADPH-dependent reductase BacG/1.000
1x7gNAPPutative ketoacyl reductase1.3.10.475
4dc1NDPPutative ketoacyl reductase1.3.10.461
3qrwNDPPutative ketoacyl reductase1.3.10.459
1ae1NAPTropinone reductase 1/0.454
4hwkNAPSepiapterin reductase1.1.1.1530.453
4qedNAPElxO/0.451
1ipeNDPTropinone reductase 21.1.1.2360.449
4qecNAPElxO/0.447
3toxNAPPutative oxidoreductase/0.446
3uceNDPDehydrogenase/0.446
1w4zNAPPutative ketoacyl reductase1.3.10.443
1x7hNDPPutative ketoacyl reductase1.3.10.443
4bmvNAPShort-chain dehydrogenase/0.443
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.442
2yutNAPPutative short-chain oxidoreductase/0.441