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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3ttjJBIMitogen-activated protein kinase 102.7.11.24

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3ttjJBIMitogen-activated protein kinase 102.7.11.241.000
1pmn984Mitogen-activated protein kinase 102.7.11.240.739
2p33J07Mitogen-activated protein kinase 102.7.11.240.646
2excJNKMitogen-activated protein kinase 102.7.11.240.623
3ttiKBIMitogen-activated protein kinase 102.7.11.240.617
2o0uC0MMitogen-activated protein kinase 102.7.11.240.604
2b1pAIZMitogen-activated protein kinase 102.7.11.240.598
3cgfJNFMitogen-activated protein kinase 102.7.11.240.589
2zdt46CMitogen-activated protein kinase 102.7.11.240.560
2o2u738Mitogen-activated protein kinase 102.7.11.240.543
3fi3JK2Mitogen-activated protein kinase 102.7.11.240.536
3eljGS7Mitogen-activated protein kinase 82.7.11.240.534
4i22IREEpidermal growth factor receptor2.7.10.10.530
3l8p0CEAngiopoietin-1 receptor2.7.10.10.525
5e8ySTUTGF-beta receptor type-22.7.11.300.524
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.523
1bygSTUTyrosine-protein kinase CSK/0.515
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.515
4awiAQ2Mitogen-activated protein kinase 82.7.11.240.515
2h96893Mitogen-activated protein kinase 82.7.11.240.510
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.509
3k5uPFQAurora kinase A2.7.11.10.509
4k33ACPFibroblast growth factor receptor 32.7.10.10.509
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.505
3w18N13Aurora kinase A2.7.11.10.504
4nka2K7Fibroblast growth factor receptor 1/0.504
4ux9ANPMitogen-activated protein kinase 82.7.11.240.504
5awmANPStress-activated protein kinase JNK2.7.11.240.504
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.502
3gxlQIGTGF-beta receptor type-12.7.11.300.501
4c4f7CEDual specificity protein kinase TTK2.7.12.10.501
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.500
3kvxFMYMitogen-activated protein kinase 102.7.11.240.500
4dgnLU2Casein kinase II subunit alpha2.7.11.10.500
4xey1N1Tyrosine-protein kinase ABL12.7.10.20.499
1pmv537Mitogen-activated protein kinase 102.7.11.240.498
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.497
2xrwANPMitogen-activated protein kinase 82.7.11.240.497
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.497
4btjADPTau-tubulin kinase 12.7.11.10.496
4id71G0Activated CDC42 kinase 1/0.496
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.495
3vs0VS0Tyrosine-protein kinase HCK2.7.10.20.495
3vs1VSATyrosine-protein kinase HCK2.7.10.20.494
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.494
3f5p741Insulin-like growth factor 1 receptor2.7.10.10.492
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.491
2vwz7X6Ephrin type-B receptor 42.7.10.10.491
2vx17X8Ephrin type-B receptor 42.7.10.10.490
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.490
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.490
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.490
4fv9E71Mitogen-activated protein kinase 12.7.11.240.489
2xs0ANPMitogen-activated protein kinase 82.7.11.240.488
5cvhADPCasein kinase II subunit alpha2.7.11.10.488
5e8xSTUTGF-beta receptor type-12.7.11.300.488
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.487
4jbqVX6Aurora kinase A2.7.11.10.487
5bvw1N1Epithelial discoidin domain-containing receptor 12.7.10.10.487
5e8wSTUTGF-beta receptor type-12.7.11.300.487
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.485
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.485
4gmy0X5Tyrosine-protein kinase JAK2/0.485
4jia1K3Tyrosine-protein kinase JAK2/0.485
5e92ANPTGF-beta receptor type-22.7.11.300.484
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.483
4mcv29KProto-oncogene tyrosine-protein kinase Src2.7.10.20.483
2wqeADPAurora kinase A2.7.11.10.482
3be9P04Casein kinase II subunit alpha2.7.11.10.482
3vquO22Dual specificity protein kinase TTK2.7.12.10.482
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.482
4jbpYPHAurora kinase A2.7.11.10.482
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.481
5dmzADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.481
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.480
4c4g7RODual specificity protein kinase TTK2.7.12.10.480
4riyADPEpidermal growth factor receptor2.7.10.10.480
4zseANPEpidermal growth factor receptor2.7.10.10.480
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.479
2wotZZGTGF-beta receptor type-12.7.11.300.479
3hmm855TGF-beta receptor type-12.7.11.300.479
4gk2L66Ephrin type-A receptor 32.7.10.10.479
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.479
4wsqKSAAP2-associated protein kinase 12.7.11.10.479
3w2sW2REpidermal growth factor receptor2.7.10.10.478
4e730NRMitogen-activated protein kinase 82.7.11.240.478
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.477
3oom507Activin receptor type-12.7.11.300.477
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.476
3gubGUBDeath-associated protein kinase 12.7.11.10.476
3t14FADSulfide-quinone reductase/0.476
1vjy460TGF-beta receptor type-12.7.11.300.475
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.475
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.475
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.475
4aotGW8Serine/threonine-protein kinase 102.7.11.10.475
1e3eNAIAlcohol dehydrogenase 41.1.1.10.474
1om1IQACasein kinase II subunit alpha2.7.11.10.474
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.474
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.473
3sz0FADSulfide-quinone reductase/0.473
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.473
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.472
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.472
2iw84SPCyclin-dependent kinase 22.7.11.220.472
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.472
3nwq2NCGag-Pol polyprotein3.4.23.160.472
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.470
2zdu446Mitogen-activated protein kinase 102.7.11.240.470
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.470
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.470
4bgg844Activin receptor type-12.7.11.300.470
4elf35IDihydrofolate reductase/0.470
4g1wG1WMitogen-activated protein kinase 82.7.11.240.470
3cgoJNOMitogen-activated protein kinase 102.7.11.240.469
3mtfA3FActivin receptor type-12.7.11.300.469
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.469
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.469
1k6pXN3Gag-Pol polyprotein3.4.23.160.468
2c6eHPMAurora kinase A2.7.11.10.468
3oriAGSSerine/threonine protein kinase/0.468
3t2zFADSulfide-quinone reductase/0.468
3uyt0CKCasein kinase I isoform delta2.7.11.10.468
2itzIREEpidermal growth factor receptor2.7.10.10.467
2pvnP63Casein kinase II subunit alpha2.7.11.10.467
2qoqANPEphrin type-A receptor 32.7.10.10.467
3tqhNDPQuinone oxidoreductase/0.467
3w1f1O5Dual specificity protein kinase TTK2.7.12.10.467
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.467
4c57FEFCyclin-G-associated kinase2.7.11.10.467
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.467
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.467
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.467
4wkqIREEpidermal growth factor receptor2.7.10.10.467
1e9hINRCyclin-dependent kinase 22.7.11.220.466
1y0s331Peroxisome proliferator-activated receptor delta/0.466
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.466
2henADPEphrin type-B receptor 22.7.10.10.466
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.466
2v7a627Tyrosine-protein kinase ABL12.7.10.20.466
3mdvCL6Cholesterol 24-hydroxylase/0.466
3zm422TDual specificity mitogen-activated protein kinase kinase 12.7.12.20.466
4c4h7RODual specificity protein kinase TTK2.7.12.10.466
4kbk1QGCasein kinase I isoform delta2.7.11.10.466
2vwx7X4Ephrin type-B receptor 42.7.10.10.465
2x2lX2LProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.465
3t2yFADSulfide-quinone reductase/0.465
4j97ACPFibroblast growth factor receptor 2/0.465
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.465
1aq1STUCyclin-dependent kinase 22.7.11.220.464
2itnANPEpidermal growth factor receptor2.7.10.10.464
2x1nX1NCyclin-dependent kinase 22.7.11.220.464
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.464
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.464
3vs3VSETyrosine-protein kinase HCK2.7.10.20.464
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.463
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.463
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.463
2vwy7X5Ephrin type-B receptor 42.7.10.10.463
3syiFADSulfide-quinone reductase/0.463
4b0gVEKAurora kinase A2.7.11.10.463
4c4iX20Dual specificity protein kinase TTK2.7.12.10.463
4j95ACPFibroblast growth factor receptor 2/0.463
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.463
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.462
2xp2VGHALK tyrosine kinase receptor2.7.10.10.462
4c58824Cyclin-G-associated kinase2.7.11.10.462
4jboWPHAurora kinase A2.7.11.10.462
4o0uADNAurora kinase A2.7.11.10.462
4ruoBIVVitamin D3 receptor A/0.462
5amnDTQProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.462
2qo9ANPEphrin type-A receptor 32.7.10.10.461
3at4CCKCasein kinase II subunit alpha2.7.11.10.461
4fkr45KCyclin-dependent kinase 22.7.11.220.461
5ap57RODual specificity protein kinase TTK2.7.12.10.461
1k6cMK1Gag-Pol polyprotein3.4.23.160.460
2c0tL3GTyrosine-protein kinase HCK2.7.10.20.460
2xvdAS6Ephrin type-B receptor 42.7.10.10.460
3ormAGSSerine/threonine protein kinase/0.460
4g7gVFVLanosterol 14-alpha-demethylase/0.460
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.460
4r21STRCytochrome P450 family 17 polypeptide 2/0.460
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.460
1h1s4SPCyclin-dependent kinase 22.7.11.220.459
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.459
2pzpACPFibroblast growth factor receptor 2/0.459
3rk507ZCyclin-dependent kinase 22.7.11.220.459
3t2kFADSulfide-quinone reductase/0.459
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.459
3wfjNAD2-dehydropantoate 2-reductase/0.459
5drdATPAurora kinase A2.7.11.10.459
1jpaANPEphrin type-B receptor 22.7.10.10.458
2igoFADPyranose 2-oxidase/0.458
2pvhP19Casein kinase II subunit alpha2.7.11.10.458
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.458
4fob0USALK tyrosine kinase receptor2.7.10.10.458
4fod0UVALK tyrosine kinase receptor2.7.10.10.458
4hnf16WCasein kinase I isoform delta2.7.11.10.458
2qocANPEphrin type-A receptor 32.7.10.10.457
3i60E86Mitogen-activated protein kinase 12.7.11.240.457
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.457
3q9xEMOCasein kinase II subunit alpha2.7.11.10.457
4yryFADGlutamate synthase, beta subunit/0.457
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.456
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.456
4anqVGHALK tyrosine kinase receptor2.7.10.10.456
4g2fC07Ephrin type-A receptor 32.7.10.10.456
4wuoNAD3-isopropylmalate dehydrogenase1.1.1.850.456
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.456
5cshATPCasein kinase II subunit alpha2.7.11.10.456
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.455
1iyzNDPProbable quinone oxidoreductase/0.455
1u4dDBQActivated CDC42 kinase 1/0.455
2pwlACPFibroblast growth factor receptor 2/0.455
3r9dX6BCyclin-dependent kinase 22.7.11.220.455
3zuxTCHTransporter/0.455
4hvi19STyrosine-protein kinase JAK32.7.10.20.455
4nk92K5Fibroblast growth factor receptor 1/0.455
4qpmADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.455
4yuqKS1Calmodulin-like domain protein kinase/0.455
1bxoPP7Penicillopepsin-13.4.23.200.454
1u54ACPActivated CDC42 kinase 1/0.454
1yw2PGJMitogen-activated protein kinase 14/0.454
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.454
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.454
3igoANPCalmodulin-domain protein kinase 1, putative/0.454
3mpaSB2Mitogen-activated protein kinase 14/0.454
3zewSTUEphrin type-B receptor 42.7.10.10.454
4dfrMTXDihydrofolate reductase1.5.1.30.454
4elg52JDihydrofolate reductase/0.454
4l7f1V5Mitogen-activated protein kinase 82.7.11.240.454
1gufNDPEnoyl-[acyl-carrier-protein] reductase 1, mitochondrial1.3.1.100.453
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.453
4btjATPTau-tubulin kinase 12.7.11.10.453
4dggI76Proto-oncogene tyrosine-protein kinase Src2.7.10.20.453
4h8nNDPNADPH-dependent conjugated polyketone reductase C2/0.453
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.453
4jr7GNPCasein kinase II subunit alpha2.7.11.10.453
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.452
1pkgADPMast/stem cell growth factor receptor Kit2.7.10.10.452
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.452
1yb5NAPQuinone oxidoreductase1.6.5.50.452
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.452
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.452
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.452
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.452
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.452
5a3bAPRSIR2 family protein/0.452
1ie4T44Transthyretin/0.451
2cmjNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.451
2d29FADAcyl-CoA dehydrogenase/0.451
2izuP01Casein kinase I isoform gamma-32.7.11.10.451
2vx07X7Ephrin type-B receptor 42.7.10.10.451
2w1fL0FAurora kinase A2.7.11.10.451
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.451
3gc9B45Mitogen-activated protein kinase 112.7.11.240.451
3kpkFADSulfide-quinone reductase/0.451
3r9hZ67Cyclin-dependent kinase 22.7.11.220.451
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.451
3vryB43Tyrosine-protein kinase HCK2.7.10.20.451
3vt8YI3Vitamin D3 receptor/0.451
4aqc88ATyrosine-protein kinase JAK2/0.451
4bi0Z0WDual specificity protein kinase TTK2.7.12.10.451
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.451
4lfiGNPCasein kinase II subunit alpha2.7.11.10.451
4o1pANPRibonuclease L/0.451
4utdACPAurora kinase A2.7.11.10.451
1dawANPCasein kinase II subunit alpha2.7.11.10.450
2xa4AZ5Tyrosine-protein kinase JAK2/0.450
2y98MIVMycinamicin IV hydroxylase/epoxidase/0.450
3t8oATPRhodopsin kinase/0.450
4ele31IDihydrofolate reductase/0.450
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.450
4q71FADBifunctional protein PutA/0.450
2hk51BMTyrosine-protein kinase HCK2.7.10.20.449
2ijmATPFocal adhesion kinase 12.7.10.20.449
2pvyACPFibroblast growth factor receptor 2/0.449
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.449
3nwxKVSGag-Pol polyprotein3.4.23.160.449
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
3t3c017Gag-Pol polyprotein3.4.23.160.449
4qmpDKISerine/threonine-protein kinase 242.7.11.10.449
4uymVOR14-alpha sterol demethylase Cyp51B/0.449
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.448
1tdrMTXDihydrofolate reductase1.5.1.30.448
2j0m4STFocal adhesion kinase 12.7.10.20.448
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.448
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.448
3efwAK8Aurora kinase A2.7.11.10.448
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.448
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.448
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.448
3uvqFS8Mitogen-activated protein kinase 14/0.448
3uzp0CKCasein kinase I isoform delta2.7.11.10.448
4b8zNAPGDP-L-fucose synthase1.1.1.2710.448
4dymIYZActivin receptor type-12.7.11.300.448
4grb0XGCasein kinase II subunit alpha2.7.11.10.448
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.448
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.448
5dqrFAD7-hydroxymethyl chlorophyll a reductase, chloroplastic1.17.7.20.448
1di8DTQCyclin-dependent kinase 22.7.11.220.447
2apgFADFlavin-dependent tryptophan halogenase PrnA1.14.19.90.447
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.447
2pvmP29Casein kinase II subunit alpha2.7.11.10.447
2q5g1FAPeroxisome proliferator-activated receptor delta/0.447
3dxjNE6DNA-directed RNA polymerase subunit beta/0.447
3dxjNE6DNA-directed RNA polymerase subunit beta'/0.447
3poz03PEpidermal growth factor receptor2.7.10.10.447
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.447
4eor4SPCyclin-dependent kinase 22.7.11.220.447
4hyu1BKMitogen-activated protein kinase 82.7.11.240.447
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.447
4jqeANPCasein kinase II subunit alpha2.7.11.10.447
4ryvZEAProtein LlR18A/0.447
1jioDEB6-deoxyerythronolide B hydroxylase/0.446
1zhwHC2Oxysterol-binding protein homolog 4/0.446
2qfxNDPIsocitrate dehydrogenase [NADP], mitochondrial1.1.1.420.446
3s4qNK0Mitogen-activated protein kinase 14/0.446
3uo50BXAurora kinase A2.7.11.10.446
4dgmAGICasein kinase II subunit alpha2.7.11.10.446
4ki8ADP60 kDa chaperonin/0.446
4m87NADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.446
4nks2M2Fibroblast growth factor receptor 1/0.446
5auwQUEDeath-associated protein kinase 12.7.11.10.446
1dxoFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.445
1pnvTYDdTDP-epi-vancosaminyltransferase2.4.1.3110.445
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.445
2bfyH1NAurora kinase B-A2.7.11.10.445
2c0oL2GTyrosine-protein kinase HCK2.7.10.20.445
2c7xNRBCytochrome P450 monooxygenase PikC/0.445
2po7CHDFerrochelatase, mitochondrial4.99.1.10.445
2y6o1N1Ephrin type-A receptor 42.7.10.10.445
3hllI45Mitogen-activated protein kinase 14/0.445
4d0l093Phosphatidylinositol 4-kinase beta2.7.1.670.445
4dn5AGSMitogen-activated protein kinase kinase kinase 142.7.11.250.445
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.445
4kba1QMCasein kinase I isoform delta2.7.11.10.445
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.445
5aaaVGHALK tyrosine kinase receptor2.7.10.10.445
5br4NADLactaldehyde reductase1.1.1.770.445
5dt3ATPAurora kinase A2.7.11.10.445
5l8lADPAurora kinase A2.7.11.10.445
1ppm0P1Penicillopepsin-13.4.23.200.444
1q8yADPSerine/threonine-protein kinase SKY12.7.11.10.444
1q97ATPSerine/threonine-protein kinase SKY12.7.11.10.444
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.444
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.444
2w17I19Cyclin-dependent kinase 22.7.11.220.444
3rukAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.444
3sdi3SDProteasome subunit beta type-53.4.25.10.444
3sdi3SDProteasome subunit beta type-63.4.25.10.444
3zep1NXTyrosine-protein kinase JAK32.7.10.20.444
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.444
4ful0VUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4ib4ERM5-hydroxytryptamine receptor 2B/0.444
4q73FADBifunctional protein PutA/0.444
1jolFFODihydrofolate reductase1.5.1.30.443
1m2rMNYCasein kinase II subunit alpha2.7.11.10.443
1w4zNAPPutative ketoacyl reductase1.3.10.443
2hog710Serine/threonine-protein kinase Chk12.7.11.10.443
2j7t274Serine/threonine-protein kinase 102.7.11.10.443
2pvlP55Casein kinase II subunit alpha2.7.11.10.443
2w05FRTCyclin-dependent kinase 22.7.11.220.443
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.443
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.443
3ddqRRCCyclin-dependent kinase 22.7.11.220.443
3mqe416Prostaglandin G/H synthase 21.14.99.10.443
3slkNDPPolyketide synthase extender module 2/0.443
3zc3NAPFerredoxin--NADP reductase1.18.1.20.443
4dgo0JWCasein kinase II subunit alpha2.7.11.10.443
4fx360KCyclin-dependent kinase 22.7.11.220.443
4gk3L87Ephrin type-A receptor 32.7.10.10.443
4hge15VTyrosine-protein kinase JAK2/0.443
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.443
4lopSB4Mitogen-activated protein kinase 14/0.443
5dn3ATPAurora kinase A2.7.11.10.443
1hiiC20Gag-Pol polyprotein/0.442
1zp9ATPRIO-type serine/threonine-protein kinase Rio12.7.11.10.442
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
2dwbANPAurora kinase A2.7.11.10.442
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.442
2q61SF1Peroxisome proliferator-activated receptor gamma/0.442
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.442
2yfxVGHALK tyrosine kinase receptor2.7.10.10.442
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.442
3nf4FADAcyl-CoA dehydrogenase domain-containing protein/0.442
3qlfPD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.442
3rkb12ZCyclin-dependent kinase 22.7.11.220.442
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.442
3zh8C58Protein kinase C iota type2.7.11.130.442
4a33MYAGlycylpeptide N-tetradecanoyltransferase/0.442
4bb432WEphrin type-B receptor 42.7.10.10.442
4bi1ZO6Dual specificity protein kinase TTK2.7.12.10.442
4c4jX21Dual specificity protein kinase TTK2.7.12.10.442
4gub0Y4Casein kinase II subunit alpha2.7.11.10.442
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4ia2BIVVitamin D3 receptor A/0.442
4loqSB4Mitogen-activated protein kinase 14/0.442
4uuxAPRCinA-like protein/0.442
1k6tXN1Gag-Pol polyprotein3.4.23.160.441
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.441
2ittAEEEpidermal growth factor receptor2.7.10.10.441
2py3ACPFibroblast growth factor receptor 2/0.441
2vu3LZECyclin-dependent kinase 22.7.11.220.441
3b6zCO7Enoyl reductase LovC10.441
3f46I2C5,10-methenyltetrahydromethanopterin hydrogenase1.12.98.20.441
3gu83GUDeath-associated protein kinase 12.7.11.10.441
3t113T1Gag-Pol polyprotein3.4.23.160.441
3zpuM8BGag-Pol polyprotein3.4.23.160.441
4a0mNADBetaine aldehyde dehydrogenase, chloroplastic1.2.1.80.441
4ansVGHALK tyrosine kinase receptor2.7.10.10.441
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.441
4g3e0WCMitogen-activated protein kinase kinase kinase 142.7.11.250.441
4wx1FDAUDP-galactopyranose mutase/0.441
4xlvACPInsulin receptor2.7.10.10.441
5c03AGSNon-receptor tyrosine-protein kinase TYK22.7.10.20.441
1lp4ANPCasein kinase II subunit alpha2.7.11.10.440
1m2pHNACasein kinase II subunit alpha2.7.11.10.440
1rv1IMZE3 ubiquitin-protein ligase Mdm26.3.20.440
1xkkFMMEpidermal growth factor receptor2.7.10.10.440
2ebaFADPutative glutaryl-CoA dehydrogenase/0.440
2itvANPEpidermal growth factor receptor2.7.10.10.440
2w1eL0EAurora kinase A2.7.11.10.440
2yn8STUEphrin type-B receptor 42.7.10.10.440
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.440
3qwbNDPProbable quinone oxidoreductase1.6.5.50.440
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.440
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.440
4c02TAKActivin receptor type-12.7.11.300.440
4eol1ROCyclin-dependent kinase 22.7.11.220.440
4hfmNAP2-alkenal reductase (NADP(+)-dependent)/0.440
4hw319GInduced myeloid leukemia cell differentiation protein Mcl-1/0.440
4lrjANPUncharacterized protein/0.440
4q72FADBifunctional protein PutA/0.440
4u8kFDAUDP-galactopyranose mutase/0.440