sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3tso | GNP | Ras-related protein Rab-25 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3tso | GNP | Ras-related protein Rab-25 | / | 1.000 | |
| 1oix | GDP | Ras-related protein Rab-11A | / | 0.568 | |
| 2fe4 | GDP | Ras-related protein Rab-6B | / | 0.534 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.522 | |
| 3lbn | GNP | GTPase HRas | / | 0.521 | |
| 4qxa | GTP | Ras-related protein Rab-9A | / | 0.521 | |
| 5c46 | GSP | Ras-related protein Rab-11A | / | 0.518 | |
| 4lhw | GNP | Ras-related protein Rab-8A | / | 0.515 | |
| 4uj3 | GNP | Ras-related protein Rab-11A | / | 0.515 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.513 | |
| 5dha | GNP | GTP-binding nuclear protein Ran | / | 0.511 | |
| 4nyi | GNP | GTPase HRas | / | 0.505 | |
| 3bbp | GTP | Ras-related protein Rab-6A | / | 0.497 | |
| 2gil | GTP | Ras-related protein Rab-6A | / | 0.496 | |
| 4uj5 | GNP | Ras-related protein Rab-11A | / | 0.496 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.494 | |
| 4o25 | GTP | GTP-binding protein Rheb | / | 0.494 | |
| 3rs5 | GNP | GTPase HRas | / | 0.493 | |
| 5jlj | GNP | GTP-binding nuclear protein Ran | / | 0.490 | |
| 3rab | GNP | Ras-related protein Rab-3A | / | 0.488 | |
| 3tnf | GNP | Ras-related protein Rab-8A | / | 0.486 | |
| 3i3s | GNP | GTPase HRas | / | 0.485 | |
| 3a6p | GTP | GTP-binding nuclear protein Ran | / | 0.484 | |
| 3v4f | GNP | GTPase HRas | / | 0.484 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.481 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.479 | |
| 3bc1 | GNP | Ras-related protein Rab-27A | / | 0.479 | |
| 5b2z | GNP | GTPase HRas | / | 0.479 | |
| 1yhn | GTP | Ras-related protein Rab-7a | / | 0.478 | |
| 3w3z | GTP | GTP-binding nuclear protein Ran | / | 0.478 | |
| 4nyj | GNP | GTPase HRas | / | 0.477 | |
| 3law | GNP | Ras-related protein Rab-7a | / | 0.476 | |
| 4dlt | GNP | GTPase HRas | / | 0.476 | |
| 3ea5 | GDP | GTP-binding nuclear protein Ran | / | 0.473 | |
| 1t91 | GTP | Ras-related protein Rab-7a | / | 0.472 | |
| 3ddc | GNP | GTPase HRas | / | 0.472 | |
| 3nbz | GTP | GTP-binding nuclear protein Ran | / | 0.472 | |
| 2zet | GTP | Ras-related protein Rab-27B | / | 0.471 | |
| 3oiv | GNP | GTPase HRas | / | 0.471 | |
| 3tkl | GTP | Ras-related protein Rab-1A | / | 0.470 | |
| 3oiu | GNP | GTPase HRas | / | 0.468 | |
| 1e96 | GTP | Ras-related C3 botulinum toxin substrate 1 | / | 0.467 | |
| 1mh1 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.467 | |
| 1vg8 | GNP | Ras-related protein Rab-7a | / | 0.465 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.465 | |
| 1lfd | GNP | GTPase HRas | / | 0.464 | |
| 2rge | GNP | GTPase HRas | / | 0.462 | |
| 1zd9 | GDP | ADP-ribosylation factor-like protein 8A | / | 0.460 | |
| 1ibr | GNP | GTP-binding nuclear protein Ran | / | 0.458 | |
| 4dlw | GNP | GTPase HRas | / | 0.458 | |
| 1uad | GNP | Ras-related protein Ral-A | / | 0.457 | |
| 2gvd | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.455 | |
| 3rs7 | GNP | GTPase HRas | / | 0.454 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.453 | |
| 3kko | GNP | Ras-related protein M-Ras | / | 0.452 | |
| 3cph | GDP | Ras-related protein SEC4 | / | 0.451 | |
| 2x19 | GTP | GTP-binding nuclear protein GSP1/CNR1 | / | 0.449 | |
| 1zc4 | GNP | Ras-related protein Ral-A | / | 0.448 | |
| 2bku | GTP | GTP-binding nuclear protein Ran | / | 0.448 | |
| 1kmq | GNP | Transforming protein RhoA | / | 0.447 | |
| 2cl6 | CAG | GTPase HRas | / | 0.446 | |
| 1g17 | GNP | Ras-related protein SEC4 | / | 0.444 | |
| 3kuc | GDP | Ras-related protein Rap-1A | / | 0.444 | |
| 1n6l | GTP | Ras-related protein Rab-5A | / | 0.443 | |
| 2cls | GTP | Rho-related GTP-binding protein Rho6 | / | 0.443 | |
| 2fg5 | GNP | Ras-related protein Rab-31 | / | 0.443 | |
| 3kkq | GDP | Ras-related protein M-Ras | / | 0.443 | |
| 4o2r | GDP | GTP-binding protein Rheb | / | 0.443 | |
| 4ol0 | GTP | GTP-binding nuclear protein Ran | / | 0.442 | |
| 1k5d | GNP | GTP-binding nuclear protein Ran | / | 0.441 | |
| 4rkf | GNP | Ras-related protein Rab-3 | / | 0.440 |