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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3tm4SAMUncharacterized protein

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3tm4SAMUncharacterized protein/1.000
3tm5SFGUncharacterized protein/0.634
3tljSAHUncharacterized protein/0.624
3friSAH16S rRNA methylase/0.495
4fr0SAMArsenic methyltransferase/0.469
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.468
10mhSAHModification methylase HhaI2.1.1.370.459
3ldgSAHUncharacterized protein/0.457
7mhtSAHModification methylase HhaI2.1.1.370.450
1q20PLOSulfotransferase family cytosolic 2B member 12.8.2.20.448
1iyzNDPProbable quinone oxidoreductase/0.446
5mhtSAHModification methylase HhaI2.1.1.370.446
1aj8COACitrate synthase/0.444
3nlqJRRNitric oxide synthase, brain1.14.13.390.444
4imw1EVNitric oxide synthase, brain1.14.13.390.444
2g1pSAHDNA adenine methylase2.1.1.720.443
2upjU02Gag-Pol polyprotein3.4.23.160.443
2wleCOAPolysialic acid O-acetyltransferase/0.443
3nljJRRNitric oxide synthase, brain1.14.13.390.443
3swrSFGDNA (cytosine-5)-methyltransferase 12.1.1.370.443
1booSAHModification methylase PvuII2.1.1.1130.441
2hs1017Protease/0.441