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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3tinADPTtl protein

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3tinADPTtl protein/1.000
3oquA8SAbscisic acid receptor PYL9/0.509
3vtdTKDVitamin D3 receptor/0.500
3vtcTK3Vitamin D3 receptor/0.498
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.497
4ia3BIVVitamin D3 receptor A/0.496
3s1dZIRCytokinin dehydrogenase 11.5.99.120.491
2hb8MVDVitamin D3 receptor/0.490
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.488
3w5rLOAVitamin D3 receptor/0.488
4a9e3PFBromodomain-containing protein 2/0.488
4ia1BIVVitamin D3 receptor A/0.488
1rk3VDXVitamin D3 receptor/0.487
2hcdBIVVitamin D3 receptor A/0.487
4ia7BIVVitamin D3 receptor A/0.487
3r9nZ68Cyclin-dependent kinase 22.7.11.220.486
3vtbTKAVitamin D3 receptor/0.485
4l9kEHFSerum albumin/0.485
4iteTEYVitamin D3 receptor/0.484
3ctj320Hepatocyte growth factor receptor2.7.10.10.483
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.482
4qms1N1Serine/threonine-protein kinase 242.7.11.10.482
1hquHBYGag-Pol polyprotein2.7.7.490.481
1rf9DBRCamphor 5-monooxygenase1.14.15.10.480
2chw039Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.480
3axwTIDCasein kinase II subunit alpha2.7.11.10.480
1jutLYDThymidylate synthase/0.479
2r0cFADPutative FAD-monooxygenase/0.478
3el7PD3Proto-oncogene tyrosine-protein kinase Src2.7.10.20.477
1ie9VDXVitamin D3 receptor/0.476
3vt7VDXVitamin D3 receptor/0.476
4fhi0S4Vitamin D3 receptor A/0.476
4g1y0VOVitamin D3 receptor A/0.476
4g2h0VQVitamin D3 receptor A/0.476
2harOCCVitamin D3 receptor/0.475
2ol4JPNEnoyl-ACP reductase/0.475
3m7rVDXVitamin D3 receptor/0.475
4fdnFADDecaprenylphosphoryl-beta-D-ribose oxidase/0.475
4l8u9AZSerum albumin/0.475
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.474
3a1l2CCCytochrome P450/0.474
1rkgVD1Vitamin D3 receptor/0.473
3vrwYS5Vitamin D3 receptor/0.473
3vt45YIVitamin D3 receptor/0.473
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.472
3w0aDS5Vitamin D3 receptor/0.472
4eb4D16Thymidylate synthase2.1.1.450.472
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.472
5bpfADPD-alanine--D-alanine ligase/0.472
1ci7CB3Thymidylate synthase2.1.1.450.471
1lhwESMSex hormone-binding globulin/0.471
3qx2X63Cyclin-dependent kinase 22.7.11.220.471
4l9q9TPSerum albumin/0.471
1tkzH16Gag-Pol polyprotein2.7.7.490.470
2fzhDH1Dihydrofolate reductase1.5.1.30.470
2hb7O1CVitamin D3 receptor/0.470
2o4jVD4Vitamin D3 receptor/0.470
3adaNADSubunit alpha of sarocosine oxidase/0.470
3lu8IQXSerum albumin/0.470
3p6oETGCamphor 5-monooxygenase1.14.15.10.470
4bcmT7ZCyclin-dependent kinase 22.7.11.220.470
4jk4DIUSerum albumin/0.470
1mb9ATPCarboxyethyl-arginine beta-lactam-synthase6.3.3.40.469
4btjATPTau-tubulin kinase 12.7.11.10.469
1ie8KH1Vitamin D3 receptor/0.468
2aazCB3Thymidylate synthase2.1.1.450.468
2hasC3OVitamin D3 receptor/0.468
2zlaVDBVitamin D3 receptor/0.468
3w5p4OAVitamin D3 receptor/0.468
3w5q3KLVitamin D3 receptor/0.467
3w5tLHPVitamin D3 receptor/0.467
4a9mP9MBromodomain-containing protein 2/0.467
4n6bCOAUncharacterized protein/0.467
4nkvAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.467
1pjkANPCasein kinase II subunit alpha2.7.11.10.466
1rjkVDZVitamin D3 receptor/0.466
1s4dSAHUroporphyrinogen-III C-methyltransferase2.1.1.1070.466
1txiTX5Vitamin D3 receptor/0.466
3w0gW07Vitamin D3 receptor/0.466
1j39UPGDNA beta-glucosyltransferase/0.465
1rkhVD2Vitamin D3 receptor/0.465
2vq5LDPS-norcoclaurine synthase/0.465
2zb8IMNProstaglandin reductase 21.3.1.480.465
2zl9VDAVitamin D3 receptor/0.465
3a7hATPSerine/threonine-protein kinase 242.7.11.10.465
3pvzNADUDP-N-acetylglucosamine 4,6-dehydratase/0.465
3rni21ZCyclin-dependent kinase 22.7.11.220.465
3vrtYS2Vitamin D3 receptor/0.465
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.465
1db1VDXVitamin D3 receptor/0.464
1k6cMK1Gag-Pol polyprotein3.4.23.160.464
2c6kDT2Cyclin-dependent kinase 22.7.11.220.464
2pmdGNPTranslation initiation factor 2 subunit gamma/0.464
2zjwREFCasein kinase II subunit alpha2.7.11.10.464
3cd57HI3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.464
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.464
3vt5YI2Vitamin D3 receptor/0.464
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.464
4g20484Vitamin D3 receptor A/0.464
4ia2BIVVitamin D3 receptor A/0.464
4ifcADPSerine/threonine-protein kinase PRP4 homolog2.7.11.10.464
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.464
1gufNDPEnoyl-[acyl-carrier-protein] reductase 1, mitochondrial1.3.1.100.463
1j3kWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.463
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.463
1xddAAYIntegrin alpha-L/0.463
2vd5BI8Myotonin-protein kinase2.7.11.10.463
2x7jTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.463
3kpzZNEVitamin D3 receptor/0.463
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.463
3vt3VDXVitamin D3 receptor/0.463
3vt65YIVitamin D3 receptor/0.463
4fhh0U3Vitamin D3 receptor A/0.463
4y95746Tyrosine-protein kinase/0.463
5kgpACOPredicted acetyltransferase/0.463
1b87ACOAac(6')-Ii protein/0.462
1xu7CPSCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.462
1zarADPRIO-type serine/threonine-protein kinase Rio22.7.11.10.462
2hbhXE4Vitamin D3 receptor A/0.462
3dr1C5DVitamin D3 receptor A/0.462
3drcMTXDihydrofolate reductase1.5.1.30.462
3nux3NVCyclin-dependent kinase 62.7.11.220.462
3w0jT08Vitamin D3 receptor/0.462
1ep4S11Gag-Pol polyprotein2.7.7.490.461
1finATPCyclin-dependent kinase 22.7.11.220.461
1yp4ADQGlucose-1-phosphate adenylyltransferase small subunit, chloroplastic/amyloplastic2.7.7.270.461
2dteNAIGlucose 1-dehydrogenase related protein/0.461
2hamC33Vitamin D3 receptor/0.461
2ntvP1HEnoyl-[acyl-carrier-protein] reductase [NADH]/0.461
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.461
3lfsA07Cyclin-dependent kinase 22.7.11.220.461
3up0D7SaceDAF-12/0.461
3vruYS3Vitamin D3 receptor/0.461
3w2cN15Aurora kinase A2.7.11.10.461
4iayADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.461
4kz01UJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
1eyqNARChalcone--flavonone isomerase 15.5.1.60.460
1h0w207Cyclin-dependent kinase 22.7.11.220.460
1kvkATPMevalonate kinase2.7.1.360.460
1uh5TCLEnoyl-ACP reductase/0.460
2vv9IM9Cyclin-dependent kinase 22.7.11.220.460
3up3XCAaceDAF-12/0.460
3w0iO11Vitamin D3 receptor/0.460
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
4q71FADBifunctional protein PutA/0.460
4uyf73BBromodomain-containing protein 2/0.460
1ijhFADCholesterol oxidase1.1.3.60.459
2hekGDPUncharacterized protein/0.459
3s1cZIRCytokinin dehydrogenase 11.5.99.120.459
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
4jlj1NMDeoxycytidine kinase2.7.1.740.459
4nb6444Nuclear receptor ROR-gamma/0.459
5ifyUMPGlucose-1-phosphate thymidylyltransferase/0.459
1hvyD16Thymidylate synthase2.1.1.450.458
1ruoCMPcAMP-activated global transcriptional regulator CRP/0.458
2bxe1FLSerum albumin/0.458
2o4rVD5Vitamin D3 receptor/0.458
2wuuNHWGlycylpeptide N-tetradecanoyltransferase/0.458
3cgfJNFMitogen-activated protein kinase 102.7.11.240.458
3rukAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.458
3t9i3T9Serine/threonine-protein kinase pim-12.7.11.10.458
4ajwVWNPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform2.7.1.1530.458
4d58BI9Focal adhesion kinase 12.7.10.20.458
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.458
4uymVOR14-alpha sterol demethylase Cyp51B/0.458
2c4g514Cyclin-dependent kinase 22.7.11.220.457
2j4z626Aurora kinase A2.7.11.10.457
2jfz003Glutamate racemase/0.457
2r3mSCXCyclin-dependent kinase 22.7.11.220.457
3dfcANPDeath-associated protein kinase 12.7.11.10.457
3h1jSMACytochrome b/0.457
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.457
4e5kNADPhosphonate dehydrogenase1.20.1.10.457
4g1d0VKVitamin D3 receptor A/0.457
4o701QKBromodomain-containing protein 4/0.457
4wzyATPMaltokinase2.7.1.1750.457
3a783EVVitamin D3 receptor/0.456
3czr3CZCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.456
3i1fGCPTranslation initiation factor 2 subunit gamma/0.456
3lfqA28Cyclin-dependent kinase 22.7.11.220.456
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.456
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4at0FADPossible succinate dehydrogenase/0.456
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.456
4g1z0VPVitamin D3 receptor A/0.456
4q0a4OAVitamin D3 receptor A/0.456
4ryvZEAProtein LlR18A/0.456
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.456
1mqbANPEphrin type-A receptor 22.7.10.10.455
1qiqACCIsopenicillin N synthase1.21.3.10.455
2hziJINTyrosine-protein kinase ABL12.7.10.20.455
2lbdREARetinoic acid receptor gamma/0.455
2o7pNAPRiboflavin biosynthesis protein RibD/0.455
2p2i608Vascular endothelial growth factor receptor 22.7.10.10.455
2uxuNARHTH-type transcriptional regulator TtgR/0.455
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.455
2y7jB49Phosphorylase b kinase gamma catalytic chain, liver/testis isoform2.7.11.190.455
3rak03ZCyclin-dependent kinase 22.7.11.220.455
3w0hW12Vitamin D3 receptor/0.455
3zkyWT4Isopenicillin N synthase1.21.3.10.455
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.455
4ic7ANPMitogen-activated protein kinase 72.7.11.240.455
4jl5ADPAdenylate kinase/0.455
1tduCB3Thymidylate synthase/0.454
1zsnTN2Enoyl-ACP reductase/0.454
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.454
3begANPSRSF protein kinase 12.7.11.10.454
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.454
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.454
3q92XNBKetohexokinase/0.454
3qyw6PBMitogen-activated protein kinase 12.7.11.240.454
3r1sX73Cyclin-dependent kinase 22.7.11.220.454
3t2kFADSulfide-quinone reductase/0.454
3vrvYSDVitamin D3 receptor/0.454
4hw219HInduced myeloid leukemia cell differentiation protein Mcl-1/0.454
4hw319GInduced myeloid leukemia cell differentiation protein Mcl-1/0.454
4iarERM5-hydroxytryptamine receptor 1B/0.454
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.454
5auxKMPDeath-associated protein kinase 12.7.11.10.454
1hb1OCVIsopenicillin N synthase1.21.3.10.453
1n4vFADCholesterol oxidase1.1.3.60.453
1zxlJP1Enoyl-ACP reductase/0.453
2j5xGSPADP-ribosylation factor 6/0.453
2ntjP1HEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.453
2pvyACPFibroblast growth factor receptor 2/0.453
2yk2YJXHeat shock protein HSP 90-alpha/0.453
3ldfSAHUncharacterized protein/0.453
3x04GNPPhosphatidylinositol 5-phosphate 4-kinase type-2 beta2.7.1.1490.453
4itfTFYVitamin D3 receptor/0.453
4n4t2GVTankyrase-12.4.2.300.453
4ruoBIVVitamin D3 receptor A/0.453
1b4vFADCholesterol oxidase1.1.3.60.452
1e8hADPVanillyl-alcohol oxidase1.1.3.380.452
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.452
1lsoNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.452
1q99ANPSerine/threonine-protein kinase SKY12.7.11.10.452
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.452
1xzqFONtRNA modification GTPase MnmE3.6.50.452
2ban357Gag-Pol polyprotein2.7.7.490.452
2r3lSCWCyclin-dependent kinase 22.7.11.220.452
2w05FRTCyclin-dependent kinase 22.7.11.220.452
2yy8SAMtRNA (cytidine(56)-2'-O)-methyltransferase/0.452
2z3uCRRCytochrome P450/0.452
3d3eD3ECorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.452
3l0lHC3Nuclear receptor ROR-gamma/0.452
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.452
3stw2TDMethylketone synthase I/0.452
3u9dATPActin, alpha skeletal muscle/0.452
4aguD15Cyclin-dependent kinase-like 1/0.452
4fob0USALK tyrosine kinase receptor2.7.10.10.452
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.452
5a28MYAGlycylpeptide N-tetradecanoyltransferase/0.452
5e8wSTUTGF-beta receptor type-12.7.11.300.452
1ha3MAUElongation factor Tu-A/0.451
1hw5CMPcAMP-activated global transcriptional regulator CRP/0.451
1s0zEB1Vitamin D3 receptor/0.451
1tktH12Gag-Pol polyprotein2.7.7.490.451
2g97DGBNicotinamide phosphoribosyltransferase2.4.2.120.451
2h55DZ8Heat shock protein HSP 90-alpha/0.451
2hc4VDXVitamin D3 receptor A/0.451
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.451
2kceD16Thymidylate synthase/0.451
2x7hPFNProstaglandin reductase 310.451
3bqdDAYGlucocorticoid receptor/0.451
3p6nDSOCamphor 5-monooxygenase1.14.15.10.451
3tdaPN0Cytochrome P450 2D6/0.451
3w9rA8SAbscisic acid receptor PYL9/0.451
4kwi1TJReductase homolog/0.451
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.451
1dhrNADDihydropteridine reductase1.5.1.340.450
1k6pXN3Gag-Pol polyprotein3.4.23.160.450
1kk4ACOStreptogramin A acetyltransferase2.3.10.450
1qknRALEstrogen receptor beta/0.450
2jg7NADAntiquitin/0.450
2vxoXMPGMP synthase [glutamine-hydrolyzing]6.3.5.20.450
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.450
2ykcYKCHeat shock protein HSP 90-alpha/0.450
2zdt46CMitogen-activated protein kinase 102.7.11.240.450
3cgoJNOMitogen-activated protein kinase 102.7.11.240.450
3cnjFADCholesterol oxidase1.1.3.60.450
3deyDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.450
3klmDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.450
3qdd94MHeat shock protein HSP 90-alpha/0.450
3u5sFADFAD-linked sulfhydryl oxidase ALR1.8.3.20.450
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
4anmWULCasein kinase II subunit alpha2.7.11.10.450
4foc0UUALK tyrosine kinase receptor2.7.10.10.450
4iaq2GM5-hydroxytryptamine receptor 1B/0.450
4ii5ADPCyclin-dependent kinase 22.7.11.220.450
4rupH97Vitamin D3 receptor A/0.450
4u0oMTALipoyl synthase 2/0.450
4xwrFADCholesterol oxidase1.1.3.60.450
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.450
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.450
1cd2FOLDihydrofolate reductase1.5.1.30.449
1cdeGARPhosphoribosylglycinamide formyltransferase/0.449
1s7gNADNAD-dependent protein deacylase 2/0.449
1tvoFRZMitogen-activated protein kinase 12.7.11.240.449
1zg32HIIsoflavone 4'-O-methyltransferase/0.449
2bunFADAppA protein/0.449
2c7gFADNADPH-ferredoxin reductase FprA1.18.1.20.449
2izt23DCasein kinase I isoform gamma-32.7.11.10.449
2pvmP29Casein kinase II subunit alpha2.7.11.10.449
2wpwACOOrf14/0.449
2x2lX2LProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.449
2y30SM8Putative repressor SimReg2/0.449
3ad9NADSubunit alpha of sarocosine oxidase/0.449
3at4CCKCasein kinase II subunit alpha2.7.11.10.449
3cjtSAHRibosomal protein L11 methyltransferase2.1.10.449
3fmn530Mitogen-activated protein kinase 14/0.449
3v49PK0Androgen receptor/0.449
3w0c6DSVitamin D3 receptor/0.449
4a9hTVPBromodomain-containing protein 2/0.449
4e5yNDPGDP-L-fucose synthase1.1.1.2710.449
4fklCK2Cyclin-dependent kinase 22.7.11.220.449
4gueQCTRibosomal protein S6 kinase alpha-32.7.11.10.449
4hgs15GCasein kinase I isoform gamma-32.7.11.10.449
4l23X6KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.449
4qe6JN3Bile acid receptor/0.449
5ahsCOAAcyl-CoA dehydrogenase/0.449
1blzACVIsopenicillin N synthase1.21.3.10.448
1pr9NAPL-xylulose reductase1.1.1.100.448
1re9DSOCamphor 5-monooxygenase1.14.15.10.448
2a0cCK9Cyclin-dependent kinase 22.7.11.220.448
2ftoCB3Thymidylate synthase/0.448
2i40BLZCyclin-dependent kinase 22.7.11.220.448
2py3ACPFibroblast growth factor receptor 2/0.448
2ydwWSHBromodomain-containing protein 2/0.448
3gu4ANPDeath-associated protein kinase 12.7.11.10.448
3kvxFMYMitogen-activated protein kinase 102.7.11.240.448
3m0eATPTranscriptional regulator (NtrC family)/0.448
3p6pA6BCamphor 5-monooxygenase1.14.15.10.448
3qm4PN0Cytochrome P450 2D6/0.448
3v94WYQPhosphodiesterase/0.448
3w0pADPHygromycin-B 4-O-kinase2.7.1.1630.448
3w0sANPHygromycin-B 4-O-kinase2.7.1.1630.448
4af3VX6Aurora kinase B2.7.11.10.448
4qi5FADCellobiose dehydrogenase/0.448
4xey1N1Tyrosine-protein kinase ABL12.7.10.20.448
4ysjADPCalmodulin-like domain protein kinase/0.448
1nnuTCTEnoyl-ACP reductase/0.447
1y5rC0RCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.447
2a5yATPCell death protein 4/0.447
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.447
2fzwNADAlcohol dehydrogenase class-31.1.1.10.447
2gs7ANPEpidermal growth factor receptor2.7.10.10.447
2r3fSC8Cyclin-dependent kinase 22.7.11.220.447
2uvyGVIcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.447
2w98P1ZProstaglandin reductase 21.3.1.480.447
2y53NAP3,4-dehydroadipyl-CoA semialdehyde dehydrogenase/0.447
2zlcVDXVitamin D3 receptor/0.447
3oqfS51Renin3.4.23.150.447
3sz0FADSulfide-quinone reductase/0.447
4e730NRMitogen-activated protein kinase 82.7.11.240.447
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.447
4l2zS7MS-adenosylmethionine synthase/0.447
4wq4ATPtRNA N6-adenosine threonylcarbamoyltransferase/0.447
5cdgPFBAlcohol dehydrogenase E chain1.1.1.10.447
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.446
1jlaTNKGag-Pol polyprotein2.7.7.490.446
1kqwRTLCellular retinol-binding protein type II/0.446
1p4mADPRiboflavin kinase2.7.1.260.446
1ppjANYCytochrome b/0.446
1uy7PU4Heat shock protein HSP 90-alpha/0.446
1wnbNAIGamma-aminobutyraldehyde dehydrogenase1.2.1.190.446
2ca0PXICytochrome P450 monooxygenase PikC/0.446
2cduFADNADH oxidase/0.446
2ekpNAD2-deoxy-D-gluconate 3-dehydrogenase/0.446
2fr0NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.446
2iyaZIOOleandomycin glycosyltransferase/0.446
2izrBRKCasein kinase I isoform gamma-32.7.11.10.446
2oaxSNLMineralocorticoid receptor/0.446
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.446
2xviFADPutative flavin-containing monooxygenase/0.446
3jrxS1AAcetyl-CoA carboxylase 2/0.446
3jynNDPQuinone oxidoreductase/0.446
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
3n1s5GPPurine nucleoside phosphoramidase/0.446
3njoP2MAbscisic acid receptor PYR1/0.446
3qzhX69Cyclin-dependent kinase 22.7.11.220.446
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.446
3u4uLNHCasein kinase II subunit alpha2.7.11.10.446
3w0yDS4Vitamin D3 receptor/0.446
4a31MYAGlycylpeptide N-tetradecanoyltransferase/0.446
4fehFADDecaprenylphosphoryl-beta-D-ribose oxidase/0.446
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.446
4mgkCMPRap guanine nucleotide exchange factor 4/0.446
4tuvCPZCytochrome P450 1191.140.446
4twnB96Ephrin type-A receptor 32.7.10.10.446
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.446
3reyXACAdenosine receptor A2a/0.446
1gjrNAPFerredoxin--NADP reductase1.18.1.20.445
1hnvTBOGag-Pol polyprotein2.7.7.490.445
1n06ADPRiboflavin kinase2.7.1.260.445
1o1vTCHGastrotropin/0.445
1pkfEPDEpothilone C/D epoxidase1.140.445
1s6qTPBGag-Pol polyprotein2.7.7.490.445
2a4zBYMPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
2gekGDPPhosphatidyl-myo-inositol mannosyltransferase2.4.1.570.445
2r3iSCFCyclin-dependent kinase 22.7.11.220.445
2yk2YJWHeat shock protein HSP 90-alpha/0.445
3bfa9ODOdorant binding protein ASP1/0.445
3dejRXCCaspase-33.4.22.560.445
3gbuATPUncharacterized sugar kinase PH14592.7.10.445
3hz137DHeat shock protein HSP 90-alpha/0.445
3junAKDPhenazine biosynthesis protein A/B/0.445
3r6sCMPCRP-like cAMP-activated global transcriptional regulator/0.445
3t2yFADSulfide-quinone reductase/0.445
3tnwF18Cyclin-dependent kinase 22.7.11.220.445
4b7sQLECytochrome P450 monooxygenase PikC/0.445
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.445
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4gevCB3Thymidylate synthase/0.445
4jloADPAdenylate kinase/0.445
4ks7X4ZSerine/threonine-protein kinase PAK 62.7.11.10.445
4o4eATPKinase/0.445
5c03AGSNon-receptor tyrosine-protein kinase TYK22.7.10.20.445
5jlaNADPutative short-chain dehydrogenase/reductase/0.445
5kjePFBAlcohol dehydrogenase E chain1.1.1.10.445
3emlZMAAdenosine receptor A2a/0.445
1kgjFL8Transthyretin/0.444
1sqvUHDCytochrome b/0.444
2cgpCMPcAMP-activated global transcriptional regulator CRP/0.444
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.444
2po7CHDFerrochelatase, mitochondrial4.99.1.10.444
2qa2FADPolyketide oxygenase CabE/0.444
2rkiTT1Gag-Pol polyprotein2.7.7.490.444
2vmyFFOSerine hydroxymethyltransferase/0.444
2w4iVGAGlutamate racemase/0.444
2xrwANPMitogen-activated protein kinase 82.7.11.240.444
3hz5Z64Heat shock protein HSP 90-alpha/0.444
3nj0PYVAbscisic acid receptor PYL2/0.444
4fhj0TZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4g1cCNANAD-dependent protein deacylase sirtuin-5, mitochondrial/0.444
4gvjADPNon-receptor tyrosine-protein kinase TYK22.7.10.20.444
4o71CPBBromodomain-containing protein 4/0.444
1bk0ACVIsopenicillin N synthase1.21.3.10.443
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
1mg5NAIAlcohol dehydrogenase1.1.1.10.443
1pd9CO4Dihydrofolate reductase1.5.1.30.443
1qi1NAPNADP-dependent glyceraldehyde-3-phosphate dehydrogenase1.2.1.90.443
1uymPU3Heat shock protein HSP 90-beta/0.443
2azzTCHPhospholipase A2, major isoenzyme3.1.1.40.443
2bujSTUSerine/threonine-protein kinase 16/0.443
2bx8AZQSerum albumin/0.443
2c6hPXICytochrome P450 monooxygenase PikC/0.443
2ghmLICMitogen-activated protein kinase 14/0.443
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.443
2vcmM11Isopenicillin N synthase1.21.3.10.443
3dv0TPWPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.443
3dv0TPWPyruvate dehydrogenase E1 component subunit beta1.2.4.10.443
3g493G4Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.443
3ol5SAWCamphor 5-monooxygenase1.14.15.10.443
3oq6PFBAlcohol dehydrogenase E chain1.1.1.10.443
3p6mDSOCamphor 5-monooxygenase1.14.15.10.443
3q5iANPProtein kinase, putative/0.443
3qaiXNNKetohexokinase/0.443
3sqq99ZCyclin-dependent kinase 22.7.11.220.443
3vcyUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.443
3vspEK8Peroxisome proliferator-activated receptor gamma/0.443
3vt8YI3Vitamin D3 receptor/0.443
3vt9YI4Vitamin D3 receptor/0.443
3zh8C58Protein kinase C iota type2.7.11.130.443
4b7dQLECytochrome P450 monooxygenase PikC/0.443
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.443
4fv8E63Mitogen-activated protein kinase 12.7.11.240.443
4haiI23Bifunctional epoxide hydrolase 23.1.3.760.443
4la0198Serum albumin/0.443
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.443
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.443
1c6yMK1Protease/0.442
1disBDMDihydrofolate reductase1.5.1.30.442
1pp9SMACytochrome b/0.442
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.442
1rfqLARActin, alpha skeletal muscle/0.442
1w8cN69Cyclin-dependent kinase 22.7.11.220.442
2b53D23Cyclin-dependent kinase 22.7.11.220.442
2bjsACVIsopenicillin N synthase1.21.3.10.442
2c7xNRBCytochrome P450 monooxygenase PikC/0.442
2jb4A14Isopenicillin N synthase1.21.3.10.442
2p33J07Mitogen-activated protein kinase 102.7.11.240.442
2pg0FADAcyl-CoA dehydrogenase/0.442
2ykeYKEHeat shock protein HSP 90-alpha/0.442
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.442
3ezrEZRCyclin-dependent kinase 22.7.11.220.442
3gu83GUDeath-associated protein kinase 12.7.11.10.442
3lkhLT6Genome polyprotein2.7.7.480.442
3qtsX46Cyclin-dependent kinase 22.7.11.220.442
3qxpX64Cyclin-dependent kinase 22.7.11.220.442
3uyt0CKCasein kinase I isoform delta2.7.11.10.442
3vdqNAD3-hydroxybutyrate dehydrogenase/0.442
3vsoEK1Peroxisome proliferator-activated receptor gamma/0.442
3zkuHCVIsopenicillin N synthase1.21.3.10.442
4b1fKRHGlutamate racemase/0.442
4ctaATPCinA-like protein/0.442
4dtaADNAPH(2'')-Id/0.442
4ead0NPThymidine phosphorylase2.4.2.40.442
4eqgA5AHistidine triad nucleotide-binding protein 130.442
4g210VPVitamin D3 receptor A/0.442
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.442
4jvf17XRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.442
4xivACPChemotaxis protein CheA2.7.13.30.442
4xxgFADCholesterol oxidase1.1.3.60.442
5av2KMPDeath-associated protein kinase 12.7.11.10.442
5cb3APRO-acetyl-ADP-ribose deacetylase/0.442
1ahiCHO7-alpha-hydroxysteroid dehydrogenase1.1.1.1590.441
1dfoFFOSerine hydroxymethyltransferase2.1.2.10.441
1diuBDMDihydrofolate reductase1.5.1.30.441
1e8wQUEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
1hk5T44Serum albumin/0.441
1mxtFAECholesterol oxidase1.1.3.60.441
1s1vTNKGag-Pol polyprotein2.7.7.490.441
1sejF89Bifunctional dihydrofolate reductase-thymidylate synthase/0.441
1trgCB3Thymidylate synthase/0.441
1v1bATP2-dehydro-3-deoxygluconokinase2.7.1.450.441
1y9r1CAMineralocorticoid receptor/0.441
2a5uQYTPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
2bu9HFVIsopenicillin N synthase1.21.3.10.441
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.441
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.441
2yerTQ1Serine/threonine-protein kinase Chk12.7.11.10.441
2ykiYKIHeat shock protein HSP 90-alpha/0.441
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.441
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.441
3g7jGTXGlutathione transferase GST1-4/0.441
3lf0ATPNitrogen regulatory protein P-II/0.441
3pe2E1BCasein kinase II subunit alpha2.7.11.10.441
3qtzX42Cyclin-dependent kinase 22.7.11.220.441
3r7uX96Cyclin-dependent kinase 22.7.11.220.441
3r7yZ04Cyclin-dependent kinase 22.7.11.220.441
3sheI85MAP kinase-activated protein kinase 32.7.11.10.441
3stuDK3Methylketone synthase I/0.441
3t14FADSulfide-quinone reductase/0.441
3zewSTUEphrin type-B receptor 42.7.10.10.441
4a9iP9IBromodomain-containing protein 2/0.441
4a9rRU5Serine/threonine-protein kinase Chk22.7.11.10.441
4cdmFO1Deoxyribodipyrimidine photolyase/0.441
4gk4L90Ephrin type-A receptor 32.7.10.10.441
4gkh0J9Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.441
4j2wFADKynurenine 3-monooxygenase/0.441
4jvnYUGEstrogen sulfotransferase2.8.2.40.441
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.441
4nj32KDCyclin-dependent kinase 22.7.11.220.441
4rekFADCholesterol oxidase1.1.3.60.441
5g53NECAdenosine receptor A2a/0.441
3sn6P0GBeta-2 adrenergic receptor/0.441
1lhnAONSex hormone-binding globulin/0.440
1suiSAHCaffeoyl-CoA O-methyltransferase2.1.1.1040.440
1sx4ADP60 kDa chaperonin/0.440
2a1tFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.440
2cd8PXICytochrome P450 monooxygenase PikC/0.440
2hwrDRDPeroxisome proliferator-activated receptor gamma/0.440
2jahNDPClavaldehyde dehydrogenase/0.440
2r0pK2CPutative FAD-monooxygenase/0.440
2w17I19Cyclin-dependent kinase 22.7.11.220.440
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.440
2yutNAPPutative short-chain oxidoreductase/0.440
3aw9NADNAD-dependent epimerase/dehydratase/0.440
3bc3OPTCathepsin L13.4.22.150.440
3bgxMEFThymidylate synthase/0.440
3cs9NILTyrosine-protein kinase ABL12.7.10.20.440
3dpd41APhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
3fzsB96Protein-tyrosine kinase 2-beta2.7.10.20.440
3gkjHC3Niemann-Pick C1 protein/0.440
3h3sH15Collagen type IV alpha-3-binding protein/0.440
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.440
3w0nANPHygromycin-B 4-O-kinase2.7.1.1630.440
3zsi52PMitogen-activated protein kinase 14/0.440
4bb3KKAIsopenicillin N synthase1.21.3.10.440
4bqg50QHeat shock protein HSP 90-alpha/0.440
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.440
4f9b0SYCell division cycle 7-related protein kinase2.7.11.10.440
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.440
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.440
4idgNADPutative UDP-glucose 4-epimerase/0.440
4r20AERCytochrome P450 family 17 polypeptide 2/0.440
4xgxADPFAD:protein FMN transferase/0.440