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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3tfyMET_LEU_GLY_PRON-alpha-acetyltransferase 502.3.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3tfyMET_LEU_GLY_PRON-alpha-acetyltransferase 502.3.11.000
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.505
4hwkNAPSepiapterin reductase1.1.1.1530.503
4jtqNAPAldo-keto reductase family 1 member C2/0.498
3uzzASD3-oxo-5-beta-steroid 4-dehydrogenase/0.496
2g1r3IGRenin3.4.23.150.495
3up0D7SaceDAF-12/0.495
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.494
1qorNDPQuinone oxidoreductase 1/0.489
5jlaNADPutative short-chain dehydrogenase/reductase/0.489
1g6kNADGlucose 1-dehydrogenase1.1.1.470.488
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.487
2g1s4IGRenin3.4.23.150.486
3bxxQUEDihydroflavonol 4-reductase1.1.1.2190.486
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.486
3fktSIIBeta-secretase 13.4.23.460.484
1x1bSAHC-20 methyltransferase/0.483
2vqbFADPutative flavin-containing monooxygenase/0.483
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.481
4nbwNADShort-chain dehydrogenase/reductase SDR/0.481
4q72FADBifunctional protein PutA/0.481
4rvgTYDD-mycarose 3-C-methyltransferase/0.481
1m2jAPRNAD-dependent protein deacylase 1/0.480
2xi4AFTAcetylcholinesterase3.1.1.70.480
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.479
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.479
2ociTYCValacyclovir hydrolase3.10.479
2xlpFADPutative flavin-containing monooxygenase/0.478
3o56ZG1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.478
3pkdY10Methionine aminopeptidase 2/0.478
2j3qTFLAcetylcholinesterase3.1.1.70.477
2xvfFADPutative flavin-containing monooxygenase/0.477
3lqfNADGalactitol dehydrogenase/0.477
2g1y5IGRenin3.4.23.150.476
2q2qNADBeta-D-hydroxybutyrate dehydrogenase/0.476
2v13C40Renin3.4.23.150.476
4l5b1UXDeoxycytidine kinase2.7.1.740.476
3pqbVGPPutative oxidoreductase/0.475
3q43D66M1 family aminopeptidase3.4.110.475
3uzzTES3-oxo-5-beta-steroid 4-dehydrogenase/0.475
3v2uATPProtein GAL3/0.475
1gky5GPGuanylate kinase2.7.4.80.474
4a2zVIQGlycylpeptide N-tetradecanoyltransferase/0.474
4e32DWNMethyltransferase/0.474
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.473
2c1zU2FAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.473
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.473
2xuqTZ4Acetylcholinesterase3.1.1.70.473
3ch6311Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.473
4n3r2GUTankyrase-12.4.2.300.473
2hizLIJBeta-secretase 13.4.23.460.472
3lpjZ75Beta-secretase 13.4.23.460.472
4zzi1NSNAD-dependent protein deacetylase sirtuin-13.5.10.472
1hb1OCVIsopenicillin N synthase1.21.3.10.471
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.471
3ndjJHZMethyltransferase/0.471
3wqmB29Diterpene synthase3.1.7.80.471
1wkgPOI[LysW]-aminoadipate semialdehyde transaminase/0.470
2xupTZ5Acetylcholinesterase3.1.1.70.470
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.470
4oztP1AEcdysone receptor, putative/0.470
1h22E10Acetylcholinesterase3.1.1.70.469
1hb3SCVIsopenicillin N synthase1.21.3.10.469
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.469
3cgtBCDCyclomaltodextrin glucanotransferase2.4.1.190.469
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.469
3vyfVYFRenin3.4.23.150.469
4bv9NDPKetimine reductase mu-crystallin1.5.1.250.469
4dvi2IWTankyrase-12.4.2.300.469
4e2yJHZMethyltransferase/0.469
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.468
2g226IGRenin3.4.23.150.468
3c3xNAPEugenol synthase 11.1.1.3180.468
3dopNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.468
3dv5BAVBeta-secretase 13.4.23.460.468
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.468
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.468
3qwbNDPProbable quinone oxidoreductase1.6.5.50.468
4o1mNADEnoyl-acyl carrier reductase/0.468
1u65CP0Acetylcholinesterase3.1.1.70.467
2g1o2IGRenin3.4.23.150.467
2ozrGG1Collagenase 33.4.240.467
2q2vNADBeta-D-hydroxybutyrate dehydrogenase/0.467
2rbeZMGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.467
2rqfJH3Hemolymph juvenile hormone binding protein/0.467
2xuiTZ5Acetylcholinesterase3.1.1.70.467
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.467
3w8eNAD3-hydroxybutyrate dehydrogenase/0.467
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.467
4usqFADPyridine nucleotide-disulfide oxidoreductase/0.467
1odcA8BAcetylcholinesterase3.1.1.70.466
2gv8NDPThiol-specific monooxygenase1.14.130.466
2wsa646Glycylpeptide N-tetradecanoyltransferase/0.466
3akn11DFatty acid-binding protein, intestinal/0.466
3autNAIGlucose 1-dehydrogenase 41.1.1.470.466
3f1kNAPUncharacterized oxidoreductase YciK10.466
3uzxAOX3-oxo-5-beta-steroid 4-dehydrogenase/0.466
1eveE20Acetylcholinesterase3.1.1.70.465
1ot7IU5Bile acid receptor/0.465
3bk2U5PRibonuclease J/0.465
3d91REMRenin3.4.23.150.465
3vswR31Renin3.4.23.150.465
4o9cCOAAcetyl-CoA acetyltransferase2.3.1.90.465
5hwoHMGHydroxymethylglutaryl-CoA synthase/0.465
2il2LIXRenin3.4.23.150.464
2jb4A14Isopenicillin N synthase1.21.3.10.464
3cavCI23-oxo-5-beta-steroid 4-dehydrogenase/0.464
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.464
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.464
3lpiZ74Beta-secretase 13.4.23.460.464
3q8uADPNucleoside diphosphate kinase/0.464
3uaxNOSPurine nucleoside phosphorylase DeoD-type/0.464
3vg10GTBeta-secretase 13.4.23.460.464
3zbrNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.464
4lxa1YSBeta-secretase 13.4.23.460.464
1nuuNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.463
1yqzCOACoenzyme A disulfide reductase/0.463
3vydVYDRenin3.4.23.150.463
5epoTUD7-alpha-hydroxysteroid deydrogenase/0.463
4u140HKMuscarinic acetylcholine receptor M3/0.463
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.462
1k7fIAVTryptophan synthase alpha chain/0.462
2wzySQXSoluble acetylcholine receptor/0.462
3pkbY16Methionine aminopeptidase 2/0.462
4dc0NDPPutative ketoacyl reductase1.3.10.462
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.462
1ma0NADAlcohol dehydrogenase class-31.1.1.10.461
1q23FUAChloramphenicol acetyltransferase2.3.1.280.461
1xe65FPPlasmepsin-23.4.23.390.461
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.461
2qimZEAClass 10 plant pathogenesis-related protein/0.461
2zatNAPDehydrogenase/reductase SDR family member 41.1.1.1840.461
2zbaZBATrichothecene 3-O-acetyltransferase/0.461
3bhiNAPCarbonyl reductase [NADPH] 11.1.1.1840.461
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.461
4q73FADBifunctional protein PutA/0.461
5irnADPNucleotide binding oligomerization domain containing 2/0.461
5jqhCAUBeta-2 adrenergic receptor/0.461
1rneC60Renin3.4.23.150.460
1x1dSAHC-20 methyltransferase/0.460
2p83MR0Beta-secretase 13.4.23.460.460
4bftZVTPantothenate kinase2.7.1.330.460
4flkY10Methionine aminopeptidase 1/0.460
4mr92BXGamma-aminobutyric acid type B receptor subunit 1/0.460
4rh10TTSpore photoproduct lyase/0.460
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.460
1lnmDTXBilin-binding protein/0.459
2b3dFADModulator of drug activity B/0.459
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.459
3cosNADAlcohol dehydrogenase 41.1.1.10.459
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
3f63GTXGlutathione transferase GST1-4/0.459
3vsxR32Renin3.4.23.150.459
4araC56Acetylcholinesterase3.1.1.70.459
4eqrCOACoenzyme A disulfide reductase/0.459
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
4jayNAPUDP-N-acetylenolpyruvoylglucosamine reductase/0.459
4kxjP34Nucleoprotein/0.459
4xwtU5PRibonuclease J/0.459
3sn6P0GBeta-2 adrenergic receptor/0.459
1pqc444Oxysterols receptor LXR-beta/0.458
1qrpHH0Pepsin A-43.4.23.10.458
2fdpFRPBeta-secretase 13.4.23.460.458
3bg7FADPyranose 2-oxidase/0.458
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.458
4bfzZVZPantothenate kinase2.7.1.330.458
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.458
4j7xNAPSepiapterin reductase1.1.1.1530.458
5dbgNADIridoid synthase1.3.1.990.458
1w6hTITPlasmepsin-23.4.23.390.457
1xe55FEPlasmepsin-23.4.23.390.457
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
2r8oT5XTransketolase 1/0.457
3jynNDPQuinone oxidoreductase/0.457
3v0o4GWHisto-blood group ABO system transferase/0.457
4b65NDPL-ornithine N(5)-monooxygenase/0.457
4n4v2GYTankyrase-12.4.2.300.457
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.456
2b4yAPRNAD-dependent protein deacylase sirtuin-5, mitochondrial/0.456
2cekN8TAcetylcholinesterase3.1.1.70.456
2g247IGRenin3.4.23.150.456
2i4qUA4Renin3.4.23.150.456
2pobGW4Peroxisome proliferator-activated receptor gamma/0.456
2xujTZ5Acetylcholinesterase3.1.1.70.456
2xvhFADPutative flavin-containing monooxygenase/0.456
3b6pTMPThree-prime repair exonuclease 13.1.11.20.456
3b6zCO7Enoyl reductase LovC10.456
3zm62GNUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.456
4bb3KKAIsopenicillin N synthase1.21.3.10.456
4drjRAPSerine/threonine-protein kinase mTOR2.7.11.10.456
4drjRAPPeptidyl-prolyl cis-trans isomerase FKBP45.2.1.80.456
3nyaJTZBeta-2 adrenergic receptor/0.456
1h5qNAPNADP-dependent mannitol dehydrogenase1.1.1.1380.455
1m2gAPRNAD-dependent protein deacylase 1/0.455
1xjqADPBifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 12.7.1.250.455
2c12FADNitroalkane oxidase1.7.3.10.455
2cmjNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.455
2hdjNDPAldo-keto reductase family 1 member C2/0.455
2w6cBM4Acetylcholinesterase3.1.1.70.455
2x9dITCTetracycline repressor protein class D/0.455
2xlrFADPutative flavin-containing monooxygenase/0.455
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.455
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.455
3vdqNAD3-hydroxybutyrate dehydrogenase/0.455
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.455
5dp2NAPCurF/0.455
2rh1CAUBeta-2 adrenergic receptor/0.455
1psa0ZLPepsin A3.4.23.10.454
2c20NADUDP-glucose 4-epimerase/0.454
2ewmNAD(S)-1-Phenylethanol dehydrogenase1.1.1.3110.454
2g6pHM2Methionine aminopeptidase 1/0.454
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.454
2gvdFKPAdenylate cyclase type 2/0.454
2gvdFKPAdenylate cyclase type 5/0.454
2h3wHC5Carnitine O-acetyltransferase2.3.1.70.454
2r9w23CBeta-lactamase3.5.2.60.454
2vceU2FUDP-glycosyltransferase 72B1/0.454
3bi2FADPolyamine oxidase FMS1/0.454
3cid318Beta-secretase 13.4.23.460.454
3own3OWRenin3.4.23.150.454
3qvpFADGlucose oxidase1.1.3.40.454
4d89BXDBeta-secretase 13.4.23.460.454
4dc1NDPPutative ketoacyl reductase1.3.10.454
4dpf0LGBeta-secretase 13.4.23.460.454
4gdcNDPUDP-galactopyranose mutase/0.454
4gz612VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.454
4uymVOR14-alpha sterol demethylase Cyp51B/0.454
1fm4DXCMajor pollen allergen Bet v 1-L/0.453
1oxoIK2Aspartate aminotransferase, mitochondrial2.6.1.10.453
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.453
1reqDCAMethylmalonyl-CoA mutase large subunit5.4.99.20.453
1xkdNAPIsocitrate dehydrogenase [NADP]/0.453
2iviACWIsopenicillin N synthase1.21.3.10.453
2xaaNADSecondary alcohol dehydrogenase/0.453
2xveFADPutative flavin-containing monooxygenase/0.453
2zevB71Geranylgeranyl pyrophosphate synthase/0.453
2zynBCDPeriplasmic binding protein/0.453
3cic316Beta-secretase 13.4.23.460.453
3fapARDPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.453
3fapARDSerine/threonine-protein kinase mTOR2.7.11.10.453
3nxqRX4Angiotensin-converting enzyme3.2.10.453
4a6rTA8Probable aminotransferase/0.453
4eqsCOACoenzyme A disulfide reductase/0.453
5dldUD1UDP-N-Acetylglucosamine 2-epimerase/0.453
1ae1NAPTropinone reductase 1/0.452
1w6jR71Lanosterol synthase5.4.99.70.452
1x1cSAHC-20 methyltransferase/0.452
1xh5R68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
2aouCQAHistamine N-methyltransferase2.1.1.80.452
2ckmAA7Acetylcholinesterase3.1.1.70.452
2ed4NAD4-hydroxyphenylacetate 3-monooxygenase reductase component1.5.1.360.452
2xuoTZ4Acetylcholinesterase3.1.1.70.452
3pndFADFAD:protein FMN transferase/0.452
4cf6CBDNAD(P)H dehydrogenase [quinone] 11.6.5.20.452
4driRAPSerine/threonine-protein kinase mTOR2.7.11.10.452
4driRAPPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.452
4pl0ANPMicrocin-J25 export ATP-binding/permease protein McjD/0.452
4ybnFADFlavin-nucleotide-binding protein/0.452
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.452
1cdoNADAlcohol dehydrogenase 11.1.1.10.451
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.451
1vl8NAPOxidoreductase, short chain dehydrogenase/reductase family/0.451
2f3eAXQBeta-secretase 13.4.23.460.451
2q1wNADPutative nucleotide sugar epimerase/ dehydratase/0.451
2uxoTACHTH-type transcriptional regulator TtgR/0.451
2z4w749Geranylgeranyl pyrophosphate synthase/0.451
2zvbSAHPrecorrin-3 C17-methyltransferase/0.451
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3pkaY02Methionine aminopeptidase 2/0.451
3qlsNDPDihydrofolate reductase1.5.1.30.451
3vyeVYERenin3.4.23.150.451
4a81DXCMajor pollen allergen Bet v 1-A/0.451
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.451
4dmmNAP3-oxoacyl-[acyl-carrier-protein] reductase/0.451
4fcd0T6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.451
4l4xNDPAmphI/0.451
4n3l2FNProthrombin3.4.21.50.451
4rgqNDPGlycerol-1-phosphate dehydrogenase [NAD(P)+]/0.451
5e5h0T1Succinyl-CoA:acetate CoA-transferase/0.451
5d6lCAUBeta-2 adrenergic receptor/0.451
1n5dNDPCarbonyl reductase [NADPH] 1/0.450
1rwbNADGlucose 1-dehydrogenase1.1.1.470.450
2gesCOKPantothenate kinase2.7.1.330.450
2pg0FADAcyl-CoA dehydrogenase/0.450
3f90FMNFlavodoxin/0.450
3fcjFADNitroalkane oxidase1.7.3.10.450
3gluLYS_VAL_METNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.450
3k5gBJCBeta-secretase 13.4.23.460.450
3o4rNAPDehydrogenase/reductase SDR family member 41.1.1.1840.450
4dz5NAPAldo-keto reductase family 1 member C3/0.450
4lxk1YTBeta-secretase 13.4.23.460.450
4mo2FADUDP-galactopyranose mutase/0.450
4twnB96Ephrin type-A receptor 32.7.10.10.450
1dx6GNTAcetylcholinesterase3.1.1.70.449
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.449
1ut6A8NAcetylcholinesterase3.1.1.70.449
2dvlFADAcyl-CoA dehydrogenase/0.449
2e0nSAHPrecorrin-2 C20-methyltransferase/0.449
2p8uCOAHydroxymethylglutaryl-CoA synthase, cytoplasmic2.3.3.100.449
2y60M8FIsopenicillin N synthase1.21.3.10.449
3a1cACPProbable copper-exporting P-type ATPase A3.6.3.540.449
3oetNADErythronate-4-phosphate dehydrogenase/0.449
3skgPB8Beta-secretase 13.4.23.460.449
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.449
4drn0MCPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.449
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.449
4jsr1NQNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.449
4q0kGA3Phytohormone-binding protein/0.449
1qjfACSIsopenicillin N synthase1.21.3.10.448
1rx0FADIsobutyryl-CoA dehydrogenase, mitochondrial1.3.990.448
2ha6SCKAcetylcholinesterase3.1.1.70.448
2ixkTDOdTDP-4-dehydrorhamnose 3,5-epimerase5.1.3.130.448
2qs3UBEGlutamate receptor ionotropic, kainate 1/0.448
2v58LZJBiotin carboxylase6.3.4.140.448
2ztlNADD(-)-3-hydroxybutyrate dehydrogenase/0.448
2ztvNADD(-)-3-hydroxybutyrate dehydrogenase/0.448
3bi5FADPolyamine oxidase FMS1/0.448
3gw9VNILanosterol 14-alpha-demethylase/0.448
3lpkZ76Beta-secretase 13.4.23.460.448
4a84DXCMajor pollen allergen Bet v 1-A/0.448
4xbfFADLysine-specific histone demethylase 1A10.448
4z3dNDPCarbonyl reductase [NADPH] 11.1.1.1840.448
5hwpCOAHydroxymethylglutaryl-CoA synthase/0.448
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.447
1w6rGNTAcetylcholinesterase3.1.1.70.447
1x7gNAPPutative ketoacyl reductase1.3.10.447
2fznFADBifunctional protein PutA1.5.5.20.447
2j9fTHV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.447
2j9fTHV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial1.2.4.40.447
2oxiNADAlcohol dehydrogenase E chain1.1.1.10.447
2zb3NDPProstaglandin reductase 21.3.1.480.447
3ai3NDPNADPH-sorbose reductase/0.447
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.447
3d3xARG_ILE_MET_GLU_NH2Type E botulinum toxin/0.447
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
3ggoNAIPrephenate dehydrogenase/0.447
3pfdFDAAcyl-CoA dehydrogenase FadE25/0.447
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.447
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.447
4d04NAPPhenylacetone monooxygenase1.14.13.920.447
4j7uNAPSepiapterin reductase1.1.1.1530.447
4nv10FXFormyl transferase/0.447
4xguADPPutative pachytene checkpoint protein 2/0.447
1mj9COAHistone acetyltransferase ESA1/0.446
1nbiSAMGlycine N-methyltransferase2.1.1.200.446
1obnASVIsopenicillin N synthase1.21.3.10.446
1pfyMSPMethionine--tRNA ligase6.1.1.100.446
1vrqFMNSubunit alpha of sarocosine oxidase/0.446
1vrqFMNSubunit beta of sarcosine oxidase/0.446
1xs7MMIBeta-secretase 13.4.23.460.446
2du8FADD-amino-acid oxidase1.4.3.30.446
2hkoFADLysine-specific histone demethylase 1A10.446
2jfhLK1UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.446
2q1tNADPutative nucleotide sugar epimerase/ dehydratase/0.446
2q9fC3SCholesterol 24-hydroxylase/0.446
3gqvNAPEnoyl reductase LovC10.446
3hmvHBTcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.446
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.446
3kmyD8YBeta-secretase 13.4.23.460.446
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3nsh957Beta-secretase 13.4.23.460.446
3qbjNXZDipeptidyl peptidase 4/0.446
4fkzUD1UDP-N-acetylglucosamine 2-epimerase5.1.3.140.446
4fse0VABeta-secretase 13.4.23.460.446
4i0i957Beta-secretase 13.4.23.460.446
1cf3FADGlucose oxidase1.1.3.40.445
1fmlRTLRetinol dehydratase/0.445
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.445
1q83TZ5Acetylcholinesterase3.1.1.70.445
1q84TZ4Acetylcholinesterase3.1.1.70.445
2g21L1BRenin3.4.23.150.445
2ien017Gag-Pol polyprotein3.4.23.160.445
2ivnANPtRNA N6-adenosine threonylcarbamoyltransferase/0.445
2ph6712Beta-secretase 13.4.23.460.445
2pncCLUPrimary amine oxidase, liver isozyme/0.445
2trtTACTetracycline repressor protein class D/0.445
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.445
3k5c0BIBeta-secretase 13.4.23.460.445
3s5wFADL-ornithine N(5)-monooxygenase/0.445
3zoiM2WIsopenicillin N synthase1.21.3.10.445
4cax646Glycylpeptide N-tetradecanoyltransferase2.3.1.970.445
4dro0MDPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.445
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.445
4ey7E20Acetylcholinesterase3.1.1.70.445
4jdcNADProbable pyrroline-5-carboxylate dehydrogenase RocA/0.445
4nbuNAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.445
4nesUD1UDP-N-acetylglucosamine 2-epimerase5.1.3.140.445
4psbGA3Cytokinin-specific binding protein/0.445
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.445
1caqDPSStromelysin-13.4.24.170.444
1d9i00PProthrombin3.4.21.50.444
1fapRAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.444
1fapRAPSerine/threonine-protein kinase mTOR2.7.11.10.444
1kkq471Peroxisome proliferator-activated receptor alpha/0.444
1osvCHCBile acid receptor/0.444
1pq944BOxysterols receptor LXR-beta/0.444
1x27ASP_TYR_VAL_HIS_PTRTyrosine-protein kinase Lck2.7.10.20.444
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.444
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.444
2xufTZ4Acetylcholinesterase3.1.1.70.444
2yltNAPPhenylacetone monooxygenase1.14.13.920.444
2zu9GDPMannosyl-3-phosphoglycerate synthase2.4.1.2170.444
3b1dPLSBetaC-S lyase/0.444
3eksCY9Actin-5C/0.444
3ohh3HHBeta-secretase 13.4.23.460.444
3vf60H6Glucokinase2.7.1.20.444
4b1rITCTetracycline repressor protein class D/0.444
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.444
4dfg0JVGag-Pol polyprotein3.4.23.160.444
4k9h1QUBeta-secretase 13.4.23.460.444
4l0qNADAlcohol dehydrogenase class-3/0.444
4m0f1YKAcetylcholinesterase3.1.1.70.444
6ctsCICCitrate synthase, mitochondrial2.3.3.10.444
3vw7VPXProteinase-activated receptor 1/0.444
1krrACOGalactoside O-acetyltransferase2.3.1.180.443
1t9gFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.443
1tiqCOASpermidine/spermine N(1)-acetyltransferase/0.443
1uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.443
2g25TDKPyruvate dehydrogenase E1 component1.2.4.10.443
2jf0HBPAcetylcholinesterase3.1.1.70.443
2ouyCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
2vprTDCTetracycline repressor protein class H/0.443
2wo7ASVIsopenicillin N synthase1.21.3.10.443
3owaFADAcyl-CoA dehydrogenase/0.443
3sni546cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
4egbNADdTDP-glucose 4,6-dehydratase/0.443
4fllYZ6Methionine aminopeptidase 1/0.443
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.443
4wdfA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.443
1c7oPPGHemolysin/0.442
1jf0CZHObelin/0.442
1n4pCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.442
1vf3GDNGlutathione S-transferase 32.5.1.180.442
1w4lGL8Acetylcholinesterase3.1.1.70.442
1zgbA1EAcetylcholinesterase3.1.1.70.442
2bu9HFVIsopenicillin N synthase1.21.3.10.442
2ea2F77Methionine aminopeptidase 2/0.442
2ikuLIYRenin3.4.23.150.442
2r8pT6FTransketolase 1/0.442
2vijC44Beta-secretase 13.4.23.460.442
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.442
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3dm6757Beta-secretase 13.4.23.460.442
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3hdqGDUUDP-galactopyranose mutase/0.442
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.442
3own3OXRenin3.4.23.150.442
3pkeY10Methionine aminopeptidase 2/0.442
3zhuTD8Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.442
4b4w9L9Bifunctional protein FolD/0.442
4bc7FADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.442
4enhFVXCholesterol 24-hydroxylase/0.442
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.442
4twrNADNAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase/0.442
4yshFADGlycine oxidase/0.442
5ao1DG3Deoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.442
5e7oMGDDMSO reductase family type II enzyme, molybdopterin subunit/0.442
5fl3ADPPili retraction protein PilT/0.442
1f4fTP3Thymidylate synthase/0.441
1kw0H4BPhenylalanine-4-hydroxylase1.14.16.10.441
1qtiGNTAcetylcholinesterase3.1.1.70.441
1ro6ROLcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.441
1snyNAPLD36273p/0.441
2geuCOKPantothenate kinase2.7.1.330.441
2uzfCAA1,4-dihydroxy-2-naphthoyl-CoA synthase/0.441
2vbdV10Isopenicillin N synthase1.21.3.10.441
2wf4ZY4Beta-secretase 13.4.23.460.441
3buvNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.441
3h7uNAPNADPH-dependent aldo-keto reductase, chloroplastic/0.441
3udj092Beta-secretase 13.4.23.460.441
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.441
4b64NAPL-ornithine N(5)-monooxygenase/0.441
4c2z646Glycylpeptide N-tetradecanoyltransferase 1/0.441
4ewo996Beta-secretase 13.4.23.460.441
4kvmSER_ALA_SER_GLU_1XEN-terminal acetyltransferase A complex catalytic subunit ard12.3.1.880.441
4yntFDAGlucose oxidase, putative/0.441
4z5wILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.441
1g8jMGDArsenite oxidase subunit AioA1.20.9.10.440
1kf6FADFumarate reductase flavoprotein subunit1.3.5.40.440
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.440
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.440
1w4zNAPPutative ketoacyl reductase1.3.10.440
2bd0NAPSepiapterin reductase/0.440
2g5w8PG12-oxophytodienoate reductase 31.3.1.420.440
2givACOHistone acetyltransferase KAT8/0.440
2yphQQY2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.440
3a3gDLZLumazine protein/0.440
3ab1FADFerredoxin--NADP reductase1.18.1.20.440
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
3g70A5TRenin3.4.23.150.440
3ivcFG4Pantothenate synthetase6.3.2.10.440
3q44D50M1 family aminopeptidase3.4.110.440
3r6sCMPCRP-like cAMP-activated global transcriptional regulator/0.440
3r7kFDAProbable acyl CoA dehydrogenase/0.440
4b68FADL-ornithine N(5)-monooxygenase/0.440
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
4lnbED5CaaX farnesyltransferase beta subunit Ram1/0.440
4oxyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
4uugPXGBranched-chain amino acid aminotransferase, putative/0.440
4x28FDAAcyl-CoA dehydrogenase FadE26/0.440
4x28FDAAcyl-CoA dehydrogenase FadE27/0.440
5idwNAPShort-chain dehydrogenase/reductase SDR/0.440