sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3tfq | 07M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3tfq | 07M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 1.000 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.631 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.631 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.593 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.587 | |
| 3d3e | D3E | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.585 | |
| 3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.562 | |
| 2rbe | ZMG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.561 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.556 | |
| 2ilt | NN1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.555 | |
| 1osv | CHC | Bile acid receptor | / | 0.538 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.538 | |
| 3bzu | A21 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.534 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.532 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.531 | |
| 1xu7 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.526 | |
| 3d5q | T30 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.517 | |
| 3oq1 | 3OQ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.517 | |
| 1xu9 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.515 | |
| 3lz6 | A0D | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.513 | |
| 1ot7 | IU5 | Bile acid receptor | / | 0.508 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.507 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.507 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.504 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.504 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.503 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.499 | |
| 1kqw | RTL | Cellular retinol-binding protein type II | / | 0.498 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.496 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.496 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.494 | |
| 5epo | TUD | 7-alpha-hydroxysteroid deydrogenase | / | 0.493 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.492 | |
| 1r6g | 442 | Thyroid hormone receptor beta | / | 0.491 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.490 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.490 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.490 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.489 | |
| 3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.489 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.489 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.489 | |
| 1zdw | FLV | Prenyltransferase | / | 0.488 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.488 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.488 | |
| 1kvo | OAP | Phospholipase A2, membrane associated | / | 0.487 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.487 | |
| 1kt3 | RTL | Retinol-binding protein 4 | / | 0.486 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.485 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.484 | |
| 2bik | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.484 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.484 | |
| 4iae | 1DX | Alr2278 protein | / | 0.484 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.483 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.483 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.483 | |
| 4iah | 1DX | Alr2278 protein | / | 0.483 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.483 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.483 | |
| 1fml | RTL | Retinol dehydratase | / | 0.482 | |
| 3p6o | ETG | Camphor 5-monooxygenase | 1.14.15.1 | 0.482 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.482 | |
| 4bzn | UGX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.482 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.482 | |
| 4i2q | 1BT | Gag-Pol polyprotein | 2.7.7.49 | 0.481 | |
| 3cxw | 7CP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.480 | |
| 3ey4 | 352 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.480 | |
| 3gcn | TYR_GLN_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.480 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.479 | |
| 4qe6 | JN3 | Bile acid receptor | / | 0.479 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.478 | |
| 3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.477 | |
| 4f7i | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.477 | |
| 4pd6 | URI | Nucleoside permease | / | 0.477 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.477 | |
| 1re9 | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.476 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.476 | |
| 4mq2 | 2C4 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | 2.7.12.1 | 0.476 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.475 | |
| 1xal | NAD | 3-dehydroquinate synthase | / | 0.475 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.475 | |
| 2prh | 238 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.475 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.475 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.475 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.475 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.475 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.474 | |
| 2bel | CBO | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.474 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.474 | |
| 3p6n | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.474 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.474 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.474 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.474 | |
| 4mlh | VO2 | Glucokinase | 2.7.1.2 | 0.474 | |
| 1e1m | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.473 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 3d5f | L41 | Peroxisome proliferator-activated receptor delta | / | 0.473 | |
| 3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.473 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.473 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.473 | |
| 4zow | CLM | Multidrug transporter MdfA | / | 0.473 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.473 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.472 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.472 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.472 | |
| 4i3v | NAD | Aldehyde dehydrogenase (NAD+) | / | 0.472 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.472 | |
| 1eio | GCH | Gastrotropin | / | 0.471 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.471 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.471 | |
| 2xls | FAD | Putative flavin-containing monooxygenase | / | 0.471 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.471 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.471 | |
| 4kwi | 1TJ | Reductase homolog | / | 0.471 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.471 | |
| 4wuo | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.471 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.470 | |
| 2wug | HPK | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.470 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.470 | |
| 3h1v | TK1 | Glucokinase | 2.7.1.2 | 0.470 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.470 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.470 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.470 | |
| 1e7a | PFL | Serum albumin | / | 0.469 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.469 | |
| 3p9t | TCL | Repressor | / | 0.469 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.469 | |
| 4ixf | IXF | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 4l4x | NDP | AmphI | / | 0.469 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.469 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 1chw | HXC | Chalcone synthase 2 | 2.3.1.74 | 0.468 | |
| 1knu | YPA | Peroxisome proliferator-activated receptor gamma | / | 0.468 | |
| 1lri | CLR | Beta-elicitin cryptogein | / | 0.468 | |
| 1tys | DHF | Thymidylate synthase | / | 0.468 | |
| 1xuo | LA1 | Integrin alpha-L | / | 0.468 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.468 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.468 | |
| 1q4x | G24 | Thyroid hormone receptor beta | / | 0.467 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.467 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.467 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.467 | |
| 3iog | SDF | Metallo-beta-lactamase type 2 | / | 0.467 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.467 | |
| 2hko | FAD | Lysine-specific histone demethylase 1A | 1 | 0.466 | |
| 3cy2 | MB9 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.466 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.466 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.466 | |
| 4hl1 | ZZ7 | Metallo-beta-lactamase type 2 | / | 0.466 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.466 | |
| 4jx1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.466 | |
| 4l9q | 9TP | Serum albumin | / | 0.466 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.465 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.465 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.465 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.465 | |
| 4qi7 | FAD | Cellobiose dehydrogenase | / | 0.465 | |
| 1fwm | CB3 | Thymidylate synthase | / | 0.464 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.464 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.464 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.464 | |
| 3q7d | NPX | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.464 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.464 | |
| 4c3y | FAD | 3-ketosteroid dehydrogenase | / | 0.464 | |
| 4cax | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.464 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.464 | |
| 4jvm | XDI | Estrogen sulfotransferase | 2.8.2.4 | 0.464 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.464 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.464 | |
| 1fm7 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.463 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.463 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.463 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.463 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.463 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.463 | |
| 4xe6 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.463 | |
| 1ahi | CHO | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.462 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.462 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.462 | |
| 1o1v | TCH | Gastrotropin | / | 0.462 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.462 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.462 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.462 | |
| 3amb | VX6 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.462 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.462 | |
| 4qi4 | FAD | Cellobiose dehydrogenase | / | 0.462 | |
| 1ek2 | CDU | Bifunctional epoxide hydrolase 2 | / | 0.461 | |
| 1ml6 | GBX | Glutathione S-transferase A2 | 2.5.1.18 | 0.461 | |
| 2ghl | LIB | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.461 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.461 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.461 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.461 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.461 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.461 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.461 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.461 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.461 | |
| 4yt5 | H4M | H(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338 | / | 0.461 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.461 | |
| 1equ | EQI | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.460 | |
| 1fx9 | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.460 | |
| 1men | GAR | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.460 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 2j14 | GNI | Peroxisome proliferator-activated receptor delta | / | 0.460 | |
| 2jd1 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.460 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.460 | |
| 3a25 | SAM | tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase | / | 0.460 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.460 | |
| 3cnj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.460 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.460 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.460 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.460 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.460 | |
| 3p6p | A6B | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 3uhm | RFN | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.460 | |
| 4e37 | NDP | Catalase | 1.11.1.6 | 0.460 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.460 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.459 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.459 | |
| 1rrm | APR | Lactaldehyde reductase | 1.1.1.77 | 0.459 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.459 | |
| 2vtt | LZD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 2ydw | WSH | Bromodomain-containing protein 2 | / | 0.459 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.459 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.459 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.459 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.459 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.459 | |
| 1kt7 | RTL | Retinol-binding protein 4 | / | 0.458 | |
| 1pox | FAD | Pyruvate oxidase | 1.2.3.3 | 0.458 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.458 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.458 | |
| 2hwr | DRD | Peroxisome proliferator-activated receptor gamma | / | 0.458 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.458 | |
| 2uxx | FAJ | Lysine-specific histone demethylase 1A | 1 | 0.458 | |
| 2wuf | KEM | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.458 | |
| 3ldf | SAH | Uncharacterized protein | / | 0.458 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.458 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.458 | |
| 1dv2 | ATP | Biotin carboxylase | 6.3.4.14 | 0.457 | |
| 1rf9 | DBR | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.457 | |
| 1uae | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.457 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.457 | |
| 2w0b | CMW | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.457 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.457 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.457 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.457 | |
| 4e4q | RRH | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
| 4g2h | 0VQ | Vitamin D3 receptor A | / | 0.457 | |
| 4hfm | NAP | 2-alkenal reductase (NADP(+)-dependent) | / | 0.457 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.457 | |
| 4n1g | CEI | Obelin | / | 0.457 | |
| 4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.457 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.457 | |
| 1o8c | NDP | Probable acrylyl-CoA reductase AcuI | 1.3.1.84 | 0.456 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.456 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.456 | |
| 1s9e | ADB | Gag-Pol polyprotein | 2.7.7.49 | 0.456 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.456 | |
| 2q4w | FAD | Cytokinin dehydrogenase 7 | 1.5.99.12 | 0.456 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.456 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.456 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.456 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.456 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.456 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.455 | |
| 2c3i | IYZ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.455 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.455 | |
| 2wue | KEK | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.455 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.455 | |
| 4ez8 | DHF | Thymidylate synthase | 2.1.1.45 | 0.455 | |
| 4g34 | 924 | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.455 | |
| 1ee9 | NAD | Methylenetetrahydrofolate dehydrogenase [NAD(+)] | 1.5.1.15 | 0.454 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.454 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.454 | |
| 3ant | S82 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.454 | |
| 3bi2 | FAD | Polyamine oxidase FMS1 | / | 0.454 | |
| 3oev | 3OE | Proteasome subunit beta type-5 | 3.4.25.1 | 0.454 | |
| 3oev | 3OE | Proteasome subunit beta type-6 | 3.4.25.1 | 0.454 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.454 | |
| 3up0 | D7S | aceDAF-12 | / | 0.454 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.454 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.453 | |
| 1bxo | PP7 | Penicillopepsin-1 | 3.4.23.20 | 0.453 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.453 | |
| 1hf3 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.453 | |
| 1ikv | EFZ | Gag-Pol polyprotein | 2.7.7.49 | 0.453 | |
| 1nq1 | 4HY | Thyroid hormone receptor beta | / | 0.453 | |
| 2aib | ERG | Beta-elicitin cinnamomin | / | 0.453 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.453 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 2vg7 | NNI | Gag-Pol polyprotein | 2.7.7.49 | 0.453 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 3jzi | JZL | Biotin carboxylase | 6.3.4.14 | 0.453 | |
| 4b7d | QLE | Cytochrome P450 monooxygenase PikC | / | 0.453 | |
| 4c2j | COA | 3-ketoacyl-CoA thiolase, mitochondrial | 2.3.1.16 | 0.453 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.453 | |
| 4knz | CB3 | Thymidylate synthase | / | 0.453 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.453 | |
| 5a3c | NAD | SIR2 family protein | / | 0.453 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.453 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1soz | VAL_TYR_GLN_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.452 | |
| 1tl3 | H20 | Gag-Pol polyprotein | 2.7.7.49 | 0.452 | |
| 1ve3 | SAM | Uncharacterized protein | / | 0.452 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.452 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.452 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 2vq7 | FAD | Putative flavin-containing monooxygenase | / | 0.452 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.452 | |
| 3f5p | 741 | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.452 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.452 | |
| 3nx4 | NAP | Putative oxidoreductase | / | 0.452 | |
| 3qf9 | NM8 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.452 | |
| 3tnl | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.452 | |
| 3zux | TCH | Transporter | / | 0.452 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.452 | |
| 4k9v | 6AW | Cytochrome P450 3A4 | / | 0.452 | |
| 4n6z | 2HW | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.452 | |
| 4xnh | ACO | N-terminal acetyltransferase A complex subunit NAT5 | 2.3.1 | 0.452 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.452 | |
| 4s0v | SUV | Orexin receptor type 2 | / | 0.452 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.451 | |
| 1e7q | NAP | GDP-L-fucose synthase | / | 0.451 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.451 | |
| 1kce | CB3 | Thymidylate synthase | / | 0.451 | |
| 1kt6 | RTL | Retinol-binding protein 4 | / | 0.451 | |
| 1q6n | P90 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.451 | |
| 1zz2 | B11 | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 2bl4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.451 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.451 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.451 | |
| 2ic5 | GNP | Ras-related C3 botulinum toxin substrate 3 | / | 0.451 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.451 | |
| 3ojx | NAP | NADPH--cytochrome P450 reductase | / | 0.451 | |
| 3up3 | XCA | aceDAF-12 | / | 0.451 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1al8 | DHP | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.450 | |
| 1an5 | CB3 | Thymidylate synthase | / | 0.450 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.450 | |
| 1kl2 | FON | Serine hydroxymethyltransferase | / | 0.450 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.450 | |
| 1qip | GNB | Lactoylglutathione lyase | 4.4.1.5 | 0.450 | |
| 1vru | AAP | Gag-Pol polyprotein | 2.7.7.49 | 0.450 | |
| 2c7x | NRB | Cytochrome P450 monooxygenase PikC | / | 0.450 | |
| 2iya | ZIO | Oleandomycin glycosyltransferase | / | 0.450 | |
| 2xsz | ATP | RuvB-like 2 | 3.6.4.12 | 0.450 | |
| 2zno | S44 | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 3bi5 | FAD | Polyamine oxidase FMS1 | / | 0.450 | |
| 3rhh | NAP | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase | / | 0.450 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.450 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.450 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 4u2s | FDA | Cholesterol oxidase | 1.1.3.6 | 0.450 | |
| 5doz | NDP | JamJ | / | 0.450 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.449 | |
| 2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 2p33 | J07 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.449 | |
| 2pob | GW4 | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 3ar6 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.449 | |
| 3cyz | 9OD | Pheromone-binding protein ASP1 | / | 0.449 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.449 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.449 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.449 | |
| 3gco | VAL_TYR_GLN_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.449 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.449 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.449 | |
| 3lu8 | IQX | Serum albumin | / | 0.449 | |
| 3p6m | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 3v9v | 21L | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.449 | |
| 3zkp | ERB | Erythromycin C-12 hydroxylase | 1.14.13.154 | 0.449 | |
| 4c3x | FAD | 3-ketosteroid dehydrogenase | / | 0.449 | |
| 4cnj | FAD | L-amino acid oxidase | / | 0.449 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.449 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.449 | |
| 4gah | 0ET | Acyl-coenzyme A thioesterase THEM4 | 3.1.2.2 | 0.449 | |
| 4jlc | SU6 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.449 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.448 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.448 | |
| 1qvn | FRI | Interleukin-2 | / | 0.448 | |
| 1rek | B8L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.448 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.448 | |
| 2b0m | 201 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.448 | |
| 2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.448 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.448 | |
| 2v1a | FMN | NPH1-1 | / | 0.448 | |
| 3bgr | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 3lan | KBT | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 3lkh | LT6 | Genome polyprotein | 2.7.7.48 | 0.448 | |
| 3pe6 | ZYH | Monoglyceride lipase | / | 0.448 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.448 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.448 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.448 | |
| 4efu | EFU | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 4eji | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.448 | |
| 4fkv | 61K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.448 | |
| 4i7f | NVE | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.448 | |
| 4mq1 | 2C3 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | 2.7.12.1 | 0.448 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.448 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.448 | |
| 5l7d | CLR | Smoothened homolog | / | 0.448 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.448 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.447 | |
| 1dtp | APU | Diphtheria toxin | / | 0.447 | |
| 1hnj | MLC | 3-oxoacyl-[acyl-carrier-protein] synthase 3 | / | 0.447 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1ihi | IU5 | Aldo-keto reductase family 1 member C2 | / | 0.447 | |
| 1tkz | H16 | Gag-Pol polyprotein | 2.7.7.49 | 0.447 | |
| 1w78 | PD8 | Dihydrofolate synthase/folylpolyglutamate synthase | 6.3.2.12 | 0.447 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.447 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.447 | |
| 2f4j | VX6 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.447 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.447 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.447 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 2w4q | CBW | Prostaglandin reductase 2 | 1.3.1.48 | 0.447 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.447 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 3bgz | VX3 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.447 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.447 | |
| 3med | 65B | Gag-Pol polyprotein | 2.7.7.49 | 0.447 | |
| 3uwl | FOZ | Thymidylate synthase | / | 0.447 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.447 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.447 | |
| 4acm | 7YG | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 4aqc | 88A | Tyrosine-protein kinase JAK2 | / | 0.447 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.447 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.447 | |
| 4jvb | 1M0 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.447 | |
| 4o7u | THF | Thymidylate synthase | / | 0.447 | |
| 4pds | ANP | Serine/threonine-protein kinase RAD53 | 2.7.12.1 | 0.447 | |
| 4ubv | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.447 | |
| 5br4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.447 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1mxt | FAE | Cholesterol oxidase | 1.1.3.6 | 0.446 | |
| 1phh | FAD | p-hydroxybenzoate hydroxylase | / | 0.446 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.446 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 1tvr | TB9 | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 1wwk | NAD | 307aa long hypothetical phosphoglycerate dehydrogenase | / | 0.446 | |
| 2bi4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.446 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.446 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.446 | |
| 2zyn | BCD | Periplasmic binding protein | / | 0.446 | |
| 3c9t | TPS | Thiamine-monophosphate kinase | / | 0.446 | |
| 3da2 | 4MD | Carbonic anhydrase 13 | 4.2.1.1 | 0.446 | |
| 3p3e | 3P3 | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.446 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.446 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.446 | |
| 3tm4 | SAM | Uncharacterized protein | / | 0.446 | |
| 3ute | FAD | UDP-galactopyranose mutase | / | 0.446 | |
| 3v2u | ATP | Protein GAL3 | / | 0.446 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.446 | |
| 4z5w | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.446 | |
| 1dna | CB3 | Thymidylate synthase | / | 0.445 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 1oho | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.445 | |
| 1ppj | ANY | Cytochrome b | / | 0.445 | |
| 1yi3 | LY2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 2fja | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.445 | |
| 2jj2 | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.445 | |
| 2kce | D16 | Thymidylate synthase | / | 0.445 | |
| 2rf2 | MRX | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
| 3ac2 | KSE | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.445 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.445 | |
| 3b9l | AZZ | Serum albumin | / | 0.445 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.445 | |
| 3mqe | 416 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.445 | |
| 3qlh | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.445 | |
| 3vjh | J35 | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.445 | |
| 4em9 | TCE | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 4f9m | FCM | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 4grb | 0XG | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.445 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.445 | |
| 4nmj | NAP | Aldehyde dehydrogenase | / | 0.445 | |
| 5cp8 | TCU | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 5e8y | STU | TGF-beta receptor type-2 | 2.7.11.30 | 0.445 | |
| 5hsa | FAS | Alcohol oxidase 1 | 1.1.3.13 | 0.445 | |
| 1a27 | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.444 | |
| 1qzf | CB3 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.444 | |
| 1w2x | RCP | Acetyl-CoA carboxylase | / | 0.444 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.444 | |
| 2gtm | LID | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 2oby | NAP | Quinone oxidoreductase PIG3 | 1 | 0.444 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 2xy9 | 3ES | Angiotensin-converting enzyme | 3.2.1 | 0.444 | |
| 2yek | EAM | Bromodomain-containing protein 2 | / | 0.444 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.444 | |
| 3e92 | G6A | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3gxo | MQA | Mitomycin biosynthesis 6-O-methyltransferase | / | 0.444 | |
| 3kp4 | MII | Transcriptional regulator TcaR | / | 0.444 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 3qiz | QI2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.444 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.444 | |
| 3zhv | TDW | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.444 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 4isk | 1JY | Thymidylate synthase | / | 0.444 | |
| 4xld | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 4xwt | U5P | Ribonuclease J | / | 0.444 | |
| 7cat | NDP | Catalase | 1.11.1.6 | 0.444 | |
| 1ewy | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.443 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.443 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.443 | |
| 1i7i | AZ2 | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.443 | |
| 1kzu | RG1 | Light-harvesting protein B-800/850 alpha chain | / | 0.443 | |
| 1kzu | RG1 | Light-harvesting protein B-800/850 beta chain | / | 0.443 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.443 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.443 | |
| 1s0x | C3S | Nuclear receptor ROR-alpha | / | 0.443 | |
| 2flh | ZEA | Cytokinin-specific binding protein | / | 0.443 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.443 | |
| 2j4z | 626 | Aurora kinase A | 2.7.11.1 | 0.443 | |
| 2m56 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 2vtd | LKM | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.443 | |
| 2xj2 | 985 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.443 | |
| 2yfe | YFE | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 2yg3 | FAD | Putrescine oxidase | / | 0.443 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.443 | |
| 3bej | MUF | Bile acid receptor | / | 0.443 | |
| 3cz0 | 9OD | Pheromone-binding protein ASP1 | / | 0.443 | |
| 3ipq | 965 | Oxysterols receptor LXR-alpha | / | 0.443 | |
| 3mje | NDP | AmphB | / | 0.443 | |
| 3nal | DBK | Calcium-transporting ATPase | / | 0.443 | |
| 3p7b | P7B | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.443 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.443 | |
| 4gi2 | NAP | Crotonyl-CoA carboxylase/reductase | / | 0.443 | |
| 4i2p | G73 | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.443 | |
| 4nmk | NAP | Aldehyde dehydrogenase | / | 0.443 | |
| 4o76 | 1M3 | Bromodomain-containing protein 4 | / | 0.443 | |
| 4zp0 | DXC | Multidrug transporter MdfA | / | 0.443 | |
| 5cms | APR | O-acetyl-ADP-ribose deacetylase | / | 0.443 | |
| 5d7p | OCZ | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.443 | |
| 1a5u | ATP | Pyruvate kinase PKM | 2.7.1.40 | 0.442 | |
| 1hpz | AAP | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.442 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.442 | |
| 1rdt | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 2gtn | LIE | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 2jds | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 2o65 | MYF | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.442 | |
| 2vcx | D26 | Hematopoietic prostaglandin D synthase | / | 0.442 | |
| 2xf3 | J01 | Uncharacterized protein | / | 0.442 | |
| 3akm | 11D | Fatty acid-binding protein, intestinal | / | 0.442 | |
| 3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.442 | |
| 3eku | CY9 | Actin-5C | / | 0.442 | |
| 3fr0 | AJB | Glucokinase | 2.7.1.2 | 0.442 | |
| 3i0s | RT7 | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 3i59 | N6R | CRP-like cAMP-activated global transcriptional regulator | / | 0.442 | |
| 3kxo | KXO | Hematopoietic prostaglandin D synthase | / | 0.442 | |
| 3l9m | L9M | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 3mdd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.442 | |
| 3sdk | P3N | Proteasome subunit beta type-5 | 3.4.25.1 | 0.442 | |
| 3sdk | P3N | Proteasome subunit beta type-6 | 3.4.25.1 | 0.442 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.442 | |
| 3u1y | 03I | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.442 | |
| 3zbn | COA | 3-ketoacyl-CoA thiolase-like protein | / | 0.442 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.442 | |
| 4c2z | 646 | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.442 | |
| 4cox | IMN | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.442 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.442 | |
| 4ji9 | 1M3 | Tyrosine-protein kinase JAK2 | / | 0.442 | |
| 4p13 | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.442 | |
| 4rv9 | SAH | D-mycarose 3-C-methyltransferase | / | 0.442 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.442 | |
| 5a3b | APR | SIR2 family protein | / | 0.442 | |
| 1eup | ASD | 6-deoxyerythronolide B hydroxylase | / | 0.441 | |
| 1olm | VTQ | SEC14-like protein 2 | / | 0.441 | |
| 1r0e | DFN | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.441 | |
| 1wxy | FRK | Adenosine deaminase | 3.5.4.4 | 0.441 | |
| 2ath | 3EA | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.441 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.441 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.441 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.441 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.441 | |
| 2uuv | FAD | Alkyldihydroxyacetonephosphate synthase | 2.5.1.26 | 0.441 | |
| 2vf0 | F89 | Thymidylate synthase | / | 0.441 | |
| 2yyl | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.441 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.441 | |
| 2zwv | SAH | Probable ribosomal RNA small subunit methyltransferase | / | 0.441 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.441 | |
| 3ezp | B3N | Histone deacetylase 8 | 3.5.1.98 | 0.441 | |
| 3imx | B84 | Glucokinase | 2.7.1.2 | 0.441 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.441 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.441 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.441 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.441 | |
| 4a95 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4eqw | COA | Coenzyme A disulfide reductase | / | 0.441 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.441 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.441 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.441 | |
| 4v12 | POG | MaoC like domain protein | / | 0.441 | |
| 4zs2 | FLU | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.441 | |
| 5ikq | JMS | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.441 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.441 | |
| 1dd6 | MCI | Metallo-beta-lactamase type 2 | / | 0.440 | |
| 1f4g | TP4 | Thymidylate synthase | / | 0.440 | |
| 1gqt | ACP | Ribokinase | / | 0.440 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.440 | |
| 1rt4 | UC1 | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.440 | |
| 1s6q | TPB | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.440 | |
| 1xpq | FAD | Polyamine oxidase FMS1 | / | 0.440 | |
| 1y6o | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.440 | |
| 1ysx | 4EB | Serum albumin | / | 0.440 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.440 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.440 | |
| 2yg5 | FAD | Putrescine oxidase | / | 0.440 | |
| 3cjg | KIM | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.440 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3ffi | 3OB | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.440 | |
| 3gyi | FAD | Cholesterol oxidase | 1.1.3.6 | 0.440 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.440 | |
| 3hll | I45 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3ju8 | NAD | N-succinylglutamate 5-semialdehyde dehydrogenase | 1.2.1.71 | 0.440 | |
| 3juq | AKD | Phenazine biosynthesis protein A/B | / | 0.440 | |
| 3meg | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 3nwl | NDP | Catalase | 1.11.1.6 | 0.440 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.440 | |
| 3ts4 | EEG | Macrophage metalloelastase | 3.4.24.65 | 0.440 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.440 | |
| 3zhq | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.440 | |
| 3zk5 | Z18 | Cytochrome P450 monooxygenase PikC | / | 0.440 | |
| 4b7x | NAP | Probable oxidoreductase | / | 0.440 | |
| 4kko | 1RE | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.440 | |
| 4z9g | 1Q5 | Corticotropin-releasing factor receptor 1 | / | 0.440 |