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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3t37FADPyridoxine 4-oxidase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3t37FADPyridoxine 4-oxidase/1.000
1gaqFADFerredoxin/0.508
4bfvZVVPantothenate kinase2.7.1.330.501
4xbfFADLysine-specific histone demethylase 1A10.496
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.495
3w5uFADFerredoxin/0.493
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.492
4bfxZVXPantothenate kinase2.7.1.330.491
3pe2E1BCasein kinase II subunit alpha2.7.11.10.490
5dozNDPJamJ/0.490
3ha5SFGHydroxymycolate synthase MmaA42.1.10.489
1g63FMNEpidermin decarboxylase4.1.10.487
2fgkATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.487
2ed3SAHDiphthine synthase/0.486
3h3r14HCollagen type IV alpha-3-binding protein/0.486
4bfwZVWPantothenate kinase2.7.1.330.486
2emuSAHDiphthine synthase/0.484
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.484
2dshSAHDiphthine synthase/0.482
3b03VNRIsopentenyl-diphosphate delta-isomerase/0.482
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.481
3pqbVGPPutative oxidoreductase/0.481
1opmIYGPeptidyl-glycine alpha-amidating monooxygenase1.14.17.30.480
1dkfBMSRetinoic acid receptor alpha/0.479
3in6FMNUncharacterized protein/0.479
1f20FADNitric oxide synthase, brain1.14.13.390.478
2ejzSAHDiphthine synthase/0.478
1fmlRTLRetinol dehydratase/0.477
1t9gFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.477
3d2pCOAAmino-acid acetyltransferase/0.477
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.477
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.476
3fp0FP015-O-acetyltransferase/0.476
3wagTYDGlycosyltransferase/0.476
4dpuAGSMevalonate diphosphate decarboxylase/0.476
3c3xNAPEugenol synthase 11.1.1.3180.475
1hfqMOTDihydrofolate reductase1.5.1.30.474
2eglSAHDiphthine synthase/0.474
2p6kSAHDiphthine synthase/0.474
3eksCY9Actin-5C/0.474
3wleNAD(R)-specific carbonyl reductase/0.474
4af6FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.474
4du82P0Mevalonate diphosphate decarboxylase/0.474
1c3x8IGPurine nucleoside phosphorylase2.4.2.10.473
2eleSAHDiphthine synthase/0.473
2gjnFMNNitronate monooxygenase1.13.12.160.473
2vcxD26Hematopoietic prostaglandin D synthase/0.473
2z4sADPChromosomal replication initiator protein DnaA/0.473
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.473
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.473
3ox34X4Ribosyldihydronicotinamide dehydrogenase [quinone]/0.473
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.473
4i0t1B6Tyrosine-protein kinase SYK2.7.10.20.473
1pg3PRXAcetyl-coenzyme A synthetase/0.472
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.472
2p6iSAHDiphthine synthase/0.472
2pk3A2RGDP-6-deoxy-D-mannose reductase/0.472
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.472
3nglNAPBifunctional protein FolD/0.472
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.472
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.471
2a1tFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.470
3biz61EWee1-like protein kinase2.7.10.20.470
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.470
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.470
3o3jBB4Peptide deformylase 1B, chloroplastic/mitochondrial3.5.1.880.470
3r7cFADFAD-linked sulfhydryl oxidase ALR1.8.3.20.470
3sl8JN7cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.470
3udk095Beta-secretase 13.4.23.460.470
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.469
1vbiNADMalate/L-lactate dehydrogenase family protein/0.469
2x06NADL-sulfolactate dehydrogenase/0.469
3bfb9ODPheromone-binding protein ASP1/0.469
3ekuCY9Actin-5C/0.469
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.469
2bu9HFVIsopenicillin N synthase1.21.3.10.468
2h94FADLysine-specific histone demethylase 1A10.468
3ox1695Ribosyldihydronicotinamide dehydrogenase [quinone]/0.468
4bftZVTPantothenate kinase2.7.1.330.468
1ju2FAD(R)-mandelonitrile lyase 24.1.2.100.467
1pd9CO4Dihydrofolate reductase1.5.1.30.467
2eniSAHDiphthine synthase/0.467
2xvw9NRSerum albumin/0.467
4eepFMNPhototropin-22.7.11.10.467
4pl0ANPMicrocin-J25 export ATP-binding/permease protein McjD/0.467
4yaoFMNNADPH--cytochrome P450 reductase/0.467
5f54TMPSingle-stranded-DNA-specific exonuclease/0.467
1zx1CB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.466
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.466
2vqbNAPPutative flavin-containing monooxygenase/0.466
2whqHI6Acetylcholinesterase3.1.1.70.466
1pq944BOxysterols receptor LXR-beta/0.465
2pb4SAHDiphthine synthase/0.465
2vd0D27Hematopoietic prostaglandin D synthase/0.465
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.465
4bfsZVSPantothenate kinase2.7.1.330.465
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.465
4hs4FMNChromate reductase/0.465
4iz02BIGenome polyprotein2.7.7.480.465
4oztP1AEcdysone receptor, putative/0.465
2e16SAHDiphthine synthase/0.464
2e8sSAHDiphthine synthase/0.464
2gvdFKPAdenylate cyclase type 2/0.464
2gvdFKPAdenylate cyclase type 5/0.464
2pb6SAHDiphthine synthase/0.464
2znq401Peroxisome proliferator-activated receptor delta/0.464
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.464
4hy6FJ1Heat shock protein HSP 90-alpha/0.464
2e08SAHDiphthine synthase/0.463
2g1r3IGRenin3.4.23.150.463
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.463
3mknDNBPyrimidine-specific ribonucleoside hydrolase RihB/0.463
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.463
3ukoNADAlcohol dehydrogenase class-3/0.463
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.463
4n82FMNRibonucleotide reductase (NrdI family protein), putative/0.463
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.462
1w0kADPATP synthase subunit alpha, mitochondrial/0.462
1w0kADPATP synthase subunit beta, mitochondrial3.6.3.140.462
3lpkZ76Beta-secretase 13.4.23.460.462
3nhkVAPRibosyldihydronicotinamide dehydrogenase [quinone]/0.462
4irnFADAnaB/0.462
4nieNBHNuclear receptor ROR-gamma/0.462
5c1mCLRMu-type opioid receptor/0.462
1b2lNDCAlcohol dehydrogenase1.1.1.10.461
1j0b5PAPutative 1-aminocyclopropane-1-carboxylate deaminase3.5.99.70.461
1me6IVSPlasmepsin-23.4.23.390.461
2bpoFADNADPH--cytochrome P450 reductase/0.461
2e8hSAHDiphthine synthase/0.461
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.461
2xvv9DNSerum albumin/0.461
2zrvFNRIsopentenyl-diphosphate delta-isomerase/0.461
3ohh3HHBeta-secretase 13.4.23.460.461
4cavMYAGlycylpeptide N-tetradecanoyltransferase2.3.1.970.461
4jlm1NNDeoxycytidine kinase2.7.1.740.461
4twnB96Ephrin type-A receptor 32.7.10.10.461
2xc3RT8Steroid C26-monooxygenase1.14.13.1410.460
2z7hGG3Geranylgeranyl pyrophosphate synthase/0.460
2ztsADPUncharacterized protein/0.460
3f883HTGlycogen synthase kinase-3 beta2.7.11.260.460
3vf60H6Glucokinase2.7.1.20.460
3vt8YI3Vitamin D3 receptor/0.460
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.460
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.460
4rquNADAlcohol dehydrogenase class-P/0.460
1h60STRPentaerythritol tetranitrate reductase/0.459
1xddAAYIntegrin alpha-L/0.459
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.459
2c29NAPDihydroflavonol 4-reductase/0.459
2ejkSAHDiphthine synthase/0.459
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.459
3h3sH15Collagen type IV alpha-3-binding protein/0.459
3jusBCDLanosterol 14-alpha demethylase1.14.13.700.459
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
3p2oNADBifunctional protein FolD/0.459
4fse0VABeta-secretase 13.4.23.460.459
5c3zACPRibokinase/0.459
1m9m6NINitric oxide synthase, endothelial1.14.13.390.458
2g226IGRenin3.4.23.150.458
2gpjFADSiderophore-interacting protein/0.458
2owvSAHDiphthine synthase/0.458
2pixDHTAndrogen receptor/0.458
2xveFADPutative flavin-containing monooxygenase/0.458
2y6fM9FIsopenicillin N synthase1.21.3.10.458
3dh7FMNIsopentenyl-diphosphate delta-isomerase/0.458
3g0yP9A3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.458
3qi4IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.458
3rpeFADPutative modulator of drug activity/0.458
4eb7PLPCysteine desulfurase IscS 2/0.458
4qaiFMNNADPH dehydrogenase/0.458
1amoFADNADPH--cytochrome P450 reductase/0.457
1mvsDTMDihydrofolate reductase1.5.1.30.457
1puaCOAHAT A1/0.457
1r2jFADFkbI/0.457
1rsgFADPolyamine oxidase FMS1/0.457
1z4uPH9Polyprotein/0.457
2dekSAHDiphthine synthase/0.457
2iko7IGRenin3.4.23.150.457
2p6lSAHDiphthine synthase/0.457
2qbuSAHPrecorrin-2 methyltransferase/0.457
2rlcCHDCholoylglycine hydrolase3.5.1.240.457
2rqfJH3Hemolymph juvenile hormone binding protein/0.457
2zrzFNRIsopentenyl-diphosphate delta-isomerase/0.457
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
3hu1AGSTransitional endoplasmic reticulum ATPase3.6.4.60.457
3nhfVVVRibosyldihydronicotinamide dehydrogenase [quinone]/0.457
3qofGDPAtlastin-13.6.50.457
3sl2ATPSensor histidine kinase WalK/0.457
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.457
3upkUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.457
4ih71ERGenome polyprotein2.7.7.480.457
4j6dTESCytochrome P450 monooxygenase/0.457
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.456
1tllFADNitric oxide synthase, brain1.14.13.390.456
1vceSAHDiphthine synthase/0.456
2owfSAHDiphthine synthase/0.456
2owuSAHDiphthine synthase/0.456
2yhuWHFPteridine reductase/0.456
3ha7B32Hydroxymycolate synthase MmaA42.1.10.456
3pmy41LEndothiapepsin3.4.23.220.456
3rdqDTBStreptavidin/0.456
3vkjFNRIsopentenyl-diphosphate delta-isomerase/0.456
3vt7VDXVitamin D3 receptor/0.456
4f32N323-oxoacyl-[acyl-carrier-protein] synthase 2/0.456
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.456
4ips1G4Mycocyclosin synthase1.14.21.90.456
4qzuRTLRetinol-binding protein 2/0.456
4uyf73BBromodomain-containing protein 2/0.456
1o97FADElectron transfer flavoprotein subunit alpha/0.455
1wliFMNFMN-binding protein/0.455
2dv5SAHDiphthine synthase/0.455
2dw4FADLysine-specific histone demethylase 1A10.455
2e07SAHDiphthine synthase/0.455
2g247IGRenin3.4.23.150.455
2il2LIXRenin3.4.23.150.455
2pchSAHDiphthine synthase/0.455
3ig6438Urokinase-type plasminogen activator3.4.21.730.455
3ivgFG5Pantothenate synthetase6.3.2.10.455
3ohf3HFBeta-secretase 13.4.23.460.455
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.455
4b4vL34Bifunctional protein FolD/0.455
4zzjCNANAD-dependent protein deacetylase sirtuin-13.5.10.455
2abbFMNPentaerythritol tetranitrate reductase/0.454
2aqbTL63-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.454
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.454
2ehlSAHDiphthine synthase/0.454
2f2sCOAAcetyl-CoA acetyltransferase, mitochondrial2.3.1.90.454
2g1s4IGRenin3.4.23.150.454
2pciSAHDiphthine synthase/0.454
2ywlFADThioredoxin reductase related protein/0.454
2z6rSAHDiphthine synthase/0.454
3dd125DGlycogen phosphorylase, liver form2.4.1.10.454
3fznD7KBenzoylformate decarboxylase4.1.1.70.454
3jv7NADSecondary alcohol dehydrogenase/0.454
3k5gBJCBeta-secretase 13.4.23.460.454
3ox4NADAlcohol dehydrogenase 21.1.1.10.454
3tneRITCandidapepsin-13.4.23.240.454
3tzaTZGGlutamate receptor 2/0.454
4bfuZVUPantothenate kinase2.7.1.330.454
4du6GTPGTP cyclohydrolase 1/0.454
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.454
4yd7F5NEndothiapepsin3.4.23.220.454
5ah5LSSLeucine--tRNA ligase/0.454
5akk1P8Bifunctional epoxide hydrolase 23.1.3.760.454
1yvfPH7Polyprotein/0.453
2eh4SAHDiphthine synthase/0.453
2ifaFMNUncharacterized protein/0.453
2ol4JPNEnoyl-ACP reductase/0.453
2p2bPRXAcetyl-coenzyme A synthetase/0.453
2webPP4Penicillopepsin-13.4.23.200.453
3b28B2XHeat shock protein HSP 90-alpha/0.453
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.453
3cic316Beta-secretase 13.4.23.460.453
3eigMTXDihydrofolate reductase1.5.1.30.453
3nmpPYVAbscisic acid receptor PYL2/0.453
3q2jCKIAminoglycoside 3'-phosphotransferase2.7.1.950.453
3rtnRTNBeta-secretase 13.4.23.460.453
3tifADPUncharacterized ABC transporter ATP-binding protein MJ0796/0.453
4djaFAD(6-4) photolyase/0.453
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.453
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.453
5a4vQUEGlutathione S-transferase F22.5.1.180.453
1lkeDOGBilin-binding protein/0.452
1tehNADAlcohol dehydrogenase class-31.1.1.10.452
2a94AP0L-lactate dehydrogenase1.1.1.270.452
2bktRPFRenin3.4.23.150.452
2fgjATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.452
2hkoFADLysine-specific histone demethylase 1A10.452
2pnjCHDFerrochelatase, mitochondrial4.99.1.10.452
2xlrFADPutative flavin-containing monooxygenase/0.452
3akm11DFatty acid-binding protein, intestinal/0.452
3clrFADElectron transfer flavoprotein subunit alpha/0.452
3hl0NADMaleylacetate reductase/0.452
3hu3AGSTransitional endoplasmic reticulum ATPase3.6.4.60.452
3s5wFADL-ornithine N(5)-monooxygenase/0.452
3uovFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.452
4a2aATPCell division protein FtsA/0.452
4ambDUDPutative glycosyl transferase/0.452
4b4w9L9Bifunctional protein FolD/0.452
4b63FADL-ornithine N(5)-monooxygenase/0.452
4df2FMNNADPH dehydrogenase/0.452
4kwi1TJReductase homolog/0.452
4mv8ACPBiotin carboxylase6.3.4.140.452
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.452
5dqrFAD7-hydroxymethyl chlorophyll a reductase, chloroplastic1.17.7.20.452
1k7fIAVTryptophan synthase alpha chain/0.451
1qsnCOAHAT A1/0.451
1x8lOXRRetinol dehydratase/0.451
2eldSAHDiphthine synthase/0.451
2rc6FADFerredoxin--NADP reductase/0.451
2vbdV10Isopenicillin N synthase1.21.3.10.451
2yj4ATPCopper-transporting ATPase/0.451
3af1GDPPantothenate kinase2.7.1.330.451
3qfcFADNADPH--cytochrome P450 reductase/0.451
4ri1ACOUDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase2.3.1.2020.451
4ldlXQCBeta-2 adrenergic receptor/0.451
1fy7COAHistone acetyltransferase ESA1/0.450
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.450
1pnvTYDdTDP-epi-vancosaminyltransferase2.4.1.3110.450
1uaeUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.450
2ahrNAPPyrroline-5-carboxylate reductase/0.450
2bf4FADNADPH--cytochrome P450 reductase/0.450
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.450
2eeqSAHDiphthine synthase/0.450
2ek4SAHDiphthine synthase/0.450
2g1n1IGRenin3.4.23.150.450
2givACOHistone acetyltransferase KAT8/0.450
2gv8NDPThiol-specific monooxygenase1.14.130.450
2i4qUA4Renin3.4.23.150.450
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.450
2r6gATPMaltose/maltodextrin import ATP-binding protein MalK/0.450
2v00V15Endothiapepsin3.4.23.220.450
2xlpNAPPutative flavin-containing monooxygenase/0.450
3akn11DFatty acid-binding protein, intestinal/0.450
3cid318Beta-secretase 13.4.23.460.450
3d5m4MSGenome polyprotein2.7.7.480.450
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.450
3oiaA31Camphor 5-monooxygenase1.14.15.10.450
3uxe465Ribosyldihydronicotinamide dehydrogenase [quinone]/0.450
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.450
4ejvLCLTranscriptional regulator TcaR/0.450
4ey6GNTAcetylcholinesterase3.1.1.70.450
4gt8ADPSensor protein VraS2.7.13.30.450
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.450
4n1gCEIObelin/0.450
1qiqACCIsopenicillin N synthase1.21.3.10.449
1rp7TZDPyruvate dehydrogenase E1 component1.2.4.10.449
1svmATPLarge T antigen3.6.40.449
2dsiSAHDiphthine synthase/0.449
2hw2RFPRifampin ADP-ribosyl transferase/0.449
2rc4ACOHistone acetyltransferase KAT6A/0.449
2zsdCOAPantothenate kinase2.7.1.330.449
3gyiFADCholesterol oxidase1.1.3.60.449
3jziJZLBiotin carboxylase6.3.4.140.449
3mhpFADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.449
3p62FMNPentaerythritol tetranitrate reductase/0.449
4ful0VUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4gqiM49Ribosyldihydronicotinamide dehydrogenase [quinone]/0.449
4i6h1C8Serine/threonine-protein kinase PLK22.7.11.210.449
4jazSTLPeroxisome proliferator-activated receptor gamma/0.449
1e7qNAPGDP-L-fucose synthase/0.448
1hncGDNGlutathione S-transferase Mu 22.5.1.180.448
1ndzFR5Adenosine deaminase3.5.4.40.448
1pjcNADAlanine dehydrogenase/0.448
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.448
1sdwIYTPeptidyl-glycine alpha-amidating monooxygenase1.14.17.30.448
1w7h3IPMitogen-activated protein kinase 14/0.448
1wn3HXCPhenylacetic acid degradation protein PaaI/0.448
1wngSAHDiphthine synthase/0.448
2dv7SAHDiphthine synthase/0.448
2huxSAHDiphthine synthase/0.448
2npfMOUElongation factor 2/0.448
2r8vACOAmino-acid acetyltransferase/0.448
2rl1UD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.448
2xaaNADSecondary alcohol dehydrogenase/0.448
2ym1FADPhenylacetone monooxygenase1.14.13.920.448
2yp0OVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.448
3clsFADElectron transfer flavoprotein subunit alpha/0.448
3g70A5TRenin3.4.23.150.448
3gdpFAD(R)-mandelonitrile lyase 24.1.2.100.448
3psyRB9Endothiapepsin3.4.23.220.448
3pwwROCEndothiapepsin3.4.23.220.448
3t4nADP5'-AMP-activated protein kinase subunit gamma/0.448
3up4FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.448
3vydVYDRenin3.4.23.150.448
4a2zVIQGlycylpeptide N-tetradecanoyltransferase/0.448
4b64FADL-ornithine N(5)-monooxygenase/0.448
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.448
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.448
4jbtASDCytochrome P450 monooxygenase/0.448
4l4xNDPAmphI/0.448
1i24UPGUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.447
1ikgREXD-alanyl-D-alanine carboxypeptidase3.4.16.40.447
1synF89Thymidylate synthase/0.447
1t4cCOAFormyl-CoA:oxalate CoA-transferase/0.447
1udyFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.447
1vbmYSATyrosine--tRNA ligase6.1.1.10.447
1zdwFLVPrenyltransferase/0.447
2egbSAHDiphthine synthase/0.447
2el3SAHDiphthine synthase/0.447
2emrSAHDiphthine synthase/0.447
2gdeSN3Prothrombin3.4.21.50.447
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.447
2iqgF2IBeta-secretase 13.4.23.460.447
2yk2YJXHeat shock protein HSP 90-alpha/0.447
3br3ETHTH-type transcriptional regulator QacR/0.447
3fpkFADFerredoxin-NADP reductase/0.447
3g8eIS1Nicotinamide phosphoribosyltransferase2.4.2.120.447
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.447
3mb601ICasein kinase II subunit alpha2.7.11.10.447
3oqkS52Renin3.4.23.150.447
3rdoBTNStreptavidin/0.447
3uylTYDProbable NDP-rhamnosyltransferase/0.447
3vn2TLSPeroxisome proliferator-activated receptor gamma/0.447
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.447
4fehFADDecaprenylphosphoryl-beta-D-ribose oxidase/0.447
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
4mlp2CXCryptochrome-2/0.447
4xg1LLPDiaminopimelate decarboxylase/0.447
1diaL24C-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.446
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.446
1oc1ASVIsopenicillin N synthase1.21.3.10.446
1u2yGOXPancreatic alpha-amylase/0.446
1xe55FEPlasmepsin-23.4.23.390.446
2e4nSAHDiphthine synthase/0.446
2ed5SAHDiphthine synthase/0.446
2fhlBNIAvidin-related protein 4/5/0.446
2znpK55Peroxisome proliferator-activated receptor delta/0.446
2zryFNRIsopentenyl-diphosphate delta-isomerase/0.446
3bsa1PDGenome polyprotein2.7.7.480.446
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3gb4D3MDdmC/0.446
3gnvXNZGenome polyprotein2.7.7.480.446
3i8p8403-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.446
3ojxFMNNADPH--cytochrome P450 reductase/0.446
3pm4F5NEndothiapepsin3.4.23.220.446
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.446
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.446
4u9yCOAAlpha-tubulin N-acetyltransferase 1/0.446
4wctFADFructosyl amine:oxygen oxidoreductase/0.446
4y380A9Endothiapepsin3.4.23.220.446
4y9rFADNADPH--cytochrome P450 reductase/0.446
4yt5H4MH(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338/0.446
1swtBTNStreptavidin/0.445
1szgFNSCytochrome b2, mitochondrial1.1.2.30.445
1w6hTITPlasmepsin-23.4.23.390.445
2abaSTRPentaerythritol tetranitrate reductase/0.445
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.445
2geuCOKPantothenate kinase2.7.1.330.445
2oyeIM8Prostaglandin G/H synthase 11.14.99.10.445
2q7vFADThioredoxin reductase/0.445
2vprTDCTetracycline repressor protein class H/0.445
2wecPP5Penicillopepsin-13.4.23.200.445
3a1l2CCCytochrome P450/0.445
3h3t16HCollagen type IV alpha-3-binding protein/0.445
3hkyIX6Genome polyprotein2.7.7.480.445
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.445
3mjeNDPAmphB/0.445
3r1rATPRibonucleoside-diphosphate reductase 1 subunit alpha1.17.4.10.445
4dc0NDPPutative ketoacyl reductase1.3.10.445
4e0hFADMitochondrial FAD-linked sulfhydryl oxidase ERV11.8.3.20.445
4h6pFMNChromate reductase/0.445
4jq4IMNAldo-keto reductase family 1 member C2/0.445
4y9uFADNADPH--cytochrome P450 reductase/0.445
5fbhTCRExtracellular calcium-sensing receptor/0.445
1e64FADFerredoxin--NADP reductase1.18.1.20.444
1fm4DXCMajor pollen allergen Bet v 1-L/0.444
1h69ARHNAD(P)H dehydrogenase [quinone] 11.6.5.20.444
1ja0FADNADPH--cytochrome P450 reductase/0.444
1nsgRADPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.444
1nsgRADSerine/threonine-protein kinase mTOR2.7.11.10.444
1nuqNXXNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.444
1vf2GTXGlutathione S-transferase 32.5.1.180.444
1x2hLPALipoate-protein ligase A6.3.1.200.444
2fxfACODiamine acetyltransferase 1/0.444
2gjlFMNNitronate monooxygenase1.13.12.160.444
2ou2ACOHistone acetyltransferase KAT5/0.444
2owgSAHDiphthine synthase/0.444
2pcaSAHDiphthine synthase/0.444
2rl2UD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.444
3bnkFMNFlavoredoxin/0.444
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.444
3dhcCYKN-acyl homoserine lactonase AiiA3.1.1.810.444
3hu2AGSTransitional endoplasmic reticulum ATPase3.6.4.60.444
3ivxFG6Pantothenate synthetase6.3.2.10.444
3kozZ97D-ornithine 4,5-aminomutase subunit beta/0.444
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.444
3s1dZIRCytokinin dehydrogenase 11.5.99.120.444
3uxhUXHRibosyldihydronicotinamide dehydrogenase [quinone]/0.444
3vqsJT1Genome polyprotein/0.444
3zbzOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.444
4do30LAFatty-acid amide hydrolase 13.5.1.990.444
4dvi2IWTankyrase-12.4.2.300.444
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.444
4ih61EPGenome polyprotein2.7.7.480.444
4ja1NGHStromelysin-13.4.24.170.444
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.443
1ppjANYCytochrome b/0.443
1qo8FADFumarate reductase flavoprotein subunit/0.443
1rfuADPPyridoxal kinase2.7.1.350.443
2bzsCB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.443
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.443
2dv4SAHDiphthine synthase/0.443
2e8rSAHDiphthine synthase/0.443
2eh5SAHDiphthine synthase/0.443
2fhnBNIAvidin-related protein 4/5/0.443
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.443
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.443
2xvfFADPutative flavin-containing monooxygenase/0.443
3ho2N323-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.443
3jzdNADMaleylacetate reductase/0.443
3mjrAC2Deoxycytidine kinase2.7.1.740.443
3own3OXRenin3.4.23.150.443
3qe2FMNNADPH--cytochrome P450 reductase/0.443
3ufl508Beta-secretase 13.4.23.460.443
3uleC69Actin-related protein 3/0.443
3zhrTPPMultifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.443
4b68FADL-ornithine N(5)-monooxygenase/0.443
4bfzZVZPantothenate kinase2.7.1.330.443
4c43FADFerredoxin--NADP reductase1.18.1.20.443
4e0iFADMitochondrial FAD-linked sulfhydryl oxidase ERV11.8.3.20.443
4eoi1ROCyclin-dependent kinase 22.7.11.220.443
1kapGLY_SER_ASN_SERSerralysin3.4.24.400.442
1knpFADL-aspartate oxidase1.4.3.160.442
1ogiFADFerredoxin--NADP reductase1.18.1.20.442
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.442
1qruATPGlutamine--tRNA ligase6.1.1.180.442
1rneC60Renin3.4.23.150.442
1u3r338Estrogen receptor beta/0.442
1vf3GDNGlutathione S-transferase 32.5.1.180.442
1x1bSAHC-20 methyltransferase/0.442
2dxwSAHDiphthine synthase/0.442
2he5NDPAldo-keto reductase family 1 member C211.1.10.442
2hj3FADFAD-linked sulfhydryl oxidase ERV1/0.442
2ikuLIYRenin3.4.23.150.442
2p5cSAHDiphthine synthase/0.442
2pirDHTAndrogen receptor/0.442
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3o73O73Ribosyldihydronicotinamide dehydrogenase [quinone]/0.442
3otbDGTProbable tRNA(His) guanylyltransferase2.7.7.790.442
3owuEQUSteroid Delta-isomerase5.3.3.10.442
3pn4BB2Peptide deformylase 1B, chloroplastic/mitochondrial3.5.1.880.442
3sf6FDAGlutaryl-CoA dehydrogenase/0.442
3uyk0CXProbable NDP-rhamnosyltransferase/0.442
3vyfVYFRenin3.4.23.150.442
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.442
4a81DXCMajor pollen allergen Bet v 1-A/0.442
4aa4QC0Mitogen-activated protein kinase 14/0.442
4b65NDPL-ornithine N(5)-monooxygenase/0.442
4d9eLCSD-cysteine desulfhydrase/0.442
4pd6URINucleoside permease/0.442
4rlh0WEEnoyl-[acyl-carrier-protein] reductase [NADH]/0.442
4wdfA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.442
4y7cFADNADPH--cytochrome P450 reductase/0.442
1bzfTMQDihydrofolate reductase1.5.1.30.441
1e2nRCAThymidine kinase/0.441
1ht5FL2Prostaglandin G/H synthase 11.14.99.10.441
1trgCB3Thymidylate synthase/0.441
1tv5A26Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.441
1umlFR4Adenosine deaminase3.5.4.40.441
1upw444Oxysterols receptor LXR-beta/0.441
1wuaAP8Actin, alpha skeletal muscle/0.441
2cftPLPPyridoxal phosphate phosphatase/0.441
2dxxSAHDiphthine synthase/0.441
2fjm073Tyrosine-protein phosphatase non-receptor type 13.1.3.480.441
2onmADPAldehyde dehydrogenase, mitochondrial1.2.1.30.441
2ovmAS0Progesterone receptor/0.441
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.441
2ym2FADPhenylacetone monooxygenase1.14.13.920.441
3e5aVX6Aurora kinase A2.7.11.10.441
3fskRO6Mitogen-activated protein kinase 14/0.441
3hk1B64Fatty acid-binding protein, adipocyte/0.441
3ielU5PRibonuclease TTHA02523.10.441
3oev3OEProteasome subunit beta type-53.4.25.10.441
3oev3OEProteasome subunit beta type-63.4.25.10.441
3qpnPFKcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.441
4af7FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.441
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.441
4bmpFMNProtein NrdI/0.441
4jzr4JREgl nine homolog 1/0.441
4y3qF02Endothiapepsin3.4.23.220.441
4yekTHMThymidine phosphorylase/0.441
4yqfGDPSeptin-9/0.441
5dbfNDPIridoid synthase1.3.1.990.441
5dp2NAPCurF/0.441
1a4iNDPC-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.440
1cqp803Integrin alpha-L/0.440
1d3dBZTProthrombin3.4.21.50.440
1dx6GNTAcetylcholinesterase3.1.1.70.440
1dxoFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.440
1qtiGNTAcetylcholinesterase3.1.1.70.440
1t2cNAIL-lactate dehydrogenase1.1.1.270.440
1ws1BB2Peptide deformylase 1/0.440
2cjfRP43-dehydroquinate dehydratase4.2.1.100.440
2e7rSAHDiphthine synthase/0.440
2pckSAHDiphthine synthase/0.440
2po7CHDFerrochelatase, mitochondrial4.99.1.10.440
2qmzLDPRibosyldihydronicotinamide dehydrogenase [quinone]/0.440
2y0mACOHistone acetyltransferase KAT8/0.440
3adaNADSubunit alpha of sarocosine oxidase/0.440
3jzfJZKBiotin carboxylase6.3.4.140.440
3mb714ICasein kinase II subunit alpha2.7.11.10.440
3nhwZXZRibosyldihydronicotinamide dehydrogenase [quinone]/0.440
3oqfS51Renin3.4.23.150.440
3vucHHERenin3.4.23.150.440
4a862ANMajor pollen allergen Bet v 1-A/0.440
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.440
4at0FADPossible succinate dehydrogenase/0.440
4bb3KKAIsopenicillin N synthase1.21.3.10.440
4dymIYZActivin receptor type-12.7.11.300.440
4emtC2EStimulator of interferon genes protein/0.440
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.440
4y7cFMNNADPH--cytochrome P450 reductase/0.440
5fd8A5APutative carboxypeptidase yocD/0.440
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.440
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.440
5kgpACOPredicted acetyltransferase/0.440