sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3swc | SAH | Histone-lysine N-methyltransferase EHMT1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3swc | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 1.000 | |
| 2rfi | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 0.629 | |
| 2o8j | SAH | Histone-lysine N-methyltransferase EHMT2 | / | 0.624 | |
| 5jin | SAM | Histone-lysine N-methyltransferase EHMT2 | / | 0.611 | |
| 3fpd | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 0.605 | |
| 3mo0 | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 0.600 | |
| 3hna | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 0.584 | |
| 5jhn | SAM | Histone-lysine N-methyltransferase EHMT2 | / | 0.572 | |
| 5jj0 | SAM | Histone-lysine N-methyltransferase EHMT2 | / | 0.564 | |
| 2igq | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 0.542 | |
| 4ype | SAM | Histone-lysine N-methyltransferase ASH1L | 2.1.1.43 | 0.534 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.527 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.520 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.514 | |
| 5hq8 | SAH | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.507 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.501 | |
| 3kmt | SAH | Histone H3K27 methylase | / | 0.501 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.500 | |
| 4l7h | 1W1 | Beta-secretase 1 | 3.4.23.46 | 0.500 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.498 | |
| 3k1w | BFX | Renin | 3.4.23.15 | 0.498 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.497 | |
| 1mu6 | CDA | Prothrombin | 3.4.21.5 | 0.496 | |
| 1q23 | FUA | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.495 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.495 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.494 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.493 | |
| 2fs4 | PZ1 | Renin | 3.4.23.15 | 0.493 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.492 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.492 | |
| 3m53 | SAH | Histone-lysine N-methyltransferase SETD7 | 2.1.1.43 | 0.492 | |
| 3sxj | SAM | Putative methyltransferase | / | 0.492 | |
| 4b1e | 6T6 | Beta-secretase 1 | 3.4.23.46 | 0.492 | |
| 4h3i | 10V | Beta-secretase 1 | 3.4.23.46 | 0.492 | |
| 1mmk | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.491 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.489 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.488 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.488 | |
| 5czy | SAM | Eukaryotic huntingtin interacting protein B | / | 0.488 | |
| 3oad | LPO | Renin | 3.4.23.15 | 0.487 | |
| 3qwp | SAM | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.487 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.487 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.486 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.486 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.485 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.484 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.484 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.484 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.484 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.484 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.483 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.483 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.483 | |
| 4i1c | 1BE | Beta-secretase 1 | 3.4.23.46 | 0.483 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.483 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.482 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.482 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.482 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.481 | |
| 2nr4 | FMN | Conserved protein | / | 0.481 | |
| 2x0f | TRH | WsaF | / | 0.481 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.481 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.481 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.481 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.481 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.480 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.480 | |
| 1sb1 | 165 | Prothrombin | 3.4.21.5 | 0.480 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.480 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.480 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.479 | |
| 5cho | FAD | Flavin reductase | / | 0.479 | |
| 5ex0 | SAH | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.479 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.478 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.478 | |
| 1fap | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.477 | |
| 1fap | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.477 | |
| 1w76 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.477 | |
| 2a2c | ADP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.477 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.477 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.477 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.477 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.477 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.477 | |
| 4nv1 | 4TG | Formyl transferase | / | 0.477 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.476 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.476 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.476 | |
| 4acx | S8Z | Beta-secretase 1 | 3.4.23.46 | 0.476 | |
| 4b70 | WM9 | Beta-secretase 1 | 3.4.23.46 | 0.476 | |
| 4dyp | 0MS | Nucleoprotein | / | 0.476 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.476 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.474 | |
| 1ypk | CCR | Prothrombin | 3.4.21.5 | 0.474 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.474 | |
| 2v3h | I25 | Prothrombin | 3.4.21.5 | 0.474 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.474 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.474 | |
| 1g60 | SAM | Modification methylase MboII | 2.1.1.72 | 0.473 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.473 | |
| 1ypg | UIR | Prothrombin | 3.4.21.5 | 0.473 | |
| 2ejz | SAH | Diphthine synthase | / | 0.473 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 3n19 | FNR | Xenobiotic reductase | / | 0.473 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.472 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.472 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.472 | |
| 3cbp | SFG | Histone-lysine N-methyltransferase SETD7 | 2.1.1.43 | 0.472 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.472 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.472 | |
| 4brd | ANP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.472 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.471 | |
| 1xds | DRA | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.471 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.471 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.471 | |
| 3nub | UD0 | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.471 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.471 | |
| 4h3g | 10Q | Beta-secretase 1 | 3.4.23.46 | 0.471 | |
| 1n95 | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.470 | |
| 1n95 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.470 | |
| 1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.470 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 3g6z | A7T | Renin | 3.4.23.15 | 0.470 | |
| 3i7v | B4P | AP4A hydrolase | / | 0.470 | |
| 4nv1 | 0FX | Formyl transferase | / | 0.470 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.469 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.469 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.469 | |
| 2zff | 53U | Prothrombin | 3.4.21.5 | 0.469 | |
| 2zhq | 27U | Prothrombin | 3.4.21.5 | 0.469 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.469 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.469 | |
| 3nks | ACJ | Protoporphyrinogen oxidase | 1.3.3.4 | 0.469 | |
| 3oxf | SAH | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.469 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.469 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.469 | |
| 1ja1 | FMN | NADPH--cytochrome P450 reductase | / | 0.468 | |
| 1k4m | NAD | Nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.468 | |
| 2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.468 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.468 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.468 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.468 | |
| 2znk | 31U | Prothrombin | 3.4.21.5 | 0.468 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.468 | |
| 3v2u | ATP | Protein GAL3 | / | 0.468 | |
| 1d9i | 00P | Prothrombin | 3.4.21.5 | 0.467 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.467 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.467 | |
| 1v48 | HA1 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.467 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.467 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.467 | |
| 4b0q | GMF | Beta-secretase 1 | 3.4.23.46 | 0.467 | |
| 4h0v | NAD | Iota toxin component Ia | / | 0.467 | |
| 3vw7 | VPX | Proteinase-activated receptor 1 | / | 0.467 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.466 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.466 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
| 2h21 | SAM | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.466 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 3c27 | DKK | Prothrombin | 3.4.21.5 | 0.466 | |
| 3h2s | NDP | Putative NADH-flavin reductase | / | 0.466 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 3ufl | 508 | Beta-secretase 1 | 3.4.23.46 | 0.466 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.466 | |
| 3zks | WZV | Beta-secretase 2 | 3.4.23.45 | 0.466 | |
| 1amo | FMN | NADPH--cytochrome P450 reductase | / | 0.465 | |
| 1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 1e1q | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.465 | |
| 1e1q | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.465 | |
| 2jh0 | 701 | Prothrombin | 3.4.21.5 | 0.465 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.465 | |
| 2zhw | 12U | Prothrombin | 3.4.21.5 | 0.465 | |
| 3f6r | FMN | Flavodoxin | / | 0.465 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.465 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.465 | |
| 1c4u | IH1 | Prothrombin | 3.4.21.5 | 0.464 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.464 | |
| 1rz1 | NAD | Phenol 2-hydroxylase component B | / | 0.464 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.464 | |
| 3wv7 | ADP | Hmd co-occurring protein HcgE | / | 0.464 | |
| 4bmp | FMN | Protein NrdI | / | 0.464 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.463 | |
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 1xag | NAD | 3-dehydroquinate synthase | / | 0.463 | |
| 1zxn | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.463 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.463 | |
| 2v3o | I26 | Prothrombin | 3.4.21.5 | 0.463 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.463 | |
| 2zfq | 45U | Prothrombin | 3.4.21.5 | 0.463 | |
| 3hat | GLY_VAL_ARG_RNG | Prothrombin | 3.4.21.5 | 0.463 | |
| 3oag | LPQ | Renin | 3.4.23.15 | 0.463 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.463 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.462 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.462 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 2vet | UMP | Thymidylate synthase | / | 0.462 | |
| 2vq7 | NAP | Putative flavin-containing monooxygenase | / | 0.462 | |
| 2zfr | 46U | Prothrombin | 3.4.21.5 | 0.462 | |
| 2zi2 | 24U | Prothrombin | 3.4.21.5 | 0.462 | |
| 2zvb | SAH | Precorrin-3 C17-methyltransferase | / | 0.462 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.462 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 3n71 | SFG | Histone-lysine N-methyltransferase Smyd1 | / | 0.462 | |
| 3ru0 | SFG | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.462 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.462 | |
| 4f0e | 0RU | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.462 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.462 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.462 | |
| 1lvu | 9PP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.461 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.461 | |
| 2hld | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.461 | |
| 2hld | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.461 | |
| 2jh5 | 895 | Prothrombin | 3.4.21.5 | 0.461 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.461 | |
| 2zdv | 37U | Prothrombin | 3.4.21.5 | 0.461 | |
| 3g72 | A6T | Renin | 3.4.23.15 | 0.461 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.461 | |
| 3tlc | 7MD | Microcin C7 self-immunity protein MccF | / | 0.461 | |
| 3zia | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.461 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.461 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.461 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.461 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.460 | |
| 1qzz | SAM | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.460 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.460 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.460 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.460 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 2zfp | 19U | Prothrombin | 3.4.21.5 | 0.460 | |
| 3kkz | SAM | Uncharacterized protein | / | 0.460 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.460 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.460 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.460 | |
| 4b1c | 1B1 | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.460 | |
| 4ha5 | 13W | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 4xr9 | NAD | CalS8 | / | 0.460 | |
| 1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.459 | |
| 1u71 | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 2xje | U5P | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.459 | |
| 3dzi | RGT | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.459 | |
| 3int | GDU | UDP-galactopyranose mutase | 5.4.99.9 | 0.459 | |
| 3oee | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.459 | |
| 3oee | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.459 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.459 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.459 | |
| 4h1e | 10J | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 1afe | ALZ | Prothrombin | 3.4.21.5 | 0.458 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.458 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.458 | |
| 2g27 | 4LG | Renin | 3.4.23.15 | 0.458 | |
| 2jh6 | 894 | Prothrombin | 3.4.21.5 | 0.458 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 2z3n | PHE_ARG_TYR_LEU_GLY | Leucyl/phenylalanyl-tRNA--protein transferase | 2.3.2.6 | 0.458 | |
| 4b65 | NDP | L-ornithine N(5)-monooxygenase | / | 0.458 | |
| 4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.458 | |
| 4h3f | 10O | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 4j83 | SAM | Histone-lysine N-methyltransferase SETD7 | 2.1.1.43 | 0.458 | |
| 4ke1 | 1R6 | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 4lc7 | 1WP | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.457 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.457 | |
| 2cn0 | F25 | Prothrombin | 3.4.21.5 | 0.457 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.457 | |
| 2g26 | 3LG | Renin | 3.4.23.15 | 0.457 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.457 | |
| 2ym2 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.457 | |
| 2zg0 | 50U | Prothrombin | 3.4.21.5 | 0.457 | |
| 3r9f | GSU | MccE protein | / | 0.457 | |
| 3vye | VYE | Renin | 3.4.23.15 | 0.457 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.457 | |
| 4blr | UTP | NTPase P4 | / | 0.457 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.457 | |
| 4jpe | 1M7 | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.456 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1gvh | FAD | Flavohemoprotein | / | 0.456 | |
| 1pl1 | ABY | Glutathione S-transferase A1 | 2.5.1.18 | 0.456 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.456 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.456 | |
| 2bvs | 2CE | Prothrombin | 3.4.21.5 | 0.456 | |
| 2ckm | AA7 | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 2ex1 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.456 | |
| 2f99 | AKV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.456 | |
| 2pau | D5M | 5'-deoxynucleotidase YfbR | / | 0.456 | |
| 2xtk | AZM | Class III chitinase ChiA1 | / | 0.456 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.456 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.456 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.456 | |
| 3zmg | 6Z0 | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.456 | |
| 4aws | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.456 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.456 | |
| 1c4y | IH3 | Prothrombin | 3.4.21.5 | 0.455 | |
| 1e79 | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.455 | |
| 1e79 | ATP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.455 | |
| 1o2g | 696 | Prothrombin | 3.4.21.5 | 0.455 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.455 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.455 | |
| 1ypm | RA4 | Prothrombin | 3.4.21.5 | 0.455 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.455 | |
| 2oc9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.455 | |
| 3pdn | SFG | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.455 | |
| 3qiy | QI1 | Botulinum neurotoxin type A | 3.4.24.69 | 0.455 | |
| 3tg4 | SAM | N-lysine methyltransferase SMYD2 | / | 0.455 | |
| 4awt | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.455 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.455 | |
| 4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.455 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.455 | |
| 4fri | DWA | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 4h6k | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.455 | |
| 4x28 | FDA | Acyl-CoA dehydrogenase FadE26 | / | 0.455 | |
| 4x28 | FDA | Acyl-CoA dehydrogenase FadE27 | / | 0.455 | |
| 5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.454 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.454 | |
| 1pr4 | MTP | Purine nucleoside phosphorylase DeoD-type | / | 0.454 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.454 | |
| 1xh5 | R68 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.454 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 2cf9 | 348 | Prothrombin | 3.4.21.5 | 0.454 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.454 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.454 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.454 | |
| 2xlu | NA7 | Putative flavin-containing monooxygenase | / | 0.454 | |
| 2zgb | 21U | Prothrombin | 3.4.21.5 | 0.454 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 3qto | 10P | Prothrombin | 3.4.21.5 | 0.454 | |
| 4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4b5n | FMN | NAD(P)H:flavin oxidoreductase Sye4 | / | 0.454 | |
| 4djy | 0KR | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4dya | 0MF | Nucleoprotein | / | 0.454 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.454 | |
| 4glx | 0XS | DNA ligase | 6.5.1.2 | 0.454 | |
| 4jji | NAD | Alcohol dehydrogenase class-3 | / | 0.454 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 1n95 | FTH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.453 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.453 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.453 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.453 | |
| 3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.453 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.453 | |
| 3s7d | LEU_SER_LYS_LYS_MLZ | N-lysine methyltransferase SMYD2 | / | 0.453 | |
| 3w2f | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.453 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 4i13 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 4i4z | 2NE | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.453 | |
| 4qoe | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.453 | |
| 4y1b | NAP | AntE | / | 0.453 | |
| 4zvn | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.453 | |
| 1je1 | GMP | Purine nucleoside phosphorylase | / | 0.452 | |
| 1kw0 | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.452 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.452 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.452 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.452 | |
| 2gby | BRN | HTH-type transcriptional regulator QacR | / | 0.452 | |
| 2zda | 32U | Prothrombin | 3.4.21.5 | 0.452 | |
| 2zgx | 29U | Prothrombin | 3.4.21.5 | 0.452 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.452 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.452 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.452 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.452 | |
| 4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.452 | |
| 4bah | MEL | Prothrombin | 3.4.21.5 | 0.452 | |
| 4kou | C04 | Uncharacterized protein | / | 0.452 | |
| 4n82 | FMN | Ribonucleotide reductase (NrdI family protein), putative | / | 0.452 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.452 | |
| 4tnz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.452 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.452 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 1nl4 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.451 | |
| 1vhz | APR | ADP compounds hydrolase NudE | 3.6.1 | 0.451 | |
| 2b99 | RDL | Riboflavin synthase | 2.5.1.9 | 0.451 | |
| 2cle | F6F | Tryptophan synthase alpha chain | / | 0.451 | |
| 2fap | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.451 | |
| 2fap | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.451 | |
| 2pbw | DOQ | Glutamate receptor ionotropic, kainate 1 | / | 0.451 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.451 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 4da7 | AC2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.451 | |
| 1fw0 | KAI | Glutamate receptor 2 | / | 0.450 | |
| 1fxu | GU7 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 1nbi | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.450 | |
| 2uuj | 896 | Prothrombin | 3.4.21.5 | 0.450 | |
| 2v7q | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.450 | |
| 2v7q | ATP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.450 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.450 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.450 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.450 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.450 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.450 | |
| 4cf6 | CBD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 4eil | UMP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.450 | |
| 1h69 | ARH | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1nsg | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.449 | |
| 1nsg | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.449 | |
| 1til | ATP | Anti-sigma F factor | / | 0.449 | |
| 2bsx | NOS | Purine nucleoside phosphorylase | / | 0.449 | |
| 2cf8 | ESH | Prothrombin | 3.4.21.5 | 0.449 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.449 | |
| 2wnb | C5P | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 | 2.4.99.4 | 0.449 | |
| 2yac | 937 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.449 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.449 | |
| 3b6p | TMP | Three-prime repair exonuclease 1 | 3.1.11.2 | 0.449 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.449 | |
| 3hky | IX6 | Genome polyprotein | 2.7.7.48 | 0.449 | |
| 3reo | SAH | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.449 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3sfy | 3FY | Uncharacterized protein | / | 0.449 | |
| 3w3z | GTP | GTP-binding nuclear protein Ran | / | 0.449 | |
| 4d7e | FAD | Putative lysine-N-oxygenase | / | 0.449 | |
| 4dri | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.449 | |
| 4dri | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.449 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 4kw5 | 1W6 | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.449 | |
| 4tti | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.449 | |
| 4yfy | 0FX | VioF | / | 0.449 | |
| 1ae8 | AZL | Prothrombin | 3.4.21.5 | 0.448 | |
| 1c7o | PPG | Hemolysin | / | 0.448 | |
| 1fdu | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.448 | |
| 1gal | FAD | Glucose oxidase | 1.1.3.4 | 0.448 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.448 | |
| 1jdz | FMB | Purine nucleoside phosphorylase | / | 0.448 | |
| 1ni1 | 2C5 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.448 | |
| 1oyt | FSN | Prothrombin | 3.4.21.5 | 0.448 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.448 | |
| 1xkq | NDP | Uncharacterized protein | / | 0.448 | |
| 2cmf | F11 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.448 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.448 | |
| 2z3l | PHE_ARG_TYR_LEU_GLY | Leucyl/phenylalanyl-tRNA--protein transferase | 2.3.2.6 | 0.448 | |
| 3dhk | 23U | Prothrombin | 3.4.21.5 | 0.448 | |
| 3qgi | 33F | Genome polyprotein | 2.7.7.48 | 0.448 | |
| 3tfy | COA | N-alpha-acetyltransferase 50 | 2.3.1 | 0.448 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.448 | |
| 3vjl | W94 | Dipeptidyl peptidase 4 | / | 0.448 | |
| 3vsx | R32 | Renin | 3.4.23.15 | 0.448 | |
| 4djw | 0KP | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4flk | Y10 | Methionine aminopeptidase 1 | / | 0.448 | |
| 4hfp | 15U | Prothrombin | 3.4.21.5 | 0.448 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4jxr | ACO | Acetyltransferase | / | 0.448 | |
| 1lpc | CMP | Antiviral protein DAP-30 | 3.2.2.22 | 0.447 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 1vhn | FMN | tRNA-dihydrouridine synthase | / | 0.447 | |
| 1yry | MSG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.447 | |
| 2pj4 | 414 | Carboxypeptidase B | / | 0.447 | |
| 2poq | ISD | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase | 1.3.1.20 | 0.447 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.447 | |
| 2vat | COA | Acetyl-CoA--deacetylcephalosporin C acetyltransferase | 2.3.1.175 | 0.447 | |
| 2xei | ARK | Glutamate carboxypeptidase 2 | 3.4.17.21 | 0.447 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.447 | |
| 3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.447 | |
| 3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.447 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.447 | |
| 3r95 | ACO | MccE protein | / | 0.447 | |
| 3w0t | HPU | Lactoylglutathione lyase | 4.4.1.5 | 0.447 | |
| 4b00 | I6X | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 4g8j | THM | Uridine phosphorylase | / | 0.447 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.447 | |
| 4x7v | MIV | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.447 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.447 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1icq | OPD | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.446 | |
| 1j9z | FAD | NADPH--cytochrome P450 reductase | / | 0.446 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.446 | |
| 1tiq | COA | Spermidine/spermine N(1)-acetyltransferase | / | 0.446 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.446 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.446 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.446 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.446 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.446 | |
| 2v34 | CTN | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.446 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 2zc9 | 22U | Prothrombin | 3.4.21.5 | 0.446 | |
| 3eku | CY9 | Actin-5C | / | 0.446 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.446 | |
| 3rtn | RTN | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3t7s | SAM | Uncharacterized protein | / | 0.446 | |
| 3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.446 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.446 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.446 | |
| 4j1f | 1HL | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4lut | DCS | Alanine racemase | / | 0.446 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.446 | |
| 4mvc | CDC | Choline-phosphate cytidylyltransferase A | / | 0.446 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.446 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.446 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 1fdt | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.445 | |
| 1ra8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1rd7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.445 | |
| 2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.445 | |
| 2fxf | ACO | Diamine acetyltransferase 1 | / | 0.445 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.445 | |
| 2q15 | 3MR | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.445 | |
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 3eq0 | 2TS | Prothrombin | 3.4.21.5 | 0.445 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.445 | |
| 3hii | PNT | Amiloride-sensitive amine oxidase [copper-containing] | / | 0.445 | |
| 3ho2 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.445 | |
| 3p9k | SAH | Caffeic acid O-methyltransferase | / | 0.445 | |
| 3upy | FOM | Oxidoreductase, putative | / | 0.445 | |
| 3vkj | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.445 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.445 | |
| 4f7i | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.445 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 4l7j | 1W2 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4na4 | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.445 | |
| 4ynp | SAM | Histone-lysine N-methyltransferase ASH1L | 2.1.1.43 | 0.445 | |
| 5ej8 | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.445 | |
| 5kwv | ANP | Pantothenate synthetase | / | 0.445 | |
| 1mu8 | CDB | Prothrombin | 3.4.21.5 | 0.444 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.444 | |
| 2w6p | OA4 | Biotin carboxylase | 6.3.4.14 | 0.444 | |
| 2x1h | X1H | Prostaglandin reductase 3 | 1 | 0.444 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 2xvh | NAP | Putative flavin-containing monooxygenase | / | 0.444 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.444 | |
| 2yye | APC | Selenide, water dikinase | 2.7.9.3 | 0.444 | |
| 2zrz | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.444 | |
| 3b8x | G4M | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.444 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.444 | |
| 3i8p | 840 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.444 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.444 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 3vuc | HHE | Renin | 3.4.23.15 | 0.444 | |
| 4b05 | 32D | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4b64 | NAP | L-ornithine N(5)-monooxygenase | / | 0.444 | |
| 4b78 | KGG | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.444 | |
| 4x5h | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.444 | |
| 1dds | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.443 | |
| 1ra3 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.443 | |
| 1w0k | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.443 | |
| 1w0k | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.443 | |
| 1y7l | ASN_LEU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.443 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.443 | |
| 2a2d | ANP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.443 | |
| 2bkt | RPF | Renin | 3.4.23.15 | 0.443 | |
| 2e8q | SAH | Diphthine synthase | / | 0.443 | |
| 2iib | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.443 | |
| 2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.443 | |
| 2vf3 | GVS | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.443 | |
| 2xke | WI2 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.443 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2xys | SY9 | Soluble acetylcholine receptor | / | 0.443 | |
| 3d64 | NAD | Adenosylhomocysteinase | / | 0.443 | |
| 3e32 | ED2 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.443 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.443 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.443 | |
| 3ksq | Z96 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.443 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.443 | |
| 3sfh | 1DI | Histone deacetylase 8 | 3.5.1.98 | 0.443 | |
| 3uax | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.443 | |
| 3uay | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.443 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.443 | |
| 3zov | WZV | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.443 | |
| 4dl9 | NAD | S-(hydroxymethyl)glutathione dehydrogenase | / | 0.443 | |
| 4imf | SI3 | N-acetylneuraminate lyase | / | 0.443 | |
| 4ke0 | 1R8 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4mrt | COA | 4'-phosphopantetheinyl transferase sfp | 2.7.8 | 0.443 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.442 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 1gj4 | 132 | Prothrombin | 3.4.21.5 | 0.442 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1zrb | 062 | Prothrombin | 3.4.21.5 | 0.442 | |
| 2gfx | PMN | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.442 | |
| 2po3 | T4K | 4-dehydrase | / | 0.442 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3exo | 5MS | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3m2u | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.442 | |
| 3p17 | 99P | Prothrombin | 3.4.21.5 | 0.442 | |
| 3uko | NAD | Alcohol dehydrogenase class-3 | / | 0.442 | |
| 4b72 | 2FB | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4de2 | DN3 | Beta-lactamase | / | 0.442 | |
| 4ge9 | 0L0 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.442 | |
| 4j75 | TYM | Tryptophan--tRNA ligase | / | 0.442 | |
| 4jic | FMN | GTN Reductase | / | 0.442 | |
| 4nau | AGS | Phosphopantetheine adenylyltransferase | / | 0.442 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.442 | |
| 4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.442 | |
| 4utl | FNR | Xenobiotic reductase | / | 0.442 | |
| 4yp6 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.442 | |
| 1d4p | BPP | Prothrombin | 3.4.21.5 | 0.441 | |
| 1ni1 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.441 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.441 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 1t4c | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.441 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.441 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.441 | |
| 2y66 | N04 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.441 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.441 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3ojx | FAD | NADPH--cytochrome P450 reductase | / | 0.441 | |
| 3pn1 | IVH | DNA ligase | / | 0.441 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.441 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.441 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 4asu | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.441 | |
| 4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.441 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4hh4 | SAH | CcbJ | / | 0.441 | |
| 4j3m | AJ8 | Tankyrase-2 | 2.4.2.30 | 0.441 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.441 | |
| 4n3r | 2GU | Tankyrase-1 | 2.4.2.30 | 0.441 | |
| 5dp2 | NAP | CurF | / | 0.441 | |
| 5esd | TDP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.441 | |
| 1an5 | CB3 | Thymidylate synthase | / | 0.440 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.440 | |
| 1kw8 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.440 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.440 | |
| 1w7g | MIU | Prothrombin | 3.4.21.5 | 0.440 | |
| 2bqz | SAH | N-lysine methyltransferase KMT5A | / | 0.440 | |
| 2fzm | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.440 | |
| 2iu8 | UD1 | UDP-3-O-acylglucosamine N-acyltransferase | 2.3.1 | 0.440 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.440 | |
| 2v19 | FMN | Dodecin | / | 0.440 | |
| 2zrx | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.440 | |
| 3bgx | TMP | Thymidylate synthase | / | 0.440 | |
| 3biv | 11U | Prothrombin | 3.4.21.5 | 0.440 | |
| 3e4a | QIX | Insulin-degrading enzyme | 3.4.24.56 | 0.440 | |
| 3klb | FMN | Uncharacterized protein | / | 0.440 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.440 | |
| 4b1j | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.440 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.440 | |
| 4c3y | ANB | 3-ketosteroid dehydrogenase | / | 0.440 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.440 | |
| 4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.440 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.440 | |
| 4o30 | SAH | Probable Histone-lysine N-methyltransferase ATXR5 | 2.1.1.43 | 0.440 | |
| 4rxq | DUT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.440 | |
| 4tta | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.440 | |
| 4xoq | F42 | Coenzyme F420:L-glutamate ligase | / | 0.440 | |
| 4zzj | CNA | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.440 | |
| 5f59 | SAH | Histone-lysine N-methyltransferase 2C | 2.1.1.43 | 0.440 | |
| 5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.440 | |
| 7kme | ACE_0BN_CHG_PRR | Prothrombin | 3.4.21.5 | 0.440 |