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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3sfy3FYUncharacterized protein

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3sfy3FYUncharacterized protein/1.000
3q7fED2Uncharacterized protein/0.786
1sa5BMVProtein farnesyltransferase subunit beta2.5.1.580.638
1jcq739Protein farnesyltransferase subunit beta2.5.1.580.632
2r2lPB9Protein farnesyltransferase subunit beta2.5.1.580.624
3e33ED7Protein farnesyltransferase subunit beta2.5.1.580.619
1ld7U66Protein farnesyltransferase subunit beta2.5.1.580.618
1s63778Protein farnesyltransferase subunit beta2.5.1.580.613
3e30ED4Protein farnesyltransferase subunit beta2.5.1.580.604
1o1s1NHProtein farnesyltransferase subunit beta2.5.1.580.601
1n95FTHProtein farnesyltransferase subunit beta2.5.1.580.594
1ld8U49Protein farnesyltransferase subunit beta2.5.1.580.591
1sa4JANProtein farnesyltransferase subunit beta2.5.1.580.588
1mzcBNEProtein farnesyltransferase subunit beta2.5.1.580.585
2h6iCYS_VAL_LEU_SER_GERProtein farnesyltransferase subunit beta2.5.1.580.580
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.569
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.569
3ksqZ96Protein farnesyltransferase subunit beta2.5.1.580.542
2f0y3MNProtein farnesyltransferase subunit beta2.5.1.580.538
2iejS48Protein farnesyltransferase subunit beta2.5.1.580.524
3pz43PZProtein farnesyltransferase subunit beta2.5.1.580.509
4gtr7TRProtein farnesyltransferase subunit beta2.5.1.580.491
1o1t2NHProtein farnesyltransferase subunit beta2.5.1.580.483
3pz23PZGeranylgeranyl transferase type-2 subunit beta2.5.1.600.480
1n4sCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.463
3sfxJANUncharacterized protein/0.451
1ni1HFPProtein farnesyltransferase subunit beta2.5.1.580.446
4gtv7TRGeranylgeranyl transferase type-2 subunit beta2.5.1.600.441