sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3sfi | 3SF | HTH-type transcriptional regulator EthR |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3sfi | 3SF | HTH-type transcriptional regulator EthR | / | 1.000 | |
| 3q0v | LL4 | HTH-type transcriptional regulator EthR | / | 0.630 | |
| 3q0u | LL3 | HTH-type transcriptional regulator EthR | / | 0.622 | |
| 3o8g | O8G | HTH-type transcriptional regulator EthR | / | 0.615 | |
| 3o8h | O8H | HTH-type transcriptional regulator EthR | / | 0.609 | |
| 3tp0 | FO5 | HTH-type transcriptional regulator EthR | / | 0.607 | |
| 3g1m | RF3 | HTH-type transcriptional regulator EthR | / | 0.603 | |
| 2j3k | NAP | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.465 | |
| 3p6p | A6B | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 3p6m | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 3p6n | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 5dbg | NAD | Iridoid synthase | 1.3.1.99 | 0.454 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.452 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.448 | |
| 1re9 | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 4dw6 | 0MN | HTH-type transcriptional regulator EthR | / | 0.445 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 3p6o | ETG | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 3sgt | P09 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | / | 0.444 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.441 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.440 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
| 4e0i | FAD | Mitochondrial FAD-linked sulfhydryl oxidase ERV1 | 1.8.3.2 | 0.440 |