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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3sfeFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3sfeFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/1.000
4kx6FADFumarate reductase flavoprotein subunit1.3.5.40.547
4ytnFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.545
5c2tFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.543
5c3jFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.543
1kf6FADFumarate reductase flavoprotein subunit1.3.5.40.536
1knrFADL-aspartate oxidase1.4.3.160.469
1d4dFADFumarate reductase flavoprotein subunit1.3.5.40.461
1d4cFADFumarate reductase flavoprotein subunit1.3.5.40.451