sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3sbi | E90 | Carbonic anhydrase 2 | 4.2.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3sbi | E90 | Carbonic anhydrase 2 | 4.2.1.1 | 1.000 | |
| 3ffp | LC1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.871 | |
| 1oq5 | CEL | Carbonic anhydrase 2 | 4.2.1.1 | 0.862 | |
| 3s9t | E49 | Carbonic anhydrase 2 | 4.2.1.1 | 0.844 | |
| 4kni | E1E | Carbonic anhydrase 2 | 4.2.1.1 | 0.842 | |
| 3nb5 | R21 | Carbonic anhydrase 2 | 4.2.1.1 | 0.820 | |
| 3m2n | J74 | Carbonic anhydrase 2 | 4.2.1.1 | 0.809 | |
| 3s8x | E59 | Carbonic anhydrase 2 | 4.2.1.1 | 0.803 | |
| 2eu3 | FF3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.802 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.797 | |
| 3m98 | E02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.793 | |
| 3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.792 | |
| 4itp | 1GD | Carbonic anhydrase 2 | 4.2.1.1 | 0.788 | |
| 1g52 | F2B | Carbonic anhydrase 2 | 4.2.1.1 | 0.774 | |
| 3eft | 3BS | Carbonic anhydrase 2 | 4.2.1.1 | 0.774 | |
| 2pow | I7C | Carbonic anhydrase 2 | 4.2.1.1 | 0.762 | |
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.759 | |
| 3mmf | D9H | Carbonic anhydrase 2 | 4.2.1.1 | 0.759 | |
| 3mna | DWH | Carbonic anhydrase 2 | 4.2.1.1 | 0.759 | |
| 3f4x | KLT | Carbonic anhydrase 2 | 4.2.1.1 | 0.756 | |
| 3n0n | P9B | Carbonic anhydrase 2 | 4.2.1.1 | 0.756 | |
| 3m96 | E38 | Carbonic anhydrase 2 | 4.2.1.1 | 0.755 | |
| 3mhi | J90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.753 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.750 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.748 | |
| 3m40 | J45 | Carbonic anhydrase 2 | 4.2.1.1 | 0.741 | |
| 4knj | E1F | Carbonic anhydrase 2 | 4.2.1.1 | 0.739 | |
| 3sax | E50 | Carbonic anhydrase 2 | 4.2.1.1 | 0.737 | |
| 4m2v | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.736 | |
| 1g45 | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.735 | |
| 3b4f | TUO | Carbonic anhydrase 2 | 4.2.1.1 | 0.730 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.729 | |
| 1i90 | INM | Carbonic anhydrase 2 | 4.2.1.1 | 0.726 | |
| 3oys | OYS | Carbonic anhydrase 2 | 4.2.1.1 | 0.724 | |
| 1g1d | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.721 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.719 | |
| 4bf6 | X0Q | Carbonic anhydrase 2 | 4.2.1.1 | 0.719 | |
| 3mho | J43 | Carbonic anhydrase 2 | 4.2.1.1 | 0.717 | |
| 2weg | FBV | Carbonic anhydrase 2 | 4.2.1.1 | 0.716 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.715 | |
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.711 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.708 | |
| 3mzc | S6I | Carbonic anhydrase 2 | 4.2.1.1 | 0.706 | |
| 4iwz | 1GO | Carbonic anhydrase 2 | 4.2.1.1 | 0.706 | |
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.705 | |
| 1bnm | AL8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.704 | |
| 3t82 | SG4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.704 | |
| 4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 | 0.704 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.703 | |
| 2wej | FB2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.698 | |
| 3m5e | JDR | Carbonic anhydrase 2 | 4.2.1.1 | 0.697 | |
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.696 | |
| 4k13 | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.695 | |
| 4m2r | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.695 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.693 | |
| 3n3j | WWV | Carbonic anhydrase 2 | 4.2.1.1 | 0.693 | |
| 4kap | 1QV | Carbonic anhydrase 2 | 4.2.1.1 | 0.693 | |
| 3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.691 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.690 | |
| 3hku | TOR | Carbonic anhydrase 2 | 4.2.1.1 | 0.689 | |
| 3t84 | SG6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.687 | |
| 1cny | EG3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.686 | |
| 1g4j | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.686 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.686 | |
| 1if5 | FBT | Carbonic anhydrase 2 | 4.2.1.1 | 0.685 | |
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.684 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.684 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.681 | |
| 1cnw | EG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.679 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.679 | |
| 1cil | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.678 | |
| 3m2y | BE0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.677 | |
| 2weo | FBW | Carbonic anhydrase 2 | 4.2.1.1 | 0.676 | |
| 3m67 | E36 | Carbonic anhydrase 2 | 4.2.1.1 | 0.676 | |
| 1eou | SMS | Carbonic anhydrase 2 | 4.2.1.1 | 0.674 | |
| 1kwq | SG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.674 | |
| 1okn | STB | Carbonic anhydrase 2 | 4.2.1.1 | 0.673 | |
| 1if4 | FBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.671 | |
| 3daz | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.669 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.668 | |
| 3n4b | WWZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.667 | |
| 2h4n | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.666 | |
| 1bnv | AL7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.665 | |
| 1okl | MNS | Carbonic anhydrase 2 | 4.2.1.1 | 0.663 | |
| 3oy0 | OY0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.659 | |
| 1bn4 | AL9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.656 | |
| 1i8z | INL | Carbonic anhydrase 2 | 4.2.1.1 | 0.655 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.652 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.647 | |
| 3bet | CTF | Carbonic anhydrase 2 | 4.2.1.1 | 0.646 | |
| 3mhl | J71 | Carbonic anhydrase 2 | 4.2.1.1 | 0.646 | |
| 4mo8 | 2VQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.645 | |
| 1a42 | BZU | Carbonic anhydrase 2 | 4.2.1.1 | 0.644 | |
| 4pxx | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.641 | |
| 1okm | SAB | Carbonic anhydrase 2 | 4.2.1.1 | 0.640 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.638 | |
| 1i9n | IOA | Carbonic anhydrase 2 | 4.2.1.1 | 0.637 | |
| 1yda | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.637 | |
| 3l14 | I7B | Carbonic anhydrase 2 | 4.2.1.1 | 0.635 | |
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.632 | |
| 2wd2 | MS5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.632 | |
| 1bnt | AL2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.631 | |
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.629 | |
| 1bn1 | AL5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.628 | |
| 3sbh | E65 | Carbonic anhydrase 2 | 4.2.1.1 | 0.628 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.627 | |
| 1bn3 | AL6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.624 | |
| 1bnq | AL4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.622 | |
| 3ni5 | C1H | Carbonic anhydrase 2 | 4.2.1.1 | 0.621 | |
| 4kp8 | E1G | Carbonic anhydrase 12 | 4.2.1.1 | 0.621 | |
| 1bnw | TPD | Carbonic anhydrase 2 | 4.2.1.1 | 0.620 | |
| 1i9q | IOF | Carbonic anhydrase 2 | 4.2.1.1 | 0.620 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.620 | |
| 2x7u | WZA | Carbonic anhydrase 2 | 4.2.1.1 | 0.618 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.614 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.614 | |
| 3n2p | AYX | Carbonic anhydrase 2 | 4.2.1.1 | 0.612 | |
| 1g4o | BSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.610 | |
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 0.609 | |
| 1xpz | 4TZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.608 | |
| 3oyq | OYQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.607 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.599 | |
| 3mhc | ARZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.598 | |
| 4n16 | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.593 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.590 | |
| 4kp5 | E1F | Carbonic anhydrase 12 | 4.2.1.1 | 0.589 | |
| 4x5s | AZM | Carbonic anhydrase (Carbonate dehydratase) | / | 0.587 | |
| 3znc | BZ1 | Carbonic anhydrase 4 | 4.2.1.1 | 0.584 | |
| 3rz8 | RZ8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.579 | |
| 4lu3 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.578 | |
| 2q1q | OSP | Carbonic anhydrase 2 | 4.2.1.1 | 0.576 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.572 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.572 | |
| 4uov | AZM | Carbonate dehydratase | / | 0.572 | |
| 3p5l | IT5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.570 | |
| 3dcc | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.569 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.569 | |
| 3d8w | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.568 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.564 | |
| 3f7u | AG4 | Carbonic anhydrase 4 | 4.2.1.1 | 0.564 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.563 | |
| 1cnx | EG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.561 | |
| 4knm | E1E | Carbonic anhydrase 13 | 4.2.1.1 | 0.557 | |
| 3dbu | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.543 | |
| 4hu1 | V13 | Carbonic anhydrase 13 | 4.2.1.1 | 0.539 | |
| 3bl1 | BL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.536 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.531 | |
| 4knn | E1F | Carbonic anhydrase 13 | 4.2.1.1 | 0.525 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.523 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.522 | |
| 4k0z | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.522 | |
| 1i9p | IOE | Carbonic anhydrase 2 | 4.2.1.1 | 0.521 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.520 | |
| 3v2j | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.520 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.513 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.510 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.509 | |
| 3p80 | P80 | Pentaerythritol tetranitrate reductase | / | 0.508 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.508 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.506 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.497 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.497 | |
| 1bnu | AL3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.496 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.496 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.495 | |
| 4iah | 1DX | Alr2278 protein | / | 0.494 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.493 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.492 | |
| 5a01 | 12V | O-glycosyltransferase | / | 0.492 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.491 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.491 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.490 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.490 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.489 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.489 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.489 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.488 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.488 | |
| 4iae | 1DX | Alr2278 protein | / | 0.486 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.485 | |
| 2vat | COA | Acetyl-CoA--deacetylcephalosporin C acetyltransferase | 2.3.1.175 | 0.485 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.485 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.485 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.485 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.485 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.484 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.483 | |
| 1mxf | MTX | Putative pteridine reductase 2 | / | 0.482 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.482 | |
| 4jic | FMN | GTN Reductase | / | 0.482 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.481 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.481 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.480 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.480 | |
| 5fl4 | 9FK | Carbonic anhydrase 9 | 4.2.1.1 | 0.480 | |
| 1h62 | ANB | Pentaerythritol tetranitrate reductase | / | 0.478 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.478 | |
| 1w19 | T5P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.478 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.478 | |
| 2onm | ADP | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.478 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.477 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.477 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.477 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.476 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.476 | |
| 1n95 | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.475 | |
| 1n95 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.475 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.475 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.475 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.475 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.475 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.474 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.474 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.473 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.473 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.473 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.473 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.473 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.473 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.472 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.472 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.471 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.471 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.471 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.471 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.471 | |
| 1dtp | APU | Diphtheria toxin | / | 0.470 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.470 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.470 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.470 | |
| 4h9t | HL4 | Phosphotriesterase | / | 0.470 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.470 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.469 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.469 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.469 | |
| 2std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.469 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.469 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.469 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.469 | |
| 4ke1 | 1R6 | Beta-secretase 1 | 3.4.23.46 | 0.469 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.468 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.468 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.468 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.468 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.467 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.467 | |
| 4ca8 | 3ES | Angiotensin-converting enzyme | 3.4.15.1 | 0.467 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.467 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.466 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.466 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.466 | |
| 4n1g | CEI | Obelin | / | 0.466 | |
| 4rnw | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.466 | |
| 6std | MS2 | Scytalone dehydratase | 4.2.1.94 | 0.466 | |
| 2b4d | COA | Diamine acetyltransferase 1 | / | 0.465 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.465 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.465 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.465 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.465 | |
| 3hlw | CE3 | Beta-lactamase | / | 0.465 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.465 | |
| 1e2n | RCA | Thymidine kinase | / | 0.464 | |
| 1m9a | GTX | Glutathione S-transferase class-mu 26 kDa isozyme | 2.5.1.18 | 0.464 | |
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.464 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.464 | |
| 3myu | VIB | High affinity transport system protein p37 | / | 0.464 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.464 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.464 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.464 | |
| 1n5q | TNC | ActVA 6 protein | / | 0.463 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.463 | |
| 2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.463 | |
| 3hgs | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.463 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.463 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.462 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.462 | |
| 1qtq | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.462 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.462 | |
| 2fxu | BID | Actin, alpha skeletal muscle | / | 0.462 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.462 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.462 | |
| 3vil | SA0 | Beta-glucosidase | / | 0.462 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.462 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.462 | |
| 4gd4 | 0WS | Lysine-specific demethylase 4A | 1.14.11 | 0.462 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.461 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.461 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.461 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.461 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.461 | |
| 3kjg | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.461 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.461 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.461 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.461 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.461 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.460 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.460 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.460 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.460 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.460 | |
| 3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.460 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 3faz | NOS | Purine nucleoside phosphorylase | / | 0.460 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.460 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.460 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.460 | |
| 3zhu | TD8 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.460 | |
| 4b64 | NAP | L-ornithine N(5)-monooxygenase | / | 0.460 | |
| 4e2y | JHZ | Methyltransferase | / | 0.460 | |
| 4fr8 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.460 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.460 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.459 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.459 | |
| 2ydb | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.459 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.459 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.459 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.458 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.458 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.458 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.458 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.458 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.458 | |
| 3hdq | GDU | UDP-galactopyranose mutase | / | 0.458 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.458 | |
| 3p0e | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.458 | |
| 3qiz | QI2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.458 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.458 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.458 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.458 | |
| 1cq8 | PY6 | Aspartate aminotransferase | 2.6.1.1 | 0.457 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.457 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.457 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.457 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.457 | |
| 3sl2 | ATP | Sensor histidine kinase WalK | / | 0.457 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.457 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.457 | |
| 4e2d | FMN | Dehydrogenase | / | 0.457 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.457 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.457 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.457 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.457 | |
| 4yj2 | GTP | Tubulin alpha-1B chain | / | 0.457 | |
| 6gsu | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.457 | |
| 1akc | PPE | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.456 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.456 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.456 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.456 | |
| 1uxy | EPU | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.456 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.456 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.456 | |
| 3ksq | Z96 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.456 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.456 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.456 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 4r1f | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.456 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.456 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.455 | |
| 1j4h | SUB | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.455 | |
| 1n95 | FTH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.455 | |
| 1u1d | 181 | Uridine phosphorylase | 2.4.2.3 | 0.455 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.455 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3dhb | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.455 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.455 | |
| 3myt | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.455 | |
| 3tvq | DQH | Multifunctional cyclase-dehydratase-3-O-methyl transferase TcmN | 2.1.1 | 0.455 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.455 | |
| 4cf6 | CBD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.455 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.455 | |
| 4tmb | FMN | Old yellow enzyme | / | 0.455 | |
| 4yp6 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.455 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.454 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.454 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.454 | |
| 1yqs | BSA | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.454 | |
| 2bxo | OPB | Serum albumin | / | 0.454 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.454 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.454 | |
| 2g20 | L1A | Renin | 3.4.23.15 | 0.454 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.454 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.454 | |
| 3giy | FMN | (S)-mandelate dehydrogenase | 1.1.99.31 | 0.454 | |
| 3hdy | GDU | UDP-galactopyranose mutase | / | 0.454 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.454 | |
| 3mtw | M3R | Xaa-Pro dipeptidase, putative | / | 0.454 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 3w3l | RX8 | Toll-like receptor 8 | / | 0.454 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.454 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.454 | |
| 1al8 | DHP | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.453 | |
| 1ld8 | U49 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.453 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.453 | |
| 1odj | GMP | Purine nucleoside phosphorylase | / | 0.453 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.453 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.453 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.453 | |
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 3ewk | FAD | Sensory box histidine kinase/response regulator | / | 0.453 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.453 | |
| 5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.453 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.452 | |
| 1kp3 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.452 | |
| 1n2j | PAF | Pantothenate synthetase | 6.3.2.1 | 0.452 | |
| 1s64 | 778 | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.452 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.452 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.452 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.452 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.452 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.452 | |
| 2xda | JPS | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.452 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.452 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.452 | |
| 4g8j | THM | Uridine phosphorylase | / | 0.452 | |
| 4i8x | 6P3 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.452 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.452 | |
| 4nv1 | 0FX | Formyl transferase | / | 0.452 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.452 | |
| 4xr9 | NAD | CalS8 | / | 0.452 | |
| 5er0 | FAD | Uncharacterized NAD(FAD)-dependent dehydrogenase | / | 0.452 | |
| 1a27 | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.451 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.451 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.451 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.451 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.451 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.451 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.451 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.451 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.451 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.451 | |
| 1u1c | BAU | Uridine phosphorylase | 2.4.2.3 | 0.451 | |
| 2d3a | ADP | Glutamine synthetase root isozyme 3 | 6.3.1.2 | 0.451 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.451 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.451 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.451 | |
| 3akm | 11D | Fatty acid-binding protein, intestinal | / | 0.451 | |
| 3gf4 | UPG | UDP-galactopyranose mutase | 5.4.99.9 | 0.451 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.451 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.451 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.451 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.451 | |
| 4e2b | FMN | Dehydrogenase | / | 0.451 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.451 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.451 | |
| 4y17 | LAE | Transcriptional regulator of ftsQAZ gene cluster | / | 0.451 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.450 | |
| 1h65 | GDP | Translocase of chloroplast 34 | 3.6.5 | 0.450 | |
| 1hku | NAD | C-terminal-binding protein 1 | 1.1.1 | 0.450 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.450 | |
| 2qw0 | 34Z | 4-chlorobenzoyl CoA ligase | / | 0.450 | |
| 2rd2 | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.450 | |
| 2wqp | WQP | Polysialic acid capsule biosynthesis protein SiaC | / | 0.450 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.450 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.450 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.450 | |
| 3mj4 | URM | UDP-galactopyranose mutase | / | 0.450 | |
| 3qft | FAD | NADPH--cytochrome P450 reductase | / | 0.450 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.450 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.450 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.450 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.449 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1jzq | ILA | Isoleucine--tRNA ligase | 6.1.1.5 | 0.449 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.449 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.449 | |
| 2v5a | LZL | Biotin carboxylase | 6.3.4.14 | 0.449 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.449 | |
| 2z9d | FMN | FMN-dependent NADH-azoreductase | / | 0.449 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.449 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.449 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.449 | |
| 3zht | TD9 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.449 | |
| 4boe | CLR | Japanin | / | 0.449 | |
| 4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.449 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 5bnw | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.449 | |
| 1sa4 | JAN | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.448 | |
| 2a84 | ATP | Pantothenate synthetase | 6.3.2.1 | 0.448 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.448 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.448 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.448 | |
| 3cav | CI2 | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.448 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.448 | |
| 3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.448 | |
| 3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.448 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.448 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.448 | |
| 3w3n | RX8 | Toll-like receptor 8 | / | 0.448 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.448 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.448 | |
| 4lnb | ED5 | CaaX farnesyltransferase beta subunit Ram1 | / | 0.448 | |
| 4lut | DCS | Alanine racemase | / | 0.448 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.448 | |
| 4uoc | NCN | CinA-like protein | / | 0.448 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.448 | |
| 4xba | 5GP | Aprataxin-like protein | 3 | 0.448 | |
| 1aka | PLP | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.447 | |
| 1bl4 | AP1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.447 | |
| 1gax | VAA | Valine--tRNA ligase | 6.1.1.9 | 0.447 | |
| 1gtr | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.447 | |
| 1nzx | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.447 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.447 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.447 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.447 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 3hxc | BD6 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.447 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3pdq | KC6 | Lysine-specific demethylase 4A | 1.14.11 | 0.447 | |
| 3wcz | NAP | Aldo-keto reductase AKR2E4 | / | 0.447 | |
| 4ejv | LCL | Transcriptional regulator TcaR | / | 0.447 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.447 | |
| 4w5k | PLP | Aspartate aminotransferase, mitochondrial | / | 0.447 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.446 | |
| 1qpf | 858 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.446 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.446 | |
| 1zdw | FLV | Prenyltransferase | / | 0.446 | |
| 2dc1 | NAD | Probable L-aspartate dehydrogenase | / | 0.446 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.446 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.446 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.446 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.446 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.446 | |
| 3t64 | DU3 | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.446 | |
| 3uov | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.446 | |
| 3zhr | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.446 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.446 | |
| 4ehy | ADP | Tetraacyldisaccharide 4'-kinase | / | 0.446 | |
| 4f5d | C2E | Stimulator of interferon genes protein | / | 0.446 | |
| 4i9n | 1E5 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.446 | |
| 4jbs | P52 | Endoplasmic reticulum aminopeptidase 2 | 3.4.11 | 0.446 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.446 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.446 | |
| 1ahg | TYR_PLP | Aspartate aminotransferase | 2.6.1.1 | 0.445 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.445 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.445 | |
| 1xvv | CCQ | L-carnitine CoA-transferase | / | 0.445 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.445 | |
| 2gqg | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.445 | |
| 2q3r | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.445 | |
| 2q85 | 973 | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.445 | |
| 2x91 | LPR | Angiotensin-converting enzyme | 3.4.15.1 | 0.445 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 2yj4 | ATP | Copper-transporting ATPase | / | 0.445 | |
| 2z1q | FAD | Acyl-CoA dehydrogenase | / | 0.445 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.445 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3nbr | ASD | Steroid Delta-isomerase | 5.3.3.1 | 0.445 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.445 | |
| 3ppr | 4CS | Glycine betaine/carnitine/choline-binding protein OpuCC | / | 0.445 | |
| 3wyc | NAP | Meso-diaminopimelate D-dehydrogenase | 1.4.1.16 | 0.445 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 4c49 | HCY | Corticosteroid-binding globulin | / | 0.445 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.445 | |
| 4jxx | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.445 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.445 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.445 | |
| 4v12 | POG | MaoC like domain protein | / | 0.445 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.445 | |
| 4xrb | NDP | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc | / | 0.445 | |
| 4yp1 | 2BA | Stimulator of interferon genes protein | / | 0.445 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.445 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.445 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 1fkf | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.444 | |
| 1o1s | 1NH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.444 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.444 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.444 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.444 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.444 | |
| 3bj7 | COA | Diamine acetyltransferase 1 | / | 0.444 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.444 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.444 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.444 | |
| 4h6k | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.444 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.444 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 1c7o | PPG | Hemolysin | / | 0.443 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.443 | |
| 1obb | NAD | Alpha-glucosidase | 3.2.1.20 | 0.443 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.443 | |
| 2e1m | FAD | L-glutamate oxidase | / | 0.443 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.443 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.443 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.443 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.443 | |
| 2ydd | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.443 | |
| 3b6p | TMP | Three-prime repair exonuclease 1 | 3.1.11.2 | 0.443 | |
| 3lzw | NAP | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.443 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.443 | |
| 3td7 | FAD | Probable FAD-linked sulfhydryl oxidase R596 | 1.8.3.2 | 0.443 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.443 | |
| 4fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.443 | |
| 4fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.443 | |
| 4lng | JAN | CaaX farnesyltransferase beta subunit Ram1 | / | 0.443 | |
| 5c1g | GDU | Histo-blood group ABO system transferase | / | 0.443 | |
| 1j37 | X8Z | Angiotensin-converting enzyme | 3.4.15.1 | 0.442 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.442 | |
| 1wxj | IPL | Tryptophan synthase alpha chain | / | 0.442 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.442 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.442 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.442 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.442 | |
| 2j08 | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.442 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.442 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.442 | |
| 3da2 | 4MD | Carbonic anhydrase 13 | 4.2.1.1 | 0.442 | |
| 3ivc | FG4 | Pantothenate synthetase | 6.3.2.1 | 0.442 | |
| 3vsx | R32 | Renin | 3.4.23.15 | 0.442 | |
| 4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.442 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.442 | |
| 4jsr | 1NQ | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.442 | |
| 4qfy | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.442 | |
| 4rvf | TYD | D-mycarose 3-C-methyltransferase | / | 0.442 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.441 | |
| 1eio | GCH | Gastrotropin | / | 0.441 | |
| 1kbi | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.441 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.441 | |
| 1qx4 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.441 | |
| 1qy2 | IPZ | Major urinary protein 1 | / | 0.441 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.441 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.441 | |
| 2bju | IH4 | Plasmepsin-2 | 3.4.23.39 | 0.441 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.441 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.441 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.441 | |
| 3e23 | SAM | Uncharacterized protein | / | 0.441 | |
| 3euf | BAU | Uridine phosphorylase 1 | / | 0.441 | |
| 3kyb | FMN | UDP-galactopyranose mutase | 5.4.99.9 | 0.441 | |
| 3mj4 | FAD | UDP-galactopyranose mutase | / | 0.441 | |
| 3u8l | 09Q | Acetylcholine-binding protein | / | 0.441 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
| 3v2u | ATP | Protein GAL3 | / | 0.441 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.441 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 4c77 | N01 | Phenylacetone monooxygenase | 1.14.13.92 | 0.441 | |
| 4rp8 | ASC | Ascorbate-specific PTS system EIIC component | / | 0.441 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.441 | |
| 4x7v | MIV | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.441 | |
| 1b8v | NAD | Malate dehydrogenase | / | 0.440 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.440 | |
| 1eyy | NAP | NADP-dependent fatty aldehyde dehydrogenase | 1.2.1.4 | 0.440 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.440 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1kw0 | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.440 | |
| 1n77 | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.440 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.440 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.440 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.440 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.440 | |
| 2xpc | 051 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.440 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.440 | |
| 3inr | GDU | UDP-galactopyranose mutase | 5.4.99.9 | 0.440 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.440 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.440 | |
| 4de2 | DN3 | Beta-lactamase | / | 0.440 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.440 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4hms | FMN | Phenazine biosynthesis protein PhzG | 1.4 | 0.440 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.440 | |
| 4u3j | GTP | Tubulin beta chain | / | 0.440 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.440 | |
| 4yer | ADP | Antibiotic ABC transporter, ATP-binding protein, putative | / | 0.440 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.440 | |
| 5eio | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.440 |