Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3sbdGNPRas-related C3 botulinum toxin substrate 1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3sbdGNPRas-related C3 botulinum toxin substrate 1/1.000
1e96GTPRas-related C3 botulinum toxin substrate 1/0.613
4mitGTPRho-related protein racC/0.600
2qmeGCPRas-related C3 botulinum toxin substrate 3/0.590
3sbeGNPRas-related C3 botulinum toxin substrate 1/0.584
4js0GNPCell division control protein 42 homolog/0.576
3a58GNPGTP-binding protein RHO1/0.572
1a2bGSPTransforming protein RhoA/0.571
1xtsGTPGTP-binding protein Rheb/0.568
1zbdGTPRas-related protein Rab-3A/0.568
1kmqGNPTransforming protein RhoA/0.566
3kkoGNPRas-related protein M-Ras/0.566
2c5lGTPGTPase HRas/0.565
2rgeGNPGTPase HRas/0.565
3oesGNPGTPase RhebL1/0.564
4lhwGNPRas-related protein Rab-8A/0.564
3w3zGTPGTP-binding nuclear protein Ran/0.561
4nyjGNPGTPase HRas/0.561
4nyiGNPGTPase HRas/0.557
1cxzGSPTransforming protein RhoA/0.556
3eg5GNPCell division control protein 42 homolog/0.555
3ddcGNPGTPase HRas/0.553
3lbnGNPGTPase HRas/0.552
2rgcGNPGTPase HRas/0.551
3bbpGTPRas-related protein Rab-6A/0.551
3i3sGNPGTPase HRas/0.551
2gcpGSPRho-related GTP-binding protein RhoC/0.550
4dltGNPGTPase HRas/0.550
3kz1GSPTransforming protein RhoA/0.548
2rgbGNPGTPase HRas/0.547
3a6pGTPGTP-binding nuclear protein Ran/0.542
3oivGNPGTPase HRas/0.540
3v4fGNPGTPase HRas/0.540
4hdoGNPRas-related protein Rap-1b/0.537
1mh1GNPRas-related C3 botulinum toxin substrate 1/0.536
1s1cGNPTransforming protein RhoA/0.536
2fe4GDPRas-related protein Rab-6B/0.536
5hpyGDPTransforming protein RhoA/0.536
3pitGNPRas-related protein M-Ras/0.534
2fjuGSPRas-related C3 botulinum toxin substrate 1/0.532
2ov2GCPRas-related C3 botulinum toxin substrate 3/0.531
3nbzGTPGTP-binding nuclear protein Ran/0.531
5dhaGNPGTP-binding nuclear protein Ran/0.531
1g17GNPRas-related protein SEC4/0.530
3lbhGNPGTPase HRas/0.529
4k81GTPGTPase HRas/0.528
4hdqGNPRas-related protein Rap-1b/0.527
1ibrGNPGTP-binding nuclear protein Ran/0.524
3l8yGNPGTPase HRas/0.523
3oiwGNPGTPase HRas/0.523
3lawGNPRas-related protein Rab-7a/0.522
3rabGNPRas-related protein Rab-3A/0.522
4dlwGNPGTPase HRas/0.522
4rkfGNPRas-related protein Rab-3/0.522
1t91GTPRas-related protein Rab-7a/0.520
3e5hGNPRas-related protein Rab-28/0.520
3kucGDPRas-related protein Rap-1A/0.520
4gzlGNPRas-related C3 botulinum toxin substrate 1/0.519
1xtrGNPGTP-binding protein Rheb/0.517
1zd9GDPADP-ribosylation factor-like protein 8A/0.514
4dsnGCPGTPase KRas/0.514
1m7bGTPRho-related GTP-binding protein RhoE/0.513
4g0nGNPGTPase HRas/0.513
5b2zGNPGTPase HRas/0.512
3rs0GNPGTPase HRas/0.511
3tnfGNPRas-related protein Rab-8A/0.510
3rs4GNPGTPase HRas/0.508
1yzqGNPRas-related protein Rab-6A/0.507
3lbiGNPGTPase HRas/0.506
2w2xGSPRas-related C3 botulinum toxin substrate 2/0.504
3x1zGNPRas-related protein Rap-1b/0.503
5jljGNPGTP-binding nuclear protein Ran/0.503
1zc4GNPRas-related protein Ral-A/0.502
4dlxGNPGTPase HRas/0.501
4o2lGTPGTP-binding protein Rheb/0.501
5difGNPGTP-binding nuclear protein Ran/0.501
4l9sGDPGTPase HRas/0.500
4qxaGTPRas-related protein Rab-9A/0.500
2bkuGTPGTP-binding nuclear protein Ran/0.499
3rs5GNPGTPase HRas/0.499
4ol0GTPGTP-binding nuclear protein Ran/0.499
1k5dGNPGTP-binding nuclear protein Ran/0.498
1yhnGTPRas-related protein Rab-7a/0.498
3kudGDPGTPase HRas/0.498
4xvqGNPGTPase HRas/0.498
4tq9GDPGTPase KRas/0.497
3rs7GNPGTPase HRas/0.496
1zc3GNPRas-related protein Ral-A/0.495
2zetGTPRas-related protein Rab-27B/0.495
3tsoGNPRas-related protein Rab-25/0.495
4o25GTPGTP-binding protein Rheb/0.494
2x19GTPGTP-binding nuclear protein GSP1/CNR1/0.493
3oiuGNPGTPase HRas/0.492
3k8yGNPGTPase HRas/0.491
3rslGNPGTPase HRas/0.490
4dlzGNPGTPase HRas/0.486
3tgpGNPGTPase HRas/0.485
4l8gGDPGTPase KRas/0.485
1gwnGTPRho-related GTP-binding protein RhoE/0.483
1z2cGNPRho-related GTP-binding protein RhoC/0.483
1vg8GNPRas-related protein Rab-7a/0.482
3th5GNPRas-related C3 botulinum toxin substrate 1/0.482
4cymGCPRas-related protein Rab-32/0.480
3bc1GNPRas-related protein Rab-27A/0.479
3mjhGTPRas-related protein Rab-5A/0.478
3wyfGTPGTP-binding nuclear protein/0.478
4dlsGNPGTPase HRas/0.478
2g0nGDPRas-related C3 botulinum toxin substrate 3/0.477
4l9wGNPGTPase HRas/0.476
2ic5GDPRas-related C3 botulinum toxin substrate 3/0.475
1x1rGDPRas-related protein M-Ras/0.473
2ffqGSPRas-related protein Rab-6B/0.473
4dlvGNPGTPase HRas/0.472
4xoiGTPTransforming protein RhoA/0.472
3ea5GDPGTP-binding nuclear protein Ran/0.471
4o2rGDPGTP-binding protein Rheb/0.471
2p2lGDPRas-related C3 botulinum toxin substrate 1/0.470
1uadGNPRas-related protein Ral-A/0.469
2msdGNPMHC class I alpha chain/0.469
4lpkGDPGTPase KRas/0.469
3qbtGNPRas-related protein Rab-8A/0.468
1oixGDPRas-related protein Rab-11A/0.467
4dsoGSPGTPase KRas/0.467
4xvrGNPGTPase HRas/0.467
1lfdGNPGTPase HRas/0.464
2ce2GDPGTPase HRas/0.463
3cphGDPRas-related protein SEC4/0.461
4lucGDPGTPase KRas/0.461
4obeGDPGTPase KRas/0.461
2rggGNPGTPase HRas/0.460
1d5cGDPGTPase (Rab6)/0.458
2fg5GNPRas-related protein Rab-31/0.458
2ic5GNPRas-related C3 botulinum toxin substrate 3/0.458
4kvgGTPRas-related protein Rap-1A/0.457
1z2aGDPRas-related protein Rab-23/0.456
4gzmGSPRas-related C3 botulinum toxin substrate 1/0.456
3k9lGNPGTPase HRas/0.455
2j0vGDPRac-like GTP-binding protein ARAC7/0.452
4uj3GNPRas-related protein Rab-11A/0.450
2clsGTPRho-related GTP-binding protein Rho6/0.447
4epxGDPGTPase KRas/0.447
1n6lGTPRas-related protein Rab-5A/0.446
2cl6CAGGTPase HRas/0.446
3kkqGDPRas-related protein M-Ras/0.446
1z0aGDPRas-related protein Rab-2A/0.445
2bmeGNPRas-related protein Rab-4A/0.445
4ql3GDPGTPase KRas/0.445
4q03GDPGTPase KRas/0.443
4wa7GDPGTPase KRas/0.443
4lv6GDPGTPase KRas/0.442
4q02GDPGTPase KRas/0.441
1ow3GDPTransforming protein RhoA/0.440